Losartan/hydrochlorothiazide: Losartan/hydrochlorothiazide is a combination drug used as an antihypertensive, consisting of losartan (an angiotensin II receptor antagonist) and hydrochlorothiazide (a diuretic).ThiazideLoop diureticLidanserin: Lidanserin (INN; ZK-33,839) is a drug which acts as a combined 5-HT2A and α1-adrenergic receptor antagonist. It was developed as an antihypertensive agent but was never marketed.AmlodipineTriamtereneHypertensionTetrazoleCombination therapy: Combination therapy or polytherapy is therapy that uses more than one medication or modality (versus monotherapy, which is any therapy taken alone). Typically, these terms refer to using multiple therapies to treat a single disease, and often all the therapies are pharmaceutical (although it can also involve non-medical therapy, such as the combination of medications and talk therapy to treat depression).AtenololAortic pressure: Central aortic blood pressure (CAP or CASP) is the blood pressure at the root of aorta. Studies have shown the importance of central aortic pressure and its implications in assessing the efficacy of antihypertensive treatment with respect to cardiovascular risk factors.AlaceprilEnalaprilLosartanPlacebo-controlled study: Placebo-controlled studies are a way of testing a medical therapy in which, in addition to a group of subjects that receives the treatment to be evaluated, a separate control group receives a sham "placebo" treatment which is specifically designed to have no real effect. Placebos are most commonly used in blinded trials, where subjects do not know whether they are receiving real or placebo treatment.ClemizolePerindopril/indapamideIndeneValine N-monooxygenase: Valine N-monooxygenase (, CYP79D1, CYP79D2) is an enzyme with system name L-valine,NADPH:oxygen oxidoreductase (N-hydroxylating). This enzyme catalyses the following chemical reactionEffervescent tablet: Effervescent or carbon tablets are tablets which are designed to break in contact with water or another liquid, releasing carbon dioxide in the process.British Pharmacopeia 2003 Rapid breakdown often may cause the tablet to dissolve into a solution, and is also often followed by a froth.IrbesartanFosinoprilCilazaprilATC code M04: ==M04A Antigout preparations==BendroflumethiazideAmbulatory blood pressure: Ambulatory Blood Pressure Monitoring (ABPM) measures blood pressure at regular intervals. It is believed to be able to reduce the white coat hypertension effect in which a patient's blood pressure is elevated during the examination process due to nervousness and anxiety caused by being in a clinical setting.Propyl benzoateEtacrynic acidLisinoprilUrinary calcium: Urinary calcium is calcium in the urine. It is termed -calcuria or -calciuria as a suffix.SpironolactoneRenin: Renin, Iran}}HypokalemiaTrans-tubular potassium gradient: The trans-tubular potassium gradient (TTKG) is an index reflecting the conservation of potassium in the cortical collecting ducts (CCD) of the kidneys. It is useful in diagnosing the causes of hyperkalemia or hypokalemia.ImidazoleMetoprololIron(II) fumarateATC code C08: ==C08C Selective calcium channel blockers with mainly vascular effects==Nitrendipine