SaPI: SaPIs (Staphylococcus aureus or superantigen pathogenicity islands) are a family of mobile genetic elements resident in the genome of some strains of Staphylococcus aureus. Much like bacteriophages, SaPIs can be transferred to uninfected cells and integrate into the host chromosome.Staphylococcus cohnii: Staphylococcus cohnii is a Gram positive, coagulase-negative member of the bacterial genus Staphylococcus consisting of clustered cocci. The species commonly lives on human skin; clinical isolates have shown high levels of antibiotic resistance.SCCmec: SCCmec, or staphylococcal cassette chromosome mec, is a mobile genetic element of Staphylococcus bacterial species. This genetic sequence includes the mecA gene coding for resistance to the antibiotic methicillin and is the only known way for Staphylococcus strains to spread the gene in the wild by horizontal gene transfer.Extended-spectrum penicillin: The extended-spectrum penicillins are a group of antibiotics that have the widest antibacterial spectrum of all penicillins.Comprehensive Pharmacy Review, Leon Shargel, 6th edition, p917 Some sources identify them with antipseudomonal penicillins,Elsevier's Integrated Review Pharmacology, By Mark Kester, Kelly Dowhower Karpa, Kent E.CoagulaseNafcillinBacitracinCefoxitinMeticillinSt. Columcille's Hospital: St. Columcille's Hospital, Loughlinstown is a publichttp://www.Latex fixation test: The latex agglutination method is used clinically in the identification and typing of many important microorganisms. These tests are based on and utilize the patient's antigen-antibody immune response.VancomycinStaphylococcus epidermidis: Staphylococcus epidermidis is a Gram-positive bacterium, and one of over 40 species belonging to the genus Staphylococcus. It is part of the normal human flora, typically the skin flora, and less commonly the mucosal flora.Ferric uptake regulator family: In molecular biology, the ferric uptake regulator (FUR) family of proteins includes metal ion uptake regulator proteins. These are responsible for controlling the intracellular concentration of iron in many bacteria.OST4: In molecular biology, OST4 (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4) is a subunit of the oligosaccharyltransferase complex.Staphylococcus haemolyticusCloxacillinResistome: The resistome is a proposed expression by Gerard D. Wright for the collection of all the antibiotic resistance genes and their precursors in both pathogenic and non-pathogenic bacteria.Trypticase soy agar: Trypticase soy agar or Tryptone Soya Agar (TSA) and trypticase soy broth or Tryptone Soya Broth (TSB) with agar are growth media for the culturing of bacteria. They are general-purpose media, providing enough nutrients to allow for a wide variety of microorganisms to grow.GentamicinEagle's minimal essential medium: Eagle's minimal essential medium (EMEM) is a cell culture medium developed by Harry Eagle that can be used to maintain cells in tissue culture.Infective endocarditisStaphylococcus saprophyticus: Staphylococcus saprophyticus is a Gram-positive, coagulase-negative bacterium belonging to the Staphylococcus genus. S.AmpicillinAnaerobacter: Anaerobacter are a genus of Gram-positive bacteria related to Clostridium. They are anaerobic chemotrophs and are unusual spore-formers as they produce more than one spore per bacterial cell (up to five spores).Discovery and development of cephalosporins: Cephalosporins are a broad class of bactericidal antibiotics that include the β-lactam ring and share a structural similarity and mechanism of action with other β-lactam antibiotics (e.g.Vancomycin-resistant Staphylococcus aureus: Vancomycin-resistant Staphylococcus aureus refers to strains of Staphylococcus aureus that have become resistant to the glycopeptide antibiotic vancomycin.Beta-lactamaseMannitol motility medium: Mannitol motility medium is a bacterial growth medium used to detect the ability of bacteria to ferment mannite and produce nitrogen gas; and to indicate the motility of the organism.Skin and skin structure infection: A skin and skin structure infection (SSSI), also referred to as skin and soft tissue infection (SSTI) or acute bacterial skin and skin structure infection (ABSSSI), is an infection of skin and associated soft tissues (such as loose connective tissue and mucous membranes). The pathogen involved is usually a bacterial species.TeicoplaninCreamed