Thyroglobulin: Thyroglobulin (Tg) is a 660 kDa, dimeric protein produced by the follicular cells of the thyroid and used entirely within the thyroid gland. Thyroglobulin protein accounts for approximately half of the protein content of the thyroid gland.Follicular cellAutoimmune thyroiditisMonoiodotyrosineRiedel's thyroiditisThyroid cancerIodine deficiencyGoitreThyrotropic cellIodothyronine deiodinase: Iodothyronine deiodinases ( and ) are a subfamily of deiodinase enzymes important in the activation and deactivation of thyroid hormones. Thyroxine (T4), the precursor of 3,5,3’-triiodothyronine (T3) is transformed into T3 by deiodinase activity.ThyroidectomyTriiodideAutoantibody: An autoantibody is an antibody (a type of protein) produced by the immune system that is directed against one or more of the individual's own proteins. Many autoimmune diseases, (notably lupus erythematosus), are caused by such autoantibodies.Symptoms and signs of Graves' disease: Virtually all the symptoms and signs of Graves' disease result from the direct and indirect effects of hyperthyroidism, with exceptions being Graves' ophthalmopathy, goitre and pretibial myxedema (which are caused by the autoimmune processes of Graves' disease). These clinical manifestations are dramatic and involve virtually every system in the body.DiiodotyrosineThyroid hormone: The thyroid hormones, triiodothyronine (T3) and its prohormone, thyroxine (T4), are tyrosine-based hormones produced by the thyroid gland that are primarily responsible for regulation of metabolism. T3 and T4 are partially composed of iodine (see molecular model).Congenital hypothyroidismRO5166017: RO-5166017 is a drug developed by Hoffmann-La Roche which acts as a potent and selective agonist for the trace amine-associated receptor 1, with no significant activity at other targets. This is important for the study of the TAAR1 receptor, as while numerous other compounds are known which act as TAAR1 agonists, such as methamphetamine, MDMA and 3-iodothyronamine, all previously known TAAR1 agonists are either weak and rapidly metabolized (endogenous ligands), or have strong pharmacological activity at other targets (amphetamines, thyronamines), making it very difficult to assess which effects are due to TAAR1 activation.ArtesunateHypothyroidismHashimoto's encephalopathy: Hashimoto's Encephalopathy is a rare autoimmune disease associated with Hashimoto's thyroiditis. It was first described in 1966.Reverse triiodothyronineCell ablation: Cell ablation (also known as tissue ablation) is a biotechnological tool for studying cell lineage and/or function and is a form of ablation. The process consists of selectively destroying one or multiple cells in a given organism by any chosen means.Subtherapeutic antibiotic use in swine: Antibiotics are commonly used in commercial swine production in the United States and around the world. They are used for disease treatment, disease prevention and control, and growth promotion.Thyroid dysgenesis: Thyroid agenesis (or thyroid dysgenesis) is a cause of congenital hypothyroidism where the thyroid is missing, ectopic, or severely underdeveloped.
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