Myokine: A myokine is one of several hundred cytokines or other small proteins (~5–20 kDa) and proteoglycan peptides that are produced and released by muscle cells (myocytes) in response to muscular contractions.Bente Klarlund Pedersen , Thorbjörn C.Protein turnover: Protein turnover is the balance between protein synthesis and protein degradation. More synthesis than breakdown indicates an anabolic state that builds lean tissues, more breakdown than synthesis indicates a catabolic state that burns lean tissues.Myopathy: -, - |Acquired non-inflammatory myopathy: Acquired non-inflammatory myopathy (ANIM) is a neurological disorder primarily affecting skeletal muscle, most commonly in the limbs of humans, resulting in a weakness or dysfunction in the muscle. A myopathy refers to a problem or abnormality with the myofibrils, which compose muscle tissue.Muscle contraction: Muscle contraction is the activation of tension-generating sites within muscle fibers. In physiology, muscle contraction does not mean muscle shortening because muscle tension can be produced without changes in muscle length such as holding a heavy book or a dumbbell at the same position.Fields' disease: Fields' disease is considered to be one of the rarest known diseases in the world, with only two diagnosed cases in history. It is named after Welsh twins Catherine and Kirstie Fields.Vascular smooth muscleWeaknessPolymyositisExercise therapy for idiopathic inflammatory myopathies: Although they vary in particulars, polymyositis, dermatomyositis and inclusion body myositis are idiopathic inflammatory myopathies (IIM)primarily characterized by chronic inflammation] of human [[skeletal muscle tissueLundberg I. and Y-L Chung, 2000.Synaptogenesis: Synaptogenesis is the formation of synapses between neurons in the nervous system. Although it occurs throughout a healthy person's lifespan, an explosion of synapse formation occurs during early brain development, known as exuberant synaptogenesis.Diaphragmatic excursion: Diaphragmatic excursion is the movement of the thoracic diaphragm during breathing.Quadriceps tendon ruptureAging movement control: Normal aging movement control in humans is about the changes on the muscles, motor neurons, nerves, sensory functions, gait, fatigue, visual and manual responses, in men and women as they get older but who do not have neurological, muscular (atrophy, dystrophy...) or neuromuscular disorder.Dermatomyositis: - (ILDS M33.910)Thyrotoxic periodic paralysisCongenital myopathyHelp Cure Muscular Dystrophy: Help Cure Muscular Dystrophy is a distributed computing project that runs on the BOINC platform. It is a joint effort of the French muscular dystrophy charity, L'Association française contre les myopathies;French Muscular Dystrophy Association and L'Institut de biologie moléculaire et cellulaire (Molecular and Cellular Biology Institute).HypersensitivityLambert–Eaton myasthenic syndromeInclusion body myositisInferior rectus muscle: The inferior rectus muscle is a muscle in the orbit.Sternohyoid muscle: The sternohyoid muscle is a thin, narrow muscle attaching the hyoid bone to the sternum, one of the paired strap muscles of the infrahyoid muscles serving to depress the hyoid bone. It is innervated by the ansa cervicalis.Brian Steel: Brian Charles Steel is a photographer based in Atlanta, Georgia, known for his lyrical and sympathetic portrayals of individuals with disabilities. He was diagnosed as an infant with a rare muscle disorder that left him handicapped, inspiring him to create art that belies his condition.Exon skipping: In molecular biology, exon skipping is a form of RNA splicing used to cause cells to “skip” over faulty or misaligned sections of genetic code, leading to a truncated but still functional protein despite the genetic mutation.Dynamometer car: A dynamometer car is a railroad maintenance of way car used for measuring various aspects of a locomotive's performance. Measurements include tractive effort (pulling force), power, top speed, etc.Dysferlinopathy: Dysferlinopathy is an autosomal recessive neuromuscular disorder caused by a deficiency of functional dysferlin protein due to mutations in the dysferlin gene. Dysferlinopathy is characterized by progressive muscle wasting and is most often clinically diagnosed as Limb-girdle muscular dystrophy type 2B (LGMD2B) or Miyoshi muscular dystrophy 1 (MMD1; a type of distal muscular dystrophy), depending on the initial pattern of muscle involvement at diagnosis.Intrafusal muscle fiberEnd-plate potential: End plate potentials (EPPs) are the depolarizations of skeletal muscle fibers caused by neurotransmitters binding to the postsynaptic membrane in the neuromuscular junction. They are called "end plates" because the postsynaptic terminals of muscle fibers have a large, saucer-like appearance.RhabdomyolysisMYH7: MYH7 is a gene encoding a myosin heavy chain beta (MHC-β) isoform (slow twitch) expressed primarily in the heart, but also in skeletal muscles (type I fibers). This isoform is distinct from the fast isoform of cardiac myosin heavy chain, MYH6, referred to as MHC-α.OphthalmoparesisDavid Laing (antiquary)Muscular Dystrophy AssociationHypokalemiaMyotonic dystrophyMyofibrilPower tower (exercise): A power tower, also known as a knee raise station, and sometimes referred to as a captain's chair, is a piece of exercise equipment that allows one to build upper body and abdominal muscle strength. When only the forearm pads alone are used for performing abdominal exercises, usually referred to as simply 'the captain's chair.Facial muscles: The facial muscles are a group of striated skeletal muscles innervated by the facial nerve (cranial nerve VII) that, among other things, control facial expression. These muscles are also called mimetic muscles.Charcot–Marie–Tooth disease: Charcot disease}}Toxicity label: Toxicity labelsThe Tribune. 