"Cytomegalovirus resistance to ganciclovir and clinical outcomes of patients with cytomegalovirus retinitis". Am J Ophthalmol. ... "Mortality associated with resistant cytomegalovirus among patients with cytomegalovirus retinitis and AIDS". Ophthalmology. 117 ... He has chaired five randomized, controlled, clinical trials on the treatment of CMV retinitis and now chairs a multicenter ... particularly CMV retinitis. Jabs has been instrumental in leading the Standardization of Uveitis (SUN) project, an effort to ...
"Oral ganciclovir for patients with cytomegalovirus retinitis treated with a ganciclovir implant. Roche Ganciclovir Study Group ... Antiviral drugs, such as ganciclovir, that target the replication of herpesviruses such as KSHV have been used to successfully ... including cytomegalovirus and HIV itself. The pathogen was ultimately identified in 1994 by Yuan Chang and Patrick S. Moore, a ...
Campbell RJ, Chow B, Victor G, Kravcik S, Hodge WG (September 2001). "Treatment of CMV retinitis with intravitral ganciclovir ... Cytomegalovirus retinitis, also known as CMV retinitis, is an inflammation of the retina of the eye that can lead to blindness ... Cytomegalovirus (CMV) Retinitis~clinical at eMedicine. Archived 7 March 2023 at archive.today "CMV , Overview , Cytomegalovirus ... The symptoms of cytomegalovirus retinitis have it usually starting in one eye (and also have the possibility of retinal ...
Since the 1990s, intravitreal antivirals have been used to treat cytomegalovirus retinitis (CMV retinitis) in immunodeficient ... Some medications that could be used include ganciclovir, foscarnet, and cidofovir. The amount and frequency of the intravitreal ... "Cytomegalovirus Adult and Adolescent Opportunistic Infection". AIDSinfo. Archived from the original on 2020-08-31. Retrieved ... Antimicrobials are intravitreally injected to treat eye infections, such as endophthalmitis and retinitis. The medication used ...
Cytomegalovirus retinitis List of systemic diseases with ocular manifestations Moorthy RS, Weinberg DV, Teich SA, Berger BB, ... Treatment for Necrotizing Herpetic Retinopathy, including ARN and PORN, includes the anti-viral medications Ganciclovir and ... Other possible diseases to consider when a patient presents with symptoms similar to PORN include: CMV retinitis, ARN, ... Minturn JT, Kumar S, Rao NA, Fowell SM, Loose IA, Jampol LM (March 1997). "Management of varicella zoster virus retinitis in ...
Ganciclovir is first phosphorylated to ganciclovir monophosphate by a viral thymidine kinase encoded by the cytomegalovirus ( ... Valganciclovir is commonly used for treatment of cytomegalovirus (CMV) retinitis (eye infection may cause blindness) in people ... Ganciclovir can also increase the concentration of didanosine. Valganciclovir is a prodrug for ganciclovir, which is a ... Valganciclovir is the L-valyl ester of ganciclovir and works when broken down into ganciclovir by the intestine and liver. ...
... which may cause fulminant liver failure cytomegalovirus retinitis (inflammation of the retina, characterised by a "pizza pie ... "A protein kinase homologue controls phosphorylation of ganciclovir in human cytomegalovirus-infected cells". Nature. 358 (6382 ... Human betaherpesvirus 5, also called human cytomegalovirus (HCMV), is species of virus in the genus Cytomegalovirus, which in ... "Outcomes in Transplant Recipients Treated with Foscarnet for Ganciclovir-Resistant or Refractory Cytomegalovirus Infection". ...
Chou S (July 2008). "Cytomegalovirus UL97 mutations in the era of ganciclovir and maribavir". Reviews in Medical Virology. 18 ( ... pharmacokinetic properties and therapeutic use in immunocompromised patients with cytomegalovirus retinitis". Drugs. 41 (1): ... or ganciclovir-resistant HSV and CMV infections. However, acyclovir- or ganciclovir-resistant mutants with alterations in viral ... Tchesnokov EP, Gilbert C, Boivin G, Götte M (February 2006). "Role of helix P of the human cytomegalovirus DNA polymerase in ...
... , sold under the brand name Cytovene among others, is an antiviral medication used to treat cytomegalovirus (CMV) ... Ganciclovir is indicated for: Sight-threatening CMV retinitis in severely immunocompromised people CMV pneumonitis in bone ... Noble S, Faulds D (July 1998). "Ganciclovir. An update of its use in the prevention of cytomegalovirus infection and disease in ... Ganciclovir has also been found to be an effective treatment for herpes simplex virus epithelial keratitis. Ganciclovir (in gel ...
Other signs and symptoms include a rash, jaundice, hepatomegaly, retinitis, and seizures. It may lead to loss of hearing or ... The options for treatment are intravenous ganciclovir and oral valganciclovir. After diagnosis, it is important to further ... Congenital cytomegalovirus (cCMV) is cytomegalovirus (CMV) infection in a newborn baby. Most have no symptoms. Some affected ... Congenital cytomegalovirus infection can be an important cause of intraventricular hemorrhage and neonatal encephalopathy. ...
Hoffman VF, Skiest DJ (February 2000). "Therapeutic developments in cytomegalovirus retinitis". Expert Opinion on ... Although this carcinogenic risk is present in other antiviral drugs, such as zidovudine and ganciclovir that have been approved ... Its mechanism of action has been found to be similar in use against human cytomegalovirus. Lobucavir's bioavailability is 30-40 ... It reached phase III clinical trials for hepatitis B and herpesvirus, phase II clinical trials for cytomegalovirus, and ...