Progesterone
Since eggs release progesterone, sperm may use progesterone as a homing signal to swim toward eggs (chemotaxis). As a result, ... Progesterone can be taken by mouth, through the vagina, and by injection into muscle or fat, among other routes. Progesterone ... Progesterone is the most important progestogen in the body. As a potent agonist of the nuclear progesterone receptor (nPR) ( ... A drop in progesterone levels is possibly one step that facilitates the onset of labor. In addition, progesterone inhibits ...
Progesterone receptor
Progesterone antagonists prevent the structural reconfiguration. After progesterone binds to the receptor, restructuring with ... Membrane progesterone receptor Selective progesterone receptor modulator Phytoprogestogen GRCh38: Ensembl release 89: ... Progesterone is necessary to induce activation of the progesterone receptors. When no binding hormone is present the carboxyl ... the physiological effects of progesterone depend completely on the presence of the human progesterone receptor (hPR), a member ...
Progesterone elevation
A progesterone elevation may refer to: Any elevation in progesterone Specifically, a progesterone level above 0.8 ng/ml on the ... as a biomarker in in vitro fertilization This disambiguation page lists articles associated with the title Progesterone ...
Progesterone dioxime
... , or progesterone 3,20-dioxime (P4-3,20-DO), also known as 3,20-di(hydroxyimino)pregn-4-en-3-one, is a ... Progesterone C3 and C20 oxime conjugates have been found to be water-soluble prodrugs of progesterone and pregnane ... List of progestogen esters § Oximes of progesterone derivatives J. Elks (14 November 2014). The Dictionary of Drugs: Chemical ... It is a progestogen oxime - specifically, the C3 and C20 dioxime of the progestogen progesterone. ...
Progesterone test
... may refer to: Quantification of the content of progesterone in a sample Progestin challenge This ... disambiguation page lists articles associated with the title Progesterone test. If an internal link led you here, you may wish ...
Progesterone (medication)
The progesterone ethers quingestrone (progesterone 3-cyclopentyl enol ether) and progesterone 3-acetyl enol ether are among the ... Sublingual progesterone tablets were marketed under the brand names Progesterone Lingusorbs and Progesterone Membrettes by 1951 ... In contrast to oral progesterone, non-oral progesterone-which can achieve much higher progesterone levels-has not been assessed ... In addition, C3 and C20 conjugates of progesterone, such as progesterone carboxymethyloxime (progesterone 3-(O-carboxymethyl) ...
Progesterone carboxymethyloxime
... , or progesterone 3-(O-carboxymethyl)oxime (P4-3-CMO), is a progestin which was never marketed. ... These properties of progesterone are thought to be caused by its low water solubility and high metabolic clearance rate due to ... It is an oral prodrug of progesterone with improved pharmacokinetic properties. The compound was developed in an attempt to ... Basu, Krishnakali; Kildsig, Dane O.; Mitra, Ashim K. (1988). "Synthesis and kinetic stability studies of progesterone ...
Progesterone monooxygenase
In enzymology, a progesterone monooxygenase (EC 1.14.99.4) is an enzyme that catalyzes the chemical reaction progesterone + AH2 ... This enzyme is also called progesterone hydroxylase. Rahm MA, Sih CJ (August 1966). "Mechanisms of steroid oxidation by ... O2 ⇌ {\displaystyle \rightleftharpoons } testosterone acetate + A + H2O The 3 substrates of this enzyme are progesterone, AH2, ... The systematic name of this enzyme class is progesterone,hydrogen-donor:oxygen oxidoreductase (hydroxylating). ...
Progesterone oxime
... , or progesterone monoxime, is an oxime conjugate of progesterone and may refer to: Progesterone 3-oxime (3-( ... Progesterone dioxime Progestogen ester § Progestogen oximes List of progestogen esters § Oximes of progesterone derivatives ... hydroxyimino)pregn-4-en-3-one) Progesterone 20-oxime (20-(hydroxyimino)pregn-4-en-3-one) ... Progesterone (medication) § Derivatives This set index article lists chemical compounds articles associated with the same name ...
Progesterone synthesis inhibitor
... inhibit the conversion of pregnenolone into progesterone Inhibitors of cholesterol synthesis can also reduce progesterone ... A progesterone synthesis inhibitor, or progestogen synthesis inhibitor, is a type of drug which inhibits the enzymatic ... Examples of such agents include the 3β-HSD inhibitors azastene (WIN-17625) and epostane (WIN-32729). Since progesterone is a ... Progesterone synthesis inhibitors have been researched for medical applications including use as contraceptives, abortifacients ...
Pharmacokinetics of progesterone
A progesterone vaginal ring and progesterone intrauterine device are also available as pharmaceutical products. Progesterone is ... or an agonist of the progesterone receptor, the biological target of progestogens like endogenous progesterone. Progesterone ... Progesterone has been evaluated by the intranasal route, in the form of a nasal spray, in one study. Progesterone levels were ... Progesterone levels measured by RIA or LC-MS after a single dose of 100 mg oral or vaginal micronized progesterone in ...
