Platelet lysate: Human Platelet Lysate (or hPL) is a substitute supplement for fetal bovine serum (FBS) in experimental and clinical cell culture. It corresponds to a turbid, light-yellow liquid that is obtained from human blood platelets after freeze/thaw cycle(s).Antiplatelet drug: An antiplatelet drug (antiaggregant) is a member of a class of pharmaceuticals that decrease platelet aggregation and inhibit thrombus formation. They are effective in the arterial circulation, where anticoagulants have little effect.GPVI: Glycoprotein VI (platelet) also known as GPVI is a glycoprotein receptor for collagen which is expressed in platelets. In humans, glycoprotein VI is encoded by the GPVI gene.Direct thrombin inhibitor: Direct thrombin inhibitors (DTIs) are a class of medication that act as anticoagulants (delaying blood clotting) by directly inhibiting the enzyme thrombin (factor II). Some are in clinical use, while others are undergoing clinical development.Extremophile: An extremophile (from Latin meaning "extreme" and Greek () meaning "love") is an organism that thrives in physically or geochemically extreme conditions that are detrimental to most life on Earth. In contrast, organisms that live in more moderate environments may be termed mesophiles or neutrophiles.FibrinogenAspirinCollagenThrombusRistocetin-induced platelet aggregation: The ristocetin-induced platelet aggregation (RIPA) is an ex vivo assay for live platelet function. It measures platelet aggregation with the help of von Willebrand factor (vWF) and exogenous antibiotic ristocetin added in a graded fashion.Apyrase: Apyrase (, ATP-diphosphatase, adenosine diphosphatase, ADPase, ATP diphosphohydrolase) is a calcium-activated plasma membrane-bound enzyme (magnesium can also activate it) () that catalyses the hydrolysis of ATP to yield AMP and inorganic phosphate. Two isoenzymes are found in commercial preparations from S.Von Willebrand factor type C domain: Von Willebrand factor, type C is a protein domain is found in various blood plasma proteins: complement factors B, C2, CR3 and CR4; the integrins (I-domains); collagen types VI, VII, XII and XIV; and other extracellular proteins.P-selectin glycoprotein ligand-1: Selectin P ligand, also known as SELPLG or CD162 (cluster of differentiation 162), is a human gene.Serotonergic: Serotonergic (, ) or serotoninergic (, ) means "pertaining to or affecting serotonin". Serotonin is a neurotransmitter.Coagulation testing: Blood clotting tests are the tests used for diagnostics of the hemostasis system.ProstacyclinGiant platelet disorderHeparin-induced thrombocytopeniaHuman platelet antigen: Human platelet antigens (HPA) are polymorphisms in platelet antigens. These can stimulate production of alloantibodies, (antibodies against other people's antigens) in recipients of transfused platelets from donors with different HPAs.Erythrocyte aggregation: Erythrocyte aggregation is the reversible clumping of these cells under low shear forces or at stasis. Erythrocytes aggregate in a special way, forming rouleaux.Adrenalin O.D.Ticlopidine: Ticlopidine (trade name Ticlid) is an antiplatelet drug in the thienopyridine family which is an adenosine diphosphate (ADP) receptor inhibitor. Research initially showed that it was useful for preventing strokes and coronary stent occlusions.Glanzmann's thrombastheniaFragment antigen-binding: The fragment antigen-binding (Fab fragment) is a region on an antibody that binds to antigens. It is composed of one constant and one variable domain of each of the heavy and the light chain.Arachidonic acidConcentration effect: In the study of inhaled anesthetics, the concentration effect is the increase in the rate that the Fa(alveolar concentration)/Fi(inspired concentration) ratio rises as the alveolar concentration of that gas is increased. In simple terms, the higher the concentration of gas administered, the faster the alveolar concentration of that gas approaches the inspired concentration.New Zealand rabbitCalcium signaling: Calcium ions are important for cellular signalling, as once they enter the cytosol of the cytoplasm they exert allosteric regulatory effects on many enzymes and proteins. Calcium can act in signal transduction resulting from activation of ion channels or as a second messenger caused by indirect signal transduction pathways such as G protein-coupled receptors.Monoclonal