They display significant amino acid sequence homology. Sixteen cysteine residues, forming 8 disulfide bonds, are strictly ... Piscivorin has the following amino acid sequence. Piscivorin reduces high potassium-evoked smooth muscle contraction, but does ... A sequence comparison of piscivorin and other CRISP family proteins suggests that the Glu186 residue is the crucial site for ... The nucleotide sequence of piscivorin cDNA spans 1323 bp, containing an open reading frame of 240 codons. ...
Marcus F, Gontero B, Harrsch PB, Rittenhouse J (Mar 1986). "Amino acid sequence homology among fructose-1,6-bisphosphatases". ... Fructose bisphosphatase deficiency Fructose Gluconeogenesis Metabolism Marcus F, Harrsch PB (May 1990). "Amino acid sequence of ... IMPase and FBPase share a sequence motif (Asp-Pro-Ile/Leu-Asp-Gly/Ser-Thr/Ser) which has been shown to bind metal ions and ... do not show any significant sequence similarity to the enzymes from other organisms. The Bacillus subtilis enzyme is inhibited ...
It was subsequently cloned and sequenced by Radhey Gupta and coworkers. The amino acid sequence showed a strong homology to ... Waldinger D, Eckerskorn C, Lottspeich F, Cleve H (1988). "Amino-acid sequence homology of a polymorphic cellular protein from ... The cytoplasmic HSP60 contains a signal sequence of 26 amino acids on the N terminus. This sequence is highly degenerate and is ... With respect to the amino acid sequence, the cytoplasmic HSP60 has an N-terminal sequence not found in the mitochondrial ...
Amino acid sequence of MTA2 shares 68.2% homology with MTA1's sequence. MTA2 domains include, a BAH (Bromo-Adjacent Homology), ... inclusive of three protein-coding transcripts but predicted to code for two polypeptides of 688 amino acids and 495 amino acids ... The murine Mta2 consists of a 3.1-kb protein-coding transcript to code a protein of 668 amino acids, and five non-coding RNAs ... MTA2 was initially recognized as an MTA1 like 1 gene, named MTA1-L1, from a large scale sequencing of randomly selected clones ...
... they share gene sequence and amino acid sequence homology. They all also possess conserved amino acids that are important for ... those with a specific amino acid sequence (or motif) of glutamic acid-leucine-arginine (or ELR for short) immediately before ... The CC chemokine (or β-chemokine) proteins have two adjacent cysteines (amino acids), near their amino terminus. There have ... A loop of approximately ten amino acids follows the first two cysteines and is known as the N-loop. This is followed by a ...
... coding for 2,710 amino acids. TcdA and TcdB share 63% homology in their amino acid sequences. These genes are expressed during ... A centrally located hydrophobic domain containing a cluster of 172 highly conserved hydrophobic amino acids is thought to be ... which transfers a glucose molecule from UDP-Glucose and covalently attaches it to conserved amino acids in target molecules. ... Due to its homology with other proteins of similar function, as well as the location of the gene between tcdA and tcdB, tcdE is ...
Over 200 subtilases are presently known, more than 170 of which with their complete amino acid sequence. Subtilase is ... Based on sequence homology, a subdivision into six families has been proposed. The proprotein-processing endopeptidases kexin, ... These preferentially cleave C-terminally to paired basic amino acids. Members of this subfamily can be identified by subtly ... with the mature catalytic domains containing approximately 375 amino acids. The defining features of these enzymes are a unique ...
Kleeman TA, Wei D, Simpson KL, First EA (Jun 1997). "Human tyrosyl-tRNA synthetase shares amino acid sequence homology with a ... Living cells translate DNA sequences into RNA sequences and then into protein sequences. Proteins are chains of amino acids, ... As the protein grows, each amino acid is added to the end by an enzyme called transfer RNA (tRNA). Each amino acid has its own ... by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, ...
