TroloxMitochondrial ROS: Mitochondrial ROS (mtROS or mROS) are reactive oxygen species (ROS) that are produced by mitochondria. Generation of mitochondrial ROS mainly takes place at the electron transport chain located on the inner mitochondrial membrane during the process of oxidative phosphorylation (OXPHOS).Vaporized hydrogen peroxide: Vaporized hydrogen peroxide — also known as hydrogen peroxide vapor, HPV, and by the trademarked name VHP — is a vapor form of hydrogen peroxide (H2O2) with applications as a low-temperature antimicrobial vapor used to decontaminate enclosed and sealed areas such as laboratory workstations, isolation and pass-through rooms, and even aircraft interiors.Lipid peroxidationSuperoxide dismutase: Superoxide dismutase (SOD, ) is an enzyme that alternately catalyzes the dismutation (or partitioning) of the superoxide (O2−) radical into either ordinary molecular oxygen (O2) or hydrogen peroxide (H2O2). Superoxide is produced as a by-product of oxygen metabolism and, if not regulated, causes many types of cell damage.MalondialdehydeCatalase: Catalase is a common enzyme found in nearly all living organisms exposed to oxygen (such as bacteria, plants, and animals). It catalyzes the decomposition of hydrogen peroxide to water and oxygen.Thiobarbituric acidTable of standard reduction potentials for half-reactions important in biochemistry: The values below are standard reduction potentials for half-reactions measured at 25°C, 1 atmosphere and a pH of 7 in aqueous solution.Glutathione peroxidaseParaquat murders: The paraquat murders were a series of indiscriminate poisonings carried out in Japan in 1985. Police were unable to gather any evidence about the murders other than they were caused by a poisoned beverage that was left inside or around vending machines.Deoxyguanosine diphosphateFatty aldehyde: A fatty aldehyde is an aldehyde with a "fatty" aliphatic carbon chain attached that is typically eight carbon or more in length. In contrast, phenolic aldehydes are aromatic.List of Renault engines: Engines used by French automaker Renault SA have historically been referenced in technical specifications along two distinct systems:Mitochondrion: The mitochondrion (plural mitochondria) is a double membrane-bound organelle found in most eukaryotic cells. The word mitochondrion comes from the Greek , , i.Ascorbic acidTetratricopeptide: B:89-122 A:522-555 B:228-261Isoprostane: The isoprostanes are prostaglandin-like compounds formed in vivo from the free radical-catalyzed peroxidationPotassium superoxideBiomarkers of aging: Biomarkers of aging are biomarkers that better predict functional capacity at a later age than chronological age. Stated another way, biomarkers of aging would give the true "biological age", which may be different from the chronological age.ACES (nutritional supplement): Antioxidant supplements with varying amounts of carotene(s) for (pro) vitamin A, vitamin C, vitamin E and Selenium are known by the acronym, ACES. The commercial ACES formulas are a first generation, high potency, combined antioxidant that vary in component concentrations, specific components or source, and their ratio according to manufacturer and are available as both tablet and capsule.Gross pathology: Gross pathology refers to macroscopic manifestations of disease in organs, tissues, and body cavities. The term is commonly used by anatomical pathologists to refer to diagnostically useful findings made during the gross examination portion of surgical specimen processing or an autopsy.No Mend No RepairPeroxiredoxin: Peroxiredoxins (Prxs, ; HGNC root symbol PRDX) are a ubiquitous family of antioxidant enzymes that also control cytokine-induced peroxide levels and thereby mediate signal transduction in mammalian cells. The family members in humans are PRDX1, PRDX2, PRDX3, PRDX4, PRDX5, and PRDX6.G2-M DNA damage checkpoint: The G2-M DNA damage checkpoint is an important cell cycle checkpoint in eukaryotic organisms ranging from yeast to mammals. This checkpoint ensures that cells don't initiate mitosis before they have a chance to repair damaged DNA after replication.Inflammation: Inflammation (Latin, [is part of the complex biological response of body tissues to harmful stimuli, such as pathogen]s, damaged cells, or irritants.Free-radical reaction: A free-radical reaction is any chemical reaction involving free radicals. This reaction type is abundant in organic reactions.AdipamideFerredoxin-thioredoxin reductase: Ferredoxin-thioredoxin reductase , systematic name ferredoxin:thioredoxin disulfide oxidoreductase, is a [4Fe-4S] protein that plays an important role in the ferredoxin/thioredoxin regulatory chain. It catalyzes the following reaction:
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Xylaria hypoxylon: Xylaria hypoxylon is a species of fungus in the genus Xylaria. It is known by a variety of common names, such as the candlestick fungus, the candlesnuff fungus, carbon antlers, or the stag's horn fungus.Cytoprotection: Cytoprotection is a process by which chemical compounds provide protection to cells against harmful agents.Necrobiology: Necrobiology comprises the life processes associated with morphological, biochemical, and molecular changes which predispose, precede, and accompany cell death, as well as the consequences and tissue response to cell death. The word is derived from the Greek νεκρό meaning "death", βìο meaning "life", and λόγος meaning "the study of".Liver sinusoid: A liver sinusoid is a type of sinusoidal blood vessel (with fenestrated, discontinuous endothelium) that serves as a location for the oxygen-rich blood from the hepatic artery and the nutrient-rich blood from the portal vein.SIU SOM Histology GIOrganic peroxidePerchloromethyl mercaptanConcentration effect: In the study of inhaled anesthetics, the concentration effect is the increase in the rate that the Fa(alveolar concentration)/Fi(inspired concentration) ratio rises as the alveolar concentration of that gas is increased. In simple terms, the higher the concentration of gas administered, the faster the alveolar concentration of that gas approaches the inspired concentration.Temporal analysis of products: Temporal Analysis of Products (TAP), (TAP-2), (TAP-3) is an experimental technique for studyingNitrotyrosinePhytomedicineIron stress repressed RNA: Iron stress repressed RNA (IsrR) is a cis-encoded antisense RNA which regulates the expression of the photosynthetic protein isiA. IsiA expression is activated by the Ferric uptake regulator protein (Fur) under iron stress conditions.Mature messenger RNA: Mature messenger RNA, often abbreviated as mature mRNA is a eukaryotic RNA transcript that has been spliced and processed and is ready for translation in the course of protein synthesis. Unlike the eukaryotic RNA immediately after transcription known as precursor messenger RNA, it consists exclusively of exons, with all introns removed.Endothelial activation: Endothelial activation is a proinflammatory and procoagulant state of the endothelial cells lining the lumen of blood vessels. It is most characterized by an increase in interactions with white blood cells (leukocytes), and it is associated with the early states of atherosclerosis and sepsis, among others.Lipoate—protein ligase: Lipoate—protein ligase (, LplA, lipoate protein ligase, lipoate-protein ligase A, LPL, LPL-B) is an enzyme with system name ATP:lipoate adenylyltransferase. This enzyme catalyses the following chemical reactionGlutathioneXanthine oxidase inhibitor: A xanthine oxidase inhibitor is any substance that inhibits the activity of xanthine oxidase, an enzyme involved in purine metabolism. In humans, inhibition of xanthine oxidase reduces the production of uric acid, and several medications that inhibit xanthine oxidase are indicated for treatment of hyperuricemia and related medical conditions including gout.PhenacylArteriovenous oxygen difference: The arteriovenous oxygen difference, or a-vO2 diff, is the difference in the oxygen content of the blood between the arterial blood and the venous blood. It is an indication of how much oxygen is removed from the blood in capillaries as the blood circulates in the body.Diapolycopene oxygenase: Diapolycopene oxygenase (, crtP) is an enzyme with system name 4,4'-diapolycopene,AH2:oxygen oxidoreductase (4,4'-hydroxylating). This enzyme catalyses the following chemical reactionDyP-type peroxidase family: In molecular biology, the DyP-type peroxidase family is a family of haem peroxidase enzymes.Site-directed spin labeling: Site-directed spin labeling (SDSL) is a technique for investigating the structure and local dynamics of proteins using electron spin resonance. The theory of SDSL is based on the specific reaction of spin labels with amino acids.Maximum life span: Maximum life span is a measure of the maximum amount of time one or more members of a population has been observed to survive between birth and death. The term can also denote an estimate of the maximum amount of time that a member of a given species could survive between life and death, provided circumstances that are optimal to their longevity.Kidney: The kidneys are bean-shaped organs that serve several essential regulatory roles in vertebrates. They remove excess organic molecules from the blood, and it is by this action that their best-known function is performed: the removal of waste products of metabolism.Bacterial glutathione transferase: Bacterial glutathione transferases (GSTs; EC 2.5.Silent mutation: Silent mutations are mutations in DNA that do not significantly alter the phenotype of the organism in which they occur. Silent mutations can occur in non-coding regions (outside of genes or within introns), or they may occur within exons.Matrix model: == Mathematics and physics ==Glucose-methanol-choline oxidoreductase family: In molecular biology, the glucose-methanol-choline oxidoreductase family (GMC oxidoreductase) is a family of enzymes with oxidoreductase activity.AconitaseCaspaseNeuroprotection: Neuroprotection refers to the relative preservation of neuronal structure and/or function. In the case of an ongoing insult (a neurodegenerative insult) the relative preservation of neuronal integrity implies a reduction in the rate of neuronal loss over time, which can be expressed as a differential equation.Myocytolysis: Myocytolysis refers to a degenerative change (often reversible) that occurs to myocytes upon myocardial strain. This phenomenon tends to occur when neighboring cardiac muscle loses its ability to contract (i.Motexafin gadoliniumDietary Supplements (database): The PubMed Dietary Supplement Subset (PMDSS) is a joint project between the National Institutes of Health (NIH) National Library of Medicine (NLM) and the NIH Office of Dietary Supplements (ODS). PMDSS is designed to help people search for academic journal articles related to dietary supplement literature.Gene signature: A gene signature is a group of genes in a cell whose combined expression patternItadani H, Mizuarai S, Kotani H. Can systems biology understand pathway activation?