... is a form of eukaryotic RNA polymerase II that is recruited to the promoters of protein-coding ... ATP + [DNA-directed RNA polymerase II] <=> ADP + [DNA-directed RNA polymerase II] phosphate : catalyzed by CDK9 EC 2.7.11.23. ... The length of the CTD is essential for RNA polymerase II stability. RNA polymerase II stability has been shown to be regulated ... together with RNA polymerase II, bind to and read the single-stranded DNA gene template. The cluster of RNA polymerase II and ...

This gene encodes the fourth-largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in ... "Analysis of the interaction of the novel RNA polymerase II (pol II) subunit hsRPB4 with its partner hsRPB7 and with pol II". ... "Specific binding of RNA polymerase II to the human immunodeficiency virus trans-activating region RNA is regulated by cellular ... DNA-directed RNA polymerase II subunit RPB4 is an enzyme that in humans is encoded by the POLR2D gene. ...

... is a protein that in humans is encoded by the ELL2 gene. The encoded protein is a ... "Entrez Gene: Elongation factor for RNA polymerase II 2". Retrieved 2018-08-24. Martincic K, Alkan SA, Cheatle A, Borghesi L, ... "Transcription elongation factor ELL2 directs immunoglobulin secretion in plasma cells by stimulating altered RNA processing". ... 235 (2): 123-136. doi:10.1530/JOE-17-0112. PMC 5679084. PMID 28870994. v t e (Articles with short description, Short ...

"RNA polymerase: structural similarities between bacterial RNA polymerase and eukaryotic RNA polymerase II". Journal of ... a single RNA polymerase species transcribes all types of RNA. RNA polymerase "core" from E. coli consists of five subunits: two ... RNA polymerase II synthesizes precursors of mRNAs and most sRNA and microRNAs. RNA polymerase III synthesizes tRNAs, rRNA 5S ... RNA polymerase III synthesizes tRNAs, rRNA 5S and other small RNAs found in the nucleus and cytosol. RNA polymerase IV ...

RNA polymerase RNA polymerase II RNA polymerase III Selective factor 1 Russell, Jackie; Zomerdijk, Joost C B M (2006). "The RNA ... Twelve of its subunits have identical or related counterparts in RNA polymerase II (Pol II) and RNA polymerase III (Pol III). ... the polymerase that only transcribes ribosomal RNA (but not 5S rRNA, which is synthesized by RNA polymerase III), a type of RNA ... The HOT1 sequence includes an RNA polymerase I transcription promoter. In a yeast mutant strain defective in RNA polymerase I ...

... is composed of 12 subunits that are paralogous to RNA polymerase II (Pol II) subunits. Approximately half of ... RNA polymerase V (Pol V), previously known as RNA polymerase IVb, is a multisubunit plant specific RNA polymerase. It is ... Zhou, Ming; Law, Julie A. (2015). "RNA Pol IV and V in gene silencing: Rebel polymerases evolving away from Pol II's rules". ... Pol V transcribes one of the two types of non-coding RNA involved in RdDM. In canonical RdDM, Pol V transcribes a scaffold RNA ...

DNA-directed RNA polymerase] Thus, the two substrates of this enzyme are ATP and DNA-directed RNA polymerase, whereas its two ... "A protein kinase that phosphorylates the C-terminal repeat domain of the largest subunit of RNA polymerase II". Proc. Natl. ... RNA-polymerase]-subunit kinase (EC 2.7.11.23) is an enzyme that catalyzes the chemical reaction ATP + [DNA-directed RNA ... DNA-directed RNA polymerase] phosphotransferase. Other names in common use include CTD kinase, and STK9. Lee JM, Greenleaf AL ( ...

Only four subunits distinguish RNAP IV structure from RNAP II and RNAP V. RNA Polymerase V differs from RNAP II by six subunits ... of the siRNAs produced by RNA Polymerase IV, yet are not required for DNA methylation. There is evidence that RNA Polymerase IV ... RNA polymerase IV (RNAP IV) is an enzyme that synthesizes small interfering RNA (siRNA) in plants, which silence gene ... compositions of the RNA-silencing enzymes Pol IV and Pol V reveal their origins as specialized forms of RNA polymerase II". ...

II. Inhibition of RNA polymerase reaction". Journal of Biochemistry. 62 (4): 424-429. doi:10.1093/oxfordjournals.jbchem.a128685 ... in-vitro antibiotic of gram-positive bacteria, through inhibition of the incorporation of Pi in the RNA. in-vitro anticancer ... Footprinting with (methidiumpropyl-EDTA)iron(II)". Biochemistry. 22 (10): 2373-2377. doi:10.1021/bi00279a011. ISSN 0006-2960. ... drug that inhibits RNA synthesis. Evaluation of male fertility: Chromomycin A3 and protamines compete for the same binding ...

... a cofactor for RNA polymerase II, or by TFIID. When promoters use the SAGA/TATA box complex to recruit RNA polymerase II, they ... Duttke SH (July 2014). "RNA polymerase III accurately initiates transcription from RNA polymerase II promoters in vitro". The ... the TATA box is found at RNA polymerase II promoter regions, although some in vitro studies have demonstrated that RNA ... Gene transcription by RNA polymerase II depends on the regulation of the core promoter by long-range regulatory elements such ...

