Tropic cues involved in growth cone guidanceNeuroregeneration: Neuroregeneration refers to the regrowth or repair of nervous tissues, cells or cell products. Such mechanisms may include generation of new neurons, glia, axons, myelin, or synapses.Onykia robusta: Onykia robusta, also known as the robust clubhook squid and often cited by the older name Moroteuthis robusta,Bolstad, K.S.Axoplasmic transport: Axoplasmic transport, also called axonal transport, is a cellular process responsible for movement of mitochondria, lipids, synaptic vesicles, proteins, and other cell parts (i.e.HSD2 neurons: HSD2 neurons are a small group of neurons in the brainstem which are uniquely sensitive to the mineralocorticosteroid hormone aldosterone, through expression of HSD11B2. They are located within the caudal medulla oblongata, in the nucleus of the solitary tract (NTS).Renshaw cell: Renshaw cells are inhibitory interneurons found in the gray matter of the spinal cord, and are associated in two ways with an alpha motor neuron.Remyelination: Remyelination is the process of propagating oligodendrocyte precursor cells to form oligodendrocytes to create new myelin sheaths on demyelinated axons in the CNS. This is a process naturally regulated in the body and tends to be very efficient in a healthy CNS.Optic nerve tumor: An optic nerve melanocytoma is a tumor made up of melanocytes and melanin. These tumors are typically a benign; they can grow, but rarely transform into a malignancy.Neuromere: Neuromeres are morphologically or molecularly defined transient segments of the early developing brain. Rhombomeres are such segments that make up the rhombencephalon or hindbrain.Oblique dendrite: An oblique dendrite is a dendrite that branches from an apical dendrite which emerge from the apex of a pyramidal cell. Oblique dendrites typically branch one to two times before terminating.Sensory decussation: The sensory decussation or decussation of the lemniscus is a decussation or crossover of axons from the gracile nucleus and cuneate nucleus, which are responsible for fine touch, proprioception and two-point discrimination of the body. The fibres of this decussation are called the internal arcuate fibres and are found at the superior aspect of the closed medulla superior to the motor decussation.Compound muscle action potential: The compound muscle action potential (CMAP) or compound motor action potential is an electromyography investigation (electrical study of muscle function).Semaphorin: Semaphorins are a class of secreted and membrane proteins that act as axonal growth cone guidance molecules. They primarily act as short-range inhibitory signals and signal through multimeric receptor complexes.Wallerian degeneration: Wallerian degeneration is a process that results when a nerve fiber is cut or crushed, in which the part of the axon separated from the neuron's cell body degenerates distal to the injury.Trauma and Wallerian Degeneration, University of California, San Francisco This is also known as anterograde or orthograde degeneration.Collapsin response mediator protein family: Collapsin response mediator protein family or CRMP family consists of five intracellular phosphoproteins (CRMP-1, CRMP-2, CRMP-3, CRMP4, CRMP5) of similar molecular size (60–66 kDa) and high (50–70%) amino acid sequence identity. CRMPs are predominantly expressed in the nervous system during development and play important roles in axon formation from neurites and in growth cone guidance and collapse through their interactions with microtubules.Silent synapse: In neuroscience, a silent synapse is an excitatory glutamatergic synapse whose postsynaptic membrane contains NMDA-type glutamate receptors but no AMPA-type glutamate receptors. These synapses are named "silent" because normal AMPA receptor-mediated signaling is not present, rendering the synapse inactive under typical conditions.Endoneurium: The endoneurium (also called endoneurial channel, endoneurial sheath, endoneurial tube, or Henle's sheath) is a layer of delicate connective tissue around the myelin sheath of each myelinated nerve fiber. Its component cells are called endoneurial cells.Fixation reflex: The fixation reflex is that concerned with attracting the eye on a peripheral object. For example, when a light shines in the periphery, the eyes shift gaze on it.Retinal regeneration: Retinal regeneration deals with restoring retinal function to vertebrates so impaired.Ventricular action potentialInferior longitudinal fasciculus: The inferior longitudinal fasciculus connects the temporal lobe and occipital lobe, running along the lateral walls of the inferior and posterior cornua of the lateral ventricle.Gap-43 protein: Growth Associated Protein 43 also known as GAP43 is a protein that in humans is encoded by the GAP43 gene.Interoceptor: An interoceptor is a sensory receptor that detects stimulus within the body. Examples of stimuli that would be detected by interoceptors include blood pressureCampbell, Neil A.Axotomy: An axotomy is the cutting or otherwise severing of an axon. Derived from axo- (=axon) and -tomy (=surgery).Brain healing: Brain healing is the process that occurs after the brain has been damaged. If an individual survives brain damage, the brain has a remarkable ability to adapt.Saltatory conduction: Saltatory conduction (from the Latin saltare, to hop or leap) is the propagation of action potentials along myelinated axons from one node of Ranvier to the next node, increasing the conduction velocity of action potentials. The uninsulated nodes of Ranvier are the only places along the axon where ions are exchanged across the axon membrane, regenerating the action potential between regions of the axon that are insulated by myelin, unlike electrical conduction in a simple circuit.Low-voltage electron microscope: Low-voltage electron microscope (LVEM) is an electron microscope which operates at accelerating voltages of a few kiloelectronvolts or less. While the low voltage electron microscopy technique will never replace conventional high voltage electron microscopes, it