Both L-leucine and D-leucine protect mice against epileptic seizures. D-leucine also terminates seizures in mice after the ... Leucines, the isomers and derivatives of leucine Leucine zipper, a common motif in transcription factor proteins This reaction ... The activation of mTOR by leucine is mediated through Rag GTPases, leucine binding to leucyl-tRNA synthetase, leucine binding ... and urinary leucine excretion were observed with leucine intakes >500 mg · kg−1 · d−1. The oxidation of l-[1-13C]-leucine ...

... (beta-leucine) is a beta amino acid and positional isomer of L-leucine which is naturally produced in humans via the ... Metabolism of L-leucine Archived 22 March 2018 at the Wayback Machine "Leucine metabolism". BRENDA. Technische Universität ... is initially catalyzed by leucine aminomutase, producing β-leucine, which is subsequently metabolized into β-ketoisocaproate (β ... A small fraction of L-leucine metabolism - less than 5% in all tissues except the testes where it accounts for about 33% - ...

... is created by the dimerization of two specific alpha helix monomers bound to DNA. The leucine zipper is formed ... A leucine zipper (or leucine scissors) is a common three-dimensional structural motif in proteins. They were first described by ... Leucine zippers are a dimerization motif of the bZIP (Basic-region leucine zipper) class of eukaryotic transcription factors. ... The ZIP domain is found in the alpha-helix of each monomer, and contains leucines, or leucine-like amino acids. These amino ...

Other names in common use include L-leucine aminotransferase, leucine 2-oxoglutarate transaminase, leucine aminotransferase, ... In enzymology, a leucine transaminase (EC 2.6.1.6) is an enzyme that catalyzes the chemical reaction L-leucine + 2-oxoglutarate ... This enzyme participates in 3 metabolic pathways: valine, leucine and isoleucine degradation, valine, leucine and isoleucine ... Leucine (methionine) transaminase of rat liver mitochondria". Biochim. Biophys. Acta. 445 (3): 622-31. doi:10.1016/0005-2744(76 ...

In enzymology, a leucine dehydrogenase (EC 1.4.1.9) is an enzyme that catalyzes the chemical reaction L-leucine + H2O + NAD+ ... This enzyme participates in valine, leucine and isoleucine degradation and valine, leucine and isoleucine biosynthesis. As of ... Other names in common use include L-leucine dehydrogenase, L-leucine:NAD+ oxidoreductase, deaminating, and LeuDH. ... Sanwal BD, Zink MW (1961). "L-Leucine dehydrogenase of Bacillus cereus". Arch. Biochem. Biophys. 94 (3): 430-435. doi:10.1016/ ...

... s are frequently involved in the formation of protein-protein interactions. Leucine-rich repeat motifs have ... Leucine zipper Kobe B, Deisenhofer J (October 1994). "The leucine-rich repeat: a versatile binding motif". Trends Biochem. Sci ... with the absence of the beta-sheets present in other leucine-rich repeats. Leucine-rich repeats are often flanked by N-terminal ... A leucine-rich repeat (LRR) is a protein structural motif that forms an α/β horseshoe fold. It is composed of repeating 20-30 ...

As mentioned in the introduction, l-photo-leucine is a synthetic derivative of the l-Leucine amino acid. l-photo-leucine is ... l-Photo-leucine is a synthetic derivative of the l-leucine amino acid that is used as its natural analog and is characterized ... l-Photo-leucine acquires its function after being exposed to UV light. This causes diazirine ring of l-photo-leucine to lose ... In the absence of the original amino acid (l-leucine) in an environment, l-photo-leucine is used just as its naturally ...

This box: view edit Except where noted otherwise, data relate to Standard temperature and pressure. Reliability of data general note. ^a ^b ^c ^d ^e CID 6106 from PubChem (Articles with short description, Short description matches Wikidata, PubChem ID (CID) not in Wikidata, Chemical data pages, Chemical data pages cleanup ...

The Leucine operon leader is an RNA element found upstream of the first gene in the Leucine biosynthetic operon. The leader ... Page for Leucine operon leader at Rfam v t e (Articles needing additional references from April 2020, All articles needing ... This structure forms when the cell has an excess of leucine and ribosome movement over the leader transcript is not impeded. ... The leader also codes for very short peptide sequence that is rich in leucine amino acid. The terminator structure is ...

... in this case leucine). The transport is not dependent on any other source of energy (for example, ATP). Leucine transporter, ... Bacterial Leucine Transporter imports leucine from the outside of the cell to the inside with the aid of two sodium ions. It is ... Leucine and alanine are the main amino acids that this protein brings across the membrane since it has a high affinity for ... Bacterial Leucine Transporter (LeuT) is a bundled twelve alpha helix protein which belongs to the family of transporters that ...

The systematic name of this enzyme class is acetyl-CoA:L-leucine N-acetyltransferase. This enzyme is also called leucine ... N-acetyl-L-leucine Thus, the two substrates of this enzyme are acetyl-CoA and L-leucine, whereas its two products are CoA and N ... In enzymology, a leucine N-acetyltransferase (EC 2.3.1.66) is an enzyme that catalyzes the chemical reaction acetyl-CoA + L- ... Isolation and properties of an enzyme synthesizing acetyl-L-leucine". J. Antibiot. 33 (8): 857-862. doi:10.7164/antibiotics. ...

... leucine-tRNA synthetase, and leucine translase. This enzyme participates in valine, leucine and isoleucine biosynthesis and ... In enzymology, a leucine-tRNA ligase (EC 6.1.1.4) is an enzyme that catalyzes the chemical reaction ATP + L-leucine + tRNALeu ... The systematic name of this enzyme class is L-leucine:tRNALeu ligase (AMP-forming). Other names in common use include leucyl- ... L-leucine, and tRNA(Leu), whereas its 3 products are AMP, diphosphate, and L-leucyl-tRNA(Leu). This enzyme belongs to the ...

... is an enzyme that in humans is encoded by the LCMT1 gene. LCMT1 has been shown to interact ... "Entrez Gene: LCMT1 leucine carboxyl methyltransferase 1". Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, ... Lee JA, Pallas DC (Oct 2007). "Leucine carboxyl methyltransferase-1 is necessary for normal progression through mitosis in ... "Purification of porcine brain protein phosphatase 2A leucine carboxyl methyltransferase and cloning of the human homologue". ...

... beta-leucine Hence, this enzyme is responsible for the conversion of L-leucine to β-leucine. This enzyme belongs to the family ... In enzymology, a leucine 2,3-aminomutase (EC 5.4.3.7) is an enzyme that catalyzes the chemical reaction (2S)-alpha-leucine ⇌ {\ ... Poston JM (1976). "Leucine 2,3-aminomutase, an enzyme of leucine catabolism". J. Biol. Chem. 251 (7): 1859-63. PMID 1270414. ... The systematic name of this enzyme class is (2S)-alpha-leucine 2,3-aminomutase. This enzyme participates in valine, leucine and ...

Leucine responsive protein, or Lrp, is a global regulator protein, meaning that it regulates the biosynthesis of leucine, as ... Leucine-Responsive+Regulatory+Protein at the U.S. National Library of Medicine Medical Subject Headings (MeSH) v t e (Articles ... de los Rios S, Perona JJ (March 2007). "Structure of the Escherichia coli leucine-responsive regulatory protein Lrp reveals a ... Baek, Chang-Ho; Wang, Shifeng; Roland, Kenneth L.; Curtiss, Roy (2009). "Leucine-Responsive Regulatory Protein (Lrp) Acts as a ...

The leucines are primarily the four isomeric amino acids: leucine, isoleucine, tert-leucine (terleucine, pseudoleucine) and ... Leucine and isoleucine belong to the proteinogenic amino acids; the others are non-natural. Including the stereoisomers, six ... L-Photo-Leucine Jeremy M. Berg, John L. Tymoczko, Lubert Stryer: Biochemie. 6 Auflage, Spektrum Akademischer Verlag, Heidelberg ... further isomers could be added: D-leucine, D-isoleucine, L-alloisoleucine, D-alloisoleucine, D-tert-leucine and D-norleucine. ...

... is a cell membrane-expressed protein. In humans it is encoded by the LRRC15 gene. It is ... "Entrez Gene: Leucine rich repeat containing 15". Gisby JS, Buang NB, Papadaki A, Clarke CL, Malik TH, Medjeral-Thomas N, ... Satoh K, Hata M, Yokota H (January 2002). "A novel member of the leucine-rich repeat superfamily induced in rat astrocytes by ... Cui J, Dean D, Wei R, Hornicek FJ, Ulmert D, Duan Z (September 2020). "Expression and Clinical Implications of Leucine-Rich ...

... hypoglycemia leucine induced; and familial infantile hypoglycemia precipitated by leucine. "Leucine-sensitive hypoglycemia of ... "OMIM Entry - # 240800 - HYPOGLYCEMIA, LEUCINE-INDUCED; LIH". www.omim.org. Retrieved 27 October 2019. "Hypoglycemia, Leucine- ... Leucine-sensitive hypoglycemia of infancy is a type of metabolic disorder. It is inherited in an autosomal dominant fashion. It ...

... is a protein that in humans is encoded by the LRRC3 gene. Leucine rich repeat GRCh38: Ensembl ... "Entrez Gene: Leucine rich repeat containing 3". Retrieved 2016-05-12. v t e (Articles with short description, Short description ...

