Age-Related Eye Disease Study: The Age-Related Eye Disease Study (AREDS) was a clinical trial sponsored by the National Eye Institute, one of the National Institutes of Health in the United States.A Randomized, Placebo-Controlled, Clinical Trial of High-Dose Supplementation With Vitamins C and E, Beta Carotene, and Zinc for Age-Related Macular Degeneration and Vision Loss.LogMAR chart: A LogMAR chart comprises rows of letters and is used by ophthalmologists and vision scientists to estimate visual acuity. This chart was developed at the National Vision Research Institute of Australia in 1976, and is designed to enable a more accurate estimate of acuity as compared to other charts (e.Factor H: Factor H is a member of the regulators of complement activation family and is a complement control protein. It is a large (155 kilodaltons), soluble glycoprotein that circulates in human plasma (at typical concentrations of 200–300 micrograms per milliliter).Carol S. Bruch: Carol Sophie Bruch (born June 11, 1941) is an American legal scholar and professor emerita of the law school at the University of California, Davis. A recognized authority on family marital property law, and private international law, she has influenced and worked on the drafting of family law statutes in California and other US states, and also international agreements.Ron Gallemore: Ron P. Gallemore is a registered ophthalmologist with the American Academy of OphthalmologyThe American Academy of Ophthalmology Dr Ron Gallemore certification involved in research and treatment of diseases of the macula and retina.Retinal regeneration: Retinal regeneration deals with restoring retinal function to vertebrates so impaired.LipofuscinOptic disc drusenWallerian degeneration: Wallerian degeneration is a process that results when a nerve fiber is cut or crushed, in which the part of the axon separated from the neuron's cell body degenerates distal to the injury.Trauma and Wallerian Degeneration, University of California, San Francisco This is also known as anterograde or orthograde degeneration.Coherence theory: In physics, coherence theory is the study of optical effects arising from partially coherent light and radio sources. Partially coherent sources are sources where the coherence time or coherence length are limited by bandwidth, by thermal noise, or by other effect.Serpiginous: Serpiginous, often referring to some chronic medical affliction, signifies it as slowly progressive or "creeping", such as ringworm. Regarding skin ailments in particular, this means that such a disease leaves scar tissue below while continuing to affect the skin above.Macula of retina: The macula or macula lutea (from Latin macula, "spot" + lutea, "yellow") is an oval-shaped pigmented area near the center of the retina of the human eye. It has a diameter of around .HU-336Transudate: Transudate is extravascular fluid with low protein content and a low specific gravity (< 1.012).Photoimmunotherapy: Photoimmunotherapy (PIT) is a new type of molecular targeted cancer therapy, which allows the selective destruction of cancer cells in mice without any damage to normal tissues. It is a light-based cancer therapy, which was developed by Professor Kobayashi and his colleagues at National Cancer Institute, Bethesda, Maryland.Degenerative disc diseaseScanning laser ophthalmoscopyXanthophyllOutline of photography: The following outline is provided as an overview of and topical guide to photography:ScotomaPurtscher's retinopathy: Purtscher's retinopathy is a disease where part of the eye (retina) is damaged. Usually associated with severe head injuries, it may also occur with other types of trauma, such as long bone fractures, or with several non-traumatic systemic diseases.BevacizumabNeuro-ophthalmology: Neuro-ophthalmology is an academically-oriented subspecialty that merges the fields of neurology and ophthalmology, often dealing with complex systemic diseases that have manifestations in the visual system. Neuro-ophthalmologists initially complete a residency in either neurology or ophthalmology, then do a fellowship in the complementary field.Optic disc pit: An optic disc pit is a congenital excavation (or regional depression) of the optic nerve head resulting from a malformation during development of the eye. Optic pits are important because they are associated with posterior vitreous detachments (PVD) and even serous retinal detachments.Retinal haemorrhageOperation Eyesight Universal: Operation Eyesight Universal is a Canada-based international development organisation, founded in 1963. It works to prevent avoidable blindness and to cure blindness that is treatable.Low vision assessment: Low vision is both a subspeciality and a condition. Optometrists and Ophthalmologists after their training may undergo further training in Low vision assessment and management.WGAViewer: WGAViewer is a bioinformatics software tool which is designed to visualize, annotate, and help interpret the results generated from a genome wide association study (GWAS). Alongside the P values of association, WGAViewer allows a researcher to visualize and consider other supporting evidence, such as the genomic context of the SNP, linkage disequilibrium (LD) with ungenotyped SNPs, gene expression database, and the evidence from other GWAS projects, when determining the potential importance of an individual SNP.Laser coagulation: Laser coagulation or laser photocoagulation surgery is used to treat a number of eye diseases and has become widely used in recent