MercaptopurineNucleotide salvage: A salvage pathway is a pathway in which nucleotides (purine and pyrimidine) are synthesized from intermediates in the degradative pathway for nucleotides.Hubert Chantrenne: Hubert Chantrenne (1918–2007) was a Belgian scientist, and one of the pioneers of molecular biology at the Université Libre de Bruxelles. He elucidated the messenger role played by the ribonucleic acid (RNA) in the synthesis of proteins in ribosome, organelles of the cellular cytoplasm.S-methyl-5'-thioinosine phosphorylase: S-methyl-5'-thioinosine phosphorylase (, MTIP, MTI phosphorylase, methylthioinosine phosphorylase) is an enzyme with system name S-methyl-5'-thioinosine:phosphate S-methyl-5-thio-alpha-D-ribosyl-transferase. This enzyme catalyses the following chemical reactionAzathioprineDaunorubicinCytarabineO-methyltransferase: An O-methylated flavonoid (OMT) is a type of methyltransferase enzyme transferring a methyl group on a molecule.PurineDeoxyuridine monophosphateMutagen: In genetics, a mutagen is a physical or chemical agent that changes the genetic material, usually DNA, of an organism and thus increases the frequency of mutations above the natural background level. As many mutations can cause cancer, mutagens are therefore also likely to be carcinogens.Purine nucleotide cycle: The Purine Nucleotide Cycle is a metabolic pathway in which fumarate is generated from aspartate in order to increase the concentration of Krebs cycle intermediates.Salway, J.Minimally differentiated acute myeloblastic leukemiaBiotransformation: Biotransformation is the chemical modification (or modifications) made by an organism on a chemical compound. If this modification ends in mineral compounds like CO2, NH4+, or H2O, the biotransformation is called mineralisation.
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