The modeling philosophy of artificial life strongly differs from traditional modeling by studying not only "life-as-we-know-it ... Provide a quantitative model of the interplay between cultural and biological evolution. Establish ethical principles for ... How does life arise from the nonliving? Generate a molecular proto-organism in vitro. Achieve the transition to life in an ... Create a formal framework for synthesizing dynamical hierarchies at all scales. Determine the predictability of evolutionary ...

Such studies provide theoretical and practical frameworks to understand how changes in structure in solution or solid-state ... tests of quantitative models". The Journal of Organic Chemistry. 50 (8): 1216-1224. doi:10.1021/jo00208a014. Emsley, John; ... Because wavefunctions provide the total energy of a given molecular state, guessed molecular geometries can be optimized to ... The study of chemical kinetics is used to determine the rate law for a reaction. The rate law provides a quantitative ...

Still, it would be almost thirty years until the theoretical framework for evolution of complex traits would be widely ... Conventional methods for the detection of quantitative trait loci (QTLs) are based on a comparison of single QTL models with a ... summarized contemporary thinking about the genetic basis of quantitative natural variation: "As genetic studies continued, ever ... QTLs are mapped by identifying which molecular markers (such as SNPs or AFLPs) correlate with an observed trait. This is often ...

Molecular biology is the study of the fundamental chemistry of life, while cellular biology is the examination of the cell; the ... basic principles of physics while Theoretical astronomy is oriented towards the development of computer or analytical models to ... Physics relies heavily on mathematics as the logical framework for formulating and quantifying principles. The study of the ... quantitative experimental testing and observation as the source of verification. Key historical developments in physics include ...

Origin-fixation models appeared in the midst of the molecular revolution, a half-century after the origins of theoretical ... K. McGuigan (2006). "Studying phenotypic evolution using multivariate quantitative genetics". Mol Ecol. 15 (4): 883-96. doi: ... The use of mutation bias in the sense of an asymmetric effect on trait means is not part of the standard framework. When ... they were soon widely applied in neutral models for rates and patterns of molecular evolution; their use in models of molecular ...

Although molecular models of different resolution have been employed, modelling efforts have mainly focused on coarse-grained ... Current residue-level models are only applicable to the study of condensates of intrinsically disordered proteins and nucleic ... Theoretical Biology & Medical Modelling. 4 (15): 15. doi:10.1186/1742-4682-4-15. PMC 1853075. PMID 17430588. Sear RP (May 2007 ... "Physics-driven coarse-grained model for biomolecular phase separation with near-quantitative accuracy". Nature Computational ...

Haussler studied art briefly at the Academy of Art in San Francisco in 1971 and then psychotherapy at Immaculate Heart College ... He is credited with pioneering the use of Hidden Markov models (HMMs), stochastic context-free grammars, and the discriminative ... While pursuing his doctorate in theoretical computer science at the University of Colorado, Haussler became interested in the ... He develops new statistical and algorithmic methods to explore the molecular function and evolution of the human genome, ...

Molecular model for describing polymers Gravity - Attraction of masses and energy Induced gravity - model in which space-time ... There is no theoretical framework quantitatively describing the strength of such decoherence effects, though. The temperature ... Sabine Hossenfelder argues that "one should interpret these studies [comparing dark matter gravitational studies with EG] with ... Another theory of entropy based on geometric considerations (Quantitative Geometrical Thermodynamics, QGT) provides an entropic ...

Korol's work on the evolution of sex and recombination includes developing theoretical models to explain the factors ... Korol's study of incipient sympatric differentiation caused by microsite ecological contrasts is focused on ecological ... Coevolution of DNA-interacting proteins and genome "dialect". Molecular Biology and Evolution 23: 56-64". {{cite journal}}: ... Enhanced efficiency of QTL mapping analysis based on multivariate complexes of quantitative traits. Genetics 157: 1789-1803 ...

Her models are based on experimental data (e.g., calcium imaging, electrophysiology, and behavior experiments) and on new and ... Electrophysiology and imaging studies in many brain regions have since validated the predictions of this phase transition ... Abbott moved from Brandeis to Columbia, and began her Ph.D. with Abbott at the Center for Theoretical Neuroscience. In Rajan's ... Department of Molecular Biology and the Lewis-Sigler Institute for Integrative Genomics, Princeton University for Methods and ...