IL-36ra is 155 amino acids long and lacks a signal sequence. IL-36ra shares with IL-1ra 52% homology in the amino acid sequence ... IL-13 is very similar to IL-4 in amino acid sequence and structure. They also used the same type II IL-4 receptor to activate ... At the time of the assignment of these names, there was no amino acid sequence analysis known and the terms were used to define ... IL-1ra is synthesized as a preprotein containing a classical 25 amino acid long signal sequence that allows secretion via the ...
There is a high homology in the amino acid sequence within each family. Each family couples to the same second messenger ...
Lottspeich F, Geiger R, Henschen A, Kutzbach C (1980). "N-Terminal amino acid sequence of human urinary kallikrein homology ... Complete amino acid sequence and sites of glycosylation". Int. J. Pept. Protein Res. 33 (4): 237-49. doi:10.1111/j.1399- ... 1986). "N-terminal amino acid sequence of human urinary prokallikrein". J. Biochem. 99 (3): 989-92. doi:10.1093/oxfordjournals. ... Kellermann J, Lottspeich F, Geiger R, Deutzmann R (1988). "Human urinary kallikrein--amino acid sequence and carbohydrate ...
They share 57% amino acid sequence homology and have some pharmacological characteristics in common. Both receptors are Gi- ... indicating a high degree of evolutionary conservation of genetic sequence, which suggests that the 5-HT1E receptor has an ...
... have high homology. They have 65% amino acid sequences in common and 92% homology within their kinase domains. ROCKs are ... Mammalian ROCK consists of a kinase domain, a coiled-coil region and a Pleckstrin homology (PH) domain, which reduces the ... ROCK can also be regulated by lipids, in particular arachidonic acid, and protein oligomerization, which induces N-terminal ...
Huhtala ML, Seppälä M, Närvänen A, Palomäki P, Julkunen M, Bohn H (Jun 1987). "Amino acid sequence homology between human ... The N-terminal amino acid sequence of glycodelin is M D I P Q T K Q D L E L P K L A G T W H S M. This sequence can be compared ... Julkunen, M.; Seppala, M.; Janne, O. A. (1988-12-01). "Complete amino acid sequence of human placental protein 14: a ... Julkunen, M.; Seppala, M.; Janne, O. A. (1988-12-01). "Complete amino acid sequence of human placental protein 14: a ...
Some of the proteins participating in T3SS share amino-acid sequence homology to flagellar proteins. Some of the bacteria ... Recognition is done through a secretion signal-a short sequence of amino acids located at the beginning (the N-terminus) of the ... This is done in order to define the function of specific amino acids or regions in a protein. The introduction of a gene or a ... usually within the first 20 amino acids), that the needle complex is able to recognize. Unlike other secretion systems, the ...
... complete amino acid sequence and homologies". Science. 230 (4732): 1385-8. Bibcode:1985Sci...230.1385G. doi:10.1126/science. ... These proteins had a high degree of sequence homology among their amino acid chains, but were determined to be distinct ... A short stretch of acidic amino acids located between the D1 and D2 domains has auto-inhibitory functions. This 'acid box' ... Although these factors possess remarkably similar sequence homology, they do not bind FGFRs and are involved in intracellular ...
... complete amino acid sequence and homologies". Science. 230 (4732): 1385-8. Bibcode:1985Sci...230.1385G. doi:10.1126/science. ... The majority of the substrates of platelet-derived growth factor (PDGF) exhibit similar structures to Src Homology 2 domain. ...
H9401 has 99.679% sequence homology with Ames Ancestor with an amino acid sequence homology of 99.870%. H9401 has a circular ... These include (1) N-glycosylation of N-acetyl-muramic acid, (2) O-acetylation of N-acetylmuramic acid and (3) N-deacetylation ... The sequencing coverage level suggests a molecular ratio of pXO1:pXO2:chromosome as 3:2:1 which is identical to the Ames ... The protein capsule (poly-D-gamma-glutamic acid) is key to evasion of the immune response. It feeds on the heme of blood ...
"Nucleotide and amino acid sequences of human intestinal alkaline phosphatase: close homology to placental alkaline phosphatase ... Berger J, Garattini E, Hua JC, Udenfriend S (February 1987). "Cloning and sequencing of human intestinal alkaline phosphatase ...
