Epigenetics of human herpesvirus latency
Varicella zoster virus (VZV) is a member of the alpha subfamily of herpesviruses and is responsible for the human diseases of ... Human herpes viruses, also known as HHVs, are part of a family of DNA viruses that cause several diseases in humans. One of the ... Human herpesviruses are all double stranded DNA viruses that enter the nucleus of the host cell. HHVs replicate in the nucleus ... Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis. Cambridge University Press. ISBN 9781139461641. Retrieved 2015-05 ...
Varicella zoster virus
... (VZV), also known as human herpesvirus 3 (HHV-3, HHV3) or Human alphaherpesvirus 3 (taxonomically), is ... Relation with other human herpes viruses is less strong, but many homologues and conserved gene blocks are still found. There ... Human herpesvirus 3 Human herpesvirus 3 [X04370=NC_001348] (HHV-3) (Varicella-zoster virus) "ICTV Taxonomy history: Human ... one of nine known herpes viruses that can infect humans. It causes chickenpox (varicella) commonly affecting children and young ...
Herpes virus
Human herpesvirus 6, the collective name for Human betaherpesvirus 6A and Human betaherpesvirus 6B Human betaherpesvirus 7 ... also called varicella-zoster virus, responsible for chickenpox and shingles Human gammaherpesvirus 4, or Epstein-Barr virus, ... Herpes virus may refer to: Any member of the large family of DNA viruses known as Herpesviridae Human herpesviruses, nine types ... of herpesviruses that can cause diseases in humans Herpes simplex virus 1 and 2, responsible for herpes simplex infections ...
Viral hepatitis
... varicella-zoster virus, human herpesvirus 6, human herpesvirus 7, and human herpesvirus 8 Orthomyxoviruses: influenza ... Anderson DR, Schwartz J, Hunter NJ, Cottrill C, Bisaccia E, Klainer AS (September 1994). "Varicella hepatitis: a fatal case in ... Tayor JM (2009). Desk Encyclopedia of Human and Medical Virology. Boston: Academic Press. p. 121. ISBN 978-0-12-375147-8. "CDC ... "National Library of Medicine » Medical Subject Headings »Virus Diseases (C02) » Hepatitis, Viral, Human (C02.440) » Scope Note ...
Orthoherpesviridae
Other human herpesviruses are human herpesvirus 6A and 6B (HHV-6A and HHV-6B), human herpesvirus 7 (HHV-7), and Kaposi's ... varicella zoster (or HHV-3; the cause of chickenpox and shingles), Epstein-Barr (EBV or HHV-4; implicated in several diseases, ... Nine herpesvirus types are known to primarily infect humans, at least five of which are extremely widespread among most human ... In addition to the herpesviruses considered endemic in humans, some viruses associated primarily with animals may infect humans ...
Infections associated with diseases
Di Luca, D; Zorzenon, M; Mirandola, P; Colle, R; Botta, GA; Cassai, E (1995). "Human herpesvirus 6 and human herpesvirus 7 in ... Sotelo, Julio; Martínez-Palomo, Adolfo; Ordoñez, Graciela; Pineda, Benjamin (2008). "Varicella-zoster virus in cerebrospinal ... JC Virus and Simian Virus 40 Infection in Humans, and Association with Human Tumors". Polyomaviruses and Human Diseases. ... 2007). "Association of Human Herpesvirus-6B with Mesial Temporal Lobe Epilepsy". PLOS Medicine. 4 (5): e180. doi:10.1371/ ...
Transverse myelitis
Varicella-zoster virus, Epstein-Barr virus, cytomegalovirus, Human herpesvirus 6 or enteroviruses) Evidence of multiple ... Human immunodeficiency virus, Human T-lymphotropic virus 1, mycoplasma, Herpes simplex virus, ... The prognosis for TM depends on whether there is improvement in 3 to 6 months. Complete recovery is unlikely if no improvement ...
Varicella vaccine
Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis. Cambridge: Cambridge University Press. ISBN 978-0521827140. PMID ... Varicella vaccine is 70% to 90% effective for preventing varicella and more than 95% effective for preventing severe varicella ... The Oka virus was initially obtained from a child with natural varicella, introduced into human embryonic lung cell cultures, ... The varicella zoster vaccine is made from the Oka/Merck strain of live attenuated varicella virus. ...