To structure the study of ecology into a conceptually manageable framework, the biological world is organized into a nested ... Rieseberg, L. (ed.). "Molecular Ecology". Molecular Ecology. Wiley. doi:10.1111/(ISSN)1365-294X. Avise, J. (1994). Molecular ... Some models and empirical studies, however, suggest that disturbances can stabilize the co-evolution and shared niche occupancy ... Holism remains a critical part of the theoretical foundation in contemporary ecological studies. Holism addresses the ...

The objects that he studies are very similar to those by MAPPER, but with sheaf theory as the theoretical foundation. Although ... two in application are on the quantitative analysis of Fullerene stability and quantitative analysis of self-similarity, ... TDA provides a general framework to analyze such data in a manner that is insensitive to the particular metric chosen and ... Biasotti, S.; Giorgi, D.; Spagnuolo, M.; Falcidieno, B. (2008-09-01). "Size functions for comparing 3D models". Pattern ...

This data is then used for training accurate GxE prediction models, mostly involving molecular breeding protocols in ... Environmental epidemiology Epidemiology Exposome Molecular epidemiology Ecophysiology Quantitative Genetics Phenomics "-Omes ... "An integrated framework reinstating the environmental dimension for GWAS and genomic selection in crops". Molecular Plant. 14 ( ... The study of the envirome and its effects is termed enviromics. The term was first coined in the field of psychiatric ...

The book was a scientific study of language, emphasizing quantitative data, and was based on the mathematical model of Claude ... with reinforcement-and using the tools of information and computation to place hypotheses on a sound theoretical framework and ... He also critically viewed the book as not being able to tie its model to details from neurophysiology at a molecular level. Per ... Mathematical models in the social sciences, 1959: Proceedings of the first Stanford symposium, Stanford mathematical studies in ...

Post, Eric S (2019). Time in ecology: a theoretical framework. Monographs in population biology. Vol. 61. Princeton, NJ: ... "a physical approach involving the study of how events occur in a time-space framework". Hägerstrand was inspired in part by ... 5: Constraints". Ecological Modelling. 222 (16): 2945-2972. doi:10.1016/j.ecolmodel.2011.04.019. Peuquet, Donna J (2002). ... Long, Jed A; Nelson, Trisalyn A (2013). "A review of quantitative methods for movement data". International Journal of ...

... natural populations rarely all interbreed as may be assumed in theoretical random models (panmixy). There is usually a ... theory of molecular evolution Panmixia Outbreeding depression Polymorphism Polygenic adaptation Population size Quantitative ... Studies in the fly Drosophila melanogaster suggest that if a mutation changes a protein produced by a gene, this will probably ... and only evolutionary causes that could be expressed in the mathematical framework of population genetics were retained. ...

These constants are known for hydroxyl radical and molecular oxygen. In the absence of such rate constants, quantitative ... Most proteins studied to date are members of very large protein superfamilies, with as many as 600,000 individual members, with ... The issue is specifically addressed in major regulatory frameworks. In Europe, for instance, "nonrelevant" metabolites are ... In combination with transformation product structure models, screening allows a more comprehensive assessment of transformation ...

A recent study based on molecular simulations and compliance constants describes molecular recognition as a phenomenon of ... Grassberger, P. (1986). "Toward a quantitative theory of self-generated complexity". International Journal of Theoretical ... 5. Model the system. 6. Implement the method. Computational complexity theory is the study of the complexity of problems - that ... Design and Validation of an IT Project Complexity Management Framework. KU Leuven University. Available at https://lirias. ...

Turkheimer E, Waldron M (January 2000). "Nonshared environment: a theoretical, methodological, and quantitative review". ... Behavioral genetics refers to the results of adoption studies and twin studies. Adoption Studies: Genetics are not very highly ... The Five Factor Model of personality maps onto the dimensions of childhood temperament. This suggests that individual ... Wrzus C (2021). "Processes of personality development: An update of the TESSERA framework". The Handbook of Personality ...

MicroCT for molecular imaging: Quantitative visualization of complete three-dimensional distributions of gene products in ... He is editor-in-chief of the Vienna Series in Theoretical Biology, a book series devoted to theoretical developments in the ... Studying developmental variation with geometric morphometric image analysis (GMIA). PLoS ONE 9:e115076. doi: 10.1371/journal. ... Biased polyphenism in polydactylous cats carrying a single point mutation: The Hemingway model for digit novelty. Evol Biol 41: ...

