List of diseases (E): This is a list of diseases starting with the letter "E".Keratin 5: Keratin 5, also known as KRT5, K5, or CK5, is a protein that is encoded in humans by the KRT5 gene. It dimerizes with keratin 14 and forms the intermediate filaments (IF) that make up the cytoskeleton of basal epithelial cells.Junctional epidermolysis bullosa (medicine): Junctional epidermolysis bullosa}}Epidermolysis bullosa acquisitaSuction blister: Suction blistering is a technique used in dermatology to treat chronic wounds, such as non-healing leg ulcers. When a wound is not healing properly, an autologous skin graft is the best option, to prevent rejection of the tissue.Dermal equivalent: The dermal equivalent is an in vitro model of the dermal layer of skin. It is constructed by seeding dermal fibroblasts into a collagen gel.HemidesmosomeAcroplaxomeKeratin 6A: Keratin 6A is one of the 27 different type II keratins expressed in humans. Keratin 6A was the first type II keratin sequence determined.OpsismodysplasiaLinear IgA bullous dermatosis: Linear IgA bullous dermatosis (also known as "Linear IgA dermatosis") is frequently associated with medication exposure, especially vancomycin, with men and women being equally affected.James, William; Berger, Timothy; Elston, Dirk (2005).FACIT collagen: FACIT collagen (Fibril Associated Collagens with Interrupted Triple helicesGO term: FACIT collagen) refers to a type of collagen which is also a proteoglycan.FACIT - Collagens which are proteoglycnasPedigree chart: A pedigree chart is a diagram that shows the occurrence and appearance or phenotypes of a particular gene or organism and its ancestors from one generation to the next,pedigree chart Genealogy Glossary - About.com, a part of The New York Times Company.Tonofibril: Tonofibrils, discovered by Rudolf Heidenhain, and first described in detail by Louis-Antoine Ranvier, are cytoplasmic protein structures in epithelial tissues that converge at desmosomes and hemidesmosomes. Characterized by the fine fibrils in the epithelial cells[3].Frameshift mutation: A frameshift mutation (also called a framing error or a reading frame shift) is a genetic mutation caused by indels (insertions or deletions) of a number of nucleotides in a DNA sequence that is not divisible by three. Due to the triplet nature of gene expression by codons, the insertion or deletion can change the reading frame (the grouping of the codons), resulting in a completely different translation from the original.Glomerular basement membrane: The glomerular basement membrane (GBM) of the kidney is the basal lamina layer of the glomerulus. The glomerular capillary endothelial cells, the GBM and the filtration slits between the podocytes perform the filtration function of the glomerulus, separating the blood in the capillaries from the filtrate that forms in Bowman's capsule.Enteric duplication cyst: Enteric duplication cysts, sometimes simply called duplication cysts, are rare congenital malformations of the gastrointestinal tract. They most frequently occur in the small intestine, particularly the ileum, but can occur anywhere along the gastrointestinal tract.Nonsense mutation: In genetics, a nonsense mutation is a point mutation in a sequence of DNA that results in a premature stop codon, or a nonsense codon in the transcribed mRNA, and in a truncated, incomplete, and usually nonfunctional protein product. It differs from a missense mutation, which is a point mutation where a single nucleotide is changed to cause substitution of a different amino acid.Silent mutation: Silent mutations are mutations in DNA that do not significantly alter the phenotype of the organism in which they occur. Silent mutations can occur in non-coding regions (outside of genes or within introns), or they may occur within exons.Keratolytic winter erythemaCollagenBiotextile: Biotextiles are structures composed of textile fibers designed for use in specific biological environments where their performance depends on biocompatibility and biostability with cells and biological fluids. Biotextiles include implantible devices such as surgical sutures, hernia repair fabrics, arterial grafts, artificial skin and parts of artificial hearts.Umbilical cord ulceration and intestinal atresia: Umbilical cord ulceration and intestinal atresia is a rare congenital disease that leads to intestinal atresia, umbilical cord ulceration and severe intrauterine haemorrhage. Only 15 cases have so far been report though newer studies are beginning to conclude that this disease has a higher incidence rate than has been previously reported.Gag/pol translational readthrough site: Gag/pol translational readthrough site (or Retroviral readthrough element) is a cis-regulatory element found in retroviruses. The readthrough site facilitates the mechanism of translation readthrough of the stop codon at the gag-pol junction producing the gag and pol fusion protein in certain retroviruses.List of target antigens in pemphigoid: Circulating auto-antibodies in the human body can target normal parts of the skin leading to disease. This is a list of antigens in the skin that may become targets of circulating auto-antibodies leading