honey: Creamed honey is honey that has been processed to control crystallization. Creamed honey contains a large number of small crystals, which prevent the formation of larger crystals that can occur in unprocessed honey.CeftriaxoneBenzylpenicillinThioridazineAssay sensitivity: Assay sensitivity is a property of a clinical trial defined as the ability of a trial to distinguish an effective treatment from a less effective or ineffective intervention. Without assay sensitivity, a trial is not internally valid and is not capable of comparing the efficacy of two interventions.Thermal cyclerInfection Control and Hospital Epidemiology: Infection Control and Hospital Epidemiology is a peer-reviewed medical journal published by the University of Chicago Press. It publishes research on control and evaluation of the transmission of pathogens in healthcare institutions and on the use of epidemiological principles and methods to evaluate and improve the delivery of care, including infection control practices, surveillance, cost-benefit analyses, resource use, occupational health, and regulatory issues.Cell envelope: The cell envelope comprises the inner cell membrane and the cell wall of a bacterium, if present, plus a bacterial outer membrane, if one is present (i.e.Bacteremia: (NOS) |DimethylacetamideLinezolidStreptococcus dysgalactiae: Streptococcus dysgalactiae is a species of Streptococcus.Replica plating: 350px|right|thumb|[[Negative selection (artificial selection)|Negative selection through replica plating to screen for ampicillin sensitive colonies]]CefazolinHalotolerance: Halotolerance is the adaptation of living organisms to conditions of high salinity.Walter Larcher, 2001 Halotolerant species tend to live in areas such as hypersaline lakes, coastal dunes, saline deserts, salt marshes, and inland salt seas and springs.Enterococcus avium: Enterococcus avium, a species of Enterococcus, is most commonly found in birds. Rarely, it is also a cause of infection in humans, and in such cases, may be vancomycin-reistant, and is referred to as VREA.Pulsenet: PulseNet is a network run by the Centers for Disease Control and Prevention (CDC) which brings together public health and food regulatory agency laboratories around the United States.http://www.Multidrug-resistant gram-negative bacteria: MDRGN bacteria is an abbreviation for multidrug resistant gram-negative bacteria. For hospitalized patients, and especially patients in intensive care units, these bacterial infections pose a serious and (as of 2010) rapidly emerging threat.Phenotype microarray: The phenotype microarray approach is a technology for high-throughput phenotyping of cells.ATC code S01: ==S01A Anti-infectives==AmikacinOxacephem: An oxacephem is a molecule similar to a cephem, but with oxygen substituted for the sulfur. They are synthetic compounds not seen in nature.BiofilmBioline Reagents: Bioline Reagents is a primary manufacturer and developerBioline: The PCR Company | Company Profile of a wide range of specialised molecular biology products for the life science industry and research markets. It manufactures reagents including ultra-pure nucleotides, DNA polymerases and mixes, DNA markers, competent cells, products for RNA analysis and other general reagents for molecular biology.ClindamycinQuellung reaction: The Quellung reaction is a biochemical reaction in which antibodies bind to the bacterial capsule of Streptococcus pneumoniae, Klebsiella pneumoniae, Neisseria meningitidis, Haemophilus influenzae, Page 340 Escherichia coli, and Salmonella. The antibody reaction allows these species to be visualized under a microscope.Erythromycin 3''-O-methyltransferase: Erythromycin 3-O-methyltransferase (, EryG) is an enzyme with system name S-adenosyl-L-methionine:erythromycin C 3-O-methyltransferase. This enzyme catalyses the following chemical reactionPeptidoglycan binding domainNovobiocinCombination therapy: Combination therapy or polytherapy is therapy that uses more than one medication or modality (versus monotherapy, which is any therapy taken alone). Typically, these terms refer to using multiple therapies to treat a single disease, and often all the therapies are pharmaceutical (although it can also involve non-medical therapy, such as the combination of medications and talk therapy to treat depression).
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