Membrane progesterone receptor
... delta (mPRδ) is a protein that in humans is encoded by the PAQR6 gene. Membrane progesterone ... The discovery of a membrane located progesterone receptor (mPR) unrelated to the classical progesterone receptor (PR) in fish ... like most of the classical functions of progesterone mediated by progesterone receptors PR-A and PR-B, which mediate ... Membrane progesterone receptor gamma (mPRγ) is a protein that in humans is encoded by the PAQR5 gene. A study about the mPRγ ...
Pharmacodynamics of progesterone
A progesterone vaginal ring and progesterone intrauterine device are also available as pharmaceutical products. Progesterone is ... A study of a vaginal progesterone ring that released almost 10 mg/day progesterone and maintained mean progesterone levels of ... In another study, a progesterone vaginal ring that released about 10 mg/day progesterone and produced progesterone levels of ... or an agonist of the progesterone receptor, the biological target of progestogens like endogenous progesterone. Progesterone ...
Autoimmune progesterone dermatitis
... may appear as urticarial papules, deep gyrate lesions, papulovesicular lesions, an ... Its relapsing-remitting pattern in women correspond to the progesterone levels during the menstrual cycle, which spike twice a ... eczematous eruption, or as targetoid lesions.: 82 Autoimmune progesterone dermatitis initially manifests with eye symptoms, e.g ...
Pharmacology of progesterone
... can be divided into: Pharmacodynamics of progesterone Pharmacokinetics of progesterone ... Pharmacokinetics of estradiol This disambiguation page lists articles associated with the title Pharmacology of progesterone. ...
Progesterone receptor A
The progesterone receptor A (PR-A) is one of three known isoforms of the progesterone receptor (PR), the main biological target ... Scarpin KM, Graham JD, Mote PA, Clarke CL (2009). "Progesterone action in human tissues: regulation by progesterone receptor ( ... "Progesterone receptors, their isoforms and progesterone regulated transcription". Mol. Cell. Endocrinol. 357 (1-2): 18-29. doi: ... The other isoforms of the PR include the PR-B and PR-C. Membrane progesterone receptor Jacobsen BM, Horwitz KB (2012). " ...
Progesterone receptor B
The progesterone receptor B (PR-B) is one of three known isoforms of the progesterone receptor (PR), the main biological target ... Scarpin KM, Graham JD, Mote PA, Clarke CL (2009). "Progesterone action in human tissues: regulation by progesterone receptor ( ... "Progesterone receptors, their isoforms and progesterone regulated transcription". Mol. Cell. Endocrinol. 357 (1-2): 18-29. doi: ... The other isoforms of the PR include the PR-A and PR-C. Membrane progesterone receptor Jacobsen BM, Horwitz KB (2012). " ...
Progesterone 5alpha-reductase
In enzymology, a progesterone 5alpha-reductase (EC 1.3.1.22) is an enzyme that catalyzes the chemical reaction 5alpha-pregnan-3 ... Other names in common use include steroid 5-alpha-reductase, and Delta4-steroid 5alpha-reductase (progesterone). Cheng YJ, ... It is an intermediate in the conversion of progesterone to allopregnalone and isopregnanolone, other common forms of ... Cheng YJ, Karavolas HJ (1975). "Properties and subcellular distribution of delta4-steroid (progesterone) 5alpha-reductase in ...
Progesterone 11alpha-monooxygenase
In enzymology, a progesterone 11alpha-monooxygenase (EC 1.14.99.14) is an enzyme that catalyzes the chemical reaction ... The systematic name of this enzyme class is progesterone,hydrogen-donor:oxygen oxidoreductase (11alpha-hydroxylating). This ... V. 11-alpha-hydroxylation of progesterone by cell-free preparations of Aspergillus ochraceus". Biochim. Biophys. Acta. 202 (1 ... H2O The 3 substrates of this enzyme are progesterone, AH2, and O2, whereas its 3 products are 11alpha-hydroxyprogesterone, A, ...
Progesterone receptor C
The progesterone receptor C (PR-C) is one of three known isoforms of the progesterone receptor (PR), the main biological target ... Scarpin KM, Graham JD, Mote PA, Clarke CL (2009). "Progesterone action in human tissues: regulation by progesterone receptor ( ... "Progesterone receptors, their isoforms and progesterone regulated transcription". Mol. Cell. Endocrinol. 357 (1-2): 18-29. doi: ... The other isoforms of the PR include the PR-A and PR-B. Membrane progesterone receptor Jacobsen BM, Horwitz KB (2012). " ...
