Neuropathy, ataxia, and retinitis pigmentosaRetinal regeneration: Retinal regeneration deals with restoring retinal function to vertebrates so impaired.Age-Related Eye Disease Study: The Age-Related Eye Disease Study (AREDS) was a clinical trial sponsored by the National Eye Institute, one of the National Institutes of Health in the United States.A Randomized, Placebo-Controlled, Clinical Trial of High-Dose Supplementation With Vitamins C and E, Beta Carotene, and Zinc for Age-Related Macular Degeneration and Vision Loss.Rhodopsin: Rhodopsin (also known as visual purple) is a light-sensitive receptor protein. It is named after ancient Greek ῥόδον (rhódon) for “rose”, due to its pinkish color, and ὄψις (ópsis) for “sight”.Rod cellWallerian degeneration: Wallerian degeneration is a process that results when a nerve fiber is cut or crushed, in which the part of the axon separated from the neuron's cell body degenerates distal to the injury.Trauma and Wallerian Degeneration, University of California, San Francisco This is also known as anterograde or orthograde degeneration.Gross pathology: Gross pathology refers to macroscopic manifestations of disease in organs, tissues, and body cavities. The term is commonly used by anatomical pathologists to refer to diagnostically useful findings made during the gross examination portion of surgical specimen processing or an autopsy.Grow lightOpsinRon Gallemore: Ron P. Gallemore is a registered ophthalmologist with the American Academy of OphthalmologyThe American Academy of Ophthalmology Dr Ron Gallemore certification involved in research and treatment of diseases of the macula and retina.Scanning laser ophthalmoscopyAcademy of Medical Royal Colleges: The Academy of Medical Royal Colleges has a role to promote, facilitate and where appropriate co-ordinate the work of the Medical Royal Colleges and their Faculties for the benefit of patients and healthcare. The Academy comprises the 21 Medical Royal Colleges and Faculties in the United Kingdom and Ireland, with the Presidents of these organisations meeting regularly to agree direction.Silent mutation: Silent mutations are mutations in DNA that do not significantly alter the phenotype of the organism in which they occur. Silent mutations can occur in non-coding regions (outside of genes or within introns), or they may occur within exons.Degenerative disc diseaseMelanopsin: Melanopsin is a type of photopigment belonging to a larger family of light-sensitive retinal proteins called opsins and encoded by the gene Opn4. Two other opsins in the mammalian retina are both involved in the formation of visual images: rhodopsin and photopsin in the rod and cone photoreceptor cells, respectively.Arthur Biedl: Arthur Biedl (4 October 1869 – 26 August 1933) was an Hungarian pathologist born in what today is Comloşu Mic, Romania.TUNEL assayPurtscher's retinopathy: Purtscher's retinopathy is a disease where part of the eye (retina) is damaged. Usually associated with severe head injuries, it may also occur with other types of trauma, such as long bone fractures, or with several non-traumatic systemic diseases.Blind People's Association: The Blind People’s Association (BPA) is an organisation in India which promotes comprehensive rehabilitation of persons with all categories of disabilities through education, training, employment, community based rehabilitation, integrated education, research, publications, human resource development and other innovative means.UsherLipofuscinFrontotemporal lobar degeneration: Frontotemporal lobar degeneration (FTLD) is a pathological process that occurs in frontotemporal dementia. It is characterized by atrophy in the frontal lobe and temporal lobe of the brain, with sparing of the parietal and occipital lobes.LogMAR chart: A LogMAR chart comprises rows of letters and is used by ophthalmologists and vision scientists to estimate visual acuity. This chart was developed at the National Vision Research Institute of Australia in 1976, and is designed to enable a more accurate estimate of acuity as compared to other charts (e.TransducinCoherence theory: In physics, coherence theory is the study of optical effects arising from partially coherent light and radio sources. Partially coherent sources are sources where the coherence time or coherence length are limited by bandwidth, by thermal