to the various types of pemphigoid.Intermediate filament: Intermediate filaments (IFs) are cytoskeletal components found in the cells of many animal species.Karabinos, Anton, Dieter Riemer, Andreas Erber, and Klaus Weber.Reticular fiber: Reticular fibers, reticular fibres or reticulin is a type of fiber in connective tissue composed of type III collagen secreted by reticular cells. Reticular fibers crosslink to form a fine meshwork (reticulin).Phenotype microarray: The phenotype microarray approach is a technology for high-throughput phenotyping of cells.Prurigo pigmentosa: Prurigo pigmentosa is a rare skin condition of unknown cause, characterized by the sudden onset of erythematous papules that leave a reticulated hyperpigmentation when they heal.James, William; Berger, Timothy; Elston, Dirk (2005).TurbinectomyLaminin: Laminins are high-molecular weight (~400kDa) proteins of the extracellular matrix. They are a major component of the basal lamina (one of the layers of the basement membrane), a protein network foundation for most cells and organs.Iridogoniodysgenesis, dominant type: Iridogoniodysgenesis, dominant type (type 1, IRID1) refers to a spectrum of diseases characterized by malformations of the irido-corneal angle of the anterior chamber of the eye. Iridogoniodysgenesis is the result of abnormal migration or terminal induction of neural crest cells.Point mutationConfined placental mosaicism: Confined placental mosaicism (CPM) represents a discrepancy between the chromosomal makeup of the cells in the placenta and the cells in the baby. CPM was first described by Kalousek and Dill in 1983.Gross examinationAlternative splicing: Alternative splicing is a regulated process during gene expression that results in a single gene coding for multiple proteins. In this process, particular exons of a gene may be included within or excluded from the final, processed messenger RNA (mRNA) produced from that gene.Calamine: Calamine is either a mixture of zinc oxide (ZnO) with about 0.5% ferric oxide (Fe2O3) or a zinc carbonate compound.Keratinocyte: A keratinocyte is the predominant cell type in the epidermis, the outermost layer of the skin, constituting 90% of the cells found there.Autoantibody: An autoantibody is an antibody (a type of protein) produced by the immune system that is directed against one or more of the individual's own proteins. Many autoimmune diseases, (notably lupus erythematosus), are caused by such autoantibodies.Coles PhillipsDown syndrome cell adhesion molecule like 1: Down syndrome cell adhesion molecule like 1 is a protein in humans that is encoded by the DSCAML1 gene.Relapsing linear acantholytic dermatosis: Relapsing linear acantholytic dermatosis is a cutaneous condition characterized by relapsing linear erosions and crusting, histologically identical to Hailey–Hailey disease. It is not to be confused with transient acantholytic dermatosis.RDCRN Contact Registry: The Rare Diseases Clinical Research Network (RDCRN) Contact Registry is an international patient contact registry sponsored by the National Institutes of Health. This registry collects basic data (i.Symmetry element: A symmetry element is a point of reference about which symmetry operations can take place. In particular, symmetry elements can be centers of inversion, axes of rotation and mirror planes.Low-voltage electron microscope: Low-voltage electron microscope (LVEM) is an electron microscope which operates at accelerating voltages of a few kiloelectronvolts or less. While the low voltage electron microscopy technique will never replace conventional high voltage electron microscopes, it is quickly becoming appreciated for many different disciplines.Missense mutation: In genetics, a missense mutation (a type of nonsynonymous substitution) is a point mutation in which a single nucleotide change results in a codon that codes for a different amino acid. Another type of nonsynonymous substitution is a nonsense mutation in which a codon is changed to a premature stop codon that results in truncation of the resulting protein.Dermal fibroblast: Dermal fibroblasts are cells within the dermis layer of skin which are responsible for generating connective tissue and allowing the skin to recover from injury. Using organelles (particularly the rough endoplasmic reticulum), dermal fibroblasts generate and maintain the connective tissue which unites separate cell layers.Uremic pruritus: Uremic pruritus (also known as uraemic pruritus or renal pruritus) is caused by chronic kidney failure and is the most common internal systemic cause of itching.James, William; Berger, Timothy; Elston, Dirk (2005).Prenatal diagnosis: Prenatal diagnosis or prenatal screening (note that prenatal diagnosis and prenatal screening refer to two different types of tests) is testing for diseases or conditions in a fetus or embryo before it is born. The aim is to detect birth defects such as neural tube defects, Down syndrome, chromosome abnormalities, genetic disorders and other conditions, such as spina bifida, cleft palate, Tay Sachs disease, sickle cell anemia, thalassemia, cystic fibrosis, Muscular dystrophy, and fragile X syndrome.Epidermolytic hyperkeratosis