Trophoblast: Trophoblasts (from Greek trephein: to feed, and blastos: germinator) are cells forming the outer layer of a blastocyst, which provide nutrients to the embryo and develop into a large part of the placenta. They are formed during the first stage of pregnancy and are the first cells to differentiate from the fertilized egg.Placenta: The placenta (also known as afterbirth) is an organ that connects the developing fetus to the uterine wall to allow nutrient uptake, waste elimination, and gas exchange via the mother's blood supply, fight against internal infection and produce hormones to support pregnancy. The placenta provides oxygen and nutrients to growing babies and removes waste products from the baby's blood.Prenatal nutrition: Nutrition and weight management before and during :pregnancy has a profound effect on the development of infants. This is a rather critical time for healthy fetal development as infants rely heavily on maternal stores and nutrient for optimal growth and health outcome later in life.Gestational choriocarcinoma: Gestational choriocarcinoma is a malignant trophoblastic tumour arising from any gestational event during pregnancy in the reproductive female. Women with gestational choriocarcinoma may present with abnormal vaginal bleeding, persistent markedly elevated βhCG, or a history of prior pregnancy.Decidual reaction: The decidual reaction is the changes in the endometrium of the uterus that prepare it for implantation of an embryo. These changes are observed in each menstrual cycle and enhanced after implantation.Villitis of unknown etiology: Villitis of unknown etiology, abbreviated VUE, is an inflammatory process that involves the chorionic villi (villitis) whose cause (etiology) is not known. VUE is associated with recurrent miscarriage and intrauterine growth restriction, and recurs in subsequent pregnancies.Immunosurgery: Immunosurgery is a method of removing an external cell layer of an object. Immunosurgery is to expose the specimen to a solution containing antibodies against the object, remove that solution and subsequently expose the object to complement.Chorion (egg): The chorion is the outermost membrane around the embryo in mammals, birds and reptiles. It develops from an outer fold on the surface of the yolk sac, which lies outside the vitteline envelope and is developed by the follicle cells while the egg is in the ovary.Transplacental carcinogenesis: Transplacental carcinogenesis is a series of genotypic and/or phenotypic changes in the cells of a fetus due to in utero exposure to carcinogens. Specifically, these changes are identified as malignant by virtue of their metastatic potential.Somatotropin family: The Somatotropin family is a protein family whose titular representative is somatotropin, also known as growth hormone, a hormone that plays an important role in growth control. Other members include choriomammotropin (lactogen), its placental analogue; prolactin, which promotes lactation in the mammary gland, and placental prolactin-related proteins; proliferin and proliferin related protein; and somatolactin from various fishes.Uterus transplantation: The uterine transplant is the surgical procedure whereby a healthy uterus is transplanted into a female organism of which the uterus is absent or diseased. As part of normal mammalian sexual reproduction, a diseased or absent uterus does not allow normal embryonic implantation, effectively rendering the female infertile.Endometrium: The endometrium is the inner mucous membrane of the mammalian uterus.Equine chorionic gonadotropin: Equine chorionic gonadotropin (eCG) is a gonadotropic hormone produced in the chorion of pregnant mares. Most commonly called pregnant mare's serum gonadotropin (PMSG) in the past, the hormone is commonly used in concert with progestogen to induce ovulation in livestock prior to artificial insemination.Gestational age: Gestational age (or menstrual age) is a measure of the age of a pregnancy where the origin is the woman's last normal menstrual period (LMP), or the corresponding age as estimated by other methods. Such methods include adding 14 days to a known duration since fertilization (as is possible in in vitro fertilization), or by obstetric ultrasonography.Sylvia Lawler: Sylvia Dorothy Lawler, born Sylvia Dorothy Corben and later remarried as Sylvia Dorothy Bagshawe (1922–1996), worked in the field of human genetics.Mature messenger RNA: Mature messenger RNA, often abbreviated as mature mRNA is a eukaryotic RNA transcript that has been spliced and processed and is ready for translation in the course of protein synthesis. Unlike the eukaryotic RNA immediately after transcription known as precursor messenger RNA, it consists exclusively of exons, with all introns removed.STARD7: StAR-related lipid transfer domain protein 7 (STARD7) or gestational trophoblastic tumor gene-1 (GTT1) is a lipid transporter that specifically binds and transports phosphatidylcholine between membranes.Haptotaxis: Haptotaxis (from Greek ἅπτω (hapto, "touch, fasten") and τάξις (taxis, "arrangement, order")) is the directional motility or outgrowth of cells, e.g.Interstitial pregnancyPlacental site trophoblastic tumor: Placental site trophoblastic tumor is a form of gestational trophoblastic disease, which is thought to arise from intermediate trophoblast.
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