Purine nucleotide cycle: The Purine Nucleotide Cycle is a metabolic pathway in which fumarate is generated from aspartate in order to increase the concentration of Krebs cycle intermediates.Salway, J.PurineNTP binding site: An NTP binding site is a type of binding site found in nucleoside monophosphate (NMP) kinases, N can be adenosine or guanosine. A P-loop is one of the structural motifs common for nucleoside triphosphate (NTP) binding sites, it interacts with the bound nucleotide's phosphoryl groups.LodenosineThioinosinic acidAmidophosphoribosyltransferase: Amidophosphoribosyltransferase (ATase), also known as glutamine phosphoribosylpyrophosphate amidotransferase (GPAT), is an enzyme responsible for catalyzing the conversion of 5-phosphoribosyl-1-pyrophosphate (PRPP) into 5-phosphoribosyl-1-amine (PRA), using the ammonia group from a glutamine side-chain. This is the committing step in de novo purine synthesis.Energy charge: Energy charge is an index used to measure the energy status of biological cells. It is related to ATP, ADP and AMP concentrations.Ribose-phosphate diphosphokinase: Ribose-phosphate diphosphokinase (or phosphoribosyl pyrophosphate synthetase or ribose-phosphate pyrophosphokinase) is an enzyme that converts ribose 5-phosphate into phosphoribosyl pyrophosphate (PRPP). It is classified under .Hardgainer: A hardgainer is an arbitrary label that describes a person who practices bodybuilding but finds it challenging to develop musculature regardless of the amount of effort put in. The opposite of a hardgainer is an easygainer.AminohydrolaseAdenylosuccinatePurine nucleoside phosphorylase deficiencyNucleotide salvage: A salvage pathway is a pathway in which nucleotides (purine and pyrimidine) are synthesized from intermediates in the degradative pathway for nucleotides.RNTP: A ribonucleoside tri-phosphate (rNTP) is a ribonucleoside with 3 phosphate groups. rNTPs are the building blocks of RNA synthesis as well as the synthesis of primers in DNA replication.Coles PhillipsInhibitor protein: The inhibitor protein (IP) is situated in the mitochondrial matrix and protects the cell against rapid ATP hydrolysis during momentary ischaemia. In oxygen absence, the pH of the matrix drops.TRNA (adenine57-N1/adenine58-N1)-methyltransferase: TRNA (adenine57-N1/adenine58-N1)-methyltransferase (, TrmI, PabTrmI, AqTrmI, MtTrmI) is an enzyme with system name S-adenosyl-L-methionine:tRNA (adenine57/adenine58-N1)-methyltransferase. This enzyme catalyses the following chemical reactionS-methyl-5'-thioinosine phosphorylase: S-methyl-5'-thioinosine phosphorylase (, MTIP, MTI phosphorylase, methylthioinosine phosphorylase) is an enzyme with system name S-methyl-5'-thioinosine:phosphate S-methyl-5-thio-alpha-D-ribosyl-transferase. This enzyme catalyses the following chemical reactionDihydrofolic acidArabinosyltransferase: In molecular biology, an arabinosyltransferase is a transferase enzyme acting upon arabinose."Reconstitution of functional mycobacterial arabinosyltransferase AftC proteoliposome and assessment of decaprenylphosphorylarabinose analogues as arabinofuranosyl donors.IMPDH/GMPR family: In molecular biology, the IMPDH/GMPR family of enzymes includes IMP dehydrogenase and GMP reductase. These enzymes are involved in purine metabolism.MizoribineAzaserineCalcium guanylateSymmetry element: A symmetry element is a point of reference about which symmetry operations can take place. In particular, symmetry elements can be centers of inversion, axes of rotation and mirror planes.Protein primary structure: The primary structure of a peptide or protein is the linear sequence of its amino acid structural units, and partly comprises its overall biomolecular structure. By convention, the primary structure of a protein is reported starting from the amino-terminal (N) end to the carboxyl-terminal (C) end.UDP-4-amino-4-deoxy-L-arabinose formyltransferase: UDP-4-amino-4-deoxy-L-arabinose formyltransferase (, UDP-L-Ara4N formyltransferase, ArnAFT) is an enzyme with system name 10-formyltetrahydrofolate:UDP-4-amino-4-deoxy-beta-L-arabinose N-formyltransferase. This enzyme catalyses the following chemical reactionBurst kinetics: Burst kinetics is a form of enzyme kinetics that refers to an initial high velocity of enzymatic turnover when adding enzyme to substrate. This initial period of high velocity product formation is referred to as the "Burst Phase".AICA ribonucleotideGahJ. Edwin Seegmiller: J(arvis) Edwin Seegmiller, or Jay Seegmiller, (June 22, 1920 - May 31, 2006) was an American physician and biochemical geneticist best known for his role in discovering the biochemical basis of the Lesch-Nyhan syndrome. He was a rheumatologist and a pioneer in research on arthritic diseases and on aging.WGAViewer: WGAViewer is a bioinformatics software tool which is designed to visualize, annotate, and help interpret the results generated from a genome wide association study (GWAS). Alongside the P values of association, WGAViewer allows a researcher to visualize and consider other supporting evidence, such as the genomic context of the SNP, linkage disequilibrium (LD) with ungenotyped SNPs, gene expression database, and the evidence from other GWAS projects, when