p75NTR is a neurotrophic factor receptor. Neurotrophic factor receptors bind Neurotrophins including Nerve growth factor, ... "The precursor pro-nerve growth factor is the predominant form of nerve growth factor in brain and is increased in Alzheimer's ... The p75 neurotrophin receptor (p75NTR) was first identified in 1973 as the low-affinity nerve growth factor receptor (LNGFR) ... Buxser S, Puma P, Johnson GL (February 1985). "Properties of the nerve growth factor receptor. Relationship between receptor ...

June 2013). "Dependence receptor UNC5D mediates nerve growth factor depletion-induced neuroblastoma regression". The Journal of ... Neogenin p75NTR Ptch1 CDON PLXND1 RET TrkA TrkC EphA4 c-Met Insulin receptor IR Insulin-like growth factor 1 receptor ALK ( ... Complex formation appears to be a function of ligand-receptor interaction, and dependence receptors appear to exist in at least ... The following is the list of known dependence receptors: Notch3 Kremen1 DCC (Deleted in Colorectal Carcinoma) UNC5 receptors ( ...

Milbrandt J (May 1988). "Nerve growth factor induces a gene homologous to the glucocorticoid receptor gene". Neuron. 1 (3): 183 ... Hiromura M, Suizu F, Narita M, Kinowaki K, Noguchi M (September 2006). "Identification of nerve growth factor-responsive ... Nuclear receptor 4A1 (NR4A1) is a member of the NR4A nuclear receptor family of intracellular transcription factors. NR4A1 is ... mapping and expression of a growth factor inducible gene encoding a putative nuclear hormonal binding receptor". The EMBO ...

There is one other BDNF receptor besides TrkB, called the "LNGFR" (for "low-affinity nerve growth factor receptor"). Unlike ... Tropomyosin receptor kinase B (TrkB), also known as tyrosine receptor kinase B, or BDNF/NT-3 growth factors receptor or ... "trkB encodes a functional receptor for brain-derived neurotrophic factor and neurotrophin-3 but not nerve growth factor". Cell ... "trkB encodes a functional receptor for brain-derived neurotrophic factor and neurotrophin-3 but not nerve growth factor". Cell ...

Bose CK (Aug 2005). "Role of nerve growth factor and FSH receptor in epithelial ovarian cancer". Reproductive Biomedicine ... and other growth factors. The FSH receptor can also activate the extracellular signal-regulated kinases (ERK). In a feedback ... The follicle-stimulating hormone receptor or FSH receptor (FSHR) is a transmembrane receptor that interacts with the follicle- ... The longer the receptor remains active, the more kinases are activated, the more receptors are phosphorylated.[citation needed ...

TrkA is a protein encoded by the NTRK1 gene and has the highest affinity to the binding nerve growth factor (NGF) After NGF is ... The common ligands of trk receptors are neurotrophins, a family of growth factors critical to the functioning of the nervous ... Aloe L, Rocco ML, Bianchi P, Manni L (November 2012). "Nerve growth factor: from the early discoveries to the potential ... TrkB has the highest affinity to the binding of brain-derived neurotrophic factor (BDNF) and NT-4. BDNF is a growth factor that ...

Zakharyan, Roksana; Atshemyan, Sofi; Gevorgyan, Anaida; Boyajyan, Anna (2014). "Nerve growth factor and its receptor in ... as such this receptor is of interest in schizophrenia. Agonists at either constituent receptor may modulate the other receptor ... GluR1 subunit-containing AMPA receptors are Ca2+ permeable while GluR2/3 subunit-positive receptors are nearly impermeable to ... AMPA, the most widely distributed receptor in the brain, is a tetrameric ionotropic receptor; alterations in equilibrium ...

... receptors of neurotrophins like nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) - with high affinity ( ... "Neurosteroid dehydroepiandrosterone interacts with nerve growth factor (NGF) receptors, preventing neuronal apoptosis". PLOS ... Glycine receptor antagonists, Human metabolites, Neurosteroids, NMDA receptor agonists, Pregnane X receptor agonists, Sigma ... DHEA-S has also been found to inhibit the TRPV1 and TRPC5 transient receptor potential channels and to inhibit the P2X receptor ...

... receptors for nerve growth factor (NGF) and other neurotrophins, as well as for DHEA and DHEA sulfate (DHEA-S). BNN-27 has ... "Neurosteroid dehydroepiandrosterone interacts with nerve growth factor (NGF) receptors, preventing neuronal apoptosis". PLOS ... DHEA and DHEA-S bound to these receptors with affinities that were in the low nanomolar range (around 5 nM), although the ... with TrkA receptors, regulating neuronal survival and differentiation". Neuropharmacology. 111: 266-282. doi:10.1016/j. ...