Harrison's Principles of Internal Medicine
Cytomegalovirus and Human Herpesvirus Types 6, 7, and 8 Chapter 191: Molluscum Contagiosum, Monkeypox, and Other Poxvirus ... Varicella-Zoster Virus Infections Chapter 189: Epstein-Barr Virus Infections, Including Infectious Mononucleosis Chapter 190: ... Infections Due to Human Immunodeficiency Virus and Other Human Retroviruses Chapter 196: The Human Retroviruses Chapter 197: ... In the care of suffering he needs technical skill, scientific knowledge and human understanding. He who uses these with courage ...
Oral mucosa
Kaposi Sarcoma is related to the Kaposi Sarcoma Herpes Virus (KSHV) or Human Herpes Virus (HHV-8) viral infection (3). ... Chicken Pox: A type of viral infection which is caused by Varicella Zoster Virus and presents in children. Numerous itchy ... Each human herpes virus may present differently within the oral cavity. They are more likely to affect immunocompromised ... glands are only present in their paws The majority of viral infections affecting the oral cavity are caused by the human Herpes Virus ...
Mollaret's meningitis
"Real-time PCR detection of Human Herpesvirus 1-5 in patients lacking clinical signs of a viral CNS infection". BMC Infectious ... Jhaveri, Ravi M.D.; Sankar, Raman M.D.; Yazdani, Shahram M.D.; Cherry, James D. M.D. (2003). "Varicella-zoster virus: an ... Treatment with acyclovir was successful, indicating that a herpes virus was the cause of his symptoms. Acyclovir is the ... Some patients also report frequent shingles outbreaks.[citation needed] Varicella zoster virus, which causes chickenpox and ...
Virus
Kaposi's sarcoma-associated herpesvirus and human T-lymphotropic virus. The most recently discovered human cancer virus is a ... Another, more rare, example is the varicella zoster virus, which, although causing relatively mild infections in children and ... Jordan MC, Jordan GW, Stevens JG, Miller G (June 1984). "Latent herpesviruses of humans". Annals of Internal Medicine. 100 (6 ... ISBN 978-0-7817-8215-9. Komaroff AL (December 2006). "Is human herpesvirus-6 a trigger for chronic fatigue syndrome?". Journal ...
Thymidine kinase
Genes on human chromosome 17, Genes on human chromosome 16, Pages using gallery with unknown parameters, EC 2.7.1). ... The herpesvirus thymidine kinase gene has also been used as a "suicide gene" as a safety system in gene therapy experiments, ... Sequencing the thymidine kinase gene in Herpes simplex virus and Varicella zoster virus shows the rapid genetic variability and ... Human thymidine kinase, in contrast, with its more narrow specificity, is unable to phosphorylate and activate the prodrug. In ...
Herpes simplex virus
The only human vaccines available for herpesviruses are for Varicella zoster virus, given to children around their first ... also known by their taxonomic names Human alphaherpesvirus 1 and Human alphaherpesvirus 2, are two members of the human ... Animal herpes viruses all share some common properties. The structure of herpes viruses consists of a relatively large, double- ... Davidson AJ (2007-08-16). "Comparative analysis of the genomes". Human Herpesviruses. Cambridge University Press. ISBN 978-0- ...
History of virology
De Bolle L, Naesens L, De Clercq E (January 2005). "Update on human herpesvirus 6 biology, clinical features, and therapy". ... in virus isolation and detection methods resulted in the discovery of several important human viruses including varicella ... The first human virus to be identified was the yellow fever virus. In 1881, Carlos Finlay (1833-1915), a Cuban physician, first ... Epstein-Barr virus is important in the history of viruses for being the first virus shown to cause cancer in humans. The second ...
List of periodontal diseases
... such as oral hygiene and human herpesviruses. Linear gingival erythema presents as a localized or generalized, linear band of ... The most common viral infections causing gingival lesions are herpes simplex virus type 1 and 2, and varicella-zoster virus. ... Beginning two to three weeks after first plaque formation, the established lesion is widespread in both human and animals ... 3: 99. Kofoid CA, Hinshaw HC, Johnstone HG. Animal parasites of the mouth and their relation to dental disease. J Am Dent Assoc ...
