Neutrophil granulocyteMyeloperoxidase deficiency: Myeloperoxidase deficiency is an autosomal recessive genetic disorder featuring deficiency, either in quantity or of function, of myeloperoxidase, an enzyme found in certain phagocytic immune cells, especially polymorphonuclear leukocytes.Phagocytosis: In cell biology, phagocytosis ( (phagein) |to devour||, (kytos) |cell||-osis|process}}) is the process by which a cell—often a phagocyte or a protist—engulfs a solid particle to form an internal vesicle known as a phagosome. Phagocytosis was first noted by Canadian physician William Osler, and later studied by Élie Metchnikoff.Potassium superoxideLeukotriene B4Cell adhesionElastaseCathepsin G: Cathepsin G (, chymotrypsin-like proteinase, neutral proteinase) is an enzymatic protein belonging to the peptidase or protease families. In humans, it is coded by the CTSG gene.ZymosanInflammation: Inflammation (Latin, [is part of the complex biological response of body tissues to harmful stimuli, such as pathogen]s, damaged cells, or irritants.Tetratricopeptide: B:89-122 A:522-555 B:228-261ImmunodeficiencyFormyl peptide receptor: The formyl peptide receptors (FPR) belong to a class of G protein-coupled receptors involved in chemotaxis. These receptors were originally identified by their ability to bind N-formyl peptides such as N-formylmethionine produced by the degradation of either bacterial or host cells.Haptotaxis: Haptotaxis (from Greek ἅπτω (hapto, "touch, fasten") and τάξις (taxis, "arrangement, order")) is the directional motility or outgrowth of cells, e.g.Specific granule: Specific granules are secretory vesicles found exclusively in cells of the immune system called granulocytes.Lung receptor: Lung receptors sense irritation or inflammation in the bronchi and alveoli.Phorbol 12,13-dibutyrateCompound 48/80: Compound 48/80 is a polymer produced by the condensation of N-methyl-p-methoxyphenethylamine with formaldehyde.Compound48/80 at Sigma-Aldrich It promotes histamine release, and in biochemical research, compound 48/80 is used to promote mast cell degranulation.Dioxetane: A dioxetane or dioxacyclobutane is an organic compound with formula C2O2H4, whose backbone is a four-membered ring of two oxygen atoms and two carbon atoms. There are two isomers:PegfilgrastimG-CSF factor stem-loop destabilising elementCD32: ; ; rendered via PyMOL.Flow cytometry: In biotechnology, flow cytometry is a laser-based, biophysical technology employed in cell counting, cell sorting, biomarker detection and protein engineering, by suspending cells in a stream of fluid and passing them by an electronic detection apparatus. It allows simultaneous multiparametric analysis of the physical and chemical characteristics of up to thousands of particles per second.Chemokine: A:24-90 :24-90 A:24-90Lactoferrin: Lactoferrin (LF), also known as lactotransferrin (LTF), is a multifunctional protein of the transferrin family. Lactoferrin is a globular glycoprotein with a molecular mass of about 80 kDa that is widely represented in various secretory fluids, such as milk, saliva, tears, and nasal secretions.Siderocalin: Siderocalin (Scn), lipocalin-2, NGAL, 24p3 is a mammalian lipocalin-type protein that can prevent iron acquisition by pathogenic bacteria by binding siderophores, which are iron-binding chelators made by microorganisms.Granulocyte macrophage colony-stimulating factorCyclic neutropeniaAdecatumumabChemotaxis: Chemotaxis (from chemo- + taxis) is the movement of an organism in response to a chemical stimulus. Somatic cells, bacteria, and other single-cell or multicellular organisms direct their movements according to certain chemicals in their environment.Hypochlorous acidCXCL14: Chemokine (C-X-C motif) ligand 14 (CXCL14) is a small cytokine belonging to the CXC chemokine family that is also known as BRAK (for breast and kidney-expressed chemokine).Hromas, R.Proinflammatory cytokine: A proinflammatory cytokine is a cytokine which promotes systemic inflammation.P-selectin glycoprotein ligand-1: Selectin P ligand, also known as SELPLG or CD162 (cluster of differentiation 162), is a human gene.Eosinophil granulocyteTingible body macrophage: A tingible body macrophage is a type of macrophage predominantly found in germinal centers, containing many phagocytized, apoptotic cells in various states of degradation, referred to as tingible bodies (tingible meaning stainable).Horst Ibelgaufts' COPE: Cytokines & Cells Online Pathfinder Encyclopaedia > tingible body macrophages Retrieved on June 27, 2010 Tingible body macrophages contain condensed chromatin fragments.Granulocyte: framed|Eosinophilic granulocyteDown syndrome cell adhesion