... increasing evidence from animal studies showing that cannabinoid drugs ... induce enduring neurobehavioral abnormalities in the ... The role of the endocannabinoid system (ECS) in female fertility has long been suspected and studied. Most studies through 2013 ... Another study have also shown, that healthy women, with higher lymphocyte FAAH, have lower blood AEA compared to aborting women ... Drugs in pregnancy N-acylethanolamine (NAE) Fonseca BM, Correia-da-Silva G, Almada M, Costa MA, Teixeira NA (2013). "The ...

Coadministration of moxifloxacin with other drugs that also prolong the QT interval or induce bradycardia (e.g., beta-blockers ... Animal studies suggest a risk of musculoskeletal harm in juveniles. Moxifloxacin is not believed to be associated with ... including those with conduction abnormalities. The safety of moxifloxacin in human patients under age 18 has not been ... Several drugs in this class, including moxifloxacin, are not licensed by the Food and Drug Administration for use in children, ...

... predicting individual susceptibility to drug-induced adverse effects causing weight gain and related metabolic abnormalities. ... In 2009, two very large genome-wide association studies of body mass index (BMI) confirmed the association of variants about ... The non-selective melanocortin receptor agonist afamelanotide (NDP-α-MSH) has been found to induce brain-derived neurotrophic ... This locus overlapped with the region previously identified in the 2009 studies. The rs489693 polymorphism, in particular, ...

Last, the electrophysiologist may administer various drugs (proarrhythmic agents) to induce arrhythmia (inducibility of VT/VF ... The doctor will pace each chamber of the heart one by one, looking for any abnormalities. Then the electrophysiologist tries to ... A cardiac electrophysiology study (EP test or EP study) is a minimally invasive procedure using catheters introduced through a ... and during any abnormal heart rhythms that can be induced. EP studies are used to investigate the cause, location of origin, ...

... regulation observed in disease states as seen in cells from patients with polycystic kidney disease or leading to drug-induced ... Her doctoral advisor was Jared Diamond and she studied lithium transport in human red blood cells as a way to understand ... The Ehrlich team hypothesizes that these abnormalities in function are consequences, at least in part, of altered intracellular ... Her laboratory uses calcium imaging combined with electrophysiological, biochemical, and molecular techniques to study the ...

"Severe and unrecognized dental abnormalities after drug-induced epidermal necrolysis". Archives of Dermatology. 145 (11): 1332- ... When third molars are ignored the prevalence rate for each tooth varies from study to study. In Caucasian studies mandibular ... Several UK studies have found the lower second premolar to be most commonly absent. Studies from Asian populations report that ... The most extensive studies have been in Caucasian populations and suggest a prevalence of 4-6%. One study looked at 33 previous ...

2008). "Case ascertainment and estimated incidence of drug-induced long-QT syndrome: study in Southwest France". British ... Patients taking haloperidol are at a higher risk if they also have electrolyte abnormalities (such as hypokalemia and/or ... or sudden cardiac death were in fact due to drug-induced QT prolongation and torsades de pointes. An observational study from ... the overall incidence of drug-induced QT prolongation is difficult to estimate. One study in France estimated that between 5-7 ...

Research on the effect of the psychedelic drug psilocybin shows that the altered state of consciousness induced by this drug ... Other studies addressing medication for PCC abnormalities, report that the PCC may only respond to stimulant treatments and the ... Finally, post-mortem studies show that the PCC in patients with ASD have cytoarchitectonic abnormalities, including reduced ... One study showed these reductions are prominent in the PCC.[non-primary source needed] Studies have shown that the ...

Some drugs being studied in different combinations include clonazepam, sodium valproate, piracetam, and primidone. Hormonal ... Identifying whether or not abnormalities in these pathways cause myoclonus may help in efforts to develop drug treatments and ... Other receptors with links to myoclonus include those for benzodiazepines, drugs that induce sleep, and for glycine, an ... and similar drugs, and is possibly a sign of high and/or rapidly increasing serum levels of these drugs. Myoclonic jerks caused ...

... pylori-infected patients compared to the drug alone. Yet another study showed that L. reuteri effectively suppressed H. pylori ... Dunham HJ, Casas IA, Edens FW, Parkhurst CR, Garlich JD, Dobrogosz WJ (1998). "Avian growth depression in chickens induced by ... A gut microbial imbalance, lacking in L. reuteri, was linked to behavioral abnormalities consistent with autism in humans. ... Since these studies were short-term, it is not known whether L. reuteri prevents tooth decay. However, since it is able to ...

In studying over 20 patients with misidentification syndromes, Christodoulou found electroencephalographic abnormalities in ... or drug-induced cognitive impairment. Among comorbid symptoms, paranoid psychotic symptoms, depressive psychotic symptoms and ... In several case studies, individuals with misidentification syndromes acted aggressively towards the object of ... Neurological dysfunction and neuropsychiatric abnormalities, in various forms, are now believed to be a central feature in DMSs ...

Aside from the use of epigenetic drugs to treat the epigenetic effects of sleep disorders, lifestyle changes that can induce ... Past studies have suggested that sleep deprivation may increase CpG methylation. One such study in mice showed that sleep ... This decreased histone acetylation has been linked to learning and memory deficits and abnormalities in individuals' circadian ... Several studies have associated them with circadian expression and sleep. Some studies have found altered microRNA expression ...

In a study, normal goat muscle fibers could be made myotonic by blocking the chloride conductance using myotonia inducing drugs ... A histochemical and ultrastructural study in the goat: comparison with abnormalities found in human myotonia dystrophica". The ... The study measured Fecal Egg Count (FEC) and Packed Cell Volume (PCV). Myotonic goats tended to have a lower body mass and a ... From the study above, it was found that a change in the nucleotide sequence caused a proline substitution for alanine residue ...

Neuroimaging studies have found abnormalities in the OFC in MDD and bipolar disorder. Consistent with the medial/reward and ... Rodent studies also demonstrate that lOFC to BLA projections are necessary for cue induced reinstatement of self administration ... could underlie drug seeking habits. Conduct disorder is associated with both structural abnormalities, and functional ... Although neuroimaging studies have provided evidence for dysfunction in a wide variety of psychiatric disorders, the enigmatic ...

DRESS syndrome-inducing drugs or their metabolites stimulate CD8+ T or CD4+ T cells to initiate autoimmune responses. Studies ... hematologic abnormalities, and systemic illness. Other synonymous names and acronyms include drug-induced hypersensitivity ... Bocquet H, Bagot M, Roujeau JC (December 1996). "Drug-induced pseudolymphoma and drug hypersensitivity syndrome (Drug Rash with ... Severe cutaneous adverse reactions Adverse drug reaction Drug allergy Drug intolerance Drug tolerance List of skin conditions ...

... nonsteroidal anti-inflammatory drug (NSAID) use is a risk factor for diverticular bleeding and NSAID-induced colonic ulcer; and ... A clotting abnormality and low platelet concentration in the blood should be immediately corrected if possible. Platelets ... One recent study identified poor kidney function (creatinine > 150 μm), age over 60 years, abnormal haemodynamic parameters on ... and various radiologic studies. The history in these patients should focus on factors that could be associated with potential ...

U.S. Department of Defense (DOD) grant to Ellen Heber-Katz for her study on drug-induced tissue regeneration and re-innervation ... LHRI researcher David Hungerford is credited with the discovery of the first genetic abnormality in cancer, called the ... DOD grant to Susan Gilmour for her study: Targeting increased polyamine transport in drug-resistant melanoma. NIH grant to ... NIH grant to Melvin Reichman for his study: New drug discovery paradigms for synucleinopathies. Giorgi Family Foundation grant ...

Acquired causes of tics include drug-induced tics, head trauma, encephalitis, stroke, and carbon monoxide poisoning. Most of ... Brain imaging studies are not usually warranted. In teenagers and adults presenting with a sudden onset of tics and other ... or symptoms may indicate that an MRI is needed to rule out brain abnormalities. TSH levels can be measured to rule out ... behavioral symptoms, a urine drug screen for cocaine and stimulants might be necessary. If a family history of liver disease is ...

... known to be purely genetic in nature while he demonstrates that many of these congenital malformations can also be drug induced ... Population genetic studies were carried out using non-functional markers, such as microsatellite markers, and functional ... Congenital heart abnormalities, Hearing loss and paediatric rare conditions. He also uses In-Silico, metabolomic and ... markers like immunogenetic markers (HLA, Cytokines), Pharmacogenomic genes (drug target, drug metabolism and drug transporter ...

Peet, M.; Peters, S. (February 1995). "Drug-induced mania". Drug Safety. 12 (2): 146-153. doi:10.2165/00002018-199512020-00007 ... Various lines of evidence from post-mortem studies and the putative mechanisms of anti-manic agents point to abnormalities in ... Studies show that the risk of switching while on an antidepressant is between 6-69 percent. Dopaminergic drugs such as reuptake ... CLOCK and DBP polymorphisms have been linked to bipolar in population studies, and behavioral changes induced by knockout are ...

... and immunomodulatory drugs). It is also important to consider the route of drug administration because there are some drugs ... A Pilot Study in a Multicultural Cancer Survivor Population with Chemotherapy-Induced Peripheral Neuropathy". International ... Pain and sensory abnormalities can persist for months or years after treatment completion. Some patients may experience " ... April 2012). "Anticancer drug oxaliplatin induces acute cooling-aggravated neuropathy via sodium channel subtype Na(V)1.6- ...

