ProstaglandinCelecoxibProstaglandin EDuctus arteriosus: In the developing fetus, the ductus arteriosus, also called the ductus Botalli, is a blood vessel connecting the pulmonary artery to the proximal descending aorta. It allows most of the blood from the right ventricle to bypass the fetus's fluid-filled non-functioning lungs.COX-3: COX-3 is an enzyme that is encoded by the PTGS1 (COX1) gene, but is not functional in humans. COX-3 is the third and most recently discovered cyclooxygenase (COX) isozyme, the others being COX-1 and COX-2.Gastric erosion: Gastric erosion occurs when the mucous membrane lining the stomach becomes inflamed. Some drugs, as tablets, can irritate this mucous membrane, especially drugs taken for arthritis and muscular disorders, steroids, and aspirin.IbuprofenGastric mucosal barrier: The gastric mucosal barrier is the property of the stomach that allows it to contain acid.MasoprocolArachidonic acidConcentration effect: In the study of inhaled anesthetics, the concentration effect is the increase in the rate that the Fa(alveolar concentration)/Fi(inspired concentration) ratio rises as the alveolar concentration of that gas is increased. In simple terms, the higher the concentration of gas administered, the faster the alveolar concentration of that gas approaches the inspired concentration.ProstacyclinBradykininAspirinVasodilation: Vasodilation (or vasodilatation) refers to the widening of blood vessels. It results from relaxation of smooth muscle cells within the vessel walls, in particular in the large veins, large arteries, and smaller arterioles.NitrobenzeneA. N. Hartley: Annie Norah Hartley (1902 – 1994), usually known simply as Norah Hartley, was a dog breeder and the first female board member of the Kennel Club.Ductus venosus: In the fetus, the ductus venosus (Arantius' duct after Julius Caesar Aranzihttp://www.whonamedit.Muscle contraction: Muscle contraction is the activation of tension-generating sites within muscle fibers. In physiology, muscle contraction does not mean muscle shortening because muscle tension can be produced without changes in muscle length such as holding a heavy book or a dumbbell at the same position.Endothelial activation: Endothelial activation is a proinflammatory and procoagulant state of the endothelial cells lining the lumen of blood vessels. It is most characterized by an increase in interactions with white blood cells (leukocytes), and it is associated with the early states of atherosclerosis and sepsis, among others.New Zealand rabbitHistamine dihydrochloride: Histamine dihydrochloride (INN, trade name Ceplene) is a salt of histamine which is used as a drug for the prevention of relapse in patients diagnosed with acute myeloid leukemia (AML). It is an FDA approvedhttp://www.PiroxicamSulfonamide (medicine): Sulfonamide or sulphonamide is the basis of several groups of drugs. The original antibacterial sulfonamides (sometimes called sulfa drugs or sulpha drugs) are synthetic antimicrobial agents that contain the sulfonamide group.Drug interaction: A drug interaction is a situation in which a substance (usually another drug) affects the activity of a drug when both are administered together. This action can be synergistic (when the drug's effect is increased) or antagonistic (when the drug's effect is decreased) or a new effect can be produced that neither produces on its own.PyrazolePeripheral edemaPhenylbutazoneNitric-oxide synthase (NAD(P)H-dependent): Nitric-oxide synthase (NAD(P)H-dependent) (, nitric oxide synthetase, NO synthase) is an enzyme with system name L-arginine,NAD(P)H:oxygen oxidoreductase (nitric-oxide-forming). This enzyme catalyses the following chemical reactionKetoprofenMethyl ethyl ketone peroxideGlutathionuria: Glutathionuria is the presence of glutathione in the urine, and is a rare inborn error of metabolism.Broad-Spectrum Chemokine Inhibitor: A Broad-Spectrum Chemokine Inhibitor or BSCI (also termed Chemotide or Somatotaxin ) is a type of experimental anti-inflammatory drug that inhibits the action of the pro-inflammatory proteins chemokines.Trachealis muscle: The trachealis muscle is a smooth muscle that bridges the gap between the free ends of C-shaped cartilages at the posterior border of the trachea, adjacent to the esophagus.Progressive osseous heteroplasia: Progressive osseous heteroplasia is a cutaneous condition characterized by cutaneous or subcutaneous ossification.Arachidonate 5-lipoxygenase: Arachidonate 5-lipoxygenase, also known as 5-lipoxygenase, 5-LOX or 5-LO, is an enzyme that in humans is encoded by the ALOX5 gene. Arachidonate 5-lipoxygenase is a member of the lipoxygenase family of enzymes.Isozyme: Isozymes (also known as isoenzymes or more generally as Multiple forms of enzymes) are enzymes that differ in amino acid sequence but catalyze the same chemical reaction. These enzymes usually display different kinetic parameters (e.Suppository: A suppository is a drug delivery system that is inserted into the rectum (rectal suppository), vagina (vaginal suppository) or urethra (urethral suppository), where it dissolves or melts and is absorbed into the blood stream. They are used to deliver both systemically and locally acting medications.TerbogrelReactive gastropathy: In gastroenterology, reactive gastropathy, also chemical gastropathy, is an abnormality in the stomach caused by chemicals, e.g.Tocolytic: Tocolytics (also called anti-contraction medications or labor repressants) are medications used to suppress premature labor (from the Greek tokos, childbirth, and lytic, capable of dissolving). They are given when delivery would result in premature birth.Vascular smooth muscleEthernet flow control: Ethernet flow control is a mechanism for temporarily stopping the transmission of data on Ethernet family computer networks. The first flow control mechanism, the PAUSE frame, was defined by the IEEE 802.Bismuth subsalicylateMacula densaProtein detoxification: Protein detoxification is the process by which proteins containing methylated arginine are broken down and removed from the body.Penetrating atherosclerotic ulcer: A penetrating atherosclerotic ulcer (PAU) is an atherosclerotic lesion that ulcerates, leading to a hematoma forming within the walls of the aorta.CimetidineSecretagogue: A secretagogue is a substance that causes another substance to be secreted. One example is gastrin,secretagogue at eMedicine Dictionary which stimulates the H/K ATPase in the parietal cells (increased gastric acid production by the stomach).