Five Fingers GroupZinc fingerVinculum (ligament): In anatomy, a vinculum (pl. vincula) is a band of connective tissue, similar to a ligament, that connect a flexor tendon to a phalanx bone.Coles PhillipsProtein primary structure: The primary structure of a peptide or protein is the linear sequence of its amino acid structural units, and partly comprises its overall biomolecular structure. By convention, the primary structure of a protein is reported starting from the amino-terminal (N) end to the carboxyl-terminal (C) end.DNA-binding proteinPituitary-specific positive transcription factor 1: POU domain, class 1, transcription factor 1 (Pit1, growth hormone factor 1), also known as POU1F1, is a transcription factor for growth hormone.I-LIMB Hand: The i-LIMB Hand is the brand name of world's first commercially available bionic hand invented by David Gow and his team at the Bioengineering Centre of the Princess Margaret Rose Hospital in Edinburgh, and manufactured by Touch Bionics. The articulating prosthetic hand has individually powered digits and thumb and has a choice of grips.Voluntary Parenthood League: The Voluntary Parenthood League (VPL) was an organization that advocated for contraception during the birth control movement in the United States. The VPL was founded in 1919 by Mary Dennett.Vibration white finger: Vibration white finger (VWF), also known as hand-arm vibration syndrome (HAVS) or dead finger,) is a secondary form of Raynaud's syndrome, an industrial injury triggered by continuous use of vibrating hand-held machinery. Use of the term "vibration white finger" has generally been superseded in professional usage by broader concept of HAVS, although it is still used by the general public.Cable grip: thumbnail|right|[[Detachable chairlift grip. (Chair is on a sidetrack).Flexor pollicis brevis muscle: The flexor pollicis brevis is a muscle in the hand that flexes the thumb. It is one of three thenar muscles.Symmetry element: A symmetry element is a point of reference about which symmetry operations can take place. In particular, symmetry elements can be centers of inversion, axes of rotation and mirror planes.Tour SignalKLF14: Krüppel-like factor 14, also known as basic transcription element-binding protein 5 (BTEB5) is a protein that in humans is encoded by the KLF14 gene. The corresponding Klf14 mouse gene is known as Sp6.Repressor: In molecular genetics, a repressor is a DNA- or RNA-binding protein that inhibits the expression of one or more genes by binding to the operator or associated silencers. A DNA-binding repressor blocks the attachment of RNA polymerase to the promoter, thus preventing transcription of the genes into messenger RNA.DNA binding site: DNA binding sites are a type of binding site found in DNA where other molecules may bind. DNA binding sites are distinct from other binding sites in that (1) they are part of a DNA sequence (e.Proximity ligation assay: Proximity ligation assay (in situ PLA) is a technology that extends the capabilities of traditional immunoassays to include direct detection of proteins, protein interactions and modifications with high specificity and sensitivity. Protein targets can be readily detected and localized with single molecule resolution and objectively quantified in unmodified cells and tissues.FERM domain: In molecular biology, the FERM domain (F for 4.1 protein, E for ezrin, R for radixin and M for moesin) is a widespread protein module involved in localising proteins to the plasma membrane.Microneurography: Microneurography is a neurophysiological method employed by scientists to visualize and record the normal traffic of nerve impulses that are conducted in peripheral nerves of waking human subjects. The method has been successfully employed to reveal functional properties of a number of neural systems, e.Ulnar clawToe walking: Toe walking refers to a condition where a person walks on his or her toes without putting much weight on the heel or any other part of the foot. Toe walking in toddlers is common.HECT domain: In molecular biology, the HECT domain is a protein domain found in ubiquitin-protein ligases. The name HECT comes from 'Homologous to the E6-AP Carboxyl Terminus'.DNA condensation: DNA condensation refers to the process of compacting DNA molecules in vitro or in vivo. Mechanistic details of DNA packing are essential for its functioning in the process of gene regulation in living systems.Eugen von Bamberger: Eugen von Bamberger (5 September 1858 - October 1921) was an Austrian internist born in Würzburg, Germany. He was the son of pathologist Heinrich von Bamberger (1822-1888).Adult interaction with infants: When adults come into contact with infants, it is unlikely that they would be able to have a proper conversation, as the infant would not know enough about pop culture or general knowledge to create a stimulating conversation for the adult. Also, the adult may not understand baby-language and cannot relate to their situation properly.Zinc toxicityLigation-independent cloning: Ligation-independent cloning (LIC) is a form of molecular cloning that is able to be performed without the use of restriction endonucleases or DNA ligase. This allows genes that have restriction sites to be cloned without worry of chopping up the insert.CS-BLASTSilent mutation: Silent mutations are mutations in DNA that do not significantly alter the phenotype of the organism in which they occur. Silent mutations can occur in non-coding regions (outside of genes or within introns), or they may occur within exons.Aging movement control: Normal aging movement control in humans is about the changes on the muscles, motor neurons, nerves, sensory functions, gait, fatigue, visual and manual responses, in men and women as they get older but who do not have neurological, muscular (atrophy, dystrophy...) or neuromuscular disorder.GC box: In molecular biology, a GC box is a distinct pattern of nucleotides found in the promoter region of some eukaryotic genes upstream of the TATA box and approximately 110 bases upstream from the transcription initiation site. It has a consensus sequence GGGCGG which is position dependent and orientation independent.Hand deformityTwo-hybrid screeningCerebral hemisphere: The vertebrate cerebrum (brain) is formed by two cerebral hemispheres that are separated by a groove, the medial longitudinal fissure. The brain can thus be described as being divided into left and right cerebral hemispheres.Eleusine indica: Eleusine indica (Indian goosegrass, wiregrass, crowfootgrass) is a species of grass in the family Poaceae. It is a small annual grass distributed throughout the warmer areas of the world to about 50 degrees latitude.Mechanochemistry: Mechanochemistry or mechanical chemistry is the coupling of mechanical and chemical phenomena on a molecular scale and includes mechanical breakage, chemical behaviour of mechanically stressed solids (e.g.Short linear motifReaction coordinateCold shock response: Cold shock response is the physiological response of organisms to sudden cold, especially cold water.Quadriceps tendon: In human anatomy, the quadriceps tendon, also known as the patellar tendon, allows the quadriceps femoris muscles (rectus femoris, vastus lateralis, vastus medialis, and vastus intermedius)Saladin, Kenneth S. Anatomy & Physiology: The Unity of Form and Function.Ubiquitin-conjugating enzymeElectric torque wrenchRNA transfection: RNA transfection is the process of deliberately introducing RNA into a living cell. RNA can be purified from cells after lysis or synthesized from free nucleotides either chemically, or enzymatically using an RNA polymerase to transcribe a DNA template.Mature messenger RNA: Mature messenger RNA, often abbreviated as mature mRNA is a eukaryotic RNA transcript that has been spliced and processed and is ready for translation in the course of protein synthesis. Unlike the eukaryotic RNA immediately after transcription known as precursor messenger RNA, it consists exclusively of exons, with all introns removed.Early growth response proteins: Early growth response proteins are a family of zinc finger transcription factors.Protein engineering: Protein engineering is the process of developing useful or valuable proteins. It is a young discipline, with much research taking place into the understanding of protein folding and recognition for protein design principles.BESS domain: In molecular biology, the BESS domain is a protein domain which has been named after the three proteins that originally defined the domain: BEAF (Boundary element associated factor 32), Suvar(3)7 and Stonewall ). The BESS domain is 40 amino acid residues long and is predicted to be composed of three alpha helices, as such it might be related to the myb/SANT HTH domain.Stereognosis: Stereognosis (also known as haptic perception or tactile gnosis) is the ability to perceive and recognize the form of an object in the absence of visual and auditory information, by using tactile information to provide cues from texture, size, spatial properties, and temperature, etc.Yekutiel, M.Ubiquitin: Ubiquitin is a small (8.5 kDa) regulatory protein that has been found in almost all tissues (ubiquitously) of eukaryotic organisms.Myokine: A myokine is one of several hundred cytokines or other small proteins (~5–20 kDa) and proteoglycan peptides that are produced and released by muscle cells (myocytes) in response to muscular contractions.Bente Klarlund Pedersen , Thorbjörn C.Aarskog–Scott syndromeExtended physiological proprioception: Extended physiological proprioception (EPP) is a concept pioneered by D.C.Iroquois homeobox factor: Iroquois homeobox factors are a family of homeodomain transcription factors that play a role in many developmental processes.Splints: Splints is an ailment of the horse or pony, characterized by a hard, bony swelling, usually on the inside of a front leg, lying between the splint and cannon bone or on the splint bone itself. It may be "hot," meaning that it occurred recently and is still painful; or "cold," meaning that the splint has completely recovered and there is no longer any swelling or pain associated with it.Stenosing tenosynovitisMedian nerve: The median nerve is a nerve in humans and other animals in the upper limb. It is one of the five main nerves originating from the brachial plexus.Staining of the nail plate: Staining of the nail plate may occur due to nicotine, dyes (including hair dyes and nail polish), potassium permanganate, mercury compounds, hydroquinone, elemental iron, mepacrine, photographic developer, anthralin, chrysarobin, glutaraldehyde, or resorcin.James, William; Berger, Timothy; Elston, Dirk (2005).Boxcar (band): Boxcar is an Australian Sydney-based synthpop and techno band. Formed in the mid-1980s in Brisbane by main songwriter guitarist and vocalist David Smith, he was soon joined by keyboardists Brett Mitchell and Carol Rohde and somewhat later by drummer-percussionist Crispin Trist.Hand injury: The hand is a very complex organ with multiple joints, different types of ligament, tendons and nerves. With constant use, it is no wonder that hand disease injuries are common in society.Agraphesthesia: Agraphesthesia is a disorder of directional cutaneous kinesthesia or a disorientation of the skin's sensation across its space. It is a difficulty recognizing a written number or letter traced on the skin after parietal damage.PEGASUS: PEGASUS is an encryption algorithm used for satellite telemetry, command link and mission data transfers.Database of protein conformational diversity: The Database of protein conformational diversity (PCDB) is a database of diversity of protein tertiary structures within protein domains as determined by X-ray crystallography. Proteins are inherently flexible and this database collects information on this subject for use in molecular research.
Download our free solidary book to support research on VHL disease