Hz2V110 is homologous to serine/threonine protein kinase (S_TPK). S_TPK catalyzes phosphorylation of serine and threonine ... Edelman AM, Blumenthal DK, Krebs EG (June 1987). "Protein serine/threonine kinases". Annual Review of Biochemistry. 56 (1): 567 ... "Choristoneura fumiferana Granulovirus p74 protein, a highly conserved baculoviral envelope protein". Journal of Biochemistry ... Of the 113 ORFs that are likely to encode proteins, 66 are on the forward strand of DNA, the other 47 on the reverse. All of ...
DNA-dependent protein kinase (DNA-PK) and mammalian target of rapamycin (mTOR). They are protein serine/threonine kinases. The ... Many PI3Ks appear to have a serine/threonine kinase activity in vitro; however, it is unclear whether this has any role in vivo ... Full activation of AKT occurs upon phosphorylation of serine 473 by the TORC2 complex of the mTOR protein kinase. The PI3K/AKT ... "Cannabinoids protect astrocytes from ceramide-induced apoptosis through the phosphatidylinositol 3-kinase/protein kinase B ...
"Serine/threonine protein kinases and apoptosis". Experimental Cell Research. 256 (1): 34-41. doi:10.1006/EXCR.2000.4836. ISSN ...
... a major tyrosine kinase target protein, is a mitogen-activated serine/threonine protein kinase". Proceedings of the National ... RAF kinases are a family of three serine/threonine-specific protein kinases that are related to retroviral oncogenes. The mouse ... "Direct activation of mitogen-activated protein kinase kinase kinase MEKK1 by the Ste20p homologue GCK and the adapter protein ... Roskoski R (August 2010). "RAF protein-serine/threonine kinases: structure and regulation". Biochemical and Biophysical ...
TBK1 (TANK-binding kinase 1) is an enzyme with kinase activity. Specifically, it is a serine / threonine protein kinase. It is ... The Nck adaptor protein binds to a serine/threonine kinase via an SH3 domain". The Journal of Biological Chemistry. 270 (13): ... The Nck adaptor protein binds to a serine/threonine kinase via an SH3 domain". The Journal of Biological Chemistry. 270 (13): ... Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway ...
"Serine/threonine-protein kinase Nek4". Uniprot. Archived from the original on 2011-04-11. "SNW domain-containing protein 1". ... "Proline-serine-threonine phosphatase-interacting protein 1". Uniprot. Archived from the original on 2009-09-25. " ... "Protein BLAST: search protein databases using a protein query". blast.ncbi.nlm.nih.gov. Retrieved 2020-07-31. Koonin EV (August ... The coded protein is 419 amino acids long and weighs 48.3 kDa. As described in the name, the protein contains a leucine-zipper ...
... belongs to the serine/threonine-specific protein kinase family and therefore has the protein kinase domain in positions ... Serine/threonine-protein kinase RIO1 is an enzyme that in humans is encode by the RIOK1 gene. RIOK1 is an atypical protein, ... "Serine/threonine-protein kinase RIO1". Target Report Card. Hinxton, Cambridgeshire, CB10 1SD, UK: EMBL-EBI, Wellcome Genome ... It belongs to the serine/threonine-specific protein kinase family. It has been intensely studied to understand the maturation ...
"Regulation of glycolysis by Raf protein serine/threonine kinases". Advances in Enzyme Regulation. 42: 317-32. doi:10.1016/S0065 ... Gupta V, Bamezai RN (November 2010). "Human pyruvate kinase M2: a multifunctional protein". Protein Science. 19 (11): 2031-44. ... Pyruvate kinase isozymes M1/M2 (PKM1/M2), also known as pyruvate kinase muscle isozyme (PKM), pyruvate kinase type K, cytosolic ... "Use of a novel method to find substrates of protein kinase C delta identifies M2 pyruvate kinase". The International Journal of ...
"Phosphorylation of Smad signaling proteins by receptor serine/threonine kinases". Protein Kinase Protocols. Methods in ... It lacks an intracellular serine/threonine protein kinase domain and hence is a pseudoreceptor. It binds to the type I receptor ... These receptors are serine/threonine kinase receptors. They have a cysteine rich extracellular domain, a transmembrane domain, ... The type II receptor is a serine/threonine receptor kinase, which catalyzes the phosphorylation of the Type I receptor. Each ...
"Human Mob proteins regulate the NDR1 and NDR2 serine-threonine kinases". J. Biol. Chem. 279 (23): 24444-51. doi:10.1074/jbc. ... "HIV-1 incorporates and proteolytically processes human NDR1 and NDR2 serine-threonine kinases". Virology. 331 (1): 181-9. doi: ... The protein encoded by this gene is a cytoplasmic protein that may play a role in neurite outgrowth. This gene may be involved ... Protein NDRG2 is a protein that in humans is encoded by the NDRG2 gene (NMYC downstream-regulated gene 2). This gene is a ...