The HiTOP model is based on structural studies that span from age 2 to 90 and include samples from many non-Western societies. ... Theoretical models of the causes and consequences of psychiatric problems have traditionally been framed around diagnoses. New ... Jarnecke, Amber M.; South, Susan C. (2017). "Behavior and Molecular Genetics of the Five Factor Model". In Widiger, Thomas A. ( ... A quantitative review of longitudinal studies". Psychological Bulletin. 126 (1): 3-25. doi:10.1037/0033-2909.126.1.3. PMID ...

... and is also considered the father of mathematical biophysics and theoretical biology. He studied theoretical physics at the St ... In USA he worked at first for the Westinghouse Research Labs in Pittsburgh where he focused on the theoretical physics modeling ... In the second half of the 1960s, he introduced the concept of "organismic sets" that provided a unified framework for physics, ... Cold Springs Harbor Symposia on Quantitative Biology.IV: Excitation Phenomena., 1936, p.90. Mathematical Biophysics:Physico- ...

Studies included molecular systems like optical switches, natural and non-natural photosynthetic model systems and membrane ... Method development in theoretical biophysics plays an increasingly important role in the study of macromolecular complexes and ... Eltsov M, Dube N, Yu Z, Pasakarnis L, Haselmann-Weiss U, Brunner D, Frangakis AS (2015). "Quantitative analysis of cytoskeletal ... reversible conformational equilibrium in the function and regulation of an ABC exporter and established a mechanistic framework ...

Atomic, molecular, and optical physics (AMO) is the study of matter-matter and light-matter interactions on the scale of single ... The Big Bang model rests on two theoretical pillars: Albert Einstein's general relativity and the cosmological principle. ... Einstein contributed the framework of special relativity, which replaced notions of absolute time and space with spacetime and ... Physics became a separate science when early modern Europeans used experimental and quantitative methods to discover what are ...

In statistical physics, Monte Carlo molecular modeling is an alternative to computational molecular dynamics, and Monte Carlo ... The systems can be studied in the coarse-grained or ab initio frameworks depending on the desired accuracy. Computer ... Although type I error and power properties of statistics can be calculated for data drawn from classical theoretical ... Monte Carlo methods are widely used in engineering for sensitivity analysis and quantitative probabilistic analysis in process ...

... aspherical pseudoatom data bank for the comparison of molecular electrostatic potentials in structure-activity studies". Acta ... The Independent Atom Model (abbreviated to IAM), upon which the Multipole Model is based, is a method of charge density ... I. Quantum-mechanical and crystallographic framework of the method". Acta Crystallographica Section A. 64 (4): 437-449. Bibcode ... does have quantitative features which are close to many results based on quantum chemical calculations". If the overlap between ...

Regression models are designed to measure variance within data relative to a theoretical model: there is nothing to suggest ... In molecular epidemiology the phenomena studied are on a molecular biology level, including genetics, where biomarkers are ... Proponents of quantitative methods have also increasingly adopted the potential outcomes framework, developed by Donald Rubin, ... Common frameworks for causal inference include the causal pie model (component-cause), Pearl's structural causal model (causal ...

Early models on sensory processing understood within a theoretical framework are credited to Horace Barlow. Somewhat similar to ... Computational neuroscience provides a mathematical framework for studying the mechanisms involved in brain function and allows ... These are the bases for some quantitative modeling of large-scale brain activity. The Computational Representational ... We know from molecular biology that distinct parts of the nervous system release distinct chemical cues, from growth factors to ...

If it is studied from the viewpoint of relational organization then it is defined as semantic entailment in the brain of ... It provides a framework for linking the great diversity of specializations within contemporary neuroscience, including ... With the creation of a standardized integrated database of neuroscience data, lead to statical models that would otherwise not ... Chauvet, Gilbert (1996). Theoretical Systems in Biology: Hierarchal and Functional Integration. Oxford [United Kingdom]: ...

The study of the motion of bodies is an ancient one, making classical mechanics one of the oldest and largest subjects in ... As an example, assume that friction is the only force acting on the particle, and that it may be modeled as a function of the ... The reality of that particular experiment is disputed, but he did carry out quantitative experiments by rolling balls on an ... In particular, he obtained a theoretical explanation of Kepler's laws of motion of the planets. Newton had previously invented ...