Effects of parasitic worms on the immune system: The effects of parasitic worms, or helminths, on the immune system is a recently emerging topic of study among immunologists and other biologists. Experiments have involved a wide range of parasites, diseases, and hosts.Primary and secondary antibodies: Primary and secondary antibodies are two groups of antibodies that are classified based on whether they bind to antigens or proteins directly or target another (primary) antibody that, in turn, is bound to an antigen or protein.Soil-transmitted helminthiasis: Soil-transmitted helminthiasis (STH) is a type of helminth infections (helminthiasis) caused by different species of roundworms. It is caused specifically by those worms which are transmitted through soil contaminated with faecal matter and are therefore called soil-transmitted helminths.SurfbirdHelminthic therapyMonoclonal antibody therapyIntestinal parasiteTrichuris: Trichuris, often referred to as whipworms (which typically refers to T. trichiura only in medicine, and to any other species in veterinary medicine), is a genus of parasite worms from the roundworm family Trichuridae, which is a type of helminth.Avidity: In the context of biochemistry, avidity refers to the accumulated strength of multiple affinities of individual non-covalent binding interactions, such as between a protein receptor and its ligand, and is commonly referred to as functional affinity. As such, avidity is distinct from affinity, which describes the strength of a single interaction.ATCvet code QP52: ==QP52A Anthelmintics==Anti-idiotypic vaccine: Anti-idiotypic vaccines comprise antibodies that have three-dimensional immunogenic regions, designated idiotopes, that consist of protein sequences that bind to cell receptors. Idiotopes are aggregated into idiotypes specific of their target antigen.Nematode infectionCryptic self epitopes: In immunology, cryptic self epitopes are a source of autoimmunity.CestodaAnti-dsDNA antibodies: Anti-dsDNA antibodies are a group of anti-nuclear antibodies and their target antigen is double stranded DNA. Blood tests such as enzyme-linked immunosorbent assay (ELISA) and immunofluorescence are routinely performed to detect anti-dsDNA antibodies in diagnostic laboratories.AlbendazoleSchistosoma mansoni: Schistosoma mansoni is a significant parasite of humans, a trematode that is one of the major agents of the disease schistosomiasis which is one type of helminthiasis, a neglected tropical disease. The schistosomiasis caused by Schistosoma mansoni is intestinal schistosomiasis.SeroconversionAutoantibody: An autoantibody is an antibody (a type of protein) produced by the immune system that is directed against one or more of the individual's own proteins. Many autoimmune diseases, (notably lupus erythematosus), are caused by such autoantibodies.Filarioidea: The Filarioidea are a superfamily of nematodes (roundworms). The members of this superfamily are known as filarial worms.Protozoan infection: Protozoan infections are parasitic diseases caused by organisms formerly classified in the Kingdom Protozoa. They include organisms classified in Amoebozoa, Excavata, and Chromalveolata.CD4 immunoadhesin: CD4 immunoadhesin is a recombinant fusion protein consisting of a combination of CD4 and the fragment crystallizable region.Plaque reduction neutralization test: The Plaque reduction neutralization test is used to quantify the titre of neutralising antibody for a virus.Coles PhillipsSchistosoma mekongi: Schistosoma mekongi is a trematode, also known as a flatworm or fluke. It is one of the five major schistosomes that account for all human infections, the other four being S.Trifunctional antibody: A trifunctional antibody is a monoclonal antibody with binding sites for two different antigens, typically CD3 and a tumor antigen, making it a type of bispecific monoclonal antibody. In addition, its intact Fc-part can bind to an Fc receptor on accessory cells like conventional monospecific antibodies.Protein primary structure: The primary structure of a peptide or protein is the linear sequence of its amino acid structural units, and partly comprises its overall biomolecular structure. By convention, the primary structure of a protein is reported starting from the amino-terminal (N) end to the carboxyl-terminal (C) end.Coenurosis in humans: Coenurosis is a parasitic infection that results when humans ingest the eggs of dog tapeworm species Taenia multiceps, T. serialis, T.SchistosomiasisNippostrongylus