It is a 94 kDa outer membrane protein encoded by eaeA gene in the locus of enterocyte effacement (LEE), a 35-Kb pathogenicity ... Intimin is expressed on the bacterial cell surface where it can bind to its receptor Tir (Translocated intimin receptor). Tir, ... Mutations in the eaeA gene result in loss of ability to cause A/E lesions, and is required for full virulence in infected ... Once within the cytoplasm of the host cell, Tir is inserted into the plasma membrane, allowing surface exposure and intimin ...
MicF in E. coli was found to regulate the expression of a key structural gene that makes up the outer membrane of the E. coli ... trans-encoded sRNAs interact with genes on separate loci. Amongst the targets of sRNAs are a number of house-keeping genes. The ... The outer membrane protein OmpA anchors the outer membrane to the murein layer of the periplasmic space. Its expression is ... The outer membrane of gram negative bacteria acts as a barrier to prevent the entry of toxins into the bacterial cell, and ...
The pel and psl loci are two recently discovered gene clusters that also encode exopolysaccharides found to be important for ... as it plays a key structural role in outer membrane integrity, as well as being an important mediator of host-pathogen ... Cell-surface polysaccharides play diverse roles in bacterial ecology and physiology. They serve as a barrier between the cell ... This "capsule" cloaks antigenic proteins on the bacterial surface that would otherwise provoke an immune response and thereby ...
Included are those involved in chemotaxis, outer membrane channel function, degradation of aromatic ring compounds, and the ... Generally, the bacterial species that divides fastest will be most effective at exploiting resources and effectively occupying ... The Caulobacter CB15 genome has 4,016,942 base pairs in a single circular chromosome encoding 3,767 genes. The genome contains ... and insertion/deletion polymorphisms at five chromosomal loci. C. crescentus is synonymous with Caulobacter vibrioides. ...
"A novel mechanism for the regulation of photosynthesis gene expression by the TspO outer membrane protein of Rhodobacter ... A homologue of the TspO protein in Sinorhizobium meliloti is involved in regulating expression of the ndi locus in response to ... Yeliseev AA, Krueger KE, Kaplan S (May 1997). "A mammalian mitochondrial drug receptor functions as a bacterial "oxygen" sensor ... In either prokaryotes or mitochondria they are localized to the outer membrane, and have been shown to bind and transport ...
... a sort of subclass-specific IgG antibody response to certain outer membrane proteins may also exist. Therefore, the outer ... The M. catarrhalis TAT translocase protein encoding genes tatA, tatB and tatC are located in a single tatABC locus in the ... Additionally, it causes bacterial pneumonia, especially in adults with a compromised immune system. It has also been known to ... The outer membrane protein (OMP) profiles of different strains of M. catarrhalis are extremely similar to each other. Analyses ...
Kuehn MJ, Kesty NC (November 2005). "Bacterial outer membrane vesicles and the host-pathogen interaction". Genes & Development ... "A virulence locus of Pseudomonas aeruginosa encodes a protein secretion apparatus". Science. 312 (5779): 1526-30. Bibcode: ... Bacterial effector protein Bacterial outer membrane vesicles Host-pathogen interface Membrane vesicle trafficking Secretomics ... the formation of bacterial outer membrane vesicles. Portions of the outer membrane pinch off, forming nano-scale spherical ...
The cagA gene codes for one of the major H. pylori virulence proteins. Bacterial strains with the cagA gene are associated with ... The outer membrane also contains cholesterol glucosides, which are present in few other bacteria. Helicobacter pylori consists ... About 29% of the loci have a colonization defect when mutated. Two of sequenced strains have an around 40 kb-long Cag ... H. pylori possesses five major outer membrane protein families. The largest family includes known and putative adhesins. The ...
The OspA and OspB genes encode the major outer membrane proteins of B. burgdorferi. The two Osp proteins show a high degree of ... Each locus consists of one or two Erp genes. When two genes are present, they are transcribed as one operon, although in some ... While each individual bacterial cell contains just one copy of the ospC gene, the gene sequence of ospC among different strains ... The outer membrane of B. burgdorferi is composed of various unique outer surface proteins (Osp) named OspA through OspF. Osp ...
These vesicles are produced from the outer membrane of myxobacterial cells and are found in large quantities within bacterial ... various genes including those encoding tRNAAsp and tRNAVal located at the attB locus (a phage attachment site), and so forth. ... These genes play a variety of roles in the developmental cycle. For example, in experiments where the fbFA gene was deactivated ... Another means for intercellular signaling could be via the exchange of outer membrane vesicles (OMVs). ...
... has been found to have six distinct secretion systems that mediate the export of protein through the inner and outer membranes ... Although dependent, the H. defensa genome preserves more genes and pathways for cell structures and processes, than that of ... Degnan PH, Yu Y, Sisneros N, Wing RA, Moran NA (June 2009). "Hamiltonella defensa, genome evolution of protective bacterial ... It also has several abundances: toxin homologs, encoding type-3 secretion systems, and putative pathogenicity loci. ...