determining the potential importance of an individual SNP.IMP dehydrogenaseAromatic sulfonation: Aromatic sulfonation is an organic reaction in which a hydrogen atom on an arene is replaced by a sulfonic acid functional group in an electrophilic aromatic substitution..PurinosomeList of strains of Escherichia coli: Escherichia coli is a well studied bacterium that was first identified by Theodor Escherich, after whom it was later named.Adenosine receptor: The adenosine receptors (or P1 receptors) are a class of purinergic G protein-coupled receptors with adenosine as endogenous ligand.Ligation-independent cloning: Ligation-independent cloning (LIC) is a form of molecular cloning that is able to be performed without the use of restriction endonucleases or DNA ligase. This allows genes that have restriction sites to be cloned without worry of chopping up the insert.Uridine triphosphateEtamiphyllineAmmonia transporterGlycineamide ribonucleotideSilent mutation: Silent mutations are mutations in DNA that do not significantly alter the phenotype of the organism in which they occur. Silent mutations can occur in non-coding regions (outside of genes or within introns), or they may occur within exons.Adenosine deaminase deficiencyDNA condensation: DNA condensation refers to the process of compacting DNA molecules in vitro or in vivo. Mechanistic details of DNA packing are essential for its functioning in the process of gene regulation in living systems.SurE, survival protein E: In molecular biology, the protein domain surE refers to survival protein E. It was originally found that cells that did not contain this protein, could not survive in the stationary phase, at above normal temperatures, and in high-salt media.SuraminDNA binding site: DNA binding sites are a type of binding site found in DNA where other molecules may bind. DNA binding sites are distinct from other binding sites in that (1) they are part of a DNA sequence (e.GlutamineEnprofyllineNucleic acid structure: Nucleic acid structure refers to the structure of nucleic acids such as DNA and RNA. Chemically speaking, DNA and RNA are very similar.Specificity constant: In the field of biochemistry, the specificity constant (also called kinetic efficiency or k_{cat}/K_{M}), is a measure of how efficiently an enzyme converts substrates into products. A comparison of specificity constants can also be used as a measure of the preference of an enzyme for different substrates (i.Glyceroneogenesis: Glyceroneogenesis is a metabolic pathway which synthesizes glycerol 3-phosphate or triglyceride from precursors other than glucose.Eukaryotic transcription: Eukaryotic transcription is the elaborate process that eukaryotic cells use to copy genetic information stored in DNA into units of RNA replica. Gene transcription occurs in both eukaryotic and prokaryotic cells.Simon–Ehrlich wager: Julian L. Simon and Paul Ehrlich entered in a widely followed scientific wager in 1980, betting on a mutually agreed-upon measure of resource scarcity over the decade leading up to 1990.Cyclic nucleotideCarbamoyl phosphatePhosphotransferase: Phosphotransferases are a category of enzymes (EC number 2.7) that catalyze phosphorylation reactions.ATC code M04: ==M04A Antigout preparations==Stretch-activated ion channel: Stretch-activated or stretch-gated ion channels are ion channels which open their pores in response to mechanical deformation of a neuron's plasma membrane. Also see mechanosensitive ion channels and mechanosensitive channels, with which they may be synonymous.Nucleotide exchange factor: Nucleotide exchange factors (NEFs) are proteins that stimulate the exchange (replacement) of nucleoside diphosphates for nucleoside triphosphates bound to other proteins.Archaeosine synthase: Archaeosine synthase (, ArcS, TgtA2, MJ1022 (gene), glutamine:preQ0-tRNA amidinotransferase) is an enzyme with system name L-glutamine:7-cyano-7-carbaguanine aminotransferase. This enzyme catalyses the following chemical reactionYjdF RNA motifDNA sequencer: A DNA sequencer is a scientific instrument used to automate the DNA sequencing process. Given a sample of DNA, a DNA sequencer is used to determine the order of the four bases: G (guanine), C (cytosine), A (adenine) and T (thymine).Reaction coordinateMitochondrion: The mitochondrion (plural mitochondria) is a double membrane-bound organelle found in most eukaryotic cells. The word mitochondrion comes from the Greek , , i.Proximity ligation assay: Proximity ligation assay (in situ PLA) is a technology that extends the capabilities of traditional immunoassays to include direct detection of proteins, protein interactions and modifications with high specificity and sensitivity. Protein targets can be readily detected and localized with single molecule resolution and objectively quantified in unmodified cells and tissues.Sodium hexametaphosphateGlycine (plant): Glycine is a genus in the bean family Fabaceae. The best known species is the soybean (Glycine max).Nucleoside analogue: Nucleoside analogues are nucleosides which contain a nucleic acid analogue and a sugar. Nucleotide analogs are nucleotides which contain a nucleic acid analogue, a sugar and one to three phosphate groups.Ethyl group