antibody therapyHemorheology: Hemorheology, also spelled haemorheology (from the Greek ‘αἷμα, haima "blood" and rheology), or blood rheology, is the study of flow properties of blood and its elements of plasma and cells. Proper tissue perfusion can occur only when blood's rheological properties are within certain levels.Burst kinetics: Burst kinetics is a form of enzyme kinetics that refers to an initial high velocity of enzymatic turnover when adding enzyme to substrate. This initial period of high velocity product formation is referred to as the "Burst Phase".Adenosine diphosphate receptor inhibitor: Adenosine diphosphate (ADP) receptor inhibitor is a class of antiplatelet agents. These drugs inhibit some or all types of adenosine diphosphate receptors (P2Y receptors).RGD motifProximity ligation assay: Proximity ligation assay (in situ PLA) is a technology that extends the capabilities of traditional immunoassays to include direct detection of proteins, protein interactions and modifications with high specificity and sensitivity. Protein targets can be readily detected and localized with single molecule resolution and objectively quantified in unmodified cells and tissues.TerbogrelProtein primary structure: The primary structure of a peptide or protein is the linear sequence of its amino acid structural units, and partly comprises its overall biomolecular structure. By convention, the primary structure of a protein is reported starting from the amino-terminal (N) end to the carboxyl-terminal (C) end.Platelet-poor plasma: Platelet-Poor Plasma (PPP) is blood plasma with very low number of platelets (< 10 X 103/μL). Traditionally, PPP was recommended for use in platelet aggregation studies to both adjust the Platelet-rich plasma concentration, and to serve as a control.Hydrazine sulfatePiscivorin: Piscivorin is a component of snake venom secreted by the Eastern Cottonmouth (Agkistrodon piscivorus piscivorus). It is a member of the cysteine-rich secretory protein (CRISP) family, which blocks voltage-dependent calcium channels.Specific granule: Specific granules are secretory vesicles found exclusively in cells of the immune system called granulocytes.Temporal analysis of products: Temporal Analysis of Products (TAP), (TAP-2), (TAP-3) is an experimental technique for studyingColes PhillipsPlatelet storage pool deficiencySEA Native Peptide LigationHirudinThrombospondin: A:439-489 A:618-665 A:446-494Blood proteins: Plasma proteins, also termed serum proteins or blood proteins, are proteins present in blood plasma. They serve many different functions, including transport of lipids, hormones, vitamins and minerals in the circulatory system and the regulation of acellular activity and functioning of the immune system.Antithrombotic: An antithrombotic agent is a drug that reduces the formation of blood clots (thrombi).http://cancerweb.Drug-induced thrombocytopenic purpura: Drug-induced thrombocytopenic purpura is a skin condition result from a low platelet count due to drug-induced anti-platelet antibodies caused by drugs such as heparin, sulfonamines, digoxin, quinine, and quinidine.Bleeding diathesisScott syndrome: Scott syndrome is a rare congenital bleeding disorder that is due to a defect in a platelet mechanism required for blood coagulation.Weiss HJ.Pulmonary hemorrhageFlow cytometry: In biotechnology, flow cytometry is a laser-based, biophysical technology employed in cell counting, cell sorting, biomarker detection and protein engineering, by suspending cells in a stream of fluid and passing them by an electronic detection apparatus. It allows simultaneous multiparametric analysis of the physical and chemical characteristics of up to thousands of particles per second.RamatrobanBlood cell: A blood cell, also called a hemocyte, hematocyte, or hematopoietic cell, is a cell produced through hematopoiesis and is normally found in blood. In mammals, these fall into three general categories:Cell adhesionGlycoprotein Ib: Glycoprotein Ib (GPIb), also known as CD42,Trimidox: Trimidox is an antibacterial agent that is used in cattle and swine to prevent and treat infections by both Gram-negative and Gram-positive bacteria. The active ingredients in Trimidox are W/V trimethoprim (4%) and W/V sulfadoxine (20%), the rest of the solution is an organic solvent (40 mg of trimethoprim and 200 mg of sulfadoxine in each ml of solution).