3 proteins and cruciform DNA serve a role in origin firing which in turn will activate DNA helicase to begin the process of DNA ... Cruciform DNA is a form of non-B DNA, or an alternative DNA structure. The formation of cruciform DNA requires the presence of ... A multitude of cruciform-binding proteins have been found to interact with cruciform DNA structures that act as recognition ... Specifically, the WRN protein unwinds Holliday junctions, which are a subset of cruciform DNA structures, to prevent DNA ...

The human DEK gene encodes the DEK protein. This gene encodes a protein with one SAP domain. The protein binds to cruciform DNA ... Waldmann T, Eckerich C, Baack M, Gruss C (2002). "The ubiquitous chromatin protein DEK alters the structure of DNA by ... "The protein encoded by the proto-oncogene DEK changes the topology of chromatin and reduces the efficiency of DNA replication ... PDBe-KB provides an overview of all the structure information available in the PDB for Human Protein DEK v t e (Articles with ...

Like RHR initiator proteins, many RCR initiator proteins contain helicase activity, which allows them to melt the DNA prior to ... The residual cruciform, called δJ, is partially single-stranded at the upper part of the B arm and contains the intact upper ... NS1 is a site-specific DNA binding protein that acts as the replication initiator protein via nickase activity. It also ... Parvoviruses are a family of DNA viruses that have single-stranded DNA (ssDNA) genomes enclosed in rugged, icosahedral protein ...

... which are then cleaved in a variety of patterns by proteins. An animation of this process can be seen here. Double-strand DNA ... cruciform structures involving Holliday junctions can arise to relieve helical strain in symmetrical sequences in DNA ... As this bubble nears the broken DNA, the longer 5' antisense strand again invades the sense strand of this portion of DNA, ... A number of natural branched DNA structures were known at the time, including the DNA replication fork and the mobile Holliday ...

Cruciform DNA Cruciform DNA is a form of non-B DNA that requires at least a 6 nucleotide sequence of inverted repeats to form a ... Important in DNA binding proteins. Helix-turn-helix Two α helices joined by a short strand of amino acids and found in many ... stabilized by negative DNA supercoiling. Two classes of cruciform DNA have been described; folded and unfolded. G-quadruplex G- ... D-loop A displacement loop or D-loop is a DNA structure where the two strands of a double-stranded DNA molecule are separated ...

The NS gene encodes the non-structural (NS) protein NS1, which is the replication initiator protein, and the VP gene encodes ... end of the DNA attached to the capsid. Parvoviruses lack the ability to induce cells into their DNA replication stage, called S ... A replication origin site on the lower strand of the right arm of the cruciform is nicked by NS1, leading to the lower arm of ... Translation of mRNA containing VP proteins leads to the accumulation of capsid proteins in the nucleus that assemble into these ...

"DNA-binding parameters of the HU protein of Escherichia coli to cruciform DNA". Journal of Molecular Biology. 242 (2): 116-29. ... Examples of distorted DNA substrates include cruciform DNA, bulged DNA, dsDNA containing a single-stranded break such as nicks ... targets regions of DNA containing cruciform structures and forms an RNA-DNA complex that is critical for establishing DNA-DNA ... How does MatP condense DNA and promote DNA-DNA contacts? The experimental results are conflicting. MatP can form a DNA loop ...

... is a protein that in humans is encoded by the LAMC1 gene. Laminins, a family of extracellular matrix ... Santos CL, Sabbaga J, Brentani R (1992). "Differences in human laminin B2 sequences". DNA Seq. 1 (4): 275-7. doi:10.3109/ ... and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of ... Hunter DD, Shah V, Merlie JP, Sanes JR (1989). "A laminin-like adhesive protein concentrated in the synaptic cleft of the ...

... and cruciform-cutting endonuclease, is an enzyme involved in DNA repair and homologous recombination. Specifically, it performs ... E. coli RuvC, a Crossover junction endodeoxyribonuclease, is a small protein of about 20 kD, and its active form is a dimer ... Crossover junction endodeoxyribonucleases also play key roles in DNA repair. During cell growth and meiosis, DNA double-strand ... Iwasaki H, Takahagi M, Shiba T, Nakata A, Shinagawa H (December 1991). "Escherichia coli RuvC protein is an endonuclease that ...

... or cruciform-like DNA structures. These special structures can hinder or confuse DNA replication and other genomic activities. ... interplay between DNA hairpins and fork stabilizing proteins". Proceedings of the National Academy of Sciences of the United ... It covers the A-DNA and Z-DNA conformations otherwise known as "non-B DNAs" because they are not the more common B-DNA form of ... The illustration shows an inverted repeat undergoing cruciform extrusion. DNA in the region of the inverted repeat unwinds and ...