'Knowing labels can save lives' by Divender Gupta.William Canfield: William Canfield is a glycobiologist, chief scientific officer and founder of an Oklahoma City-based biotechnology company, Novazyme, which was acquired by Genzyme in August 2001 and developed, among other things, an enzyme that can stabilize (but not cure) Pompe disease, based on Canfield's ongoing research since 1998.http://staging.Creatine kinaseMasticatory force: Masticatory force or force of mastication is defined as a force, which is created by the dynamic action of the masticatory muscles during the physiological act of chewing.Potassium-aggravated myotonia: Potassium-aggravated myotonia is a rare genetic disorder that affects skeletal muscle. Beginning in childhood or adolescence, people with this condition experience bouts of sustained muscle tensing (myotonia) that prevent muscles from relaxing normally.Muscles of respiration: In human physiology, the muscles of respiration are those muscles that contribute to inhalation and exhalation, by aiding in the expansion and contraction of the thoracic cavity. The diaphragm and, to a lesser extent, the intercostal muscles drive respiration during quiet breathing.Mechanochemistry: Mechanochemistry or mechanical chemistry is the coupling of mechanical and chemical phenomena on a molecular scale and includes mechanical breakage, chemical behaviour of mechanically stressed solids (e.g.Susan Perlman: Susan Perlman (born c. 1949) is a Professor in the Department of Neurology at the David Geffen School of Medicine at UCLA.Temporal analysis of products: Temporal Analysis of Products (TAP), (TAP-2), (TAP-3) is an experimental technique for studyingDystrophin: Dystrophin is a rod-shaped cytoplasmic protein, and a vital part of a protein complex that connects the cytoskeleton of a muscle fiber to the surrounding extracellular matrix through the cell membrane. This complex is variously known as the costamere or the dystrophin-associated protein complex.Renshaw cell: Renshaw cells are inhibitory interneurons found in the gray matter of the spinal cord, and are associated in two ways with an alpha motor neuron.Congenital distal spinal muscular atrophy: Congenital distal spinal muscular atrophy (congenital dSMA) is a hereditary genetic condition characterized by muscle wasting (atrophy), particularly of distal muscles in legs and hands, and by early-onset contractures (permanent shortening of a muscle or joint) of the hip, knee, and ankle. Affected individuals often have shorter lower limbs relative to the trunk and upper limbs.Juvenile primary lateral sclerosis: Juvenile primary lateral sclerosis (JPLS) , also known as primary lateral sclerois (PLSJ), is a rare genetic disorder, with a small number of reported cases, characterized by progressive weakness and stiffness of muscles in the arms, legs, and face. The disorder damages motor neurons, which are specialized nerve cells in the brain and spinal cord that control muscle movement.Pedigree chart: A pedigree chart is a diagram that shows the occurrence and appearance or phenotypes of a particular gene or organism and its ancestors from one generation to the next,pedigree chart Genealogy Glossary -, a part of The New York Times Company.MyocytePhenotype microarray: The phenotype microarray approach is a technology for high-throughput phenotyping of cells.Calcium signaling: Calcium ions are important for cellular signalling, as once they enter the cytosol of the cytoplasm they exert allosteric regulatory effects on many enzymes and proteins. Calcium can act in signal transduction resulting from activation of ion channels or as a second messenger caused by indirect signal transduction pathways such as G protein-coupled receptors.Flaccid paralysisCortical stimulation mapping: Cortical stimulation mapping (often shortened to CSM) is a type of electrocorticography that involves a physically invasive procedure and aims to localize the function of specific brain regions through direct electrical stimulation of the cerebral cortex. It remains one of the earliest methods of analyzing the brain and has allowed researchers to study the relationship between cortical structure and systemic function.Electric torque wrenchGross pathology: Gross pathology refers to macroscopic manifestations of disease in organs, tissues, and body cavities. The term is commonly used by anatomical pathologists to refer to diagnostically useful findings made during the gross examination portion of surgical specimen processing or an autopsy.Silent mutation: Silent mutations are mutations in DNA that do not significantly alter the phenotype of the organism in which they occur. Silent mutations can occur in non-coding regions (outside of genes or within introns), or they may occur within exons.Compound muscle action potential: The compound muscle action potential (CMAP) or compound motor action potential is an electromyography investigation (electrical study of muscle function).Pursed lip breathing: Pursed lip breathing (PLB) is the breathing technique that consists of exhaling through tightly pressed (pursed lips) and inhaling through nose with mouth closed. Physicians, physical therapists, occupational therapists, and respiratory therapists teach this technique to their patients to ease shortness of breath and to promote deep breathing, also referred to as abdominal or diaphragmatic breathing.Rectus capitis posterior major muscle: The Rectus capitis posterior major (or Rectus capitis posticus major, both being Latin for larger posterior straight muscle of the head) arises by a pointed tendon from the spinous process of the axis, and, becoming broader as it ascends, is inserted into the lateral part of the inferior nuchal line of the occipital bone and the surface of the bone immediately below the line.Bulbar palsyOculopharyngeal muscular dystrophyMalformative syndrome: A malformative syndrome (or malformation syndrome) is a recognizable pattern of congenital anomalies that are known or thought to be causally related (VIIth International Congress on Human Genetics).Brain biopsyMonomelic amyotrophy: Monomelic amyotrophy (MMA), also known as Hirayama disease, Sobue disease, juvenile non-progressive amyotrophy and juvenile asymmetric segmental spinal muscular atrophy (JASSMA) — is an untreatable, focal motor neuron disease that primarily affects young (15- to 25-year-old) males in India and Japan. MMA is marked by insidious onset of muscular atrophy, which stabilizes at a plateau after two to five years from which it neither improves nor worsens.Facioscapulohumeral muscular dystrophy