Reverse vaccinology: Reverse vaccinology is an improvement on vaccinology that employs bioinformatics, pioneered by Rino Rappuoli and first used against Serogroup B meningococcus.Pizza et al.Naked DNA: Naked DNA is histone-free DNA that is passed from cell to cell during a gene transfer process called transformation or transfection. In transformation, purified or naked DNA is taken up by the recipient cell which will give the recipient cell a new characteristic or phenotype.TwinrixImmunization during pregnancy: Immunization during pregnancy, that is the administration of a vaccine to a pregnant woman, is not a routine event as it is generally preferred to administer vaccines either prior to conception or in the postpartum period. When widespread vaccination is used, the risk for an unvaccinated pregnant patient to be exposed to a related infection is low, allowing for postponement, in general, of routine vaccinations to the postpartum period.HIV Vaccine Trials Network: The HIV Vaccine Trials Network (HVTN) is a non-profit organization which connects physicians and scientists with activists and community educators for the purpose of conducting clinical trials seeking a safe and effective HIV vaccine. Collaboratively, research professionals and laypeople review potential vaccines for safety, immune response, and efficacy.Peptide vaccine: A peptide vaccine is any peptide which serves to immunize an organism against a pathogen. Peptide vaccine are often synthetic and mimic naturally occurring proteins from pathogens.Conjugate vaccine: A conjugate vaccine is created by covalently attaching a poor (polysaccharide) antigen to a carrier protein (preferably from the same microorganism), thereby conferring the immunological attributes of the carrier to the attached antigen.VaccinationCervarixGlobal Vaccines: Global Vaccines, Inc is a mission-driven non-profit company applying state-of-the-art science and innovative business strategies to design and develop affordable vaccines for people in poor countries.Meningococcal vaccineAS04: AS04 (Aka. "Adjuvant System 04") is a trade name for combination of adjuvants used in various vaccine product by GlaxoSmithKline (GSK), in particular the Fendrix Hepatitis B vaccine.Pertussis vaccineDenise Faustman: Denise L. Faustman, (born 1958) is a U.Cholera vaccineTyphoid vaccineSmallpox demon: or smallpox devil is a demon which was believed to be responsible for causing smallpox in medieval Japan. In those days, people tried to appease the smallpox demon by assuaging his anger, or they tried to attack the demon since they had no other effective treatment for smallpox.MVA85A: MVA85A (modified vaccinia Ankara 85A) is a new-generation vaccine against tuberculosis developed by researchers at Oxford University. This vaccine produces higher levels of long-lasting cellular immunity when used together with the older TB vaccine BCG.Greyfriars, King's Lynn: Greyfriars, King's Lynn was a Franciscan friary in Norfolk, England. The tower, known as Greyfriars Tower () survives.DPT vaccineImmunologic adjuvant: In immunology, an adjuvant is a component that potentiates the immune responses to an antigen and/or modulates it towards the desired immune responses. The word “adjuvant” comes from the Latin word adiuvare, meaning to help or aid.Anthrax Vaccine Immunization Program: The Anthrax Vaccine Immunization Program (AVIP), is the name of the policy set forth by the U.S.ImmunizationMalcolm BrabantPlague vaccineRubella vaccineCocooning (immunization): Cocooning, also known as the Cocoon Strategy, is a vaccination strategy that has been recommended by the Centers for Disease Control and Prevention (CDC) in the United States since 2006. It aims to protect newborn infants from becoming infected with pertussis by administering DTaP/Tdap (tetanus, diphtheria and acellular pertussis) booster vaccine to mothers, family members and any individuals who would come into regular contact with the newborn infant.Influenza A virus subtype H1N1: Influenza A (H1N1) virus is the subtype of influenza A virus that was the most common cause of human influenza (flu) in 2009, and is associated with the 1918 outbreak known as the Spanish Flu.Virus-like particle: Virus-like particles resemble viruses, but are non-infectious because they do not contain any viral genetic material. The expression of viral structural proteins, such as Envelope or Capsid, can result in the self-assembly of virus like particles (VLPs).Nasal administrationCytomegalovirus vaccine: A Cytomegalovirus vaccine is a vaccine to prevent cytomegalovirus (CMV) infection or to prevent it re-activation in those who are already infected. As of 2014 no such a vaccine exists, although a number of vaccine candidates are under investigation.CD4 immunoadhesin: CD4 immunoadhesin is a recombinant fusion protein consisting of a combination of CD4 and the fragment crystallizable region.Universal Immunization Programme: Universal Immunization Programme is a vaccination program launched by the Government of India in 1985. It became a part of Child Survival and Safe Motherhood Programme in 1992 and is currently one of the key areasPlaque reduction neutralization test: The Plaque reduction neutralization test is used to quantify the titre of neutralising antibody for a virus.VZV immune globulin: VZV (varicella zoster virus) globulin is an immune system medication that is used mostly for immunosuppressed patients. It shortens the course of cutaneous disease and may protect against its dissemination.Polysorbate: Polysorbates are a class of emulsifiers used in some pharmaceuticals and food preparation. They are often used in cosmetics to solubilize essential oils into water-based products.Gross pathology: Gross pathology refers to macroscopic manifestations of disease in organs, tissues, and body cavities. The term is commonly used by anatomical pathologists to refer to diagnostically useful findings made during the gross examination portion of surgical specimen processing or an autopsy.Injection site reaction: Injection site reactions are allergic reactions that result in cutaneous necrosis that may occur at sites of medication injection, typically presenting in one of two forms, (1) those associated with intravenous infusion or (2) those related to intramuscular injection.James, William; Berger, Timothy; Elston, Dirk (2005).Multiple cloning site: A multiple cloning site (MCS), also called a polylinker, is a short segment of DNA which contains many (up to ~20) restriction sites - a standard feature of engineered plasmids. Restriction sites within an MCS are typically unique, occurring only once within a given plasmid.List of GlaxoSmithKline products: This is a list of products manufactured by the multinational pharmaceutical, biologics, vaccines and consumer healthcare company GlaxoSmithKline.Eva Engvall: Eva Engvall, born 1940, is one of the scientists who invented ELISA in 1971.Eva Engvall, The Scientist 1995, 9(18):8Kalinite: Kalinite is a mineral composed of hydrated potassium aluminium sulfate (a type of alum). It is a fibrous monoclinic alum, distinct from isometric potassium alum,American Mineralogist (1923) 8:15 named in 1868.Aluminium hydroxide oxide: (additive)Japanese encephalitis vaccineColes PhillipsSqualaneVirulence: Virulence is, by MeSH definition, the degree of pathogenicity within a group or species of parasites as indicated by case fatality rates and/or the ability of the organism to invade the tissues of the host. The pathogenicity of an organism - its ability to cause disease - is determined by its virulence factors.Cell-mediated immunity: Cell mediated immunity is an immune response that does not involve antibodies, but rather involves the activation of phagocytes, antigen-specific cytotoxic T-lymphocytes, and the release of various cytokines in response to an antigen. Historically, the immune system was separated into two branches: humoral immunity, for which the protective function of immunization could be found in the humor (cell-free bodily fluid or serum) and cellular immunity, for which the protective function of immunization was associated with cells.Temporal analysis of products: Temporal Analysis of Products (TAP), (TAP-2), (TAP-3) is an experimental technique for studyingRepros Therapeutics: Repros Therapeutics Inc. (NASDAQ: RPRX), is a US-based development stage biopharmaceutical company headquartered in The Woodlands, Texas.
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