DegranulationCompound 48/80: Compound 48/80 is a polymer produced by the condensation of N-methyl-p-methoxyphenethylamine with formaldehyde.Compound48/80 at Sigma-Aldrich It promotes histamine release, and in biochemical research, compound 48/80 is used to promote mast cell degranulation.Tryptase: Tryptase (, ) is the most abundant secretory granule-derived serine proteinase contained in mast cells and has been used as a marker for mast cell activation. The biological function of tryptase is unclear.GomiliximabXanthelasmoidal mastocytosis: Xanthelasmoidal mastocytosis is a cutaneous condition characterized by numerous, confluent, yellow–tan papules.Disodium guanylateMotesanibHistamine dihydrochloride: Histamine dihydrochloride (INN, trade name Ceplene) is a salt of histamine which is used as a drug for the prevention of relapse in patients diagnosed with acute myeloid leukemia (AML). It is an FDA approvedhttp://www.Anaphylaxis Campaign: The Anaphylaxis Campaign is the only UK charity to exclusively meet the needs of the growing numbers of people at risk from severe allergic reactions by providing information and support relating to foods and other triggers such as latex, drugs and insect stings.The Anaphylaxis CampaignProlyl endopeptidase: Prolyl endopeptidase (PE) also known as prolyl oligopeptidase or post-proline cleaving enzyme is an enzyme that in humans is encoded by the PREP gene.AncestimPeritoneal cavityMast cell leukemiaBasophil cellKetotifenSpecific granule: Specific granules are secretory vesicles found exclusively in cells of the immune system called granulocytes.Neuromorphology: Neuromorphology (from Greek νεῦρον, neuron, "nerve"; μορφή, morphé, “form”; -λογία, -logia, “study of”[is the study of nervous system] form, shape, and structure. The study involves looking at a particular part of the nervous system from a [[Molecular biology|molecular and cellular level and connecting it to a physiological and anatomical point of view.Dermal equivalent: The dermal equivalent is an in vitro model of the dermal layer of skin. It is constructed by seeding dermal fibroblasts into a collagen gel.Mast cell sarcomaToluidine blue stainUrticaria pigmentosaOxatomideWandering cell: In anatomy and histology, the term wandering cell (or ameboid cell)ameboid+cell at eMedicine Dictionary is used to describe cells that are found in connective tissue, but are not fixed in place. This term is used occasionally and usually refers to blood leukocytes (which are not fixed and organized in solid tissue) in particular mononuclear phagocytes.RBL cells: RBL (Rat Basophilic Leukemia cells) Bingham B.R.Leukotriene C4Proinflammatory cytokine: A proinflammatory cytokine is a cytokine which promotes systemic inflammation.International Conference on Trichinellosis: The International Commission on Trichinellosis (ICT) was created in 1958 in Budapest and is aiming to exchange information on the biology, the physiopathology, the epidemiology, the immunology, and the clinical aspects of trichinellosis in humans and animals. Prevention is a primary goal (see ICTweb pages).Nippostrongylus brasiliensis: Nippostrongylus brasiliensis is a gastrointestinal roundworm or nematode that infects rodents, primarily rats. This worm is a widely studied parasite due to its simple life-cycle and its ability to be used in animal models.Microphthalmia-associated transcription factor: Microphthalmia-associated transcription factor also known as class E basic helix-loop-helix protein 32 or bHLHe32 is a protein that in humans is encoded by the MITF gene.ExocytosisEosinophil granulocyteLung receptor: Lung receptors sense irritation or inflammation in the bronchi and alveoli.MeciadanolHistory and naming of human leukocyte antigens: Human leukocyte antigens (HLA) began as a list of antigens identified as a result of transplant rejection. The antigens were initially identified by categorizing and performing massive statistical analyses on interactions between blood types.Mature messenger RNA: Mature messenger RNA, often abbreviated as mature mRNA is a eukaryotic RNA transcript that has been spliced and processed and is ready for translation in the course of protein synthesis. Unlike the eukaryotic RNA immediately after transcription known as precursor messenger RNA, it consists exclusively of exons, with all introns removed.Calcium signaling: Calcium ions are important for cellular signalling, as once they enter the cytosol of the cytoplasm they exert allosteric regulatory effects on many enzymes and proteins. Calcium can act in signal transduction resulting from activation of ion channels or as a second messenger caused by indirect signal transduction pathways such as G protein-coupled receptors.Inflammation: Inflammation (Latin, [is part of the complex biological response of body tissues to harmful stimuli, such as pathogen]s, damaged cells, or irritants.Allergen immunotherapy: Allergen immunotherapy, also known as desensitization or hypo-sensitization, is a medical treatment for some types of allergies. It is useful for environmental allergies, allergies to insect bites, and asthma.
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