PurinePurine nucleotide cycle: The Purine Nucleotide Cycle is a metabolic pathway in which fumarate is generated from aspartate in order to increase the concentration of Krebs cycle intermediates.Salway, J.LodenosinePurine nucleoside phosphorylase deficiencyArabinosyltransferase: In molecular biology, an arabinosyltransferase is a transferase enzyme acting upon arabinose."Reconstitution of functional mycobacterial arabinosyltransferase AftC proteoliposome and assessment of decaprenylphosphorylarabinose analogues as arabinofuranosyl donors.TRNA (adenine57-N1/adenine58-N1)-methyltransferase: TRNA (adenine57-N1/adenine58-N1)-methyltransferase (, TrmI, PabTrmI, AqTrmI, MtTrmI) is an enzyme with system name S-adenosyl-L-methionine:tRNA (adenine57/adenine58-N1)-methyltransferase. This enzyme catalyses the following chemical reactionThioinosinic acidArchaeosine synthase: Archaeosine synthase (, ArcS, TgtA2, MJ1022 (gene), glutamine:preQ0-tRNA amidinotransferase) is an enzyme with system name L-glutamine:7-cyano-7-carbaguanine aminotransferase. This enzyme catalyses the following chemical reactionAmidophosphoribosyltransferase: Amidophosphoribosyltransferase (ATase), also known as glutamine phosphoribosylpyrophosphate amidotransferase (GPAT), is an enzyme responsible for catalyzing the conversion of 5-phosphoribosyl-1-pyrophosphate (PRPP) into 5-phosphoribosyl-1-amine (PRA), using the ammonia group from a glutamine side-chain. This is the committing step in de novo purine synthesis.Nucleotide salvage: A salvage pathway is a pathway in which nucleotides (purine and pyrimidine) are synthesized from intermediates in the degradative pathway for nucleotides.S-methyl-5'-thioinosine phosphorylase: S-methyl-5'-thioinosine phosphorylase (, MTIP, MTI phosphorylase, methylthioinosine phosphorylase) is an enzyme with system name S-methyl-5'-thioinosine:phosphate S-methyl-5-thio-alpha-D-ribosyl-transferase. This enzyme catalyses the following chemical reactionAlpha-D-ribose 1-methylphosphonate 5-triphosphate synthase: Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase () is an enzyme with system name ATP:methylphosphonate 5-triphosphoribosyltransferase. This enzyme catalyses the following chemical reactionNucleoside analogue: Nucleoside analogues are nucleosides which contain a nucleic acid analogue and a sugar. Nucleotide analogs are nucleotides which contain a nucleic acid analogue, a sugar and one to three phosphate groups.Glycineamide ribonucleotideAdenosine receptor: The adenosine receptors (or P1 receptors) are a class of purinergic G protein-coupled receptors with adenosine as endogenous ligand.UDP-4-amino-4-deoxy-L-arabinose formyltransferase: UDP-4-amino-4-deoxy-L-arabinose formyltransferase (, UDP-L-Ara4N formyltransferase, ArnAFT) is an enzyme with system name 10-formyltetrahydrofolate:UDP-4-amino-4-deoxy-beta-L-arabinose N-formyltransferase. This enzyme catalyses the following chemical reactionEtamiphyllineAdenylosuccinateAdenosine deaminase deficiencyPolyoxins: Polyoxins are a group of nucleoside antibiotics composed of heterocyclic moieties containing nitrogen. An example is Polyoxin B.Dihydrofolic acidNucleobase cation symporter-1DeoxyadenosineRibose-phosphate diphosphokinase: Ribose-phosphate diphosphokinase (or phosphoribosyl pyrophosphate synthetase or ribose-phosphate pyrophosphokinase) is an enzyme that converts ribose 5-phosphate into phosphoribosyl pyrophosphate (PRPP). It is classified under .J. Edwin Seegmiller: J(arvis) Edwin Seegmiller, or Jay Seegmiller, (June 22, 1920 - May 31, 2006) was an American physician and biochemical geneticist best known for his role in discovering the biochemical basis of the Lesch-Nyhan syndrome. He was a rheumatologist and a pioneer in research on arthritic diseases and on aging.EnprofyllineMizoribineNTP binding site: An NTP binding site is a type of binding site found in nucleoside monophosphate (NMP) kinases, N can be adenosine or guanosine. A P-loop is one of the structural motifs common for nucleoside triphosphate (NTP) binding sites, it interacts with the bound nucleotide's phosphoryl groups.AzaserineRNTP: A ribonucleoside tri-phosphate (rNTP) is a ribonucleoside with 3 phosphate groups. rNTPs are the building blocks of RNA synthesis as well as the synthesis of primers in DNA replication.Allantoic acidCalcium guanylateATC code M04: ==M04A Antigout preparations==Hubert Chantrenne: Hubert Chantrenne (1918–2007) was a Belgian scientist, and one of the pioneers of molecular biology at the Université Libre de Bruxelles. He elucidated the messenger role played by the ribonucleic acid (RNA) in the synthesis of proteins in ribosome, organelles of the cellular cytoplasm.Energy charge: Energy charge