HHV capsid portal protein: HHV Capsid Portal Protein, or HSV-1 UL-6 protein, is the protein which forms a cylindrical portal in the capsid of Herpes simplex virus (HSV-1). The protein is commonly referred to as the HSV-1 UL-6 protein because it is the transcription product of Herpes gene UL-6.Andes virusSARS coronavirus: The SARS coronavirus, sometimes shortened to SARS-CoV, is the virus that causes severe acute respiratory syndrome (SARS). On April 16, 2003, following the outbreak of SARS in Asia and secondary cases elsewhere in the world, the World Health Organization (WHO) issued a press release stating that the coronavirus identified by a number of laboratories was the official cause of SARS.Coles PhillipsZinc fingerHexon protein: In molecular biology, the hexon protein is a major coat protein found in Adenoviruses. Hexon coat proteins are synthesised during late infection and form homo-trimers.Bunyamwera virus: The Bunyamwera virus is a negative-sense single stranded enveloped RNA virus. It is the type species of the Orthobunyavirus genus, in the Bunyaviridae family.Protein primary structure: The primary structure of a peptide or protein is the linear sequence of its amino acid structural units, and partly comprises its overall biomolecular structure. By convention, the primary structure of a protein is reported starting from the amino-terminal (N) end to the carboxyl-terminal (C) end.Nephropathia epidemicaCD46: CD46 complement regulatory protein also known as CD46 (cluster of differentiation 46) and Membrane Cofactor Protein is a protein which in humans is encoded by the CD46 gene. CD46 is an inhibitory complement receptor.Symmetry element: A symmetry element is a point of reference about which symmetry operations can take place. In particular, symmetry elements can be centers of inversion, axes of rotation and mirror planes.Vpx: Vpx is a virion-associated protein encoded by human immunodeficiency virus type 2 HIV-2 and most simian immunodeficiency virus (SIV) strains, but that is absent from HIV-1. It is similar in structure to the protein Vpr that is carried by SIV and HIV-2 as well as HIV-1.Timeline of the SARS outbreak: The following is a timeline of the 2002–04 outbreak of severe acute respiratory syndrome (SARS).Avian infectious bronchitis virus: Avian infectious bronchitis virus (IBV) is a coronavirus which infects chickens, causing the associated disease, infectious bronchitis (IB). It is a highly infectious avian pathogen which affects the respiratory tract, gut, kidney and reproductive systems of chickens.Arterivirus: Arterivirus is the only genus of viruses in the family Arteriviridae, which is within the order Nidovirales. Vertebrates serve as natural hosts.Belmont Park, Exeter: Belmont Park (also called Belmont Pleasure Grounds) is a public park in Exeter, England provided by Exeter City Council.Vesicular stomatitis virus: Vesicular stomatitis Indiana virus (VSIV) (often still referred to as VSV) is a virus in the family Rhabdoviridae; the well-known rabies virus belongs to the same family. VSIV can infect insects, cattle, horses and pigs.Puumala virus: Puumala virus (PUUV) is a species of hantavirus. Humans infected with the virus may develop a haemorrhagic fever with renal syndrome (HFRS) known as nephropathia epidemica.Influenza virus nucleoprotein: Influenza virus nucleoprotein (NP) is a structural protein which encapsidates the negative strand viral RNA. NP is one of the main determinants of species specificity.Viral structural protein: A viral structural protein is a viral protein that is a structural component of the mature virus.Nucleic acid structure: Nucleic acid structure refers to the structure of nucleic acids such as DNA and RNA. Chemically speaking, DNA and RNA are very similar.Schmallenberg virus: Schmallenberg virus is the informal name given to a recently isolated orthobunyavirus, which has not been given a formal name , initially reported in November 2011 to cause congenital malformations and stillbirths in cattle, sheep, goats, and possibly alpaca. It appears to be transmitted by midges (Culicoides spp.SFTS virus: The SFTS virus is a phlebovirus in the family Bunyaviridae.Fever with thrombocytopenia asshociated with a novel Bunyavirus in China.Sigma viruses: Sigma viruses are a clade of viruses in the family Rhabdoviridae that naturally infect dipterans, and have recently been proposed to represent a new genus of rhabdoviruses.Longdon B and Walker PJ (2011) Sigma virus genus proposal for the International Committee on Taxonomy of Viruses.Marburg marburgvirus: The species Marburg marburgvirus is the taxonomic home of two related viruses that form filamentous virions, Marburg virus (MARV) and Ravn virus (RAVV). Both viruses cause Marburg virus disease in humans and nonhuman primates, a form of viral hemorrhagic fever, and both are Select Agents, World Health Organization Risk Group 4 Pathogens (requiring Biosafety Level 4-equivalent containment), National Institutes of Health/National Institute of Allergy and Infectious Diseases Category A Priority Pathogens, Centers for Disease Control and Prevention Category A Bioterrorism Agents, and are listed as a Biological Agents for Export Control by the Australia Group.Peplomer: A peplomer is a glycoprotein spike on a viral capsid or viral envelope. as cited in These protrusions will only bind to certain receptors on the host cell: they are essential for both host specificity and viral infectivity.Bovine coronavirus: Bovine coronavirus (BCV) is as a member of the Coronaviridae family which are enveloped, single-stranded, positive-sense RNA viruses with a club-shaped surface. Infection causes 'Calf Enteritis' and contributes to the 'Enzootic Pneumonia complex' in calves.Sindbis virusDistributed cache: In computing, a distributed cache is an extension of the traditional concept of cache used in a single locale. A distributed cache may span multiple servers so that it can grow in size and in transactional capacity.Pseudotyping: Pseudotyping is the process of