Progesterone 3-oxime
... (P4-3-O), also known as 3-(hydroxyimino)pregn-4-en-3-one, is a progesterone derivative which was never ... Progesterone C3 and C20 oxime conjugates, like progesterone 3-(O-carboxymethyl)oxime, have been found to be water-soluble ... List of progestogen esters § Oximes of progesterone derivatives Shoppee, C. W.; Lack, Ruth E.; Newman, B. C. (1964). "640. Aza- ... It is a progestogen oxime - specifically, the C3 oxime of the progestogen progesterone. ...
Progesterone vaginal ring
... , also known as progesterone-only vaginal ring, is a form of vaginal ring used for birth control when ... It works by gradually releasing the hormone progesterone. Progesterone vaginal rings have been approved for medical use since ... "Progesterone Vaginal Ring" (PDF). PATH. Archived (PDF) from the original on 5 November 2017. Retrieved 28 December 2016. World ... "Population Council's Progesterone Contraceptive Vaginal Ring Added to WHO 2015 Essential Medicines List and Included in Medical ...
Selective progesterone receptor modulator
A selective progesterone receptor modulator (SPRM) is an agent that acts on the progesterone receptor (PR), the biological ... Various progesterone analogs, known as progestins, were synthesized and in 1981 the first progesterone receptor antagonist was ... Opposed to progesterone antagonists, the mixed agonist-antagonist SPRM, due to their intrinsic progesterone agonistic activity ... Spitz IM, Chwalisz K (Aug 2010). "Progesterone receptor modulators and progesterone antagonists in women's health". Steroids. ...
Progesterone 3-acetyl enol ether
... , also known as progesterone acetate, as well as 3-acetoxypregna-3,5-dien-20-one, is a ... Progesterone 3-acetyl enol ether is closely related to quingestrone, which is also known as progesterone 3-cyclopentyl enol ... The 3-acetyl ether may be cleaved from progesterone 3-acetyl enol ether in vivo and, based on its chemical structure, this may ... In the Clauberg bioassay the 3β-hydroxy-4-pregnen-20-one shows about the same potency as progesterone (34). In regard to the ...
Progesterone devices used in farm animals
Removal of progesterone device produces a surge of GnRH, generating a pulse of LH that induces ovulation. Progesterone ... They work by increasing circulating plasma progesterone levels with the following consequences: Progesterone suppresses the ... Protocol: Progesterone for 9 days. PGF2α injection on days 5-8. Serve on observed oestrus or fixed time once at 56h or twice at ... It has been suggested that this increased level of plasma progesterone is due to optimal contact of the coil with the vaginal ...
Hydroxyprogesterone acetate
"Comparison of progesterone and glucocorticoid receptor binding and stimulation of gene expression by progesterone, 17-alpha ... OHPA is a progestogen and acts as an agonist of the progesterone receptor (PR), both PRA and PRB isoforms (IC50 = 16.8 nM and ... Chemically pure progesterone was the only substance with progestational properties in general use which could be administered ... OHPA is a progestin, or a synthetic progestogen, and hence is an agonist of the progesterone receptor, the biological target of ...
Estrone (medication)
10 mg progesterone. 1 mg folliculine [estrone]. Freed SC, Greenhill JP (1941). "Therapeutic Use of Estrone Suspensions1". The ... In addition, a combined injectable preparation containing estrone (1 mg) and progesterone (10 mg) is available in the form of ... Synergon, a combination of progesterone and oestrone in an injectable form, is marketed to induce withdrawal bleeding in women ... Estradiol/estrone/estriol Estrone/progesterone Estrogenic substances Sweetman SC, ed. (2009). "Sex hormones and their ...
Estradiol benzoate
"Progesterone". Drugs.com. Retrieved 2018-07-31. Toppozada M, Goldsmith A, eds. (1983). Long-acting Contraception (Report). ... Ober KG, Klein I, Weber M (1954). "[The problem of progesterone therapy; experimental studies on the Hooker-Forbes test and ... At the same time, [progesterone] (AGOLUTIN DEPOT, Biotika, amp. 2 ml / 50 mg, cycle day 18 and 25) is administered. Estrogen ... The full endometrial transformation dosage of estradiol benzoate/progesterone in oil solution is 1 to 2 mg estradiol benzoate ...
List of OMIM disorder codes
PRNP Progesterone resistance; 264080; PGR Progressive external ophthalmoplegia with mitochondrial DNA deletions 3; 609283; ...
Ethisterone
... is a progestogen, or an agonist of the progesterone receptors. It has about 44% of the affinity of progesterone for ... anhydro-oxy-progesterone; anhydro-hydroxy-progesterone; and pregneninolone. Inhoffen HH, Hohlweg W (1938). "Neue per os- ... This indicates that it is not metabolized into progesterone. No aromatization of ethisterone has been detected in vivo, and no ... It was the second progestogen to be marketed, following injected progesterone in 1934, and was both the first orally active ...