... is a protein that in humans is encoded by the LRRC61 gene. GRCh38: Ensembl release 89: ... "Entrez Gene: Leucine rich repeat containing 61". Retrieved 2017-01-16. v t e (Articles with short description, Short ...

... (EC 2.1.1.233, leucine carboxy methyltransferase-1, LCMT1) is an ... leucine methyl ester Methylates the C-terminal leucine of phosphatase 2A. De Baere I, Derua R, Janssens V, Van Hoof C, Waelkens ... phosphatase+2A+protein)-leucine-carboxy+methyltransferase at the U.S. National Library of Medicine Medical Subject Headings ( ... Tsai ML, Cronin N, Djordjevic S (January 2011). "The structure of human leucine carboxyl methyltransferase 1 that regulates ...

... (PEPR1 and PEPR2 in Arabidopsis thaliana and Xa21 in rice) are plant cell ... PEPR 1 is a receptor kinase with extra cellular leucine rich repeat motif and functions as a receptor for AtPEPs. In addition, ... Yamaguchi Y, Pearce G, Ryan CA (June 2006). "The cell surface leucine-rich repeat receptor for AtPep1, an endogenous peptide ... membrane localized Leucine-rich repeat (LRR) receptor kinase that play critical roles in plant innate immunity. Plants have ...

Basic helix-loop-helix leucine zipper transcription factors are, as their name indicates, transcription factors containing both ... leucine+zipper+transcription+factors at the U.S. National Library of Medicine Medical Subject Headings (MeSH) v t e (Articles ... Basic helix-loop-helix and leucine zipper motifs. Examples include Microphthalmia-associated transcription factor and Sterol ...

... is a protein that in humans is encoded by the FBXL15 gene. GRCh38: Ensembl release 89 ... "Entrez Gene: F-box and leucine rich repeat protein 15". Retrieved 2018-03-21. v t e (Articles with short description, Short ...

The Leucine-Rich Repeat domain is found in three isoforms of LRRIQ1. LRRIQ1 contains 4 Leucine Rich Repeats (LRR). The LRR ... Leucine-rich repeats and IQ motif containing 1 is a protein that in humans is encoded by the LRRIQ1 gene. The protein is likely ... "LRRIQ1 leucine-rich repeats and IQ motif containing 1 [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved ... "Entrez Gene: Leucine-rich repeats and IQ motif containing 1". Retrieved 2016-03-29. Hart, Gerald W.; Akimoto, Yoshihiro (2009- ...

... is a protein that in humans is encoded by the LRRD1 gene. GRCh38: Ensembl ... "Entrez Gene: Leucine-rich repeats and death domain containing 1". Retrieved 2016-02-22. v t e (Articles with short description ...

"Entrez Gene: BZW2 basic leucine zipper and W2 domains 2". "BZW2 basic leucine zipper and W2 domains 2 [Homo sapiens (human)] - ... Basic Leucine Zipper and W2 Domain-Containing Protein 2 is a protein that is encoded by the BZW2 gene. It is a eukaryotic ... It has been found to interact with SARS-CoV-2. BZW2 is known as Basic Leucine Zipper W2 Domain-Containing Protein 2, MST017, ... As described in the name, the protein contains a leucine-zipper motif. Four "L……" repeats are present in the beginning, giving ...

... is a protein that in humans is encoded by the ANP32A gene. It is ... Acidic leucine-rich nuclear phosphoprotein 32 family member A has been shown to interact with MAP1B, TAF1A and Protein SET. ... 1997). "The cerebellar leucine-rich acidic nuclear protein interacts with ataxin-1". Nature. 389 (6654): 974-8. Bibcode: ... "Entrez Gene: ANP32A Acidic (leucine-rich) nuclear phosphoprotein 32 family, member A". Opal, Puneet; Garcia Jesus J; Propst ...

... is a protein that in humans is encoded by the LRFN4 gene. ... "Entrez Gene: Leucine rich repeat and fibronectin type III domain containing 4". Retrieved 2016-10-17. Konakahara S, Saitou M, ... Fibronectin type III domain Leucine rich repeat GRCh38: Ensembl release 89: ENSG00000173621 - Ensembl, May 2017 GRCm38: Ensembl ...

Its metabolic precursor and metabolic product in the leucine metabolic pathway are β-leucine and β-ketoisocaproyl-CoA, ... β-Ketoisocaproic acid, also known as 4-methyl-3-oxopentanoic acid, is an intermediate in the metabolism of leucine. ... Kohlmeier M (May 2015). "Leucine". Nutrient Metabolism: Structures, Functions, and Genes (2nd ed.). Academic Press. pp. 385-388 ... "Leucine metabolism". BRENDA. Technische Universität Braunschweig. Archived from the original on 17 August 2016. Retrieved 12 ...