Inheritance of extrachromosomal DNA differs from the inheritance of nuclear DNA found in chromosomes. Unlike chromosomes, ecDNA ... This uniparental inheritance is an example of non-Mendelian inheritance. Plants also show uniparental mtDNA inheritance. Most ... Extrachromosomal DNA (abbreviated ecDNA) is any DNA that is found off the chromosomes, either inside or outside the nucleus of ... Extrachromosomal DNA (ecDNA) found in cancer have historically been referred to as Double minute chromosomes (DMs), which ...
... extrachromosomal inheritance MeSH G13.420.275.500 - genes, mitochondrial MeSH G13.420.320 - genes, dominant MeSH G13.420.325 - ... chromosome fragility MeSH G13.920.590.175.175 - chromosome breakage MeSH G13.920.590.175.177 - chromosome deletion MeSH G13.920 ... ring chromosomes MeSH G13.920.590.175.815 - sex chromosome aberrations MeSH G13.920.590.175.815.970 - xyy karyotype MeSH ... 420 - inversion, chromosome MeSH G13.920.590.175.430 - isochromosomes MeSH G13.920.590.175.570 - micronuclei, chromosome- ...
"Extrachromosomal element capture and the evolution of multiple replication origins in archaeal chromosomes". Proceedings of the ... Although DNA replication is essential for genetic inheritance, defined, site-specific replication origins are technically not a ... Eukaryotic chromosomes are also much larger than their bacterial counterparts, raising the need for initiating DNA synthesis ... Most bacterial chromosomes are circular and contain a single origin of chromosomal replication (oriC). Bacterial oriC regions ...
May 2018). "Discordant inheritance of chromosomal and extrachromosomal DNA elements contributes to dynamic disease evolution in ... or nested positions on the same chromosome or across different chromosomes. eccDNAs originate mostly from single, continuous ... Extrachromosomal DNA Extrachromosomal rDNA circle Double minute microDNA Selfish genetic elements Paulsen T, Kumar P, Koseoglu ... identified that double minutes only comprise roughly 30% of extrachromosomal DNA. Thus, the term extrachromosomal circular DNA ...
... by naming the chromosome theory of inheritance the Boveri-Sutton chromosome theory (the names are sometimes reversed). Ernst ... Certain bacteria also contain plasmids or other extrachromosomal DNA. These are circular structures in the cytoplasm that ... Chromosomes can also be fused artificially. For example, the 16 chromosomes of yeast have been fused into one giant chromosome ... Chromosomes in humans can be divided into two types: autosomes (body chromosome(s)) and allosome (sex chromosome(s)). Certain ...
The "end replication problem" is exclusive to linear chromosomes as circular chromosomes do not have ends lying without reach ... Blackburn EH, Gall JG (March 1978). "A tandemly repeated sequence at the termini of the extrachromosomal ribosomal RNA genes in ... They have provided evidence for the inheritance of telomere length; however, heritability estimates vary greatly within and ... and hypothesized the existence of a special structure at the chromosome tip that would maintain chromosome stability. During ...
The gene then needs to be mapped by comparing the inheritance of the phenotype with known genetic markers. Genes that are close ... If the position of the gene can be determined using molecular markers then chromosome walking is one way to isolate the correct ... Once the gene is constructed it must be stably integrated into the genome of the target organism or exist as extrachromosomal ... Up-taken DNA can either integrate with the bacterials genome or, more commonly, exist as extrachromosomal DNA. In plants the ...
... of a linear chromosome or chromosome fragment) Having a centromere positioned at the terminal end of the chromosome (near or ... unequal crossing over uniparental inheritance unique DNA A class of DNA sequences determined by C0t analysis to be present only ... generally inclusive of all chromosomal and extrachromosomal (e.g. mitochondrial) DNA. wild type (WT) The phenotype of the ... of a linear chromosome or chromosome fragment) Having a centromere positioned in the middle of the chromosome, resulting in ...
extracellular matrix (ECM) extrachromosomal DNA Any DNA that is not found in chromosomes or in the nucleus of a cell and hence ... inheritance See heredity. initiation codon See start codon. inosine insertion A type of mutation in which one or more bases are ... In humans, the X chromosome and the Y chromosome are sex chromosomes. alpha helix (α-helix) A common structural motif in the ... of a linear chromosome or chromosome fragment) Having a centromere positioned very close to one end of the chromosome, as ...
LINE1s can only retrotranspose in some cases to form different chromosome structures contributing to differences in genetics ... transgenerational epigenetic inheritance to convey a memory of past transposon activity, and RNA-induced epigenetic silencing. ... discontinuous reverse transcriptase-mediated extrachromosomal recombination. These retrotransposons are regulated by a family ...
It is the partial repeat sequence that prevents the CRISPR-Cas system from targeting the chromosome as base pairing beyond the ... For this reason, Koonin described CRISPR-Cas as a Lamarckian inheritance mechanism. However, this was disputed by a critic who ... In 2005, three independent research groups showed that some CRISPR spacers are derived from phage DNA and extrachromosomal DNA ... A subtype of chromosomal islands called phage-inducible chromosomal island (PICI) is excised from a bacterial chromosome upon ...
When the chromosome is replicated, this gives rise to one daughter chromosome that is heavily methylated downstream of the ... Epigenetic inheritance of depression-related phenotypes has also been reported in a preclinical study. Inheritance of paternal ... Liebman SW, Sherman F (September 1979). "Extrachromosomal psi+ determinant suppresses nonsense mutations in yeast". Journal of ... Two important ways in which epigenetic inheritance can differ from traditional genetic inheritance, with important consequences ...
All 16 chromosomes can be fused into one single chromosome by successive end-to-end chromosome fusions and centromere deletions ... Over-expression of the genes sir2 and fob1 has been shown to increase RLS by preventing the accumulation of extrachromosomal ... Life Cycle and Inheritance. Cold Spring Harbor, N.Y.: Cold Spring Harbor Laboratory. pp. 371-414. ISBN 978-0-87969-139-4. Game ... In the latter case the 16 chromosomes of yeast are represented by the letters A to P, then the gene is further classified by a ...