... family of Tyrosine kinases receptors. Nerve growth factor (NGF), the prototypical growth factor, is a protein secreted by a ... DevBio.com - 'Neurotrophin Receptors: The neurotrophin family consists of four members: nerve growth factor (NGF), brain ... "Competitive signaling between TrkA and p75 nerve growth factor receptors determines cell survival". The Journal of Neuroscience ... nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4). The term ...

... receptors for the neurotrophins nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF), as well as for DHEA and ... "Neurosteroid dehydroepiandrosterone interacts with nerve growth factor (NGF) receptors, preventing neuronal apoptosis". PLOS ... DHEA and DHEA-S bound to these receptors with affinities that were in the low nanomolar range (around 5 nM), although the ... DHEA and DHEA-S were identified as important endogenous neurotrophic factors. These findings may explain the positive ...

NGFRAP is a nerve growth factor receptor associated protein. This gene is believed to play a role in the pathogenesis of ...

NTRK1 is a receptor for nerve growth factor (NGF). This protein induces outgrowth of axons and dendrites and promotes the ... novel mutations in the TRKA/NGF receptor gene, clinical findings, and results of nerve conduction studies". Am. J. Med. Genet. ... Skin biopsies show a lack of innervation of the eccrine glands and nerve biopsies show a lack of small myelinated and ... CIPA is caused by a genetic mutation that prevents the formation of nerve cells which are responsible for transmitting signals ...

This family of receptors are all activated by neurotrophins, including NGF (for Nerve Growth Factor), BDNF (for Brain Derived ... Tropomyosin receptor kinase C (TrkC), also known as NT-3 growth factor receptor, neurotrophic tyrosine kinase receptor type 3, ... the IGF-1 receptor, the MuSK protein receptor, the vascular endothelial growth factor (VEGF) receptor, etc. The "substrate" ... "low affinity nerve growth factor receptor"). As opposed to TrkC, the LNGFR plays a somewhat less clear role in NT-3 biology. ...

"Nerve growth factor and tissue repair remodeling: trkA(NGFR) and p75(NTR), two receptors one fate". Cytokine & Growth Factor ... Tropomyosin receptor kinase A (TrkA), also known as high affinity nerve growth factor receptor, neurotrophic tyrosine kinase ... There is one other NGF receptor besides TrkA, called the "LNGFR" (for "Low-affinity nerve growth factor receptor "). As opposed ... make up the Trk receptor family. This family of receptors are all activated by protein nerve growth factors, or neurotrophins. ...

Among these were the discovery of the receptors (TRK) of certain nerve growth factors. (Klein et al., Cell 1991a,b) the proof ... guide the growth direction of nerve cell axons via repulsion. (Henkemeyer et al., Cell 1996; Orioli et al., EMBO Journal 1996; ... Rüdiger Klein's scientific research is focused on the molecular mechanisms which allow nerve cells to communicate. Rüdiger ...

"Entrez Gene: NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1". Kimura MT, Irie S, Shoji-Hoshino S, Mukai J ... NGFRAP1 has been shown to interact with YWHAE and Low affinity nerve growth factor receptor. GRCh38: Ensembl release 89: ... identification of regions that mediate nerve growth factor-induced apoptosis". J. Biol. Chem. 277 (16): 13973-82. doi:10.1074/ ... Tong X, Xie D, Roth W, Reed J, Koeffler HP (2003). "NADE (p75NTR-associated cell death executor) suppresses cellular growth in ...

Taniuchi, M.; Clark, H. B.; Johnson, E. M. (1986). "Induction of nerve growth factor receptor in Schwann cells after axotomy". ... In nerve cells, axonal growth is mediated by nerve growth factor in a haptotactic manner, where the axon of nerve cells grows ... One factor that was initially found to influence haptotaxis is serum spreading factor, which is present in blood serum and ... This information could be used to possibly develop methods to promote nerve regeneration in patients that have nerve damage. ...

"Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271". Nature. 466 (7302): 133-7. Bibcode: ... "Epidermal growth factor receptor expression identifies functionally and molecularly distinct tumor-initiating cells in human ... EMT appears to be controlled by canonical pathways such as WNT and transforming growth factor β. EMT's important feature is the ... Leptin receptor (LEPR) is a type I cytokine receptor for the fat associate hormone leptin, which plays an important role in ...

Klein R, Jing SQ, Nanduri V, O'Rourke E, Barbacid M. The trk proto-oncogene encodes a receptor for nerve growth factor. Cell ... "The TRK proto-oncogene encodes a receptor for nerve growth-factor." (1991). "trkC, a new member of the trk family of tyrosine ... Toll-like Receptor-4 (TLR4) Down-regulates MicroRNA-107, Increasing Macrophage Adhesion via Cyclin-dependent Kinase 6.» J Biol ... Lamballe F, Klein R, Barbacid M. «trkC, a new member of the trk family of tyrosine protein kinases, is a receptor for ...