"Human Mob proteins regulate the NDR1 and NDR2 serine-threonine kinases". J. Biol. Chem. 279 (23): 24444-51. doi:10.1074/jbc. ... The protein encoded by this gene is similar to the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for ... protein kinase by the hMOB1 protein". J. Biol. Chem. 279 (34): 35228-35. doi:10.1074/jbc.M404542200. PMID 15197186. Strausberg ... Mps one binder kinase activator-like 1A, also known as Mob1 homolog 1A, is a protein that in humans is encoded by the MOBKL1A ...
Serine/threonine-protein kinase 38-like is an enzyme that in humans is encoded by the STK38L gene. GRCh38: Ensembl release 89: ... "Human Mob proteins regulate the NDR1 and NDR2 serine-threonine kinases". J. Biol. Chem. 279 (23): 24444-51. doi:10.1074/jbc. ... "Entrez Gene: STK38L serine/threonine kinase 38 like". Nakajima D, Okazaki N, Yamakawa H, et al. (2003). "Construction of ... 2004). "Regulation of NDR2 protein kinase by multi-site phosphorylation and the S100B calcium-binding protein". J. Biol. Chem. ...
They signal through receptor tyrosine kinases and serine/threonine protein kinases. Several other biomolecules that have ... Whereas neurotrophic factors within the neurotrophin family commonly have a protein tyrosine kinase receptor (Trk), ... Most NTFs exert their trophic effects on neurons by signaling through tyrosine kinases, usually a receptor tyrosine kinase. In ... The NT-3 protein is found within the thymus, spleen, intestinal epithelium but its role in the function of each organ is still ...
Serine/threonine-protein kinase Sgk2 is an enzyme that in humans is encoded by the SGK2 gene. This gene encodes a serine/ ... threonine protein kinase. Although this gene product is similar to serum- and glucocorticoid-induced protein kinase (SGK), this ... 2003). "The serine/threonine kinases SGK2 and SGK3 are potent stimulators of the epithelial Na+ channel alpha,beta,gamma-ENaC ... 2003). "K+ channel activation by all three isoforms of serum- and glucocorticoid-dependent protein kinase SGK". Pflügers Arch. ...
This gene encodes a member of the serine/threonine protein kinase family. The encoded protein contains a Cdc42/Rac-binding p21 ... The kinase domain of this protein is most closely related to that of myotonic dystrophy kinase-related ROK. Studies of the ... CDC42 binding protein kinase beta is a protein that in humans is encoded by the CDC42BPB gene. ... "Entrez Gene: CDC42 binding protein kinase beta". Retrieved 2017-05-31. Choi SH, Czifra G, Kedei N, Lewin NE, Lazar J, Pu Y, ...
MAP kinase-interacting serine/threonine-protein kinase 2 is an enzyme that in humans is encoded by the MKNK2 gene. MNK2 has ... "Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2". The EMBO Journal. 16 (8): 1909-1920. ... "Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2". The EMBO Journal. 16 (8): 1909-1920. ... "Entrez Gene: MKNK2 MAP kinase interacting serine/threonine kinase 2". Scheper GC, Parra JL, Wilson M, Van Kollenburg B, ...
"Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2". EMBO J. 16 (8): 1909-20. doi:10.1093/ ... "Mitogen-activated protein kinase kinase 7 is an activator of the c-Jun NH2-terminal kinase". Proc. Natl. Acad. Sci. U.S.A. 94 ( ... The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal- ... The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to ...
MAP kinase-interacting serine/threonine-protein kinase 1 is an enzyme that in humans is encoded by the MKNK1 gene. MKNK1 has ... Waskiewicz AJ, Flynn A, Proud CG, Cooper JA (1997). "Mitogen-activated protein kinases activate the serine/threonine kinases ... "Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2". EMBO J. ENGLAND. 16 (8): 1909-20. doi: ... a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase ...
... s are serine-threonine kinase receptors. Transforming growth factor beta family proteins ... Additionally, both types have a cysteine-rich extracellular domain and a cytoplasmic serine threonine kinase domain. Type 1 ... Bone morphogenetic protein Miyazono K, Kamiya Y, Morikawa M (January 2010). "Bone morphogenetic protein receptors and signal ... There are four bone morphogenetic protein receptors: Bone morphogenetic protein receptor, type 1: ACVR1 BMPR1A BMPR1B Bone ...
Serine/threonine protein kinase MST4, also known as mammalian STE20-like protein kinase 4 (MST-4), is a protein that in humans ... "Entrez Gene: RP6-213H19.1 serine/threonine protein kinase MST4". Goudreault M, D'Ambrosio LM, Kean MJ, Mullin MJ, Larsen BG, ... The protein kinase localizes to the Golgi apparatus and is specifically activated by binding to the Golgi matrix protein GM130 ... which are a subset of the Ste20-like kinases. The encoded protein contains an amino-terminal kinase domain, and a carboxy- ...
Serine-threonine kinase receptor-associated protein is an enzyme that in humans is encoded by the STRAP gene. STRAP has been ... "Entrez Gene: STRAP serine/threonine kinase receptor associated protein". Datta PK, Moses HL (May 2000). "STRAP and Smad7 ... signaling and PDK1 kinase activity by physical interaction between PDK1 and serine-threonine kinase receptor-associated protein ... "NM23-H1 tumor suppressor physically interacts with serine-threonine kinase receptor-associated protein, a transforming growth ...
The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic ... Kawabata M, Chytil A, Moses HL (March 1995). "Cloning of a novel type II serine/threonine kinase receptor through interaction ... The protein encoded by this gene forms a heteromeric complex with type II TGF-β receptors when bound to TGF-β, transducing the ... Liu F, Ventura F, Doody J, Massagué J (July 1995). "Human type II receptor for bone morphogenic proteins (BMPs): extension of ...
Serine/threonine-protein kinase PLK4 also known as polo-like kinase 4 is an enzyme that in humans is encoded by the PLK4 gene. ... PLK4 encodes a member of the polo family of serine/threonine protein kinases. The protein localizes to centrioles-complex ... Overview of all the structural information available in the PDB for UniProt: O00444 (Human Serine/threonine-protein kinase PLK4 ... Overview of all the structural information available in the PDB for UniProt: Q64702 (Mouse Serine/threonine-protein kinase PLK4 ...
The protein encoded by the casein kinase 1 epsilon gene is a serine/threonine protein kinase and a member of the casein kinase ... CK1ε is a serine/threonine protein kinase and is very highly conserved; therefore, this kinase is very similar to other members ... After priming through phosphorylation by the serine/threonine kinase LATS, both casein kinase 1 epsilon and casein kinase 1 ... and inhibits kinase activity. The Casein kinase 1 epsilon protein is part of the mammalian oscillator, a group of proteins that ...
Pom1 is a serine/threonine protein kinase that localizes to the cell tips. It is a partial mechanism for the formation of the ... Cdr2 is a serine/threonine protein kinase mitotic regulator in the fission yeast S. pombe. It is encoded by the P87050 2247 bp ... The N-terminus contains a sequence characteristic of serine/threonine protein kinase activity. The C-terminus, while non- ... The protein is 775 amino acids in length. Cdr2 is a member of the GIN4 family of kinases, which prevent progression of mitosis ...
Sanjo H, Kawai T, Akira S (October 1998). "DRAKs, novel serine/threonine kinases related to death-associated protein kinase ... kinase-related apoptosis-inducing protein kinase family and encodes an autophosphorylated nuclear protein with a protein kinase ... Serine/threonine kinase 17a is a protein that in humans is encoded by the STK17A gene. This gene is a member of the death- ... "Entrez Gene: Serine/threonine kinase 17a". Garagnani P, Marquis J, Delledonne M, Pirazzini C, Marasco E, Kwiatkowska KM, et al ...
PAK proteins, a family of serine/threonine p21-activated kinases, include PAK1, PAK2, PAK3 and PAK4. These proteins serve as ... "The adaptor protein Nck links receptor tyrosine kinases with the serine-threonine kinase Pak1". The Journal of Biological ... Serine/threonine-protein kinase PAK 1 is an enzyme that in humans is encoded by the PAK1 gene. PAK1 is one of six members of ... Manser E, Leung T, Salihuddin H, Zhao ZS, Lim L (January 1994). "A brain serine/threonine protein kinase activated by Cdc42 and ...
RIP kinases (receptor-interacting protein kinases) are a class of serine/threonine protein kinases. In humans, five different ... Portal: Biology \ v t e (EC 2.7.11, Human proteins, Protein kinases, All stub articles, EC 2.7 stubs). ... "Receptor-interacting protein (RIP) kinase family". Cellular & Molecular Immunology. 7 (4): 243-249. doi:10.1038/cmi.2010.10. ... RIP kinases are known: RIPK1 RIPK2 RIPK3 RIPK4 RIPK5 Zhang, Duanwu; Lin, Juan; Han, Jiahuai (July 2010). " ...
The protein encoded by this gene belongs to the serine/threonine protein kinase family. It is the catalytic subunit of the 5'- ... 1996). "Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine 172 as the ... 2001). "Phosphorylation of elongation factor-2 kinase on serine 499 by cAMP-dependent protein kinase induces Ca2+/calmodulin- ... "Stimulation of glucose transport by AMP-activated protein kinase via activation of p38 mitogen-activated protein kinase". J. ...
The protein undergoes phosphorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase. Interactions of this protein ... "A serine/threonine kinase p90rsk1 phosphorylates the anti-proliferative protein Tob". Genes to Cells. 6 (2): 131-8. doi:10.1046 ... "A serine/threonine kinase p90rsk1 phosphorylates the anti-proliferative protein Tob". Genes to Cells. 6 (2): 131-8. doi:10.1046 ... Protein Tob1 is a protein that in humans is encoded by the TOB1 gene. This gene encodes a member of the tob/btg1 family of anti ...