Transplacental: Transplacental refers to the ability of a toxin or pathogen to cross the physical and biological barriers of the placenta separating the mother and fetus, to whom such substances may be dangerous. This would include, for example, HIV and the drug thalidomide.Multiple Myeloma Research Foundation: right|240pxHU-336Developmental toxicity: Developmental toxicity is any structural or functional alteration, reversible or irreversible, which interferes with homeostasis, normal growth, differentiation, development or behavior, and which is caused by environmental insult (including drugs, lifestyle factors such as alcohol, diet, and environmental toxic chemicals or physical factors). Pathogens are generally included as well, despite some definitions not regarding biological organism as "toxic" by themselves.Lucio's phenomenon: Lucio's phenomenon is an unusual reaction seen almost exclusively in patients from the Caribbean and Mexico with diffuse, lepromatous leprosy, especially in untreated cases. It is characterised by recurrent crops of large, sharply demarcated, ulcerative lesions, affecting mainly the lower extremities, but may generalise and become fatal as a result of secondary bacterial infection and sepsis.Boronic acidBortezomibImmunosuppressive drug: Immunosuppressive drugs or immunosuppressive agents or antirejection medications are drugs that inhibit or prevent activity of the immune system. They are used in immunosuppressive therapy to:PhocomeliaErythema nodosumAngiodysplasia: In medicine (gastroenterology), angiodysplasia is a small vascular malformation of the gut. It is a common cause of otherwise unexplained gastrointestinal bleeding and anemia.Low-dose chemotherapy: Low-dose chemotherapy is being studied/used in the treatment of cancer to avoid the side effects of conventional chemotherapy. Historically, oncologists have used the highest possible dose that the body can tolerate in order to kill as many cancer cells as possible.PomalidomideMelphalanMouth ulcerPentoxifyllineBorderline lepromatous leprosy: Borderline lepromatous leprosy is a skin condition with numerous, symmetrical skin lesions.Congenital limb deformities: Congenital limb deformities are congenital musculoskeletal disorders which primarily affect the upper and lower limbs.Antileukemic drug: Antileukemic drugs, anticancer drugs that are used to treat one or more types of leukemia, include:Concentration effect: In the study of inhaled anesthetics, the concentration effect is the increase in the rate that the Fa(alveolar concentration)/Fi(inspired concentration) ratio rises as the alveolar concentration of that gas is increased. In simple terms, the higher the concentration of gas administered, the faster the alveolar concentration of that gas approaches the inspired concentration.Biological response modifiers: Biological response modifiers (BRMs) are substances that modify immune responses. They can be both endogenous (produced naturally within the body) and exogenous (as pharmaceutical drugs), and they can either enhance an immune response or suppress it.G-CSF factor stem-loop destabilising element