... also known as LAMC3 is a protein that in humans is encoded by the LAMC3 gene. Laminins, a family of ... DNA Res. 12 (2): 117-26. doi:10.1093/dnares/12.2.117. PMID 16303743. Burgeson RE, Chiquet M, Deutzmann R, et al. (1994). "A new ... and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of ... Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. ...

The relatively large stomach is bright red and has a cruciform shape in cross section. Young specimens 1 mm in diameter have ... Analysis of nucleotide sequence homologs and protein homologs identified Nemopsis bachei as the species' closest relative. None ... DNA replication and repair, and stem cell renewal. Keeping T. dohrnii in captivity is quite difficult. Currently, only one ... Genomic analyses such as sequence analysis on mRNA or mitochondria DNA have been employed to investigate its lifecycle. mRNA ...

Homeobox protein EMX1 is a protein that in humans is encoded by the EMX1 gene. The transcribed EMX1 gene is a member of the EMX ... Solaro P, Greger B, Kemper B (1995). "Detection and partial purification of a cruciform-resolving activity (X-solvase) from ... 2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4". Nature. 434 (7034): 724-31. Bibcode: ...

Interplay between DNA hairpins and fork stabilizing proteins". Proceedings of the National Academy of Sciences. 105 (29): 9936- ... Dayn, Andrey; Malkhosyan, Sergei; Mirkin, Sergei M. (1992). "Transcriptionally driven cruciform formation in vivo". Nucleic ... H-DNA); detection of dynamic non-B DNA structures, including DNA cruciforms and triplexes in vivo; establishing that structure- ... prone DNA repeats stall DNA replication driving their expansions that are responsible for numerous hereditary diseases in ...

One of the satellite tombs, Tomb 27, has a cruciform passage tomb plan, a feature seen in the chambers of later passage tombs ... The analysis of ancient DNA derived from human bone shows a web of connections between occupants of monuments of the Irish ... This (combined with stable isotope results indicating a more protein rich diet than that of the general Neolithic population) ... 2020). Ancient DNA in Ireland: Isolation, immigration and elite incest. British Archaeology Schulting, R., McClatchie, M., ...

This facilitates the accessibility of DNA-repairing proteins, such as DNA polymerase K, so that they can fulfil their function ... The tRNA's cruciform structure is incredibly important to its overall function and such a complicated structure is maintained ... Members of the YTH domain protein family act as "readers" of m6A. The study of these proteins has been key in understanding the ... Uniquely, DNMT-2 is the only DNMT that has been confirmed to methylate both DNA and RNA, although its overall DNA methylation ...

They had also learned techniques for drying fish, which were an important source of protein; they began trading the dried fish ... The genomes of Africans commonly found to undergo adaptation are regulatory DNA, and many cases of adaptation found among ... cruciform, lizards, double-bladed throwing knives, small axes, oval-bladed throwing knives with handles and spurs. There are ... Sub-Saharan African mitochondrial DNA was introduced into Europe and Asia. Mitochondrial haplogroup L1c is strongly associated ...

"Distinct evolutionary histories of the DNA-A and DNA-B components of bipartite begomoviruses". BMC Evolutionary Biology. 10 (1 ... Virusoids are essentially viroids that have been encapsulated by a helper virus coat protein. They are thus similar to viroids ... Foreign nucleotides introduced into the molecule will only be tolerated if they preserve the overall cruciform structure of the ... Abouhaidar et al., 2014 demonstrated the only example of protein translation and messenger RNA activity in the Rice yellow ...

Through analysis of DNA and protein traces, the researchers were able to identify the contents of Ötzi's last meal, composed of ... as well as a cruciform mark behind the right knee and on the right ankle, and parallel lines around the left wrist. The ... DNA analysis also showed him at high risk of atherosclerosis and lactose intolerance, with the presence of the DNA sequence of ... DNA analyses taken in 2003 are claimed to have revealed traces of blood from at least four other people on his gear: one from ...

... using mitochondrial DNA and Y-chromosome DNA, respectively. Mitochondrial DNA ("mtDNA") and Y-chromosome DNA differ from the ... Another isotopic method has been employed to investigate whether protein sources in human diets in the early Anglo-Saxon varied ... "Celtic whispers: revisiting the problems of the relation between Brittonic and Old English". Toby F. Martin, The Cruciform ... Many of the earliest attempts to examine the ancestry of British people using molecular evidence looked at Y chromosome DNA. ...

Isolated human DNA [Original draft with this number was related to cranes] ISO 4308 Cranes and lifting appliances - Selection ... internal offset cruciform ribbed or unribbed drive, threaded to head, MJ threads, metallic material, coated or uncoated, ... Determination of reduction activity of specific proteins derived from pollen, mite and other sources on textile products [Under ... Information of Clinical Massive Parallel DNA Sequencing [Under development; original draft with this number unknown] ISO 4425 ...