Drugs missing an ATC code, Drugs with no legal status, Articles containing unverified chemical infoboxes, Abandoned drugs, ... A study released in the 1950s found that women who were exposed to DES were at increased risk for cervical and vaginal clear ... It is known to induce the development of female secondary sexual characteristics in the case of female delayed puberty or ... DES exposed sons may also experience genital abnormalities but no conclusive increased risk of infertility. In the case of ...

Drugs with gadolinium-based contrasting agents can cause nephrogenic systemic fibrosis (NSF, or gadolinium-induced fibrosis) ... A 2020 study found Clariscan was retained more in the cerebrum, cerebellum, kidney and liver of rats than those injected with ... It is often used when viewing intracranial lesions with abnormal vascularity or abnormalities in the blood-brain barrier. ... "Gadoteric acid". Drug Information Portal. U.S. National Library of Medicine. "Gadoterate meglumine". Drug Information Portal. U ...

... or drug-induced vasculitis, but is not diagnostic. Electromyography. It is useful if a systemic vasculitis is suspected and ... French Vasculitis Study Group". Arthritis Rheum. 42 (12): 2674-81. doi:10.1002/1529-0131(199912)42:12. 3.0.CO;2-A. PMID ... and vascular wall abnormalities. Arteriography are not diagnostic in itself if other accessible areas for biopsy are present. ... Hypersensitivity vasculitis (allergic vasculitis). Usually due to a hypersensitivity reaction to a known drug. Drugs most ...

Dosages above approximately 300 mg/day risk inducing tardive dyskinesia. However, given the drug's fairly wide window of ... Another study in rats found tiapride's affinity for the septum, a limbic region, to be over thirty times as high as for the ... Cardiac abnormalities such as prolongation of the QT interval and torsades de pointes have also been observed. ... Tiapride is a drug that selectively blocks D2 and D3 dopamine receptors in the brain. It is used to treat a variety of ...

... fMRI and PET studies have shown abnormalities of the basal ganglia and hyper activation of the cortical areas. Studies have ... Central nervous system tumor Central pontine myelinolysis Cerebrovascular diseases Drug induced Infectious or post infectious ... The Epidemiological Study of Dystonia in Europe (ESDE) Collaborative (2000). "A prevalence study of primary dystonia in eight ... neurological abnormalities other than dystonia, abnormalities on brain imaging, particularly in the basal ganglia. To further ...

Clinical studies with these drugs, however, have shown the opposite. Mirtazapine, although not effective by itself, has been ... A new chapter about OCD in the DSM-5 (2013) now specifically includes drug-induced OCD.[citation needed] Atypical ... Similar to OCD, these disorders also exhibit abnormalities in the basal ganglia. This portion of the brain is responsible for ... These studies can be divided into four basic categories: (1) resting studies that compare brain activity at rest in patients ...

... from an intrinsic abnormality in the elastin and collagen components of the aortic wall. While definite genetic abnormalities ... Ultrasound studies are obtained on a regular basis (i.e. every 6 or 12 months) to follow the size of the aneurysm. Despite ... New lesions should not form at all when using this drug. Screening for an aortic aneurysm so that it may be detected and ... In short, raising HDL cholesterol is beneficial because it induces programmed cell death. The walls of a failing aorta are ...

Assessment and Management of Suspected Acute Drug-Induced Liver Injury During Clinical Trials in Adults with Chronic Viral ... This research study, published in the medical journal Gastroenterology in 1990, has been cited in almost 500 medical research ... "Effect of weight reduction on hepatic abnormalities in overweight patients". Gastroenterology. 99 (5): 1408-1413. doi:10.1016/ ... assessment and management of suspected acute drug-induced liver injury occurring during clinical trials in adults with chronic ...

Drugs that can induce psychosis experimentally or in a significant proportion of people include: Stimulants, such as ... although perceptual abnormalities such as changes in lighting, shading, streaks, or lines may be seen. Visual abnormalities may ... A research study of out-patients in psychiatric clinics found that 30 percent of religious patients attributed the cause of ... Drugs commonly alleged to induce psychotic symptoms include alcohol, cannabis, cocaine, amphetamines, cathinones, psychedelic ...

Fazio S (June 2009). "More clinical lessons from the FIELD study". Cardiovascular Drugs and Therapy. 23 (3): 235-241. doi: ... "the Agency has concluded that the totality of the scientific evidence no longer supports the conclusion that a drug-induced ... It is less commonly used compared than statins because it treats a different type of cholesterol abnormality to statins. While ... Multiple chemicals in Infobox drug, Multiple chemicals in an infobox that need indexing, Drug has EMA link, Drugboxes which ...