Glutathione transferases play a key role in catalyzing such reactions. Bacterial glutathione transferases of all classes are ... Without glutathione in its reduced form, glutathione transferases are not able to utilize it as a substrate in redox reactions ... Bacterial glutathione transferases (GSTs; EC 2.5.1.18) are part of a superfamily of enzymes that play a crucial role in ... Bacterial glutathione transferases are not detected in anaerobic bacteria or archaea. These antioxidant enzymes are a part of ...
Affinity chromatography Bacterial glutathione transferase Glutathione S-transferase Mu 1 Glutathione S-transferase, C-terminal ... Overview of Glutathione S-Transferases Glutathione+S-Transferase at the U.S. National Library of Medicine Medical Subject ... "Glutathione S-transferase pull-down assays using dehydrated immobilized glutathione resin". Analytical Biochemistry. 322 (2): ... "Three-dimensional structure of Escherichia coli glutathione S-transferase complexed with glutathione sulfonate: catalytic roles ...
... is an enzyme that in humans is encoded by the GSTA1 gene. Cytosolic and membrane-bound forms of ... "Entrez Gene: GSTA1 glutathione S-transferase A1". Knapen, MF; Mulder, TP; Bisseling, JG; Penders, RH; Peters, WH; Steegers, EA ... This gene encodes a glutathione S-transferase belonging to the alpha class. The alpha class genes, located in a cluster mapped ... 1988). "Human glutathione S-transferases. The Ha multigene family encodes products of different but overlapping substrate ...
... (gene name GSTM1) is a human glutathione S-transferase. Cytosolic and membrane-bound forms of ... "Entrez Gene: GSTM1 glutathione S-transferase M1". Engel LS, Taioli E, Pfeiffer R, Garcia-Closas M, Marcus PM, Lan Q, et al. ( ... PDBe-KB provides an overview of all the structure information available in the PDB for Human Glutathione S-transferase Mu 1 v t ... This gene encodes a cytoplasmic glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in ...
... is an enzyme that in humans is encoded by the MGST1 gene. The MAPEG family (Membrane- ... Cholon A, Giaccia AJ, Lewis AD (1992). "What role do glutathione S-transferases play in the cellular response to ionizing ... DeJong JL, Mohandas T, Tu CP (1990). "The gene for the microsomal glutathione S-transferase is on human chromosome 12". ... DeJong JL, Morgenstern R, Jörnvall H (1988). "Gene expression of rat and human microsomal glutathione S-transferases". J. Biol ...
... is a structural domain of glutathione S-transferase (GST). GST conjugates reduced ... "Three-dimensional structure of Escherichia coli glutathione S-transferase complexed with glutathione sulfonate: Catalytic roles ... Glutathione S-transferases form homodimers, but in eukaryotes can also form heterodimers of the A1 and A2 or YC1 and YC2 ... In eukaryotes, glutathione S-transferases (GSTs) participate in the detoxification of reactive electrophilic compounds by ...
... a tool to measure the cellular glutathione redox potential Glutathione-ascorbate cycle Bacterial glutathione transferase ... Glutathione facilitates metabolism of xenobiotics. Glutathione S-transferase enzymes catalyze its conjugation to lipophilic ... Glutathione exists in reduced (GSH) and oxidized (GSSG) states. The ratio of reduced glutathione to oxidized glutathione within ... Glutathione enhances the function of citrulline as part of the nitric oxide cycle. It is a cofactor and acts on glutathione ...
Habig WH, Pabst MJ, Jakoby WB (1974). "Glutathione S-transferases. The first enzymatic step in mercapturic acid formation". J ... The molecule is conjugated to a single molecule of reduced glutathione which then absorbs at 340 nm. Affinity of CDNB for each ...
"Entrez Gene: GSTA3 glutathione S-transferase A3". Johansson AS, Mannervik B (2001). "Human glutathione transferase A3-3, a ... Glutathione S-transferase A3 is an enzyme that in humans is encoded by the GSTA3 gene. Cytosolic and membrane-bound forms of ... This gene encodes a glutathione S-transferase belonging to the alpha class genes that are located in a cluster mapped to ... Suzuki T, Johnston PN, Board PG (Mar 1994). "Structure and organization of the human alpha class glutathione S-transferase ...
