RDCRN Contact Registry: The Rare Diseases Clinical Research Network (RDCRN) Contact Registry is an international patient contact registry sponsored by the National Institutes of Health. This registry collects basic data (i.TOL101: TOL101, is a murine-monoclonal antibody specific for the human αβ T cell receptor. In 2010 it was an Investigational New Drug under development by Tolera Therapeutics, Inc.LymphangioleiomyomatosisHepatolithiasis: Hepatolithiasis is the presence of gallstones in the biliary ducts of the liver. Treatment is usually surgical.Patient advocacyActinomycosisPulmonary alveolar proteinosisDense artery sign: In medicine, the dense artery sign or hyperdense artery sign is a radiologic sign seen on computer tomography (CT) scans suggestive of early ischemic stroke. In earlier studies of medical imaging in patients with strokes, it was the earliest sign of ischemic stroke in a significant minority of cases.Marketing authorization: Process of reviewing and assessing the dossier to support a medicinal product in view of its marketing (also called licensing, registration, approval, etc.), finalized by granting of a document also called marketing authorization (MA) (equivalent: product license).Neurodegeneration with brain iron accumulation: Neurodegeneration with brain iron accumulation (NBIA) is a group of inherited neurological disorders in which iron accumulates in the basal ganglia, resulting in progressive dystonia, Parkinsonism, spasticity, optic atrophy or retinal degeneration and neuropsychiatric abnormalities.Gross examinationNon-Langerhans cell histiocytosis: Non-Langerhans cell histiocytosis refers to a family of histiocytosis characterized by the absence of Langerhans cells.Pulmonary cystMETeOR: METeOR (Metadata Online Registry), Australia’s repository for national metadata standards for health, housing and community services statistics and information. METeOR is a Metadata registry based on the 2003 version of the ISO/IEC 11179 Information technology - Metadata registries standard.Mouse Phenome Database: The Mouse Phenome Database (MPD) is a web-accessible database of strain characterization data for the laboratory mouse, to facilitate translational research for human health and disease. MPD characterizes phenotype as well as genotype, and provides tools for online analysis.Multifocal fibrosclerosis: Multifocal fibrosclerosis and idiopathic fibrosclerosis are disorders of unknown aetiology, characterised by fibrous lesions (co-)occurring at a variety of sites. Known manifestations include retroperitoneal fibrosis, mediastinal fibrosis and Riedel's thyroiditis.Progressive nodular histiocytoma: Progressive nodular histiocytoma is a cutaneous condition characterized by generalized, discrete yellow papules and nodules with prominent facial involvement.European Union climate and energy package: The European plan on climate change consists of a range of measures adopted by the members of the European Union to fight against climate change. The plan was launched in March 2007, and after months of tough negotiations between the member countries, it was adopted by the European Parliament on December 2008.Pharmaceutical manufacturing: Drug manufacturing is the process of industrial-scale synthesis of pharmaceutical drugs by pharmaceutical companies. The process of drug manufacturing can be broken down into a series of unit operations, such as milling, granulation, coating, tablet pressing, and others.IontocaineEosinophilic ulcer of the oral mucosa: Eosinophilic ulcer of the oral mucosa (also known as "Eosinophilic ulcer of the tongue," "Riga–Fede disease," and "Traumatic eosinophilic granuloma") is a condition characterized by an ulcer with an indurated and elevated border. The lesion might be tender, fast-growing and the patient often not be aware of any trauma in the area.EcallantideList of diseases (E): This is a list of diseases starting with the letter "E".Toronto Western Research Institute: The Toronto Western Research Institute (TWRI) is a non-profit academic medical research institute located in Canada’s largest city, Toronto. The TWRI is one the principal research institutes of the University Health Network of academic teaching hospitals associated with the University of Toronto; the TWRI is also one of the largest research institutes in Canada focussing on human neurological disease from both a basic science and clinical research perspective.Tropheryma whipplei: Tropheryma whipplei, formerly called Tropheryma whippelii, is a bacterium and the causative organism of Whipple's disease and rarely endocarditisSystematic Protein Investigative Research EnvironmentMalformative syndrome: A malformative syndrome (or malformation syndrome) is a recognizable pattern of congenital anomalies that are known or thought to be causally related (VIIth International Congress on Human Genetics).
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