molecule like 1: Down syndrome cell adhesion molecule like 1 is a protein in humans that is encoded by the DSCAML1 gene.Amphibacillus xylanus: Amphibacillus xylanus or A. xylanus is a gram-positive-spore forming bacterium with cells 0.Mitochondrial ROS: Mitochondrial ROS (mtROS or mROS) are reactive oxygen species (ROS) that are produced by mitochondria. Generation of mitochondrial ROS mainly takes place at the electron transport chain located on the inner mitochondrial membrane during the process of oxidative phosphorylation (OXPHOS).CD36 antigen: CD36 antigen is a transmembrane, highly glycosylated, glycoprotein expressed by monocytes, macrophages, platelets, microvascular endothelial cells and adipose tissues. CD36 recognises oxidized low density lipoprotein, long chain fatty acids, anionic phospholipids, collagen types I, IV and V, thrombospondin and Plasmodium falciparum infected erythrocytes.Gross pathology: Gross pathology refers to macroscopic manifestations of disease in organs, tissues, and body cavities. The term is commonly used by anatomical pathologists to refer to diagnostically useful findings made during the gross examination portion of surgical specimen processing or an autopsy.Intercellular adhesion molecule: In molecular biology, intercellular adhesion molecules (ICAMs) and vascular cell adhesion molecule-1 (VCAM-1) are part of the immunoglobulin superfamily. They are important in inflammation, immune responses and in intracellular signalling events.Temporal analysis of products: Temporal Analysis of Products (TAP), (TAP-2), (TAP-3) is an experimental technique for studyingAcute-phase protein: Acute-phase proteins are a class of proteins whose plasma concentrations increase (positive acute-phase proteins) or decrease (negative acute-phase proteins) in response to inflammation. This response is called the acute-phase reaction (also called acute-phase response).Monoclonal antibody therapyPulmonary-renal syndrome: Pulmonary-renal syndrome is a rare medical syndrome involving bleeding in the lungs and kidney damage (glomerulonephritis).Theta defensin: Theta-defensins (θ-defensins. retrocyclins) are a family of mammalian antimicrobial peptides.Burst kinetics: Burst kinetics is a form of enzyme kinetics that refers to an initial high velocity of enzymatic turnover when adding enzyme to substrate. This initial period of high velocity product formation is referred to as the "Burst Phase".Cathepsin: Cathepsins (Ancient Greek kata- "down" and hepsein "boil"; abbreviated CTS) are proteases (enzymes that degrade proteins) found in all animals as well as other organisms. There are approximately a dozen members of this family, which are distinguished by their structure, catalytic mechanism, and which proteins they cleave.Spontaneous bacterial peritonitisCalcium signaling: Calcium ions are important for cellular signalling, as once they enter the cytosol of the cytoplasm they exert allosteric regulatory effects on many enzymes and proteins. Calcium can act in signal transduction resulting from activation of ion channels or as a second messenger caused by indirect signal transduction pathways such as G protein-coupled receptors.Vaporized hydrogen peroxide: Vaporized hydrogen peroxide — also known as hydrogen peroxide vapor, HPV, and by the trademarked name VHP — is a vapor form of hydrogen peroxide (H2O2) with applications as a low-temperature antimicrobial vapor used to decontaminate enclosed and sealed areas such as laboratory workstations, isolation and pass-through rooms, and even aircraft interiors.Concentration effect: In the study of inhaled anesthetics, the concentration effect is the increase in the rate that the Fa(alveolar concentration)/Fi(inspired concentration) ratio rises as the alveolar concentration of that gas is increased. In simple terms, the higher the concentration of gas administered, the faster the alveolar concentration of that gas approaches the inspired concentration.Endothelial activation: Endothelial activation is a proinflammatory and procoagulant state of the endothelial cells lining the lumen of blood vessels. It is most characterized by an increase in interactions with white blood cells (leukocytes), and it is associated with the early states of atherosclerosis and sepsis, among others.Cell membraneExtremophile: An extremophile (from Latin meaning "extreme" and Greek () meaning "love") is an organism that thrives in physically or geochemically extreme conditions that are detrimental to most life on Earth. In contrast, organisms that live in more moderate environments may be termed mesophiles or neutrophiles.
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