Risk factors of schizophrenia
Polio, measles, varicella-zoster, rubella, herpes simplex, maternal genital infections, Borna disease virus, and Toxoplasma ... Psychiatrists E. Fuller Torrey and R.H. Yolken have hypothesized that the latter, a common parasite in humans, contributes to ... Conejero-Goldberg C, Torrey EF, Yolken RH (March 2003). "Herpesviruses and Toxoplasma gondii in orbital frontal cortex of ... Flegr, J (2013). "Influence of latent Toxoplasma infection on human personality, physiology and morphology: Pros and cons of ...
Viral encephalitis
... equine encephalitis virus Enteroviruses Epstein-Barr virus Herpes simplex virus HIV Human herpesvirus 6 Human herpesvirus 7 ... Louis virus Tahyna virus Tick-borne encephalitis virus Varicella-zoster virus, which causes both chickenpox and shingles ... Exceptions to this include herpesviruses and the rabies virus, which travel from nerve endings to the CNS. Once in the brain, ... Although not as effective, nucleoside analogs are used for other herpesviruses as well, such as acyclovir, with possible ...
Duplodnaviria
Diseases in humans caused by herpesviruses have been recognized for much of recorded history, and person-to-person transmission ... Examples of this include the herpes simplex virus, which causes recurring infections, and the varicella zoster virus, which ... In humans, herpesviruses usually cause various epithelial diseases such as herpes simplex, chickenpox and shingles, and ... and herpesviruses are associated with a variety of diseases in animals, including humans. A common feature among viruses in ...
Realm (virology)
The relation between caudoviruses and herpesviruses is not certain, as they may either share a common ancestor or herpesviruses ... Kukhanova MK, Korovina AN, Kochetkov SN (December 2014). "Human herpes simplex virus: life cycle and development of inhibitors ... "Varicella zoster virus infection". Nat Rev Dis Primers. 1: 15016. doi:10.1038/nrdp.2015.16. PMC 5381807. PMID 27188665. O'Leary ... Herpesviruses are known to cause a variety of epithelial diseases, including herpes simplex, chickenpox and shingles, and ...
DNA virus
The relation between caudoviruses and herpesviruses is also uncertain: they may share a common ancestor or herpesviruses may be ... Kukhanova MK, Korovina AN, Kochetkov SN (December 2014). "Human herpes simplex virus: life cycle and development of inhibitors ... "Varicella zoster virus infection". Nat Rev Dis Primers. 1: 15016. doi:10.1038/nrdp.2015.16. PMC 5381807. PMID 27188665. O'Leary ... Herpesviruses are known to cause a variety of epithelial diseases, including herpes simplex, chickenpox and shingles, and ...
Rabies
Most animals can be infected by the virus and can transmit the disease to humans. Worldwide, about 99% of human rabies cases ... The most important viruses to rule out are herpes simplex virus type one, varicella zoster virus, and (less commonly) ... in particular infection with viruses such as herpesviruses, enteroviruses, and arboviruses such as West Nile virus. ... There are only a small number of recorded cases of human-to-human transmission of rabies, and all occurred through organ ...
HHV Latency Associated Transcript
Human Herpes Virus (HHV) infections. The LAT RNA is produced by genetic transcription from a certain region of the viral DNA. ... Simian varicella virus (SVV) is a Varicellovirus (a Genus of Subfamily Alphaherpesvirinae) which expresses an HHV LAT homolog ... Herpes virus may establish lifelong infection during which a reservoir virus population survives in host nerve cells for long ... Jiang Y, Inman M, Zhang Y, Posadas NA, Jones C (March 2004). "A mutation in the latency-related gene of bovine herpesvirus 1 ...
Interactome
Human (mammalian) viruses Human varicella zoster virus (VZV) Chandipura virus Epstein-Barr virus (EBV) Hepatitis C virus (HPC ... Human-HCV interactions Hepatitis E virus (HEV) Herpes simplex virus 1 (HSV-1) Kaposi's sarcoma-associated herpesvirus (KSHV) ... the pathogen-host interactomes of Hepatitis C Virus/Human (2008), Epstein Barr virus/Human (2008), Influenza virus/Human (2009 ... Goh, K. -I.; Choi, I. -G. (2012). "Exploring the human diseasome: The human disease network". Briefings in Functional Genomics ...
