Primordial germ cells, germ cells that still have to reach the gonads (also known as PGCs, precursor germ cells or gonocytes) ... A germ cell is any cell that gives rise to the gametes of an organism that reproduces sexually. In many animals, the germ cells ... The somatic cells on the path of germ cells provide them attractive, repulsive, and survival signals. But germ cells also send ... This means that they can differentiate in any cell type in the body and thus germ cells. Specification of primordial germ cells ...

Male germ-line stem cells divide asymmetrically to give one stem cell and a spermatogonia cell (unspecialised male germ cell) ... Germ cell nest breakdown involves the degeneration of many germ cell nuclei and the invasion of pre-granulosa cells into the ... In the germ cell nest, one germ cell matures into an oocyte whereas others act as 'nurse cells', transferring their contents ... In mammals, germ cells form syncytia of hundreds of germ cells interconnected by intercellular bridges. As they share a common ...

... (GCT) is a neoplasm derived from germ cells. Germ-cell tumors can be cancerous or benign. Germ cells normally ... Childhood Extracranial Germ Cell Tumors Extragonadal Germ Cell Tumors Ovarian Germ Cell Tumors Packer RJ, Cohen BH, Cooney K, ... The nongerminomatous or nonseminomatous germ-cell tumors (NGGCT, NSGCT) include all other germ-cell tumors, pure and mixed. The ... International Germ Cell Cancer Collaborative Group (February 1997). "International Germ Cell Consensus Classification: a ...

GCNH is expressed mainly in the germ cells of gonads and is involved in the regulation of embryogenesis and germ cell ... The germ cell nuclear factor (GCNF), also known as RTR (retinoid receptor-related testis-associated receptor) or NR6A1 (nuclear ... Lan ZJ, Chung AC, Xu X, DeMayo FJ, Cooney AJ (Dec 2002). "The embryonic function of germ cell nuclear factor is dependent on ... Kapelle M, Krätzschmar J, Husemann M, Schleuning WD (May 1997). "cDNA cloning of two closely related forms of human germ cell ...

Primordial germ cell (PGC) migration is the process of distribution of primordial germ cells throughout the embryo during ... Down-regulation will result in reduced cell-cell adhesion which allows the germ cells to separate and begin the migration ... Coffman, Clark R. (May 2003). "Cell migration and programmed cell death of Drosophila germ cells". Annals of the New York ... the germ cells move towards the somatic gonadal precursor cells and associate with them. These two associated cell types then ...

Ovarian Germ Cell Tumor Extragonadal Germ Cell Tumor Cancer.net: Germ Cell Tumor include extracranial germ cell tumor ... An extracranial germ cell tumor (EGCT) occurs in the abnormal growth of germ cells in the gonads (testes or ovaries) and the ... "Mixed Germ Cell Tumor - American Urological Association". www.auanet.org. Retrieved 2019-05-29. "Extracranial Germ Cell Tumor ... Shaikh F, Hale J (2013-08-03), "Clinical Treatment of Extracranial Pediatric Germ Cell Tumors", Pediatric Germ Cell Tumors, ...

... (OGCTs) are heterogeneous tumors that are derived from the primitive germ cells of the embryonic gonad ... OGCT is caused mainly due to the formation of malignant cancer cells in the primordial germ cells of the ovary. The exact ... In order to heal the tissue and replace the damage, the cells undergoes cell division. Each time the cell divides, there is a ... Wang Y, Yang JX, Yu M, Cao DY, Shen K (2018). "Malignant mixed ovarian germ cell tumor composed of immature teratoma, yolk sac ...

... s are tumors that derive from germ cell rest remnants in the mediastinum. Germ cell tumors most ... They are much less common than germ cell tumors arising in the testes, and account for only 1 to 5% of all germ cell neoplasms ... "Mediastinal Germ Cell Tumors". Semin Respir Crit Care Med. 18 (4): 383-392. doi:10.1055/s-2007-1009353. "Mediastinal Germ Cell ... Others hypothesize a widespread distribution of germ cells to multiple sites during normal embryogenesis, with these cells ...

... (GCNIS) represents the precursor lesion for many types of testicular germ cell tumors. The term ... Not all germ cell tumors (GCTs) arise from intratubular germ cell neoplasia. The following testicular GCTs do not arise from ... Chemotherapy used for metastatic germ cell tumours may also eradicate GCNIS. Carcinoma in situ Germ cell tumor ITGCN. H&E stain ... Almost all invasive germ cell tumours of the testis in adults Fifty percent of patients with GCNIS developed invasive germ cell ...

... cell Pneumocyte Type I cell Type II cell Club cell Goblet cell Pulmonary neuroendocrine cell Enteroendocrine cell G cell Delta ... Hepatic stellate cell Cholecystocyte Centroacinar cell Pancreatic stellate cell alpha cell beta cell delta cell PP cell (F cell ... Podocyte Kidney proximal tubule brush border cell Sertoli cell Leydig cell Granulosa cell Peg cell Germ cells (which migrate ... cell Parafollicular cell Parathyroid gland Parathyroid chief cell Oxyphil cell Urothelial cell Germ layer List of distinct cell ...

Germ cell Histogenesis Neurulation List of human cell types derived from the germ layers Gilbert, Scott F (2003). "The ... A germ layer is a primary layer of cells that forms during embryonic development. The three germ layers in vertebrates are ... Through cell signaling cascades and interactions with the ectodermal and endodermal cells, the mesodermal cells begin the ... "Pluripotency Factors in Embryonic Stem Cells Regulate Differentiation into Germ Layers". Cell. 145 (6): 875-889. doi:10.1016/j. ...

Germ cells). ... Through circulation it is transported to the follicle cells ... Frontiers in Cell and Developmental Biology. 8: 593613. doi:10.3389/fcell.2020.593613. PMC 7901893. PMID 33634094. Hurd H (2003 ...

Germ Cells. Cold Spring Harbor Laboratory Press, ISBN 9781936113514 Sassone-Corsi, Paolo; Christen, Yves.,(2012), Epigenetics, ... Cell. 134 (2): 329-340. doi:10.1016/j.cell.2008.07.002. ISSN 0092-8674. PMC 3526943. PMID 18662547. Cheung, Peter; Allis, C. ... Cell. 125 (3): 497-508. doi:10.1016/j.cell.2006.03.033. ISSN 0092-8674. PMID 16678094. S2CID 5968161. Nakahata, Yasukazu; ... As such, AP-1 has a significant role in the cell cycle. Circadian biology research In 2006, Sassoni-Corsi illuminated the role ...

September 2004). "European consensus on diagnosis and treatment of germ cell cancer: a report of the European Germ Cell Cancer ... Germ cell cancer". Archived from the original on 2012-04-26. W. Albrecht; et al. (2004). "Testicular tumor markers: Corner- ... stones in the management of malignant germ cell tumors" (PDF). J Lab Med. 28 (2): 109-115. doi:10.1515/labmed.2004.018. S2CID ... Cell Biol. 116 (3): 799-807. doi:10.1083/jcb.116.3.799. PMC 2289307. PMID 1730777. Micanovic R, Gerber LD, Berger J, Kodukula K ...

Michael Ashburner (May 27, 2013). "Nebenkern (Gene Ontology term)". (Germ cells, Drosophila). ...

There are three general types of cells: germ cells, somatic cells, and stem cells. Germ cells lead to the production of gametes ... stem cell are undifferentiated cells which can develop into a specialized cell and are the earliest type of cell in a cell ... and fungi whose germ cells are derived from prior somatic cells as opposed to stem cells. The Weismann barrier is essential to ... as in unicellular ones the purposes of somatic and germ cells are consolidated in one cell. All organisms with germ-soma ...

Jamnongjit, Michelle; Hammes, Stephen R. (August 2005). "Oocyte maturation: The coming of age of a germ cell". Seminars in ... Cell Biology and Translational Medicine, Volume 8: Stem Cells in Regenerative Medicine, Cham: Springer International Publishing ... Oocytes are immature egg cells that develop to maturity within a follicle in the ovary. Oocyte abnormalities can occur due to ... The germinal vesicle breaks down and spindles assemble as homologous chromosomes align the cell's equator for the first meiotic ...

... whereas nongerminomatous germ-cell tumors display a variety of differentiation. Like other germ-cell tumors, germinomas can ... Microscopic examination typically reveals uniform cells that resemble primordial germ cells. Typically, the stroma contains ... As with other germ-cell tumors (GCTs) occurring outside the gonads, the most common location of intracranial germinoma is on or ... Nongerminomatous germ-cell tumors may be associated with increased markers such as alpha-fetoprotein with yolk sac tumors, as ...

oskar plays role in recruiting other germ line genes to the germ plasm for PGC (primordial germ cell) specification. oskar mRNA ... meaning that the P granules play a role in the cell cycle of germ cells. It is still unclear exactly how the nuclear granules ... These ribonucleoprotein granules are found in every species' germ line cells. Although they are mobile, they typically localize ... September 2018). "Drosophila primordial germ cells". eLife. 7. doi:10.7554/eLife.37949. PMC 6191285. PMID 30260314. Wang JT, ...

... s are the most common type of germ cell tumors (both benign and malignant) diagnosed in neonates, ... Rescorla FJ (March 1999). "Pediatric germ cell tumors". Semin Surg Oncol. 16 (2): 144-58. doi:10.1002/(SICI)1098-2388(199903)16 ...