... is a 36-amino acid peptide found in the venom of the deathstalker scorpion (Leiurus quinquestriatus) which blocks ... Chlorotoxin has a considerable sequence homology to the class of small insectotoxins. Chlorotoxin is the first reported high- ... It is a peptide consisting of 36 amino acids, with 8 cysteines forming 4 disulfide bonds. ...
... homologies and mechanistic implications of deduced amino acid sequences". Cell. 44 (4): 597-607. doi:10.1016/0092-8674(86)90269 ... 2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci ...
... with high amino acid sequence homology (approximately 90% identity). The sequences of their promoter regions are also highly ... Rao TR, Slobin LI (Mar 1986). "Structure of the amino-terminal end of mammalian elongation factor Tu". Nucleic Acids Research. ... Addition of ethanolamine-phosphoglycerol to specific glutamic acid residues on EF-1 alpha". The Journal of Biological Chemistry ... Nucleic Acids Research. 18 (6): 1513-6. doi:10.1093/nar/18.6.1513. PMC 330519. PMID 2183196. Bec G, Kerjan P, Zha XD, Waller JP ...
Amino acid sequence homology with the other aspartic proteinases, disulfide bond arrangement and site of carbohydrate ... Mucorpepsin (EC 3.4.23.23, Mucor rennin, Mucor aspartic proteinase, Mucor acid proteinase, Mucor acid protease, Mucor miehei ... doi:10.1016/0076-6879(70)19033-1. Ottesen M, Rickert W (1970). "The acid protease of Mucor miehei". Methods Enzymol. 19: 459- ...
This is not to be confused with conservation in amino acid sequences, where the amino acid at a specific position has been ... Sequence homology is the biological homology between DNA, RNA, or protein sequences, defined in terms of shared ancestry in the ... Homology among DNA, RNA, or proteins is typically inferred from their nucleotide or amino acid sequence similarity. Significant ... Alignments of multiple sequences are used to indicate which regions of each sequence are homologous. The term "percent homology ...
IUPAC needed a coding system that represented long sequences of amino acids. This would allow for these sequences to be ... compared to try to find homologies. These codes can consist of either a one-letter code or a three-letter code. These codes ... Amino Acid Codes Archived 5 February 2007 at the Wayback Machine Retrieved 15 April 2010 Amino Acid and Nucleotide Base Codes ... The codes for amino acids (24 amino acids and three special codes) are: The Experimental Thermodynamics books series covers ...
1990). "Complete amino acid sequence and homologies of human erythrocyte membrane protein band 4.2". Proc. Natl. Acad. Sci. U.S ...
The complete amino acid sequence has been defined and it displays 68% sequence homology with charybdotoxin. Iberiotoxin binds ... Iberiotoxin is a 37-amino acid peptide. The formula is C179H274N50O55S7. It is also known as "Potassium channel toxin alpha-KTx ...
The human homolog of the CPT II enzyme shows 82.2% amino acid sequence homology with the rat protein. Significant structural ... This gene is composed of 5 exons that encode a protein 658 amino acids in length. To date, sixty disease-causing mutations ... within the coding sequence of CPT2 have been reported in the literature, of which 41 are thought to result in amino acid ... The majority of the genetic abnormalities in CPT II deficient patients affect amino acid residues somewhat removed from the ...
cDNA cloning and sequence homology with hydroxyamino acid dehydratases from other sources". The Journal of Biological Chemistry ... Human and rat serine dehydratase cDNA are identical except for a 36 amino acid residue stretch. Similarities have also been ... Human SDH shows sequence homology of 27% with the yeast enzyme and 27% with the E. coli enzyme. Overall PLP enzymes exhibit ... homocysteine is an amino acid and metabolite of methionine; increased levels of homocysteine can lead to homocystinuria(see ...
The gene codes for a protein of 683 residues, which lacks a homology to known amino acid sequences. On evidence of ... 2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40-5. doi:10.1038/ ... 2004). "The DNA sequence and analysis of human chromosome 13". Nature. 428 (6982): 522-8. Bibcode:2004Natur.428..522D. doi: ... 2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci ...