Human prolactin receptors are insensitive to mouse prolactin. Prolactin levels may be checked as part of a sex hormone workup, ... Hyperprolactinaemia Hypothalamic-pituitary-prolactin axis Male lactation Prolactin modulator Prolactin receptor Prolactin- ... Prolactin plays an important role in maternal behavior. It has been shown in rats and sheep that prolactin affects lipid ... When prolactin binds to the receptor, it causes it to dimerize with another prolactin receptor. This results in the activation ...

Prolactin modulator Hypothalamic-pituitary-prolactin axis Brooks CL (August 2012). "Molecular mechanisms of prolactin and its ... form of prolactin which exerts its antagonist effect by competing with prolactin to bind with prolactin receptors; thereby, ... Prolactin Growth hormone Human placental lactogen Placental growth hormone S179D-hPRL Prolactin receptor antagonists such as ... Abramicheva PA, Smirnova OV (April 2019). "Prolactin Receptor Isoforms as the Basis of Tissue-Specific Action of Prolactin in ...

Prolactin inhibitors suppress and prolactin releasers induce the secretion of prolactin, respectively. Prolactin inhibitors are ... A prolactin modulator is a drug which affects the hypothalamic-pituitary-prolactin axis (HPP axis) by modulating the secretion ... When such drugs are used not for the purpose of inducing prolactin secretion, increased prolactin levels may be unwanted, and ... Indirect dopaminergic agents such as levodopa can also suppress prolactin levels. Other prolactin releasers besides D2 receptor ...

Prolactin induced protein (called GCDFP-15 in this context) in breast cyst fluid or breast tissue serves as marker of both ... Prolactin-induced protein has also been used for identification and detection of disseminated breast cancer cells. The PIP gene ... Prolactin-inducible protein also known as gross cystic disease fluid protein 15 (GCDFP-15), extra-parotid glycoprotein (EP-GP ... Murphy LC, Tsuyuki D, Myal Y, Shiu RP (1987). "Isolation and sequencing of a cDNA clone for a prolactin-inducible protein (PIP ...

PrRP stimulates prolactin (PRL) release and regulates the expression of prolactin through binding to the prolactin-releasing ... "Entrez Gene: PRLH prolactin releasing hormonel". Langmead CJ, Szekeres PG, Chambers JK, Ratcliffe SJ, Jones DN, Hirst WD, Price ... 2003). "Expression of prolactin-releasing peptide and its receptor in the human adrenal glands and tumor tissues of ... Prolactin-releasing peptide (PrRP) is a peptide hormone that in humans is encoded by the PRLH gene. ...

Hypothalamic-pituitary-prolactin axis Lin, S. H. (2008). "Prolactin-Releasing Peptide". Orphan G Protein-Coupled Receptors and ... Its secretion is mediated by estrogen from placenta during pregnancy to elevate blood level of prolactin . While many prolactin ... The prolactin-releasing peptide identified in 1998 was a candidate for this function, however as of 2008 it appears its ... Prolactin-releasing hormone, also known as PRLH, is a hypothetical human hormone or hormone releasing factor. Existence of this ...

Hormones that control the secretion of prolactin from the pituitary gland include dopamine ("prolactin-inhibiting factor", or " ... The hypothalamic-pituitary-prolactin axis (HPP axis), also known as the hypothalamic-pituitary-mammary axis or hypothalamic- ... 479-. ISBN 978-0-12-397769-4. v t e (Breastfeeding, Hormones of the hypothalamic-pituitary-prolactin axis, Neuroendocrinology, ... from the lactotrophs of the pituitary gland into the circulation and the subsequent action of prolactin on tissues such as, ...

The prolactin-releasing peptide receptor (PrRPR) also known as G-protein coupled receptor 10 (GPR10) is a protein that in ... "Entrez Gene: PRLHR prolactin releasing hormone receptor". Hinuma S, Onda H, Fujino M (1999). "The quest for novel bioactive ... 2003). "Expression of prolactin-releasing peptide and its receptor in the human adrenal glands and tumor tissues of ... "Prolactin-Releasing Peptide Receptor". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical ...

"Endogenous human prolactin and not exogenous human prolactin induces estrogen receptor α and prolactin receptor expression and ... Both PR and prolactin receptor (PRLR) knockout mice fail to show lobuloalveolar development, and progesterone and prolactin ... Conversely, prolactin levels remain elevated. As estrogen and progesterone block prolactin-induced lactogenesis by suppressing ... In the absence of regular, episodic suckling, which keeps prolactin concentrations high, levels of prolactin will quickly drop ...

... prolactin; ACTH and cortisol, which cause Cushing's disease; TSH, which causes hyperthyroidism; and FSH and LH. Bowel ...

Some tumors secrete more than one hormone, the most common combination being GH and prolactin, which present as unexpected bone ... and prolactin (PRL). Diagnosis of pituitary adenoma can be made, or at least suspected, by a constellation of related symptoms ... or prolactin-secreting (prolactinoma) adenomas that are large (macroadenomas) and often occur in children, adolescents and ... producing pituitary tumors and in some instances these same tumors also secrete prolactin. There are however no isolated ...

"Prolactin". You and Your Hormones. Society for Endocrinology. Retrieved 7 November 2018. "SSTR2 somatostatin receptor 2 [Homo ... prolactin, and growth hormones. Researchers studied the activity of the receptors by conducting an assay with Ligand binding ...

Prolactin has numerous other effects in both sexes.[citation needed] Prolactin cells are acidophilic by hematoxylin & eosin ... A lactotropic cell (also known as prolactin cell, epsilon acidophil, lactotrope, lactotroph, mammatroph, mammotroph) is a cell ... Other regulators include oxytocin and progesterone.[citation needed] Prolactin is involved in the maturation of mammary glands ... If these cells undergo neoplastic transformation, they will give rise to a prolactinoma, a prolactin-secreting pituitary ...

In addition his work with prolactin helped to develop the drug bromocriptine, used for the treatment of infertility. From 1991 ... Friesen, H; Hwang, P (February 1973). "Human Prolactin". Annual Review of Medicine. 24 (1): 251-270. doi:10.1146/annurev.me. ... for the identification of human prolactin." His research on growth hormones in dwarf children helped in developing a therapy ... a distinguished professor emeritus of the University of Manitoba and the discoverer of human prolactin, a hormone which ...

Many cases were reported after use of prolactin elevating medications such as antipsychotics. Elevated prolactin levels have ... Prolactin-lowering medication has also been reported to reduce the risk of recurrence. In cases of drug-induced ... Steroids are known to cause elevation of prolactin levels and increase risk of several conditions such as diabetes, and other ... Shelly, S.; Boaz, M.; Orbach, H. (2012). "Prolactin and autoimmunity". Autoimmunity Reviews. 11 (6-7): A465-A470. doi:10.1016/j ...

Prolactin stimulates lactogenesis. hCG appears to be soporific during pregnancy; levels of hCG correlate with sleep changes ... In the second half of pregnancy, progesterone and prolactin prepare the mammary glands for lactation. Estrogens and ... and during the luteal phase of the menstrual cycle upon which lobuloalveolar structures form under the influence of prolactin. ...

Prolactin levels increased. Prolactin is a hormone that regulates the generation of breast milk. Prolactin elevation is not as ...

Prolactin - Deficiency (childhood). homocysteine - Excess. Megaloblastic anemia (MA) is associated with GSE and is believed to ...

The release of prolactin triggers the cells in the alveoli to make milk. Prolactin also transfers to the breast milk. Some ... prolactin and growth hormone production, are essential. Growth hormone (GH) is structurally very similar to prolactin and ... This stage requires prolactin. Oxytocin is critical for the milk let-down reflex in response to suckling. Galactorrhea is milk ... At birth, prolactin levels remain high, while the delivery of the placenta results in a sudden drop in progesterone, estrogen, ...

... prolactin (PRL; MIM 176760), and thyroid-stimulating hormone (TSH; MIM 188540). See combined pituitary hormone deficiency (CPHD ...

... prolactin-secreting; 600634; AIP Pituitary hormone deficiency, combined, 1; 613038; POU1F1 Pituitary hormone deficiency, ...

... and prolactin (PRL; MIM 176760). PIT1 is also important for regulation of the genes encoding prolactin and thyroid-stimulating ...

The hormone prolactin stimulates production. Crop milk contains both fat and protein, as with mammalian milk, but unlike ...

STAT5 acetylation on lysines at positions 694 and 701 is important for effective STAT dimerization in prolactin signalling. ... "Acetylation modulates prolactin receptor dimerization". Proceedings of the National Academy of Sciences. 107 (45): 19314-19319 ... "Dynamic Regulation of JAK-STAT Signaling Through the Prolactin Receptor Predicted by Computational Modeling". Cellular and ...

... and elevation of prolactin levels. Mirtazapine is reported to have fewer sexual side effects, most likely because it ...

Increased levels of prolactin in the paternal brain has also been correlated with a more positive response to the infant's cry ... Increased prolactin corresponds to different behavioral changes in different species. In some bird species it is shown to ... "Is prolactin the "breastfeeding hormone"? What is it doing in fathers? - fatherhood". fatherhood. 2016-11-11. Retrieved 2017-09 ... An increase in levels of oxytocin, glucocorticoids, estrogen and prolactin occur in the paternal brain. These hormonal changes ...

... and prolactin (HPPTooltip hypothalamic-pituitary-prolactin axis) axes are branches. It is possible for the function of these ... Prolactin releasing hormone (PRH): stimulates PRL secretion · Prolactin inhibiting hormone (dopamine): inhibits PRL secretion ... Anterior pituitary produces prolactin, GH, TSH, ACTH, FSH, LH. 15-20% of corticotroph cells, produce ACTH. The targets are the ... These hormones are prolactin, growth hormone, TSH, adrenocorticotropic hormone, FSH and LH. They are all released by anterior ...

Gooren LJ, Harmsen-Louman W, van Kessel H (February 1985). "Follow-up of prolactin levels in long-term oestrogen-treated male- ... Bunck MC, Debono M, Giltay EJ, Verheijen AT, Diamant M, Gooren LJ (2009). "Autonomous prolactin secretion in two male-to-female ... Asscheman H, Gooren LJ, Assies J, Smits JP, de Slegte R (June 1988). "Prolactin levels and pituitary enlargement in hormone- ... Schiebinger, Rick J.; Chrousos, George P.; Culter, Gordon B.; Loriaux, D. Lynn (1986). "The Effect of Serum Prolactin on Plasma ...

Jordan VC, Lieberman ME (September 1984). "Estrogen-stimulated prolactin synthesis in vitro. Classification of agonist, partial ...

Prolactin influences social bonding in rats. Oxytocin plays a similar role in non-human primates as it does in humans. Grooming ... Kennett, J.E.; McKee, D.T. (2012). "Oxytocin: An emerging regulator of prolactin secretion in the female rat". Journal of ...