is an index used to measure the energy status of biological cells. It is related to ATP, ADP and AMP concentrations.Phosphoribosyl-N-formylglycineamidePyrazolopyrimidineBurst kinetics: Burst kinetics is a form of enzyme kinetics that refers to an initial high velocity of enzymatic turnover when adding enzyme to substrate. This initial period of high velocity product formation is referred to as the "Burst Phase".Concentrative nucleoside transporter: Human concentrative nucleoside transporters include SLC28A1, SLC28A2 and SLC28A3 proteins. SLC28A2 is a purine-specific Na+-nucleoside cotransporter localised to the bile canalicular membrane.Inhibitor protein: The inhibitor protein (IP) is situated in the mitochondrial matrix and protects the cell against rapid ATP hydrolysis during momentary ischaemia. In oxygen absence, the pH of the matrix drops.Depurination: Depurination is a chemical reaction of purine deoxyribonucleosides, deoxyadenosine and deoxyguanosine, and ribonucleosides, adenosine or guanosine, in which the β-N-glycosidic bond is hydrolytically cleaved releasing a nucleic base, adenine or guanine, respectively. The second product of depurination of deoxyribonucleosides and ribonucleosides is sugar, 2’-deoxyribose and ribose, respectively.XanthinuriaSymmetry element: A symmetry element is a point of reference about which symmetry operations can take place. In particular, symmetry elements can be centers of inversion, axes of rotation and mirror planes.EHNAColes PhillipsIMP dehydrogenaseSurE, survival protein E: In molecular biology, the protein domain surE refers to survival protein E. It was originally found that cells that did not contain this protein, could not survive in the stationary phase, at above normal temperatures, and in high-salt media.PurinosomeNucleic acid structure: Nucleic acid structure refers to the structure of nucleic acids such as DNA and RNA. Chemically speaking, DNA and RNA are very similar.DNA condensation: DNA condensation refers to the process of compacting DNA molecules in vitro or in vivo. Mechanistic details of DNA packing are essential for its functioning in the process of gene regulation in living systems.Specificity constant: In the field of biochemistry, the specificity constant (also called kinetic efficiency or k_{cat}/K_{M}), is a measure of how efficiently an enzyme converts substrates into products. A comparison of specificity constants can also be used as a measure of the preference of an enzyme for different substrates (i.Smoke DZA: New York, New York, United StatesAminohydrolaseDeoxyguanosine diphosphateDeoxyguanosine triphosphateSilent mutation: Silent mutations are mutations in DNA that do not significantly alter the phenotype of the organism in which they occur. Silent mutations can occur in non-coding regions (outside of genes or within introns), or they may occur within exons.List of strains of Escherichia coli: Escherichia coli is a well studied bacterium that was first identified by Theodor Escherich, after whom it was later named.IMPDH/GMPR family: In molecular biology, the IMPDH/GMPR family of enzymes includes IMP dehydrogenase and GMP reductase. These enzymes are involved in purine metabolism.Uridine triphosphateXanthine oxidase inhibitor: A xanthine oxidase inhibitor is any substance that inhibits the activity of xanthine oxidase, an enzyme involved in purine metabolism. In humans, inhibition of xanthine oxidase reduces the production of uric acid, and several medications that inhibit xanthine oxidase are indicated for treatment of hyperuricemia and related medical conditions including gout.Base pair: Base pairs (unit: bp), which form between specific nucleobases (also termed nitrogenous bases), are the building blocks of the DNA double helix and contribute to the folded structure of both DNA and RNA. Dictated by specific hydrogen bonding patterns, Watson-Crick base pairs (guanine-cytosine and adenine-thymine) allow the DNA helix to maintain a regular helical structure that is subtly dependent on its nucleotide sequence.AICA ribonucleotideHardgainer: A hardgainer is an arbitrary label that describes a person who practices bodybuilding but finds it challenging to develop musculature regardless of the amount of effort put in. The opposite of a hardgainer is an easygainer.TophusGlycine (plant): Glycine is a genus in the bean family Fabaceae. The best known species is the soybean (Glycine max).TetrahydromethanopterinVidarabine phosphateEthyl groupReaction coordinateDNA binding site: DNA binding sites are a type of binding site found in DNA where other molecules may bind. DNA binding sites are distinct from other binding sites in that (1) they are part of a DNA sequence (e.Rasburicase