PancytopeniaCongenital hypoplastic anemiaPerforin: Perforin-1 is a protein that in humans is encoded by the PRF1 gene and the Prf1 gene in mice.SplenomegalyBone marrow suppression: Bone marrow suppression or myelotoxicity (adjective myelotoxic) or myelosuppression is the decrease in production of cells responsible for providing immunity (leukocytes), carrying oxygen (erythrocytes), and/or those responsible for normal blood clotting (thrombocytes). Bone marrow suppression is a serious side effect of chemotherapy and certain drugs affecting the immune system such as azathioprine.Multicentric reticulohistiocytosis: Multicentric reticulohistiocytosis is a multisystem disease beginning usually around the age of 50 years old, and is twice as common in women.SLC19A2: Thiamine transporter 1, also known as thiamine carrier 1 (TC1) or solute carrier family 19 member 2 (SLC19A2) is a protein that in humans is encoded by the SLC19A2 gene. SLC19A2 is a thiamine transporter.Gross examinationMacrocytosisLymphomaRefractory cytopenia with multilineage dysplasiaBone marrow examination: Bone marrow examination refers to the pathologic analysis of samples of bone marrow obtained by bone marrow biopsy (often called a trephine biopsy) and bone marrow aspiration. Bone marrow examination is used in the diagnosis of a number of conditions, including leukemia, multiple myeloma, lymphoma, anemia, and pancytopenia.Miliary tuberculosisHemoglobinuriaBlood cell: A blood cell, also called a hemocyte, hematocyte, or hematopoietic cell, is a cell produced through hematopoiesis and is normally found in blood. In mammals, these fall into three general categories: