Reduced folate carrier family
Molecular Pharmacology. 82 (2): 209-216. doi:10.1124/mol.112.078642. ISSN 1521-0111. PMC 3400841. PMID 22554803. Bukhari, ... folate carrier-mediated folate/antifolate transport through an antiport mechanism with 5-aminoimidazole-4-carboxamide riboside ...
AICA ribonucleotide
Inosine monophosphate synthase Nicotinamide riboside Zarembo, Alan (1 August 2008). "'Exercise pill' could take the work out of ... Clinical Pharmacology & Toxicology. 105 (1): 10-16. doi:10.1111/j.1742-7843.2009.00402.x. PMID 19486332. S2CID 3062525. Zhang, ...
NAD(P)H dehydrogenase, quinone 2
... in the IUPHAR/BPS Guide to Pharmacology Database". IUPHAR/BPS Guide to Pharmacology CITE. 2019 (4). doi:10.2218/gtopdb/F39/ ... Initially in a reductive phase NQO2 binds to reduced dihydronicotinamide riboside (NRH) electron donor, and mediates a hydride ... 1997). "Catalytic properties of NAD(P)H:quinone oxidoreductase-2 (NQO2), a dihydronicotinamide riboside dependent ...
CD38-IN-78c
Pharmacology & Therapeutics. 172: 116-126. doi:10.1016/j.pharmthera.2016.12.002. PMC 5346344. PMID 27939939. v t e (Articles ... in tissues via inhibition of CD38 mediated breakdown of nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN), and ...
Nicotinamide adenine dinucleotide
The enzymes that make and use NAD+ and NADH are important in both pharmacology and the research into future treatments for ... In 2004, Charles Brenner and co-workers uncovered the nicotinamide riboside kinase pathway to NAD+. The non-redox roles of NAD( ... Belenky P, Racette FG, Bogan KL, McClure JM, Smith JS, Brenner C (2007). "Nicotinamide riboside promotes Sir2 silencing and ... Sauve AA (March 2008). "NAD+ and vitamin B3: from metabolism to therapies". The Journal of Pharmacology and Experimental ...
SARM1
Carty M, Bowie AG (March 2019). "SARM: From immune regulator to cell executioner". Biochemical Pharmacology. 161: 52-62. doi: ... and nicotinic acid riboside. Non-endogenous small chemical molecules have also been shown to inhibit SARM1's enzymatic activity ... thus explaining the potent axon protection provided by treating neurons with the NaMN precursor nicotinic acid riboside (NaR) ...
Adenosine kinase
Kornberg A, Pricer WE (December 1951). "Enzymatic phosphorylation of adenosine and 2,6-diaminopurine riboside". The Journal of ... Boison D (February 2008). "Adenosine as a neuromodulator in neurological diseases". Current Opinion in Pharmacology. 8 (1): 2-7 ... Compounds that are substrates for AdK include the N-nucleosides toyocamycin, tubercidin and 6-methylmecaptopurine riboside; the ... The Journal of Pharmacology and Experimental Therapeutics. 296 (2): 501-9. PMID 11160637. Kowaluk EA, Jarvis MF (March 2000). " ...
Equilibrative nucleoside transporter 1
Cancer Chemotherapy and Pharmacology. 45 (4): 273-8. doi:10.1007/s002800050040. PMID 10755314. S2CID 25693616. Sundaram M, Yao ... mercaptopurine riboside] and dilazep for the human equilibrative nucleoside transporter, hENT1". The Biochemical Journal. 380 ( ...
Adenosine A2A receptor
Flow cytometry studies with anti-A2A receptor monoclonal antibodies". Molecular Pharmacology. 55 (3): 614-24. PMID 10051547. ... Zeatin riboside NECA (5′-(N-Ethylcarboxamido)adenosine) binodenoson Cannabidiol ATL-444 Istradefylline (KW-6002) MSX-3 ... European Journal of Pharmacology. 221 (2-3): 243-7. doi:10.1016/0014-2999(92)90708-C. PMID 1426003. Karlsten R, Gordh T, Post C ... British Journal of Pharmacology. 153 Suppl 1 (S1): S184-90. doi:10.1038/sj.bjp.0707674. PMC 2268059. PMID 18246094. Ferré S, ...
Ribavirin
Such 5' imidazole riboside derivatives show antiviral activity with 5' hydrogen or halide, but the larger the substituent, the ... Molecular Pharmacology. 69 (4): 1461-1467. doi:10.1124/mol.105.020057. PMID 16421290. S2CID 8158590. Kentsis A, Topisirovic I, ... Note that two natural products were already known with this imidazole riboside structure: substitution at the 5' carbon with OH ...