Tiling arrays provide an unbiased tool to investigate protein binding, gene expression and gene structure on a genome-wide ... For Affymetrix chips, the model-based analysis of tiling array (MAT) or hypergeometric analysis of tiling-arrays (HAT) are ... The method of sequencing cDNA to find transcribed genes also runs into problems, such as failing to detect rare or very short ... Another popular use of tiling arrays is in finding expressed genes. Traditional methods of gene prediction for annotation of ...

... dedicated array for analysis of all protease, nonproteolytic homolog, and inhibitor gene transcripts in human and mouse. Curr. ... A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae. Nature 403,623- 627 (2000). Ito T., Chiba ... Again, total RNA is extracted and used to generate cDNA for PCR amplification. As long as there is a specific primer for a ... a microarray can handle parallel analysis of multiple genes while qRT-PCR must amplify one mRNA for analysis at a time. It also ...

An autoantigen in anaplastic large cell lymphoma identified by protein array analysis". J Proteomics. 75 (17): 5279-5292. doi: ... 2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome ... An autoantigen in anaplastic large cell lymphoma identified by protein array analysis". J Proteomics. 75 (17): 5279-5292. doi: ... 2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci ...

Perform microarray experiments - DNA microarray with oligo and cDNA primers, SNP arrays, protein arrays, etc. Input Expression ... lower expression of most genes in the gene set correlates with higher values of the phenotype y Data from Oligo or cDNA arrays ... Protein complex enrichment analysis tool (COMPLEAT) provides similar enrichment analysis at the level of protein complexes. The ... Microarray analysis techniques are used in interpreting the data generated from experiments on DNA (Gene chip analysis), RNA, ...

... and gene expressions. The PET library is generated using full length cDNAs, so the ditags represent the 5' capped and the 3' ... "Gene expression analysis of plant host-pathogen interactions by SuperSAGE". Proceedings of the National Academy of Sciences of ... It is a genome-wide strategy for finding de novo long-range interactions between DNA elements bound by protein factors. The ... The advantage over chip hybridization (ChIP-Chip) is that hybridization tiling arrays do not have the statistical sensitivity ...

Genuine alternative splicing occurs in both protein-coding genes and non-coding genes to produce multiple products (proteins or ... The array is then probed with labeled cDNA from tissues of interest. The probe cDNAs bind to DNA from the exons that are ... In microarray analysis, arrays of DNA fragments representing individual exons (e.g. Affymetrix exon microarray) or exon/exon ... The gene Tra encodes a protein that is expressed only in females. The primary transcript of this gene contains an intron with ...

The process of measuring gene expression via cDNA is called expression analysis or expression profiling. Applications include: ... The original nucleic acid arrays were macro arrays approximately 9 cm × 12 cm and the first computerized image based analysis ... or DNA/RNA bound to a particular protein which is immunoprecipitated (ChIP-on-chip) for epigenetic or regulation studies. In ... Weighted gene co-expression network analysis is widely used for identifying co-expression modules and intramodular hub genes. ...

Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer. ... This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are ... each from adult human normal and osteoarthritic cartilage cDNA libraries". Osteoarthritis and Cartilage. 9 (7): 641-53. doi: ... Frizzled-10 (Fz-10) is a protein that in humans is encoded by the FZD10 gene. Fz-10 has also been designated as CD350 (cluster ...

G2 and S phase-expressed protein 1 is an enzyme that in humans is encoded by the GTSE1 gene. The protein encoded by this gene ... 2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci ... 2005). "Examples of the complex architecture of the human transcriptome revealed by RACE and high-density tiling arrays". ... 2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome ...

V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1". DNA ... "Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins". BMC ... Ribosomal RNA processing protein 1 homolog B is a protein encoded by RRP1B gene which is located on Chromosome 21. GRCh38: ... "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nature Biotechnology ...

Potassium voltage-gated channel subfamily H member 7 is a protein that in humans is encoded by the KCNH7 gene. The protein ... 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci ... 2007). "Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening ... Genes on human chromosome 2, Ion channels, All stub articles, Membrane protein stubs). ...