... transports mercury through the outer membrane into the inner membrane where it holds the mercury for another protein to bind to ... MerR binds to an operator in the structural mer gene promoter called MerO. This binding causes the DNA of the mer loci to bend ... Thus, excess of the enzyme can result in bacterial death. Bacteria developed two regulatory proteins, MerR and MerD, for ... Mercury(II) reductase, commonly known as MerA, is encoded in a structural gene found on the mer loci or as transposon 501 ( ...
... osmoregulation of outer membrane proteins and virulence determinants in Vibrio cholerae requires toxR". Journal of Bacteriology ... Taylor, R. K.; Miller, V. L.; Furlong, D. B.; Mekalanos, J. J. (1987-05-01). "Use of phoA gene fusions to identify a pilus ... Miller, V L; Farmer, J J; Hill, W E; Falkow, S (1989). "The ail locus is found uniquely in Yersinia enterocolitica serotypes ... Miller is known for her research into bacterial pathogenesis, the factors leading to the onset of disease from specific species ...
osmB encodes an outer membrane lipoprotein that may play a role in cell aggregation (Jung et al., 1990) , whereas osmY encodes ... "The entericidin locus of Escherichia coli and its implications for programmed bacterial cell death". Journal of Molecular ... RpoS-dependent genes involved in changes in cell membrane permeability and general cell morphology mostly belong to the osm ... The gene rpoS (RNA polymerase, sigma S, also called katF) encodes the sigma factor sigma-38 (σ38, or RpoS), a 37.8 kD protein ...
The ACSF3 gene is located on chromosome 16 locus q24.3 and consists of 11 exons and encodes a 576-amino-acid protein. CMAMMA ... In the cytoplasm, malonyl-CoA acts as an inhibitor of the mitochondrial outer membrane enzyme carnitine palmitoyltransferase I ... Bacterial fermentation in the gut is a quantitatively significant source of propionate, which is a precursor for methylmalonic ... The MLYCD gene is located on chromosome 16 locus q23.3. ACSF3 encodes an acyl-CoA synthetase, which is localized in the ...
She mapped the loci of these mutations to a six-gene locus that she called Ids for identification of self. She later found that ... Gibbs explored the movement of surface proteins within bacterial membranes and on bacterial surface walls. During her PhD, ... Her thesis work utilized this tool to explore the dynamic distribution of LamB, an integral outer membrane protein in E. coli, ... Gibbs' research merges the fields of sociomicrobiology and bacterial cell biology to explore how the bacterial pathogen Proteus ...
The outcome is the regulation of transcription resulting in switches in gene expression. An outer membrane protein Antigen 43 ( ... Many bacterial species can utilize inversion to change the expression of certain genes for the benefit of the bacterium during ... P. atlantica contains an eps locus that encodes extracellular polysaccharide and the ON or OFF expression of this locus is ... There are several copies of the gene coding for these pili (the Pil gene) but only one is expressed at any given time. This is ...
... a hairpin orientation in the intestinal cell membrane to enable tight binding to intimin on the bacterial cell outer membrane. ... Tir is a receptor protein encoded by the espE gene which is located on the locus of enterocyte effacement (LEE) pathogenicity ... It is secreted into the host cell membranes and acts as a receptor for intimin which is found on the bacterial surface. Once ... Upon phosphorylation, Tir activates condensation and polymerization of actin filaments under the bacterial cell to form a ...
... s are necessary in Mycobacterium because of their impermeable membrane. The RD1 locus or Gene for Type ... This secretion system is composed of the following components: inner EccB5, outer EccB5, EccC5, inner EccD5, outer EccD5, EccE5 ... The bacterial genus Mycobacterium uses type VII secretion systems (T7SS) to secrete proteins across their cell envelope. The ... Disruption in the genes that encode T7SS called the RD1 locus results in the loss of function of secretion apparatus. The genes ...
While the outer membrane of E. coli contains porins that are permeable to phosphorylated compounds, the inner membrane does not ... which are determined by a minimum of three gene loci. Each one of these three loci controls a different kind of alkaline ... Some complexities of bacterial regulation and metabolism suggest that other, more subtle, purposes for the enzyme may also play ... The gene for tissue-nonspecific alkaline phosphatase is located on chromosome 1, and the genes for the other three isoforms are ...
Hinnebusch BJ, Perry RD, Schwan TG (July 1996). "Role of the Yersinia pestis hemin storage (hms) locus in the transmission of ... Mittal R, Peak-Chew SY, Sade RS, Vallis Y, McMahon HT (June 2010). "The acetyltransferase activity of the bacterial toxin YopJ ... These T3SS-injected proteins, called Yersinia outer proteins (Yops), include Yop B/D, which form pores in the host cell ... Some can regulate the virulence genes. Some 63 novel putative sRNAs were identified through deep sequencing of the Y. pestis ...