Glutathione S-transferase P is an enzyme that in humans is encoded by the GSTP1 gene. Glutathione S-transferases (GSTs) are a ... "Entrez Gene: GSTP1 glutathione S-transferase pi". Cumming RC, Lightfoot J, Beard K, Youssoufian H, O'Brien PJ, Buchwald M (July ... The glutathione S-transferase pi gene (GSTP1) is a polymorphic gene encoding active, functionally different GSTP1 variant ... Wang T, Arifoglu P, Ronai Z, Tew KD (15 June 2001). "Glutathione S-transferase P1-1 (GSTP1-1) inhibits c-Jun N-terminal kinase ...
Glutathione S-transferase theta-1 is an enzyme that in humans is encoded by the GSTT1 gene. Glutathione S-transferase (GST) ... "Entrez Gene: GSTT1 glutathione S-transferase theta 1". v t e (Articles with short description, Short description matches ... "Chromosomal localization of the gene for the human theta class glutathione transferase (GSTT1)". Genomics. 33 (1): 121-3. doi: ... theta 1 (GSTT1) is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of ...
... also possesses a glutathione S-transferase. Cunninghamella elegans is a microbial model of mammalian ... Cytochrome P450 monooxygenase, aryl sulfotransferase, glutathione S-transferase, UDP-glucuronosyltransferase, UDP- ... expression and characterization of a novel class glutathione S-transferase from the fungus Cunninghamella elegans". Biochemical ...
Glutathione S-transferase omega-1 is an enzyme that in humans is encoded by the GSTO1 gene. This gene encodes a member of the ... "Entrez Gene: GSTO1 glutathione S-transferase omega 1". Whitbread AK, Masoumi A, Tetlow N, Schmuck E, Coggan M, Board PG (2005 ... 2004). "Glutathione S-transferase omega-1 modifies age-at-onset of Alzheimer disease and Parkinson disease". Hum. Mol. Genet. ... 2007). "Glutathione S-transferase omega in the lung and sputum supernatants of COPD patients". Respir. Res. 8 (1): 48. doi: ...
Glutathione S-transferase M3 (brain), also known as GSTM2, is an enzyme which in humans is encoded by the GSTM99 gene. ... "Entrez Gene: GSTM3 glutathione S-transferase M3 (brain)". Campbell E, Takahashi Y, Abramovitz M, Peretz M, Listowsky I (June ... This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the ... Gough AC, Zhong S, Wolf CR, Spurr NK (1993). "Chromosome assignment of the human glutathione S-transferase mu 3 gene (GSTM3) to ...
Microsomal glutathione S-transferase 2 is an enzyme that in humans is encoded by the MGST2 gene. The MAPEG (Membrane-Associated ... "Entrez Gene: MGST2 microsomal glutathione S-transferase 2". Jakobsson PJ, Morgenstern R, Mancini J, et al. (2000). "Membrane- ... 2001). "Human umbilical vein endothelial cells generate leukotriene C4 via microsomal glutathione S-transferase type 2 and ... 2006). "Systematic evaluation of association between the microsomal glutathione S-transferase 2 common variation and psoriasis ...
Glutathione S-transferase theta-2 is an enzyme that in humans is encoded by the GSTT2 gene. Glutathione S-transferase (GSTs) ... GSTT2 glutathione S-transferase theta 2". Hussey AJ, Hayes JD (1992). "Characterization of a human class-Theta glutathione S- ... 1996). "The distribution of theta-class glutathione S-transferases in the liver and lung of mouse, rat and human". Biochem. J. ... de Bruin WC, Wagenmans MJ, Peters WH (2000). "Expression of glutathione S-transferase alpha, P1-1 and T1-1 in the human ...
Glutathione S-transferase omega-2 is an enzyme that in humans is encoded by the GSTO2 gene. Model organisms have been used in ... Morari EC, Lima AB, Bufalo NE, Leite JL, Granja F, Ward LS (Aug 2006). "Role of glutathione-S-transferase and codon 72 of P53 ... "Entrez Gene: GSTO2 glutathione S-transferase omega 2". Gerdin AK (2010). "The Sanger Mouse Genetics Programme: high throughput ... Leite JL, Morari EC, Granja F, Campos GM, Guilhen AC, Ward LS (Mar 2007). "Influence of the glutathione s-transferase gene ...
Microsomal glutathione S-transferase 3 is an enzyme that in humans is encoded by the MGST3 gene. The MAPEG (Membrane-Associated ... 2003). "Evaluation of the microsomal glutathione S-transferase 3 (MGST3) locus on 1q23 as a Type 2 diabetes susceptibility gene ... "Entrez Gene: MGST3 microsomal glutathione S-transferase 3". "Salmonella infection data for Mgst3". Wellcome Trust Sanger ... "Identification and characterization of a novel microsomal enzyme with glutathione-dependent transferase and peroxidase ...