... is a protein which in humans is encoded by the SCG2 gene. The protein encoded by this gene is a member of the chromogranin/ ... 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci ... 2007). "Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening ... 2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome ...

Burkitt lymphoma Cancer Candidate gene Capillary array Carcinogen Carcinoma Carrier Carrier testing Cat coat genetics cDNA cDNA ... genes Prophage Prophase Prophylactic surgery Proplastid Propositus Prostate cancer Protease Protein Protein product Protein ... Ligase Line Linear tetrad Linkage Linkage analysis Linkage equilibrium Linkage group Linkage map Linking number Locus Lod score ... Gene interaction Gene library Gene locus Gene map Gene mapping Gene markers Gene mutation Gene orders Gene pair Gene pool Gene ...

Filippov V, Solovyev V, Filippova M, Gill SS (March 2000). "A novel type of RNase III family proteins in eukaryotes". Gene. 245 ... cDNA structure, expression analysis, and chromosomal location". BMC Genomics. 3 (1): 26. doi:10.1186/1471-2164-3-26. PMC 122089 ... "Validation of RNAi Silencing Efficiency Using Gene Array Data shows 18.5% Failure Rate across 429 Independent Experiments". ... Filippov V, Solovyev V, Filippova M, Gill SS (March 2000). "A novel type of RNase III family proteins in eukaryotes". Gene. 245 ...

In 1961, it was demonstrated that when a gene encodes a protein, three sequential bases of a gene's DNA specify each successive ... cDNA). This cDNA is then hybridized to the fragments on the array and visualization of the hybridization can be done. Since ... Tarca AL, Romero R, Draghici S (August 2006). "Analysis of microarray experiments of gene expression profiling". American ... Proteins in the assay bind Coomassie blue in about 2 minutes, and the protein-dye complex is stable for about an hour, although ...

1998). "A method for global protein expression and antibody screening on high-density filters of an arrayed cDNA library". ... N-terminal EF-hand calcium-binding protein 3 is a protein that in humans is encoded by the NECAB3 gene. The protein encoded by ... 2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci ... "Entrez Gene: APBA2BP amyloid beta (A4) precursor protein-binding, family A, member 2 binding protein". Human NECAB3 genome ...

... "cDNA cloning and expression analysis of new members of the mammalian F-box protein family". Genomics. 67 (1): 40-7. doi:10.1006 ... F-box only protein 7 is a protein that in humans is encoded by the FBXO7 gene. Mutations in FBXO7 have been associated with ... "Genome-wide linkage analysis of a Parkinsonian-pyramidal syndrome pedigree by 500 K SNP arrays". American Journal of Human ... This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F- ...

... "cDNA micro array identification of a gene differentially expressed in adenovirus type 5- versus type 12-transformed cells". ... Zhang Z, Henzel WJ (Oct 2004). "Signal peptide prediction based on analysis of experimentally verified cleavage sites". Protein ... Follistatin-related protein 1 is a protein that in humans is encoded by the FSTL1 gene. This gene encodes a protein with ... Ehara Y, Sakurai D, Tsuchiya N, Nakano K, Tanaka Y, Yamaguchi A, Tokunaga K (2005). "Follistatin-related protein gene (FRP) is ...

... cold-inducible RNA-binding protein) cDNA and chromosomal assignment of the gene". Gene. 204 (1-2): 115-20. doi:10.1016/S0378- ... 2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci ... Lee J, Bedford MT (2002). "PABP1 identified as an arginine methyltransferase substrate using high-density protein arrays". EMBO ... "Entrez Gene: CIRBP cold inducible RNA binding protein". Human CIRBP genome location and CIRBP gene details page in the UCSC ...

Centromere protein A, also known as CENPA, is a protein which in humans is encoded by the CENPA gene. CENPA is a histone H3 ... Figueroa J, Pendón C, Valdivia MM (May 2002). "Molecular cloning and sequence analysis of hamster CENP-A cDNA". BMC Genomics. 3 ... Shelby RD, Vafa O, Sullivan KF (February 1997). "Assembly of CENP-A into centromeric chromatin requires a cooperative array of ... "Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype". Current ...

