Calcinosis cutisSclerodactylyReactive perforating collagenosis: (ILDS L87.100)Dermatomyositis: - (ILDS M33.910)Phosphate binder: Phosphate binders are medications used to reduce the absorption of phosphate and taken with meals and snacks. They are typically used in people with chronic kidney failure (CKF) as they often have difficulty getting rid of the phosphates that get into their blood (i.N-acetylneuraminylgalactosylglucosylceramide b-1,4-N-acetylgalactosaminyltransferase: N-acetylneuraminylgalactosylglucosylceramide beta-1,4-N-acetylgalactosaminyltransferase (, uridine diphosphoacetylgalactosamine-acetylneuraminyl(alpha2->3)galactosyl(beta1->4)glucosyl beta1->4-acetylgalactosaminyltransferase, UDP-N-acetyl-D-galactosamine:N-acetylneuraminyl-2,3-alpha-D-galactosyl-1,4-beta-D-glucosylceramide beta-1,4-N-acetylgalactosaminyltransferase) is an enzyme with system name UDP-N-acetyl-D-galactosamine:N-acetylneuraminyl-(2->3)-alpha-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide 4-beta-N-acetylgalactosaminyltransferase. This enzyme catalyses the following chemical reactionSystemic sclerodermaOsteoporosis circumscripta: Osteoporosis Circumscripta Cranii refers to a highly circumscribed (focal) lytic lesion of the skull bone as seen on X-ray in patients with Paget's disease of bones. This focal lesion can be fairly large.Telangiectasia macularis eruptiva perstans: Telangiectasia macularis eruptiva perstans is persistent, pigmented, asymptomatic eruption of macules usually less than 0.5 cm in diameter with a slightly reddish-brown tinge.Worth syndrome: Worth syndrome, also known as benign form of Worth hyperostosis corticalis generalisata with torus platinus, autosomal dominant osteosclerosis, autosomal dominant endosteal hyperostosis or Worth disease, is a rare autosomal dominant congenital disorder that is caused by a mutation in the LRP5 gene. It is characterized by increased bone density and benign bony structures on the palate.Ulcerative dermatitis: Ulcerative dermatitis is a skin disorder in rodents associated with bacterial growth often initiated by self-trauma due to a possible allergic response. Although other organisms can be involved, bacteria culture frequently shows Staphylococcus aureus.HyperkalemiaBlepharochalasisMilwaukee shoulder syndrome: Milwaukee shoulder syndrome (apatite-associated destructive arthritis) is a rheumatological condition similar to calcium pyrophosphate dihydrate deposition disease (CPPD). It is associated with periarticular or intraarticular deposition of hydroxyapatite crystals.NephrocalcinosisBasal ganglia diseaseSodium hexametaphosphateTour SignalFGF15/19: FGF15/19 refers to two orthologous fibroblast growth factors which share 50% aminoacid identity and have similar functions.Anti-dsDNA antibodies: Anti-dsDNA antibodies are a group of anti-nuclear antibodies and their target antigen is double stranded DNA. Blood tests such as enzyme-linked immunosorbent assay (ELISA) and immunofluorescence are routinely performed to detect anti-dsDNA antibodies in diagnostic laboratories.Beta-glucuronidasePhosphorus deficiency: Phosphorus deficiency is a plant disorder associated with insufficient supply of phosphorus. Phosphorus refers here to salts of phosphates (PO43−), monohydrogen phosphate (HPO42−), and dihydrogen phosphate (H2PO4−).CentromereOsteopontin: Osteopontin (OPN), also known as bone sialoprotein I (BSP-1 or BNSP), early T-lymphocyte activation (ETA-1), secreted phosphoprotein 1 (SPP1), 2ar and Rickettsia resistance (Ric), is a protein that in humans is encoded by the SPP1 gene (secreted phosphoprotein 1). The murine ortholog is Spp1.Five Fingers GroupAutoantibody: An autoantibody is an antibody (a type of protein) produced by the immune system that is directed against one or more of the individual's own proteins. Many autoimmune diseases, (notably lupus erythematosus), are caused by such autoantibodies.Dermal equivalent: The dermal equivalent is an in vitro model of the dermal layer of skin. It is constructed by seeding dermal fibroblasts into a collagen gel.Brain biopsyCalcium signaling: Calcium ions are important for cellular signalling, as once they enter the cytosol of the cytoplasm they exert allosteric regulatory effects on many enzymes and proteins. Calcium can act in signal transduction resulting from activation of ion channels or as a second messenger caused by indirect signal transduction pathways such as G protein-coupled receptors.Nathan W. Levin