In 2003 Extavour did a study at Cambridge University on the mechanisms of germ cell formation that showed animal germ cells ... She is known for demonstrating that germ cells engage in cell to cell competition before becoming a gamete, which indicates ... Derivation of male germ cells from induced pluripotent stem cells by inducers: A review "NSF Award Search: Award#0955517 - RCN ... An embryonic cell receives chemical signals from neighboring cells that activate (or repress) the genes that allow for germ- ...

"Germ Cell" of interdisciplinary neuroscience". Clinical Neuropathology. 27 (6): 439-443. doi:10.5414/NPP27439. ISSN 0722-5091. ... A great deal of study on sensory organs and the function of nerve cells was conducted by British physiologist Keith Lucas and ... Langley J.N. (1905). "On the reaction of cells and of nerve-endings to certain poisons, chiefly as regards the reaction of ... Langley, J. N. (1898-07-26). "On the Union of Cranial Autonomic (Visceral) Fibres with the Nerve Cells of the Superior Cervical ...

Blastocyst or parthenogenetic split blastocyst obtained by somatic cell nuclear transfer technology; or Germ cells voluntarily ... Stem cell laws and policy in Iran Dennis, Carina (2002). "China: Stem cells rise in the East". Nature. 419 (6905): 334-6. doi: ... Chinese law, Stem cells, Biotechnology law, Stem cell research, Medical law, Science and technology in China). ... Stem cell research in China thus is unlikely ever to be prone to the intense Christian moral values in the West, especially so ...

Meiosis is the general process in eukaryotic organisms by which germ cells are formed, and it is likely an adaptation for ... "Ovarian Germ Cell Tumors Treatment". National Cancer Institute. 1980-01-01. Retrieved 2017-12-01. Seiden, Michael (2015). " ... "Chocolate cysts from ovarian follicles".{{cite web}}: CS1 maint: multiple names: authors list (link) "Treatment for Germ Cell ... Follicular cells are flat epithelial cells that originate from surface epithelium covering the ovary. They are surrounded by ...

... germ cells and embryonal cells. Teratomas of embryonic origin are congenital; teratomas of germ cell origin may or may not be ... not germ cell) malignancy such as leukemia, carcinoma, or sarcoma. A teratoma may contain elements of other germ cell tumors, ... They are a type of germ cell tumor (a tumor that begins in the cells that give rise to sperm or eggs). They are divided into ... Teratomas derived from germ cells occur in the testicle and ovaries. Teratomas derived from embryonic cells usually occur on ...

... tumors are not considered a subtype of seminoma and unlike other germ cell tumours do not arise from intratubular germ cell ... About half of germ cell tumors of the testicles are seminomas. Treatment usually requires removal of one testicle. However, ... This is about 5 to 10 years older than men with other germ cell tumors of the testes. In most cases, they produce masses that ... A seminoma is a germ cell tumor of the testicle or, more rarely, the mediastinum or other extra-gonadal locations. It is a ...

PARP1 is over-expressed in tyrosine kinase-activated leukemias, in neuroblastoma, in testicular and other germ cell tumors, and ... The more receptors a cell has that are tuned to the message, the more the cell will respond to it. Receptors are created, or ... This process is illustrated by the insulin receptor sites on target cells, e.g. liver cells, in a person with type 2 diabetes. ... Over time, this self-induced loss of target cell receptors for insulin reduces the target cell's sensitivity to the elevated ...

... a rachis is the central cell-free core or axis of the gonadal arm of both adult males and hermaphrodites where the germ cells ... Germ Cell Development in C. elegans. Springer. p. 11. ISBN 978-1-4614-4015-4. Retrieved 6 August 2013. (Articles with short ...

For instance, at least 36 DNA repair enzymes, when mutationally defective in germ line cells, cause increased risk of cancer ( ... In asthma PARP1 facilitates recruitment and function of immune cells, including CD4+ T-cells, eosinophils, and dendritic cells ... July 2013). "PARP expression in germ cell tumours". Journal of Clinical Pathology. 66 (7): 607-12. doi:10.1136/jclinpath-2012- ... Initially, overactivation of the enzyme was linked to apoptotic cell death but later, PARP1-mediated cell death turned out to ...

PARP1 is over-expressed in tyrosine kinase-activated leukemias, in neuroblastoma, in testicular and other germ cell tumors, and ... Gagnon KT, Li L, Chu Y, Janowski BA, Corey DR (2014). "RNAi factors are present and active in human cell nuclei". Cell Rep. 6 ( ... "PARP expression in germ cell tumours". J. Clin. Pathol. 66 (7): 607-612. doi:10.1136/jclinpath-2012-201088. PMID 23486608. ... of non-small-cell lung cancers; promoter hypermetylation of ATM occurs in 47% of non-small-cell lung cancers; promoter ...