Cocaine intoxicationDopamine reuptake inhibitor: A dopamine reuptake inhibitor (DRI) is a type of drug which acts as a reuptake inhibitor of the monoamine neurotransmitter dopamine by blocking the action of the dopamine transporter (DAT). Reuptake inhibition is achieved when extracellular dopamine not absorbed by the postsynaptic neuron is blocked from re-entering the presynaptic neuron.Crack cocaine: Crack cocaine is the freebase form of cocaine that can be smoked. It may also be termed rock, work, hard, iron, cavvy, base, but is most commonly known as just crack; the Manual of Adolescent Substance Abuse Treatment calls it the most addictive form of cocaine.Self-administration: Self-administration is, in its medical sense, the process of a subject administering a pharmacological substance to him-, her-, or itself. A clinical example of this is the subcutaneous "self-injection" of insulin by a diabetic patient.Synaptic gating: Synaptic gating is the ability of neural circuits to gate inputs by either suppressing or facilitating specific synaptic activity. Selective inhibition of certain synapses has been studied thoroughly (see Gate theory of pain), and recent studies have supported the existence of permissively gated synaptic transmission.Information hypothesis of conditioned reinforcementExercise addiction: An exercise addiction can have harmful consequences although it is not listed as a disorder in the latest revision of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV). This type of addiction can be classified under a behavioral addiction in which a person’s behavior becomes obsessive, compulsive, and/or causes dysfunction in a person's life.Olson's Extinction: Olson's Extinction was a mass extinction that occurred in the Early Guadalupian of the Permian period and which predated the Permian–Triassic extinction event.Concentration effect: In the study of inhaled anesthetics, the concentration effect is the increase in the rate that the Fa(alveolar concentration)/Fi(inspired concentration) ratio rises as the alveolar concentration of that gas is increased. In simple terms, the higher the concentration of gas administered, the faster the alveolar concentration of that gas approaches the inspired concentration.Dopamine receptorUniform State Narcotic Drug Act: The National Conference of Commissioners on Uniform State Laws developed the Uniform State Narcotic Drug Act in 1934 due to the lack of restrictions in the Harrison Act of 1914. The act was a revenue-producing act and, while it provided penalties for violations, it did not give authority to the states to exercise police power regarding either seizure of drugs used in illicit trade or punishment of those responsible.Jaehoon Ahn: Jaehoon Ahn (May 13, 1941 – June 1, 2011) was a North Korean-born American journalist and researcher. Ahn worked as a researcher for the Washington Post for more than twenty-five years, until 1996.Benzodiazepine withdrawal syndromeReward system: The reward system is a group of neural structures that are critically involved in mediating the effects of reinforcement. A reward is an appetitive stimulus given to a human or some other animal to alter its behavior.Drug test: A drug test is a technical analysis of a biological specimen, for example urine, hair, blood, breath, sweat, or oral fluid/saliva—to determine the presence or absence of specified parent drugs or their metabolites. Major applications of drug testing include detection of the presence of performance enhancing steroids in sport, employers screening for drugs prohibited by law (such as cannabis, cocaine and heroin) and police officers testing for the presence and concentration of alcohol (ethanol) in the blood commonly referred to as BAC (blood alcohol content).CymserineList of drug interactions: The following is a list of interactions with various prescription and over-the counter drugs:Substance-related disorderTalipexoleComfort Food (novel): Comfort Food: A Novel by Noah Ashenhurst contains a cast of characters: a romantic academic, a self-assured young writer, an enigmatic musician, a slacker, a wealthy mountaineer, and a former heroin addict—characters whose lives intersect in the unique, award-winning debut novel.Ventral tegmental area: The ventral tegmental area (VTA), (tegmentum is Latin for covering), also known as the ventral tegmental area of Tsai, or simply ventral tegmentum, is a group of neurons located close to the midline on the floor of the midbrain (mesencephalon). The VTA is the origin of the dopaminergic cell bodies of the mesocorticolimbic dopamine system and is widely implicated in the drug and natural reward circuitry of the brain.Frontostriatal circuit: Frontostriatal circuits are neural pathways that connect frontal lobe regions with the basal ganglia (striatum) that mediate motor, cognitive, and behavioural functions within the brain. They receive inputs from dopaminergic, serotonergic, noradrenergic, and cholinergic cell groups that modulate information processing.Conditioned place preference: Conditioned place preference (CPP) is a form of Pavlovian conditioning used to measure the motivational effects of objects or experiences. This paradigm can also be used to measure conditioned place aversion with an identical procedure involving aversive stimuli instead.Grotto of the RedemptionCue stick: A cue stick (or simply cue, more specifically pool cue, snooker cue, or billiards cue), is an item of sporting equipment essential to the games of pool, snooker and carom billiards. It is used to strike a ball, usually the .NafadotrideDrug interaction: A drug interaction is a situation in which a substance (usually another drug) affects the activity of a drug when both are administered together. This action can be synergistic (when the drug's effect is increased) or antagonistic (when the drug's effect is decreased) or a new effect can be produced that neither produces on its own.Temporal analysis of products: Temporal Analysis of Products (TAP), (TAP-2), (TAP-3) is an experimental technique for studyingMethadone clinic: A methadone clinic is a clinic which has been established for the dispensing of methadone (Dolophine), a schedule II opioid analgesic, to those who abuse heroin and other opioids. The focus of these clinics is the elimination or reduction of opioid usage by putting the patient on methadone.Prenatal methamphetamine exposure: Prenatal methamphetamine exposure (PME) is the exposure of a prenatal fetus to methamphetamine when a woman uses the drug during her pregnancy. Methamphetamine (MA) has shown increasing popularity in the past two decades among women of childbearing age.DextroamphetamineSubstituted amphetamine: Substituted amphetamines are a class of compounds based upon the amphetamine structure; it includes all derivative compounds which are formed by replacing, or substituting, one or more hydrogen atoms in the amphetamine core structure with substituents. The compounds in this class span a variety of pharmacological subclasses, including stimulants, entactogens, hallucinogens, among others.Anatoxin-aBenazeprilChlorophyllase: Chlorophyllase (klawr-uh-fil-eys)chlorophyllase - Definitions from Dictionary.com is the key enzyme in chlorophyll metabolism.Gas chromatography–mass spectrometry: right|300 px|Example of a GC-MS instrument|thumbBenzyl benzoate/disulfiram: Benzyl benzoate/disulfiram (trade name Tenutex) is a combination drug used in the treatment of scabies. It consists of the antiparasitic insecticides benzyl benzoate and disulfiram.
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