is quickly becoming appreciated for many different disciplines.Horseradish peroxidaseBobby Crush: Bobby Crush (born Robert Nicholas Crush, 23 March 1954) is an English pianist, songwriter, actor and television presenter, originally from Leyton in East London.DiencephalonCats in the United States: Many different species of mammal can be classified as cats (felids) in the United States. These include domestic cat (both house cats and feral), of the species Felis catus; medium-sized wild cats from the genus Lynx; and big cats from the genera Puma and Panthera.Sacral anterior root stimulator: An implantable medical device enabling patients with a spinal cord lesion to empty their bladders.Synapto-pHluorin: Synapto-pHluorin is a genetically encoded optical indicator of vesicle release and recycling. It is used in neuroscience to study transmitter release.Orconectes alabamensis: Orconectes alabamensis, the Alabama crayfish, is a species of freshwater crayfish that lives in Alabama, Mississippi and Tennessee.Morphant: An organism which has been treated with a morpholino antisense oligo to temporarily knock down expression of a targeted gene is called a morphant.Cortical stimulation mapping: Cortical stimulation mapping (often shortened to CSM) is a type of electrocorticography that involves a physically invasive procedure and aims to localize the function of specific brain regions through direct electrical stimulation of the cerebral cortex. It remains one of the earliest methods of analyzing the brain and has allowed researchers to study the relationship between cortical structure and systemic function.Olfactory ensheathing glia: Olfactory ensheathing glia (OEG), also known as olfactory ensheathing cells (OECs) or olfactory ensheathing glial cells, are a type of macroglia (radial glia) found in the nervous system. They are also known as olfactory Schwann cells because they ensheath the non-myelinated axons of olfactory neurons in a similar way to which Schwann cells ensheath non-myelinated peripheral neurons.Drosophila embryogenesis: Drosophila embryogenesis, the process by which Drosophila (fruit fly) embryos form, is a favorite model system for geneticists and developmental biologists studying embryogenesis. The small size, short generation time, and large brood size make it ideal for genetic studies.Dolabella auricularia: Dolabella auricularia, common name the "wedge sea hare" or "Donsol" in the Philippines, is a species of large sea slug, a marine opisthobranch gastropod mollusk in the family Aplysiidae, the sea hares.TBR1: T-box, brain, 1 is a transcription factor protein important in vertebrate embryo development. It is encoded by the TBR1 gene.Reticulon: Reticulons (RTNs in vertebrates and reticulon-like proteins or RNTls in other eukaryotes) are a group of evolutionary conservative proteins residing predominantly in endoplasmic reticulum, primarily playing a role in promoting membrane curvature. In addition reticulons may play a role in nuclear pore complex formation, vesicle formation, and other processes yet to be defined.Benign fasciculation syndrome: Benign fasciculation syndrome (BFS) is a neurological disorder characterized by fasciculation (twitching) of various voluntary muscles in the body. The twitching can occur in any voluntary muscle group but is most common in the eyelids, arms, legs, and feet.ParvalbuminBESS domain: In molecular biology, the BESS domain is a protein domain which has been named after the three proteins that originally defined the domain: BEAF (Boundary element associated factor 32), Suvar(3)7 and Stonewall ). The BESS domain is 40 amino acid residues long and is predicted to be composed of three alpha helices, as such it might be related to the myb/SANT HTH domain.Piriform cortex: In anatomy of animals, the piriform cortex, or pyriform cortex, is a region in the brain, part of the rhinencephalon situated in the telencephalon. The function of the piriform cortex relates to olfaction.Rehabilitation in spinal cord injury: When treating a person with a spinal cord injury, repairing the damage created by injury is the ultimate goal. By using a variety of treatments, greater improvements are achieved, and, therefore, treatment should not be limited to one method.Trochlear nerve: The trochlear nerve,, ) come from Ancient Greek also called the fourth cranial nerve or cranial nerve IV, is a motor nerve] (a [[somatic nervous system|somatic efferent nerve) that innervates only a single muscle: the superior oblique muscle of the eye, which operates through the pulley-like trochlea.Place cellP7C3Temporal analysis of products: Temporal Analysis of Products (TAP), (TAP-2), (TAP-3) is an experimental technique for studyingMicrotubule: Microtubules ([+ tube] + [are a component of the [[cytoskeleton], found throughout the [[cytoplasm. These tubular polymers of tubulin can grow as long as 50 micrometres and are highly dynamic.Periodic current reversalReversal potential: In a biological membrane, the reversal potential (also known as the Nernst potential) of an ion is the membrane potential at which there is no net (overall) flow of that particular ion from one side of the membrane to the other. In the case of post-synaptic neurons, the reversal potential is the membrane potential at which a given neurotransmitter causes no net current flow of ions through that neurotransmitter receptor's ion channel.Chaetopterus: Chaetopterus or the parchment worm or parchment tube worm is a genus of marine polychaete worm that lives in a tube it constructs in sediments or attaches to a rocky or coral reef substrate. The common name arises from the parchment-like appearance of the tubes that house these worms.Olfactory receptor: Olfactory receptors expressed in the cell membranes of olfactory receptor neurons are responsible for the detection of odor molecules. Activated olfactory receptors are the initial player in a signal transduction cascade which ultimately produces a nerve impulse which is transmitted to the brain.
Download our free solidary book to support research on VHL disease