Glutathione S-transferase Zeta 1 (also known as maleylacetoacetate isomerase) is an enzyme that in humans is encoded by the ... Glutathione S-transferase Zeta 1 (GSTZ1) has a predominantly hydrophobic dimer, just like many other GST members. It is ... Board PG, Baker RT, Chelvanayagam G, Jermiin LS (Dec 1997). "Zeta, a novel class of glutathione transferases in a range of ... "Entrez Gene: GSTZ1 glutathione transferase zeta 1 (maleylacetoacetate isomerase)". Polekhina G, Board PG, Blackburn AC, Parker ...
... can induce the enzyme glutathione S-transferase (GST). GST has been suggested to protect cells against oxidative ... Myricetin's pro-oxidative capabilities can also be seen in its ability to act as an inhibitory agent against glutathione ... reductase, which is responsible for regenerating glutathione, a scavenger of free radicals and peroxides. Myricetin is also ...
Soybeans naturally have a high tolerance to fomesafen, via metabolic disposal by glutathione S-transferase. As a result, soy is ... "Glutathione transferase activities toward herbicides used selectively in soybean". Pesticide Science. Wiley. 51 (2): 213-222. ...
Soybeans naturally have a high tolerance to acifluorfen and its salts, via metabolic disposal by glutathione S-transferase. It ... "Glutathione transferase activities toward herbicides used selectively in soybean". Pesticide Science. Wiley. 51 (2): 213-222. ...
... and bioinformatics studies of the human Kappa-class glutathione transferase predict a novel third glutathione transferase ... Glutathione S-transferase kappa 1 (GSTK1) is an enzyme that in humans is encoded by the GSTK1 gene which is located on ... It belongs to the superfamily of enzymes known as glutathione S-transferase (GST), which are mainly known for cellular ... Li J, Xia Z, Ding J (Sep 2005). "Thioredoxin-like domain of human kappa class glutathione transferase reveals sequence homology ...
Plants use glutathione transferases as a means to segregate toxic metals from the rest of the cell. These glutathione ... Terminal transferase is one of the few DNA polymerases that can function without an RNA primer. The family of glutathione ... Glutathione transferases are currently being explored as targets for anti-cancer medications due to their role in drug ... Further, glutathione transferase genes have been investigated due to their ability to prevent oxidative damage and have shown ...
Protein tag Fluorescent glucose biosensors Glutathione S-transferase Duan, Xiaoqun; Hall, Jason A; Nikaido, Hiroshi; Quiocho, ...
... or glutathione S-transferase II) is an enzyme that converts leukotriene A4 and glutathione to create leukotriene C4. This is a ... This protein is remotely related to microsomal glutathione S-transferase. The MAPEG (Membrane-Associated Proteins in Eicosanoid ... a homodimeric glutathione S-transferase composed of 18-kDa subunits". Proc. Natl. Acad. Sci. U.S.A. 90 (5): 2015-9. Bibcode: ... 2000). "Membrane-associated proteins in eicosanoid and glutathione metabolism (MAPEG). A widespread protein superfamily". Am. J ...
Shi, B.; Stevenson, R.; Campopiano, D. J.; Greaney, M. F. (Jul 2006). "Discovery of glutathione S-transferase inhibitors using ...
FMO4 (vimentin/dimethylalanine monooxygenase 4) and GSTM4 (glutathione transferase M4). The expression of Class III β-tubulin ...
Kotb, Magd A. (March 2015). "Evidence of Disruption of p53 and Glutathione S Transferase Pi in Extrahepatic Biliary Atresia in ... The babies have homozygous deficiency of glutathione S transferase (GST) M1. The aflatoxin damaged liver cells and bile duct ... Kotb, Magd A (March 2015). "Glutathione S Transferase M1 Polymorphism in Extrahepatic Biliary Atresia" (PDF). The Medical ... proven to be as a result of aflatoxin induced cholangiopathy acquired prenatally in infants who have glutathione S transferase ...
"Incorporation of Tellurocysteine into Glutathione Transferase Generates High Glutathione Peroxidase Efficiency". Angewandte ... When incorporated into glutathione transferase, tellurocysteine efficiently inhibited aminoacylation and increased the ... efficiency of glutathione peroxidase. L-Tellurocystine has been prepared in low yield from a protected form of 3-iodoalanine. ...