With the exception of nerve growth factor (NGF), all TNFs are homologous to the archetypal TNF-alpha. In their active form, the ... The tumor necrosis factor receptor superfamily (TNFRSF) is a protein superfamily of cytokine receptors characterized by the ... Hehlgans T, Pfeffer K (2005). "The intriguing biology of the tumour necrosis factor/tumour necrosis factor receptor superfamily ... Tumor+Necrosis+Factor+Receptor at the U.S. National Library of Medicine Medical Subject Headings (MeSH) (Articles with short ...

Nerve+Growth+Factor+Receptors at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Reichardt, L. F. (2006 ... Neurotrophic factor receptors or neurotrophin receptors are a group of growth factor receptors which specifically bind to ... Nerve+Growth+Factor+Receptor+p75 at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Bibel, M.; Hoppe, E ... and NT-3 TrkC binds and is activated only by NT-3 The Low affinity nerve growth factor receptor commonly known as "p75", can ...

"Direct interaction of nerve growth factor receptor, TrkA, with non-receptor tyrosine kinase, c-Abl, through the activation loop ... "Association of the Abl tyrosine kinase with the Trk nerve growth factor receptor". J. Neurosci. Res. 59 (3): 356-64. doi: ... Splice variants of an insulin and growth factor receptor-binding protein with PH and SH2 domains". J. Biol. Chem. 272 (5): 2659 ... van Dijk TB, van Den Akker E, Amelsvoort MP, Mano H, Löwenberg B, von Lindern M (November 2000). "Stem cell factor induces ...

... has been shown to interact with Low affinity nerve growth factor receptor. GRCh38: Ensembl release 89: ENSG00000187601 ... "The p75 neurotrophin receptor interacts with multiple MAGE proteins". J Biol Chem. 277 (51): 49101-4. doi:10.1074/jbc. ...

"Down-regulation of Epidermal Growth Factor Receptors by Nerve Growth Factor in PC12 Cells Is p140trk-, Ras-, and Src-dependent ... "Transcriptional Down-regulation of Epidermal Growth Factor (EGF) Receptors by Nerve Growth Factor (NGF) in PC12 Cells". Journal ... "Transcriptional Down-regulation of Epidermal Growth Factor (EGF) Receptors by Nerve Growth Factor (NGF) in PC12 Cells". Journal ... Lazarovici, Philip; Fink, Donald (August 1999). "Heterologous Upregulation of Nerve Growth Factor-TrkA Receptors in PC12 Cells ...

"Immunocytochemical demonstration of nerve growth factor receptor (NGF-R) in developing human fetal teeth". Anatomy and ... "Immunohistochemical localization of nerve growth factor (NGF) and NGF receptor (NGF-R) in the developing first molar tooth of ... November 1999). "Nerve growth factor (NGF) supports tooth morphogenesis in mouse first branchial arch explants". Developmental ... Once there, the nerves develop around the tooth bud and enter the dental papilla when dentin formation has begun. Nerves never ...

Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75. Nature. 383: 716-9. PMID ... "Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75". Nature. 383 (6602): 716- ... Casaccia published a first-author Nature paper in 1996 showing that nerve growth factor highly specifically promotes the death ... Casaccia and her colleagues later found a critical transcription factor, Yin Yang 1, in the differentiation of OPCs. Casaccia ...

... has been shown to interact with Low affinity nerve growth factor receptor and PKC alpha. GRCh38: Ensembl release 89: ...

... intracellular signaling pathways by binding to diverse targets on fibroblast growth factor and nerve growth factor receptors". ... intracellular signaling pathways by binding to diverse targets on fibroblast growth factor and nerve growth factor receptors". ... "Fibroblast growth factor receptor substrate 2 participates in vascular endothelial growth factor-induced signaling". FASEB J. ... of the mechanisms regulating the differential activation of the mapk cascade by epidermal growth factor and nerve growth factor ...

... has been shown to interact with Ryanodine receptor 2 and Low affinity nerve growth factor receptor. GRCh38: Ensembl ... Chen P, Mayne M, Power C, Nath A (1997). "The Tat protein of HIV-1 induces tumor necrosis factor-alpha production. Implications ... Higuchi H, Yamashita T, Yoshikawa H, Tohyama M (2003). "PKA phosphorylates the p75 receptor and regulates its localization to ... Higuchi, Haruhisa; Yamashita Toshihide; Yoshikawa Hideki; Tohyama Masaya (April 2003). "PKA phosphorylates the p75 receptor and ...

In the presence of nerve growth factor (NGF), TrkA receptors are trafficked to the stimulated side of the growth cone. ... Ephrin's receptor is called Eph and is a receptor tyrosine kinase. Upon activation of the Eph receptor, synaptojanin 1 becomes ... formation because its vesicle pinching role and the possibility of it recycling plasma membrane and growth factor receptor ... During development, receptors are trafficked around the growth cone. This trafficking involves vesicle endocytosis. ...