producing viruses or viral vectors in combination with foreign viral envelope proteins. The result is a pseudotyped virus particle.Proximity ligation assay: Proximity ligation assay (in situ PLA) is a technology that extends the capabilities of traditional immunoassays to include direct detection of proteins, protein interactions and modifications with high specificity and sensitivity. Protein targets can be readily detected and localized with single molecule resolution and objectively quantified in unmodified cells and tissues.Influenza virus matrix protein 2: Matrix protein 2 of Influenza virus is a single-spanning transmembrane protein. It is expressed on the infected cell surface and incorporated into virions where it is a minor component.Eva Engvall: Eva Engvall, born 1940, is one of the scientists who invented ELISA in 1971.Eva Engvall, The Scientist 1995, 9(18):8Coronavirus 3' stem-loop II-like motif (s2m)Rinderpest: Rinderpest (also cattle plague or steppe murrain) was an infectious viral disease of cattle, domestic buffalo, and some other species of even-toed ungulates, including buffaloes, large antelope and deer, giraffes, wildebeests, and warthogs. The disease was characterized by fever, oral erosions, diarrhea, tenesmus, lymphoid necrosis, and high mortality.Epitope mapping: Epitope mapping is the process of experimentally identifying the binding sites, or ‘epitopes’, of antibodies on their target antigens. Identification and characterization of the binding sites of antibodies can aid in the discovery and development of new therapeutics, vaccines, and diagnostics.Arroyo (creek): An arroyo (; , "brook"), also called a wash, is a dry creek, stream bed or gulch that temporarily or seasonally fills and flows after sufficient rain. Flash floods are common in arroyos following thunderstorms.Toroidal polyhedron: In geometry, a toroidal polyhedron is a polyhedron which is also a toroid (a g-holed torus), having a topological genus, g, of 1 or greater.DNA binding site: DNA binding sites are a type of binding site found in DNA where other molecules may bind. DNA binding sites are distinct from other binding sites in that (1) they are part of a DNA sequence (e.Progressive rubella panencephalitis: Progressive rubella panencephalitis (PRP) is a neurological disorder which may occur in a child with congenital rubella. It is a slow viral infection of the brain characterized by chronic encephalitis, usually manifesting between 8–19 years of age.Vesiculovirus matrix proteins: The family of vesiculovirus matrix proteins consists of several matrix proteins of the vesicular stomatitis virus, also known as VSIV or VSV. The matrix (M) protein of the virus causes many of the cytopathic effects of VSV, including an inhibition of host gene expression and the induction of cell rounding.California encephalitis virusNucleic acid secondary structure: The secondary structure of a nucleic acid molecule refers to the basepairing interactions within a single molecule or set of interacting molecules, and can be represented as a list of bases which are paired in a nucleic acid molecule.C. J. Peters: Clarence James Peters, Jr, M.D.Eukaryotic transcription: Eukaryotic transcription is the elaborate process that eukaryotic cells use to copy genetic information stored in DNA into units of RNA replica. Gene transcription occurs in both eukaryotic and prokaryotic cells.Transmissible gastroenteritis coronavirus: Transmissible Gastroenteritis Coronavirus (TGEV) is a virus belonging to the family Coronaviridae, genus Alphacoronavirus, species Alphacoronavirus 1. TGEV are enveloped viruses with a positive-sense single-stranded RNA genome and a helical symmetry.La Crosse (grape): La Crosse is a modern hybrid cultivar of wine grape, mostly grown in North America. It produces grapes suitable for making fruity white wines similar to Riesling or as a base for blended wines.Simian retrovirus: Simian retrovirus (SRV) is a species of retroviruses that usually infect and cause a fatal immune deficiency in Asian macaques. This virus appears sporadically in captive macaques at breeding facilities which expected as the natural host, but prevalence of this virus in feral macaques remain unknown.Chemically induced dimerization: Chemically Induced Dimerization (CID) is a biological mechanism in which two proteins bind only in the presence of a certain small molecule, enzyme or other dimerizing agent. Genetically engineered CID systems are used in biological research to control protein localization, to manipulate signalling pathways and to induce protein activation.Argentine hemorrhagic feverSilent mutation: Silent mutations are mutations in DNA that do not significantly alter the phenotype of the organism in which they occur. Silent mutations can occur in non-coding regions (outside of genes or within introns), or they may occur within exons.Ligation-independent cloning: Ligation-independent cloning (LIC) is a form of molecular cloning that is able to be performed without the use of restriction endonucleases or DNA ligase. This allows genes that have restriction sites to be cloned without worry of chopping up the insert.Gammaretrovirus core encapsidation signalBaby hamster kidney cell: Baby Hamster Kidney fibroblasts (aka BHK cells) are an adherent cell line used in molecular biology.Low-voltage electron microscope: Low-voltage electron microscope (LVEM) is an electron microscope which operates at accelerating voltages of a few kiloelectronvolts or less. While the low voltage electron microscopy technique will never replace conventional high voltage electron microscopes, it is quickly becoming appreciated for many different disciplines.Cryptic self epitopes: In immunology, cryptic self epitopes are a source of autoimmunity.Arenavirus: An arenavirus is a virus which is a member of the family Arenaviridae. These viruses infect rodents and occasionally humans; arenaviruses have also been discovered which infect snakes.
Download our free solidary book to support research on VHL disease