Adjuvant chemotherapy appears to be ineffective in people with completely resected tumors. The role of combined ... If the tumor can be removed surgically, people may receive adjuvant chemotherapy or radiation therapy after the operation to ... October 2002). "Is postoperative adjuvant chemotherapy useful for gallbladder carcinoma? A phase III multicenter prospective ... then adjuvant therapy with radiation and possibly chemotherapy is generally recommended based on the available data. The ...
November 2008). "Retrospective review of adjuvant chemotherapy for esthesioneuroblastoma". Journal of Neuro-Oncology. 90 (2): ... then for radiotherapy and chemotherapy (51%), just surgery (48%), surgery, radiotherapy and chemotherapy (47%) and finally just ... Chemotherapy is used in a multimodality treatment plan generally for more advanced, unresectable or reoccurring tumors. ... More progressed, higher grade tumors would result in chemotherapy or radiotherapy as the only treatment. It is no surprise that ...
January 2016). "Is adjuvant chemotherapy indicated in ovarian immature teratomas? A combined data analysis from the Malignant ... Tay SK, Tan LK (January 2000). "Experience of a 2-day BEP regimen in postsurgical adjuvant chemotherapy of ovarian germ cell ... In adult women postoperative adjuvant chemotherapy is standard except for stage I /grade 1 disease. In pediatric patients, ... However, these results antedate the use of multi-agent chemotherapy. With the advent of multiagent chemotherapy after surgical ...
Falcetta FS, Medeiros LR, Edelweiss MI, Pohlmann PR, Stein AT, Rosa DD (November 2016). "Adjuvant platinum-based chemotherapy ... "Adjuvant chemotherapy after concurrent chemoradiation for locally advanced cervical cancer". The Cochrane Database of ... which then usually requires adjuvant radiation therapy), or cisplatin chemotherapy followed by hysterectomy. When cisplatin is ... In addition, chemotherapy can be used to treat cervical cancer, and has been found to be more effective than radiation alone. ...
Albain, K. S.; Paik, S.; Van't Veer, L. (2009). "Prediction of adjuvant chemotherapy benefit in endocrine responsive, early ... October 2005). "Trastuzumab plus adjuvant chemotherapy for operable HER2+ breast cancer". The New England Journal of Medicine. ... The choice of established chemotherapy medications, if chemotherapy is needed, may also be affected by DNA assays that predict ... Adjuvant! is based on US cohorts and presents colored bar charts that display information that may assist in decisions ...
Standard treatment is surgery with adjuvant chemotherapy and radiotherapy. Surgery is primarily used for early stage disease ... adjuvant, or metastatic disease should be offered PARP inhibitor rather than chemotherapy. Sacituzumab govitecan (Trodelvy ) is ... Neoadjuvant chemotherapy (before surgery) is very frequently used for triple-negative breast cancers as they are more ... Chemotherapy used to treat early stage cancers are: anthracyclines alkalating agents such as cisplatin and carboplatin. These ...
"Adjuvant platinum-based chemotherapy for early stage cervical cancer". The Cochrane Database of Systematic Reviews. 11 (11): ... These drugs are used to treat almost half of people receiving chemotherapy for cancer. In this form of chemotherapy, commonly ... the addition of cisplatin to adjuvant chemotherapy led to a marked increase in disease-free survival rates for patients with ... Oun R, Moussa YE, Wheate NJ (2018). "The side effects of platinum-based chemotherapy drugs: a review for chemists". Dalton ...
October 2005). "Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer". The New England Journal of Medicine. ... August 2010). "Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced ... Drugs used for chemotherapy are too toxic to give to healthy individuals, which makes it difficult to perform genetic studies ... Then, in 2005, it was shown that trastuzumab is effective as an adjuvant treatment in women with early-stage breast cancer. ...
February 2013). "Adjuvant radiotherapy and/or chemotherapy after surgery for uterine carcinosarcoma". The Cochrane Database of ... who were treated with combination chemotherapy including Ifosfamide, were at lower risk of disease progression and death than ...
February 1976). "Combination chemotherapy as an adjuvant treatment in operable breast cancer". N. Engl. J. Med. 294 (8): 405-10 ... ISBN 978-1-4391-0795-9. Time line for cancer chemotherapy A time line of milestones in cancer chemotherapy from the National ... proved that adjuvant chemotherapy after complete surgical resection of breast tumours significantly extended survival - ... The era of cancer chemotherapy began in the 1940s with the first use of nitrogen mustards and folic acid antagonist drugs. The ...