2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs ... vena cava medial message expression by cDNA array analysis identifies a set of 68 consistently differentially expressed genes, ... Regulator of G-protein signaling 5 is a protein that in humans is encoded by the RGS5 gene. The regulator of G protein ... a novel G-protein signaling regulator gene". J Hum Genet. 43 (3): 202-5. doi:10.1007/s100380050071. PMID 9747037. "Entrez Gene ...

... for detailed analyses or optimization of protein-protein interactions Tissue microarrays Cellular microarrays (also called ... carbohydrate arrays) Phenotype microarrays Reverse phase protein lysate microarrays, microarrays of lysates or serum ... The "gene chip" industry started to grow significantly after the 1995 Science Magazine article by the Ron Davis and Pat Brown ... Types of microarrays include: DNA microarrays, such as cDNA microarrays, oligonucleotide microarrays, BAC microarrays and SNP ...

They have the largest RNA genome of any viruses, which indicates that they have a wide array of proteins that can attack host ... Reverse genetics helps to understand the function of a gene through the analysis of phenotypic effects of nucleic acid ... Yount, B.; Denison, M. R.; Weiss, S. R.; Baric, R. S. (2002-11-01). "Systematic Assembly of a Full-Length Infectious cDNA of ... These coronaviruses have all evolved to shut down immune responses but have different accessory proteins. Coronaviruses are ...

"Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome ... and expression analysis of the 12p11-p12 amplicon using EST arrays identifies two novel amplified and overexpressed genes". ... Vesicle transport protein GOT1B is a protein that in humans is encoded by the GOLT1B gene. Got1p is a protein that aides in ... It is believed that the protein is a tetra-spanning membrane protein, and is evolutionarily conserved. Homologes of the protein ...

... or testis-specific gene A2 protein (TSGA2), is a protein that in humans is encoded by the RSPH1 gene. This protein is a part of ... 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci ... doi:10.1016/j.gene.2007.02.031. PMC 1935023. PMID 17451891. Hu YH, Warnatz HJ, Vanhecke D, et al. (2006). "Cell array-based ... 2007). "Radial spoke protein 44 (human meichroacidin) is an axonemal alloantigen of sperm and cilia". Gene. 396 (1): 93-107. ...

"Comparative hybridization of an array of 21,500 ovarian cDNAs for the discovery of genes overexpressed in ovarian carcinomas". ... WAP four-disulfide core domain protein 2 - also known as Human Epididymis Protein 4 (HE4) - is a protein that in humans is ... Kirchhoff C, Osterhoff C, Habben I, Ivell R, Kirchloff C (1990). "Cloning and analysis of mRNAs expressed specifically in the ... HE4 is a tumor marker of ovarian cancer, with 80% sensitivity at a cut-off of 150 pmol/L. This gene encodes a protein that is a ...

Cysteine-rich secretory protein 3 is a cysteine-rich secretory protein that in humans is encoded by the CRISP3 gene. GRCh38: ... 2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci ... 2002). "Identification of disease-specific genes in chronic pancreatitis using DNA array technology". Ann. Surg. 234 (6): 769- ... "Entrez Gene: CRISP3 cysteine-rich secretory protein 3". Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace ...

2007). "Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening ... 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci ... The encoded protein may play a role in cell cycle progression from G2 to M phase. Mutations in the NEK8 gene associated with ... Nek8 is a member of the serine/threonine-specific protein kinase family related to NIMA (never in mitosis, gene A) of ...

A mitochondrial isozyme of the encoded protein also has been characterized. Click on genes, proteins and metabolites below to ... 2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci ... "Different transcription factor binding arrays modulate the cAMP responsivity of the phosphoenolpyruvate carboxykinase gene ... 1993). "cDNA sequence and localization of polymorphic human cytosolic phosphoenolpyruvate carboxykinase gene (PCK1) to ...

Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties including ... 2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome ... 2004). "Optimization of oligonucleotide arrays and RNA amplification protocols for analysis of transcript structure and ... Annexin A7 is a protein that in humans is encoded by the ANXA7 gene. Annexin VII is a member of the annexin family of calcium- ...