It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within ... Aso T, Lane WS, Conaway JW, Conaway RC (1995). "Elongin (SIII): a multisubunit regulator of elongation by RNA polymerase II". ... Bradsher JN, Jackson KW, Conaway RC, Conaway JW (1994). "RNA polymerase II transcription factor SIII. I. Identification, ... Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. TCEB2 has been ...

Shilatifard A, Conaway RC, Conaway JW (2003). "The RNA polymerase II elongation complex". Annual Review of Biochemistry. 72: ... Nikolov DB, Burley SK (January 1997). "RNA polymerase II transcription initiation: a structural view". Proceedings of the ... Orphanides G, Lagrange T, Reinberg D (November 1996). "The general transcription factors of RNA polymerase II". Genes & ... "The role of general initiation factors in transcription by RNA polymerase II". Trends in Biochemical Sciences. 21 (9): 327-35. ...

Kelly, WG; Dahmus, ME; Hart, GW (1993-05-15). "RNA Polymerase II Is a Glycoprotein. Modification of the COOH-terminal Domain by ... "Reciprocity between O-GlcNAc and O-phosphate on the carboxyl terminal domain of RNA polymerase II". Biochemistry. 40 (26): 7845 ... RNA Pol II, tau, p53, CaMKIV, p65, β-catenin, and α-synuclein. Positive cooperativity has also been observed between these two ... In contrast with the previous study on PFK1, this study found that elevating OGT or O-GlcNAc upregulated PFK1, though the two ...

It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within ... Garrett KP, Haque D, Conaway RC, Conaway JW (Feb 1995). "A human cDNA encoding the small subunit of RNA polymerase II ... Aso T, Lane WS, Conaway JW, Conaway RC (1995). "Elongin (SIII): a multisubunit regulator of elongation by RNA polymerase II". ... Bradsher JN, Jackson KW, Conaway RC, Conaway JW (1994). "RNA polymerase II transcription factor SIII. I. Identification, ...

... topo IIβ-induced DNA double-strand breaks occur at sites of RNA polymerase II pausing, and appear to be required for efficient ... The pausing of RNA polymerase II at these sites and the controlled release of the pausing is thought to have a regulatory role ... RNA polymerase II frequently has a pausing site that is about 30-60 nucleotides downstream of the transcription start site of a ... Topo IIβ, with other associated enzymes, appears to be important for the release of paused RNA polymerase at highly transcribed ...

001239 Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant ... Smale ST, Kadonaga JT (2003). "The RNA polymerase II core promoter". Annual Review of Biochemistry. 72: 449-479. doi:10.1146/ ... Regulatory subunit of cyclin-dependent kinases that mediates phosphorylation of the large subunit of RNA polymerase II CCNL1 NM ... The database was constructed by mining more than 12000 human and mouse RNA-seq datasets. ATF1 NM_005171 ATF2 NM_001880 ATF4 ...

Some of these include RNA polymerase II transcription factor II B, Myc associated zinc fingers, EGR/nerve growth factor induced ... Liu X, Bushnell DA, Kornberg RD (January 2013). "RNA polymerase II transcription: structure and mechanism". Biochimica et ... 1829 (1): 2-8. doi:10.1016/j.bbagrm.2012.09.003. PMC 4244541. PMID 23000482. Yuan X, Wang X, Bi K, Jiang G (December 2015). " ... 2021 (2). doi:10.2218/gtopdb/F1048/2021.2. ISSN 2633-1020. S2CID 237877056. "SLC66A3 solute carrier family 66 member 3 [Homo ...

Functionally, it binds to RNA Polymerase II. Negative Orientation Nuclear Fragile X Mental Retardation Protein Interacting ... Small nucleolar RNA, H/ACA box 31 (SNORA31) does not have a known function at this time. KIAA1704 has ubiquitous low to ... This is an RNA-binding protein associated with Fragile X. Start sites are antisense to start of KIAA1704. Potassium Channel ... There are two predicted transcriptional start sites for this promoter, shown on the adjacent image. KIAA1704 promoter showed ...

"BRCA1 protein is linked to the RNA polymerase II holoenzyme complex via RNA helicase A". Nat. Genet. 19 (3): 254-6. doi:10.1038 ... BRCA1 was shown to co-purify with the human RNA Polymerase II holoenzyme in HeLa extracts, implying it is a component of the ... Cabart P, Chew HK, Murphy S (July 2004). "BRCA1 cooperates with NUFIP and P-TEFb to activate transcription by RNA polymerase II ... Krum SA, Miranda GA, Lin C, Lane TF (December 2003). "BRCA1 associates with processive RNA polymerase II". J. Biol. Chem. 278 ( ...