Adjuvant chemotherapy and/or radiotherapy in malignant SFT remains controversial. SFT was first mentioned in the scientific ...
"Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer". The New England Journal of Medicine. 353 (16 ... adjuvant treatment of breast cancer, the treatments of metastatic HER2+ breast cancer, cardiotoxicity, as well as health care ... the National Surgical Adjuvant Breast and Bowel Project (NSABP), and the National Accreditation Program for Breast Centers. ...
Adjuvant chemotherapy in older women with early-stage breast cancer. New England Journal of Medicine. 2009;360:2055-2065. Sikov ... Adjuvant Paclitaxel and Trastuzumab for Node-Negative, HER2-Positive Breast Cancer. New England Journal of Medicine. 2015;372: ... Estrogen-Receptor Status and Outcomes of Modern Chemotherapy for Patients with Node-Positive Breast Cancer. JAMA. 2006;295:1658 ... assessing the use of aspirin as adjuvant therapy for node-positive breast cancer patients. Winer has authored over 400 ...
October 2005). "Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer". The New England Journal of ... October 2005). "Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer". The New England Journal of Medicine. ... February 2006). "Adjuvant docetaxel or vinorelbine with or without trastuzumab for breast cancer". The New England Journal of ... It may be used by itself or together with other chemotherapy medication. Trastuzumab is given by slow injection into a vein and ...
Medications used after and in addition to surgery are called adjuvant therapy. Chemotherapy or other types of therapy prior to ... October 2005). "Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer". The New England Journal of ... Also, when chemotherapy is being given after birth, many of the drugs pass through breast milk to the baby, which could harm ... Chemotherapy is predominantly used for cases of breast cancer in stages 2-4, and is particularly beneficial in estrogen ...
"Combination Chemotherapy as an Adjuvant Treatment in Operable Breast Cancer". New England Journal of Medicine. 294 (8): 405-410 ... technique for breast conserving surgery and initiated the first trials investigating the impact of adjuvant chemotherapy in ... Rizzoli, Milan "History". Pinedo, Herbert (1979) Cancer Chemotherapy. Elsevier Science Publishing Company BV. ISBN ... and author of early editions of Cancer Chemotherapy; Franco Cavalli, a Swiss haematologist and founding member of the European ...
adjuvant chemotherapy. With knowledge from the TCGA, a new classification of urothelial cancer by molecular markers has become ... A meta-analysis showed that overall there is an OS benefit of immediate adjuvant chemotherapy, especially with cisplatin-based ... She has published on behalf of the EORTC and several large cooperative groups the largest randomized adjuvant chemotherapy ... This trial demonstrated the value of adjuvant chemotherapy after cystectomy. ...
There is evidence to suggest that doxorubicin chemotherapy as an adjuvant can reduce recurrence at the original site or ... "Adjuvant chemotherapy for localised resectable soft tissue sarcoma in adults". Cochrane Database of Systematic Reviews. 2000 (4 ... The use of chemotherapy to prevent the spread of soft-tissue sarcomas has not been proven to be effective. If the cancer has ... Chemotherapy may be used with radiation therapy either before or after surgery to try to shrink the tumor or kill any remaining ...
Sakuramoto (1 November 2007). "Adjuvant chemotherapy for gastric cancer with S-1, an oral fluoropyrimidine". NEJM. 357 (18): ... in Japan for most cancers while overall survival tends to be longer in the US due to the more aggressive use of chemotherapy in ... cancer is better in Japan than the US in both patients treated with surgery alone and surgery followed by chemotherapy. Japan ...
September 2006). "DNA repair by ERCC1 in non-small-cell lung cancer and cisplatin-based adjuvant chemotherapy". The New England ... ERCC1-positive NSCLC tumors do not benefit from adjuvant platinum chemotherapy. However, ERCC1-negative NSCLC tumors, ... derive substantial benefit from adjuvant cisplatin-based chemotherapy. High ERCC1 is thus a negative predictive marker, ... Olaussen KA, Mountzios G, Soria JC (July 2007). "ERCC1 as a risk stratifier in platinum-based chemotherapy for nonsmall-cell ...