Virus latency
Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis. Cambridge University Press. ISBN 9780521827140. PMID 21348106 - ... In the case of varicella zoster virus, after an initial acute infection (chickenpox) the virus lies dormant until reactivated ... One example is the herpes virus family, Herpesviridae, all of which establish latent infection. Herpes virus include chicken- ... This is also seen with infections of the human papilloma virus in which persistent infection may lead to cervical cancer as a ...
Stephen Straus
He is particularly known for his research into human herpesviruses and chronic fatigue syndrome, and for his discovery of the ... varicella zoster virus (VZV) and Epstein-Barr virus (EBV). His studies included herpesvirus pathogenesis, immune responses and ... Straus is particularly known for his wide-ranging research on herpesviruses that infect humans, including herpes simplex virus ... They showed that chickenpox (varicella) and shingles (herpes zoster) are both caused by this virus. Straus also studied the ...
Vidarabine
... to be given systemically and was the first agent to be licensed for the treatment of systemic herpes virus infection in humans ... Vidarabine or 9-β-D-arabinofuranosyladenine (ara-A) is an antiviral drug which is active against herpes simplex and varicella ... Vidarabine is an antiviral, active against herpes viruses, poxviruses, rhabdoviruses, hepadnaviruses and some RNA tumour ... This results in about a 10-fold greater selectivity against Varicella Zoster Virus than ara-A, however analog of vidarabine is ...
HHV Infected Cell Polypeptide 0
Human Herpes Virus (HHV) Infected Cell Polypeptide 0 (ICP0) is a protein, encoded by the DNA of herpes viruses. It is produced ... Simian varicella virus (SVV) is a varicellovirus that, like HSV-1 and HSV-2, belongs to the alphaherpesvirinae subfamily of ... including human PML protein. HSV-1 ICP0 and several of its homologs in other herpes viruses bind to SUMO-1 in a manner similar ... The ICP0 gene and protein from HSV-1 have orthologs in related viruses from the herpes virus family. HSV-2 ICP0 is predicted to ...
Chickenpox
2007). "Chapter 65Antiviral therapy of varicella-zoster virus infections". In Arvin, Ann; et al. (eds.). Human herpesviruses : ... "Varicella-zoster vaccine", Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis, Cambridge: Cambridge University Press ... Weller TH (1997). "Varicella-herpes zoster virus". In Evans AS, Kaslow RA (eds.). Viral Infections of Humans: Epidemiology and ... ISBN 978-0-88416-458-6. Teri Shors (2011). "Herpesviruses: Varicella Zoster Virus (VZV)". Understanding Viruses (2nd ed.). ...
Central nervous system viral disease
Treatments of proven efficacy are currently limited mostly to herpes viruses and human immunodeficiency virus. The herpes virus ... sclerosing panencephalitis by Measles virus Progressive multifocal leukoencephalopathy Rabies Tick-borne encephalitis Varicella ... Human Immunodeficiency Virus Infection (HIV) is treated by using a combination of medications to fight against the HIV ... New herpes virus drugs include viral helicase-primase and terminase inhibitors. A promising new area of research involves ...
Cytomegalovirus
... human herpesvirus 6 and human betaherpesvirus 7). It is also related to other herpesviruses within the Alphaherpesvirinae ... subfamily, which includes herpes simplex viruses 1 and 2 and varicella-zoster virus, and the Gammaherpesvirinae subfamily, ... It is thus longer than all other human herpesviruses and one of the longest genomes of all human viruses in general. It has the ... Humans and other primates serve as natural hosts. The 11 species in this genus include human betaherpesvirus 5 (HCMV, human ...
Varicellovirus
Humans and mammals serve as the natural host. Only one member of the Varicellovirus genus, Varicella zoster virus (HHV-3) ... "Evolution of the herpesviruses". Vet. Microbiol. 86 (1-2): 69-88. doi:10.1016/s0378-1135(01)00492-8. PMID 11888691. Wikimedia ... Humans and other mammals serve as natural hosts. There are 19 species in this genus. Diseases associated with this genus ... infects Homo sapiens (humans). "Virus Taxonomy: 2022 Release". International Committee on Taxonomy of Viruses (ICTV). March ...