Humans possess two genes encoding pyrophosphatase, PPA1 and PPA2. PPA1 has been assigned to a gene locus on human chromosome 10 ... and occurs on the outer mitochondrial membrane. This activation is accomplished in two reactive steps: (1) the fatty acid ... "Functional complementation of yeast cytosolic pyrophosphatase by bacterial and plant H+-translocating pyrophosphatases". Proc. ... McAlpine PJ, Mohandas T, Ray M, Wang H, Hamerton JL (1976). "Assignment of the inorganic pyrophosphatase gene locus (PP) to ...
B. burgdorferi resembles other spirochetes in that it has an outer membrane and inner membrane with a thin layer of ... Bacterial transformation has been utilized by researchers in order to isolate specific pathogenic genes among the Borrelia ... Varying number of OspC loci are indications and determinants for the variations of B. burgdorferi. The surface protein is also ... However, the outer membrane lacks lipopolysaccharide. Its shape is a flat wave. It is about 0.3 μm wide and 5 to 20 μm in ...
The localization of some of the Pvd proteins in the periplasm and the outer membrane (such as PvdN, PvdO, PvdP, and PvdQ) have ... Several of the genes responsible for pyoverdine biosynthesis (e.g., pvdH, pvdA, and pvdF) are involved in the generation of ... Their contributions to bacterial pathogenesis include providing a crucial nutrient (i.e., iron), regulation of other virulence ... and claims that loss of activity in the locus has no effect on pyoverdine production. In addition, some fluorescent ...
... the bacterial cell and released only after destruction of the bacterial outer membrane. Subsequent work showed that release of ... Patil PB, Sonti RV (2004). "Variation suggestive of horizontal gene transfer at a lipopolysaccharide (lps) biosynthetic locus ... Kulp A, Kuehn MJ (2010). "Biological functions and biogenesis of secreted bacterial outer membrane vesicles". Annu. Rev. ... secreted as part of the normal physiological activity of membrane vesicle trafficking in the form of bacterial outer membrane ...
Chandran V, Fronzes R, Duquerroy S, Cronin N, Navaza J, Waksman G (December 2009). "Structure of the outer membrane complex of ... These genes are expressed from 4 different promoters located upstream of repA. repE encodes for a small antisense RNA and is ... Subsequently, oncogenic bacterial strains were found to be able to convert non-pathogenic bacteria into pathogens via the ... May 1989). "Nucleotide sequence and analysis of the plant-inducible locus pinF from Agrobacterium tumefaciens". Journal of ...
Leduc, I.; White, C. D.; Nepluev, I.; Throm, R. E.; Spinola, S. M.; Elkins, C. (2008). "Outer Membrane Protein DsrA Is the ... Cayrol B, Nogues C, Dawid A, Sagi I, Silberzan P, Isambert H (2009). "A Nanostructure Made of a Bacterial Noncoding RNA". J Am ... Sledjeski, D; Gottesman S (1995). "A small RNA acts as an antisilencer of the H-NS-silenced rcsA gene of Escherichia coli". ... RNA interactions at multiple loci". Proc Natl Acad Sci U S A. 95 (21): 12456-12461. Bibcode:1998PNAS...9512456L. doi:10.1073/ ...
Mutations in the FLS2 gene can cause bacterial infection by lack of response to flg22. Therefore,FLS2's primary focus is ... RLKs are transmembrane proteins that consists of inner, outer, and central membrane regions. Being proteins, they also have an ... Gómez-Gómez, Lourdes; Felix, Georg; Boller, Thomas (1999-05-01). "A single locus determines sensitivity to bacterial flagellin ... FLS genes have been discovered to be involved in flagellin reception of bacteria. FLS1 was the original gene discovered shown ...
Each Buchnera cell has an inner and outer gram-negative cell membrane and is individually enclosed in an aphid-derived ... of the genome and gene duplication present in more than 2000 gene families. These orphan genes and gene duplications are likely ... Studies on pea aphids have identified candidate loci, molecular and physiological mechanisms that are involved in host ... 2000). "Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS". Nature. 407 (6800): 81-86. Bibcode: ...
... vitelline membrane outer layer protein I (VMO-I) - WAC protein domain - Western blot - WHEP-TRS protein domain - WIF domain - ... gene - gene amplification - gene conversion - gene expression - gene mapping - gene pool - gene therapy - gene transfer - ... YecM bacterial protein domain - YjeF N terminal protein domain - YopH, N-terminal - YopR bacterial protein domain - Y Y Y - ... locus - LOD score - lymphocyte - lysine-tRNA(Pyl) ligase - M13 phage - m7G(5')pppN diphosphatase - malformation - maltose- ...