They are treated with surgery and adjuvant platinum chemotherapy or radiation. Yolk sac tumors, formerly called endodermal ... Most germ-cell cancers have a better prognosis than other subtypes and are more sensitive to chemotherapy. They are more likely ... Treatment usually includes some combination of surgery, radiation therapy, and chemotherapy. Outcomes depend on the extent of ... Ovarian clear-cell carcinoma does not typically respond well to chemotherapy due to intrinsic chemoresistance, therefore ...
Patients with ICCB may also receive adjuvant radiotherapy and/or chemotherapy. In the Seer study, 52.2% were treated with ... The chemotherapy regimens used to treat ICCB have included triple therapy with cyclophosphamide, epirubicin and fluorouracil, ... In more recent studies, virtually all individuals have been treated with adjuvant hormonal therapy drugs, such as letrozole or ... chemotherapy, radiotherapy, and long-term treatment with tamoxifen followed by letrozole. Mo CH, Ackbarkhan Z, Gu YY, Chen G, ...
Stanojevic Z, Djordjevic B, Todorovska I, Lilic V, Zivadinovic R, Dunjic O (2008). "Risk factors and adjuvant chemotherapy in ... If the tumor has spread surgery is cytoreductive followed by radiation therapy and/or chemotherapy. The five years survival was ...
Surgical treatments are typically followed by adjuvant, usually platinum-based, chemotherapy. Radiation therapy has been ... 1991). "Cisplatin-based combination chemotherapy in carcinoma of the fallopian tube". Gynecol Oncol. 42 (2): 156-160. doi: ... the patients with advanced stage disease survived 5 years with a surgical approach followed by cisplatinum-based chemotherapy. ...
For later stages, adjuvant chemotherapy has been shown to improve patient survival. Lymphadenectomy and lymph node chemotherapy ... "Trends in surgery and chemotherapy for women diagnosed with ovarian cancer in the United States, J Clin Oncol, 21 (18) (2003), ... Wright, J.D.; Doan, T.; McBride, R.; Jacobson, J.S.; Hershman, D.L. (2008). "Variability in chemotherapy delivery for elderly ... Zeimet, A.G.; Reimer, D.; Concin, N.; Braun, S.; Marth, C. (2008). "Primary chemotherapy and maintenance therapy in epithelial ...
These micrometastases can be treated with adjuvant chemotherapy and can reduce relapse rates caused by these disseminated cells ... 59 Intensification chemotherapy is identical to consolidation chemotherapy but a different drug than the induction chemotherapy ... Chemotherapy may be given with a curative intent or it may aim to prolong life or to palliate symptoms. Induction chemotherapy ... This type of chemotherapy is used for curative intent.: 55-59 Combined modality chemotherapy is the use of drugs with other ...
"Adjuvant chemoradiotherapy and chemotherapy in resectable pancreatic cancer: a randomised controlled trial". The Lancet. 358 ( ...
... has also been used as adjuvant chemotherapy for curatively resected colorectal cancer patients in China, Japan, and ... Yamamoto M, Arii S, Sugahara K, Tobe T (March 1996). "Adjuvant oral chemotherapy to prevent recurrence after curative resection ... September 2005). "An individual patient data meta-analysis of adjuvant therapy with carmofur in patients with curatively ... Baehring JM, Fulbright RK (May 2008). "Delayed leukoencephalopathy with stroke-like presentation in chemotherapy recipients". ...
"Arginine as an adjuvant to chemotherapy improves clinical outcome in active tuberculosis". European Respiratory Journal. 21 (3 ... Most such patients require adjuvant surgery for any hope of a cure. MDR-TB is widespread in Somalia, where 8.7% of newly ... Antimicrobial Agents and Chemotherapy. 53 (8): 3181-9. doi:10.1128/AAC.01577-08. PMC 2715638. PMID 19451293. Zaw, Myo T.; Emran ... Antimicrobial Agents and Chemotherapy. 43 (7): 1638-43. doi:10.1128/AAC.43.7.1638. PMC 89336. PMID 10390215. Janulionis, E.; ...
... if adjuvant chemotherapy and/or craniospinal irradiation is performed, and just 10% if no adjuvant chemotherapy or craniospinal ... or adjuvant chemotherapy. For non-seminoma, the options include: active surveillance, adjuvant chemotherapy and retroperitoneal ... Adjuvant chemotherapy has been used in malignant melanoma, but there is little hard evidence to use chemotherapy in the ... Dose-dense chemotherapy (DDC) has recently emerged as an effective method of adjuvant chemotherapy administration. DDC uses the ...