noise, or by other effect.RecoverinOpsismodysplasiaPedigree chart: A pedigree chart is a diagram that shows the occurrence and appearance or phenotypes of a particular gene or organism and its ancestors from one generation to the next,pedigree chart Genealogy Glossary - About.com, a part of The New York Times Company.Retina bipolar cell: As a part of the retina, the bipolar cell exists between photoreceptors (rod cells and cone cells) and ganglion cells. They act, directly or indirectly, to transmit signals from the photoreceptors to the ganglion cells.Iridogoniodysgenesis, dominant type: Iridogoniodysgenesis, dominant type (type 1, IRID1) refers to a spectrum of diseases characterized by malformations of the irido-corneal angle of the anterior chamber of the eye. Iridogoniodysgenesis is the result of abnormal migration or terminal induction of neural crest cells.Phenotype microarray: The phenotype microarray approach is a technology for high-throughput phenotyping of cells.Self-complementary adeno-associated virus (scAAV): Self-complementary adeno-associated virus (scAAV) is a viral vector engineered from the naturally occurring adeno-associated virus (AAV) to be used as a tool for gene therapy. Use of recombinant AAV (rAAV) has been successful in clinical trials addressing a variety of diseases.Necrobiology: Necrobiology comprises the life processes associated with morphological, biochemical, and molecular changes which predispose, precede, and accompany cell death, as well as the consequences and tissue response to cell death. The word is derived from the Greek νεκρό meaning "death", βìο meaning "life", and λόγος meaning "the study of".Neuromorphology: Neuromorphology (from Greek νεῦρον, neuron, "nerve"; μορφή, morphé, “form”; -λογία, -logia, “study of”[is the study of nervous system] form, shape, and structure. The study involves looking at a particular part of the nervous system from a [[Molecular biology|molecular and cellular level and connecting it to a physiological and anatomical point of view.Intervertebral disc damage and spaceflight: Astronauts have expressed an increased incidence of back pain during spaceflight and herniated intervertebral discs (IVD) have been diagnosed upon return of Skylab and Shuttle spaceflight participants.Lamellar granule: Lamellar granules (otherwise known as membrane-coating granules (MCGs), lamellar bodies, keratinosomes or Odland bodies) are secretory organelles found in type II pneumocytes and keratinocytes. They are oblong structures, appearing about 300-400 nm in width and 100-150 nm in length in transmission electron microscopy images.Rhodopsin kinase: Rhodopsin kinase (, cone opsin kinase, G-protein-coupled receptor kinase 1, GPCR kinase 1, GRK1, GRK7, opsin kinase, opsin kinase (phosphorylating), rhodopsin kinase (phosphorylating), RK, STK14) is a serine/threonine-specific protein kinase involved in phototransduction. This enzyme catalyses the following chemical reactionBESS domain: In molecular biology, the BESS domain is a protein domain which has been named after the three proteins that originally defined the domain: BEAF (Boundary element associated factor 32), Suvar(3)7 and Stonewall ). The BESS domain is 40 amino acid residues long and is predicted to be composed of three alpha helices, as such it might be related to the myb/SANT HTH domain.Coles PhillipsSmith–Lemli–Opitz syndromeGuiding Eyes for the Blind: Yorktown Heights, New YorkMetachronal rhythm: A metachronal rhythm or metachronal wave refers to wavy movements produced by the sequential action (as opposed to synchronized) of structures such as cilia, segments of worms or legs. These movements produce the appearance of a travelling wave.Vitreous membrane: The vitreous membrane (or hyaloid membrane or vitreous cortex) is a layer of collagen separating the vitreous humour from the rest of the eye. At least two parts have been identified anatomically.Flame tetra: The flame tetra (Hyphessobrycon flammeus), also known as the red tetra or tetra of Rio, is a small freshwater fish of the characin family Characidae. The species was first introduced as aquarium fish in 1920 by C.Membrane protein: Membrane proteins are proteins that interact with biological membranes. They are one of the common types of protein along with soluble globular proteins, fibrous proteins, and disordered proteins.