decades. During the procedure, a laser is used to finely cauterize ocular blood vessels to attempt to bring about various therapeutic benefits.Blind People's Association: The Blind People’s Association (BPA) is an organisation in India which promotes comprehensive rehabilitation of persons with all categories of disabilities through education, training, employment, community based rehabilitation, integrated education, research, publications, human resource development and other innovative means.Landolt CGross pathology: Gross pathology refers to macroscopic manifestations of disease in organs, tissues, and body cavities. The term is commonly used by anatomical pathologists to refer to diagnostically useful findings made during the gross examination portion of surgical specimen processing or an autopsy.Vascular endothelial growth factor (VEGF) IRES AComplement 2 deficiencyNeuropathy, ataxia, and retinitis pigmentosaPheophorbidase: Pheophorbidase (, phedase, PPD) is an enzyme with system name pheophorbide-a hydrolase. This enzyme catalyses the following chemical reactionFrontotemporal lobar degeneration: Frontotemporal lobar degeneration (FTLD) is a pathological process that occurs in frontotemporal dementia. It is characterized by atrophy in the frontal lobe and temporal lobe of the brain, with sparing of the parietal and occipital lobes.Congenital cataractPhotopigment: Photopigments are unstable pigments that undergo a chemical change when they absorb light. The term is generally applied to the non-protein chromophore moiety of photosensitive chromoproteins, such as the pigments involved in photosynthesis and photoreception.TetraphenylporphyrinTesticular atrophy: Testicular atrophy is a medical condition in which the male reproductive organs (the testes, which in humans are located in the scrotum) diminish in size and may be accompanied by loss of function. This does not refer to temporary changes, such as those brought on by cold.L. V. Prasad Eye InstituteDeaf white catVitreous membrane: The vitreous membrane (or hyaloid membrane or vitreous cortex) is a layer of collagen separating the vitreous humour from the rest of the eye. At least two parts have been identified anatomically.PyridiniumPlaque-forming unit: In virology, a plaque-forming unit (PFU) is a measure of the number of particles capable of forming plaques per unit volume, such as virus particles. It is a functional measurement rather than a measurement of the absolute quantity of particles: viral particles that are defective or which fail to infect their target cell will not produce a plaque and thus will not be counted.Nested case-control study: A nested case control (NCC) study is a variation of a case-control study in which only a subset of controls from the cohort are compared to the incident cases. In a case-cohort study, all incident cases in the cohort are compared to a random subset of participants who do not develop the disease of interest.Guiding Eyes for the Blind: Yorktown Heights, New YorkTumor progression: Tumor progression is the third and last phase in tumor development. This phase is characterised by increased growth speed and invasiveness of the tumor cells.QRISK: QRISK2 (the most recent version of QRISK) is a prediction algorithm for cardiovascular disease (CVD) that uses traditional risk factors (age, systolic blood pressure, smoking status and ratio of total serum cholesterol to high-density lipoprotein cholesterol) together with body mass index, ethnicity, measures of deprivation, family history, chronic kidney disease, rheumatoid arthritis, atrial fibrillation, diabetes mellitus, and antihypertensive treatment.Berk–Tabatznik syndrome: Berk–Tabatznik syndrome is a condition with an unknown cause that shows symptoms of short stature, congenital optic atrophy and brachytelephalangy. This condition is extremely rare with only two cases being found.Rod cellIntervertebral disc damage and spaceflight: Astronauts have expressed an increased incidence of back pain during spaceflight and herniated intervertebral discs (IVD) have been diagnosed upon return of Skylab and Shuttle spaceflight participants.Complement component 4: Complement component 4 is a protein involved in the complement system.Laser-induced breakdown spectroscopy: Laser-induced breakdown spectroscopy (LIBS) is a type of atomic emission spectroscopy which uses a highly energetic laser pulse as the excitation source. The laser is focused to form a plasma, which atomizes and excites samples.Meridian (perimetry, visual field): Meridian (plural: "meridians") is used in perimetry and in specifying visual fields. According to IPS Perimetry Standards 1978 (2002): "Perimetry is the measurement of [an observer's] visual functions ...Braille technology: Braille technology is assistive technology which allows blind or visually impaired people to do common tasks such as writing, browsing the Internet, typing in Braille and printing in text, engaging in chat, downloading files, music, using electronic mail, burning music, and reading documents. It also allows blind or visually impaired students to complete all assignments in school as the rest of sighted classmates and allows them take courses online.Complement control protein: The complement system distinguishes "self" from "non-self" via a range of specialized cell-surface and soluble proteins. These homologous proteins belong to a family called the "regulators of complement activation (RCA)" or "complement control proteins (CCP)".
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