Cheung, Alan C.M.; Cramer, Patrick (2012). "A Movie of RNA Polymerase II Transcription". Cell. 149 (7): 1431-1437. doi:10.1016/ ... Cheung, AC; Cramer, Patrick (2012). "A Movie of RNA polymerase II Transcription". Cell. 149 (7): 1431-1437. doi:10.1016/j.cell. ... Plaschka, Clemens; Nozawa, Kayo; Cramer, Patrick (2016). "Mediator Architecture and RNA Polymerase II Interaction". Journal of ... Sainsbury, Sarah; Bernecky, Carrie; Cramer, Patrick (2015). "Structural basis of transcription initiation by RNA polymerase II ...

This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in ... DNA-directed RNA polymerase II subunit RPB1, also known as RPB1, is an enzyme that is encoded by the POLR2A gene in humans. ... "Entrez Gene: POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa". Krum SA, Miranda GA, Lin C, Lane TF (December ... Cho H, Orphanides G, Sun X, Yang XJ, Ogryzko V, Lees E, Nakatani Y, Reinberg D (September 1998). "A human RNA polymerase II ...

... which regulates RNA polymerase II during mRNA transcription. The Mediator complex is required for polymerase II transcription ... MED12, or mediator of RNA polymerase II transcription, subunit 12 homolog of S. cerevisiae, is one of several subunits in the ... Sims, R. J. 3rd; Mandal, S. S.; Reinberg, D. (June 2004). "Recent highlights of RNA-polymerase-II-mediated transcription". ... Individuals from two families diagnosed with LFS and one family with FGS were found to have mutations in UPF3B, confirming that ...

This gene encodes the second largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in ... "Specific binding of RNA polymerase II to the human immunodeficiency virus trans-activating region RNA is regulated by cellular ... "Entrez Gene: POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa". Acker, J; de Graaff M; Cheynel I; Khazak V; ... DNA-directed RNA polymerase II subunit RPB2 is an enzyme that in humans is encoded by the POLR2B gene. ...

Transcription termination of RNA polymerase II transcripts is proposed to occur by a two-stage process. The first stage ... Dye MJ, Proudfoot NJ (2001). "Multiple transcript cleavage precedes polymerase release intermination by RNA polymerase II". ... Dye MJ, Gromak N, Proudfoot NJ (2006). "Exon tethering in transcription by RNA polymerase II". Molecular Cell. 21 (6): 849-859 ... Non-coding RNA, Ribozymes, RNA splicing, All stub articles, Molecular and cellular biology stubs, Chemical reaction stubs, ...

This gene encodes the third largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in ... interactions between two members of the TET family, EWS and hTAFII68, and subunits of TFIID and RNA polymerase II complexes". ... "Specific binding of RNA polymerase II to the human immunodeficiency virus trans-activating region RNA is regulated by cellular ... "Entrez Gene: POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa". De Angelis R, Iezzi S, Bruno T, Corbi N, Di ...

This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The ... "Specific binding of RNA polymerase II to the human immunodeficiency virus trans-activating region RNA is regulated by cellular ... DNA-directed RNA polymerases I, II, and III subunit RPABC5 is a protein that in humans is encoded by the POLR2L gene. ... "Entrez Gene: POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa". Acker J, de Graaff M, Cheynel I, Khazak V, ...

This gene encodes the fifth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in ... and RNA polymerase subunit 5, which contributes to the association between TFIIF and RNA polymerase II". J. Biol. Chem. United ... This subunit is shared by the other two DNA-directed RNA polymerases and is present in two-fold molar excess over the other ... interactions between two members of the TET family, EWS and hTAFII68, and subunits of TFIID and RNA polymerase II complexes". ...

Orphanides G, Lagrange T, Reinberg D (November 1996). "The general transcription factors of RNA polymerase II". Genes & ... "Studies of nematode TFIIE function reveal a link between Ser-5 phosphorylation of RNA polymerase II and the transition from ... IIA with TFIIE and TFIIF in transcription initiation by RNA polymerase II". The Journal of Biological Chemistry. 276 (42): ... of the small subunit of TFIIE regulates the transition from transcription initiation to elongation by RNA polymerase II". ...

This gene encodes the seventh largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA ... interactions between two members of the TET family, EWS and hTAFII68, and subunits of TFIID and RNA polymerase II complexes". ... "Specific binding of RNA polymerase II to the human immunodeficiency virus trans-activating region RNA is regulated by cellular ... "Entrez Gene: POLR2G polymerase (RNA) II (DNA directed) polypeptide G". Bertolotti, A; Melot T; Acker J; Vigneron M; Delattre O ...

RNA polymerase II associated protein 2, also known as RPAP2, is a human gene. Model organisms have been used in the study of ... "Entrez Gene: RNA polymerase II associated protein 2". Retrieved 2011-08-30. "Salmonella infection data for Rpap2". Wellcome ... Twenty five tests were carried out on mutant mice and two significant abnormalities were observed. No homozygous mutant embryos ... 27 (2): 262-74. doi:10.1016/j.molcel.2007.06.027. PMC 4498903. PMID 17643375. Ingham RJ, Colwill K, Howard C, Dettwiler S, Lim ...