brasiliensis: Nippostrongylus brasiliensis is a gastrointestinal roundworm or nematode that infects rodents, primarily rats. This worm is a widely studied parasite due to its simple life-cycle and its ability to be used in animal models.Single-chain variable fragment: A single-chain variable fragment (scFv) is not actually a fragment of an antibody, but instead is a fusion protein of the variable regions of the heavy (VH) and light chains (VL) of immunoglobulins, connected with a short linker peptide of ten to about 25 amino acids.Huston, J.Raji cell: Raji cell line is the first continuous human cell line from hematopoietic origin. The cell lines produce an unusual strain of Epstein-Barr virus which will both transform cord blood lymphocytes and induce early antigens in Raji cells.Fragment antigen-binding: The fragment antigen-binding (Fab fragment) is a region on an antibody that binds to antigens. It is composed of one constant and one variable domain of each of the heavy and the light chain.Philophthalmus gralliHeterophile: Heterophile antibodies are antibodies induced by external antigens (heterophile antigens).Abzyme: An abzyme (from antibody and enzyme), also called catmab (from catalytic monoclonal antibody), and most often called catalytic antibody, is a monoclonal antibody with catalytic activity. Abzymes are usually raised in lab animals immunized against synthetic haptans, but some natural abzymes can be found in normal humans (anti-vasoactive intestinal peptide autoantibodies) and in patients with autoimmune diseases such as systemic lupus erythematosus, where they can bind to and hydrolyze DNA.Fasciola hepatica: Fasciola hepatica, also known as the common liver fluke or sheep liver fluke, is a parasitic trematode (fluke or flatworm, a type of helminth) of the class Trematoda, phylum Platyhelminthes that infects the livers of various mammals, including humans. The disease caused by the fluke is called fascioliasis or fasciolosis, which is a type of helminthiasis and has been classified as a neglected tropical disease.Necator americanus: Necator americanus is a species of hookworm (a type of helminth) commonly known as the New World hookworm. Like other hookworms, it is a member of the phylum Nematoda.Bithynia fuchsiana: Bithynia fuchsiana is a species of small freshwater snail with a gill and an operculum, an aquatic gastropod mollusk in the family Bithyniidae.Lars Larsen Forsæth: Lars Larsen Forsæth (baptized 9 December 1759 – 12 February 1839) was a Norwegian farmer who served as a representative at the Norwegian Constituent Assembly. Tallak Lindstøl: Stortinget og Statsraadet, Kristiania, 1914.New Zealand rabbitBevacizumabIndex of soil-related articles: This is an index of articles relating to soil.ImmunizationHeterodera schachtii: Heterodera schachtii Heterodera schactii at Nemaplex, University of CaliforniaHeterodera schactii at Knowledge Master (Beet cyst eelworm, Sugarbeet nematode) is a plant pathogenic nematode. It infects more than 200 different plants including economically important crops such as sugar beets, cabbage, broccoli, and radish.Eva Engvall: Eva Engvall, born 1940, is one of the scientists who invented ELISA in 1971.Eva Engvall, The Scientist 1995, 9(18):8Parasitic disease: A parasitic disease is an infectious disease caused or transmitted by a parasite. Many parasites do not cause diseases.Epitope mapping: Epitope mapping is the process of experimentally identifying the binding sites, or ‘epitopes’, of antibodies on their target antigens. Identification and characterization of the binding sites of antibodies can aid in the discovery and development of new therapeutics, vaccines, and diagnostics.History and naming of human leukocyte antigens: Human leukocyte antigens (HLA) began as a list of antigens identified as a result of transplant rejection. The antigens were initially identified by categorizing and performing massive statistical analyses on interactions between blood types.Strongyloides stercoralis: Strongyloides stercoralis is a human pathogenic parasitic roundworm causing the disease strongyloidiasis. Its common name is threadworm.HymenolepiasisStichosome: Stichosome (from Greek stichos (στίχος) = row; soma (σῶµα) = body) is a multicellular organ that is very prominent in some stages of nematodes and consists of a longitudinal series of glandular unicellular cells (stichocytes) arranged in a row along the oesophagus that form the posterior esophageal glands. It opens into the esophageal lumen and apparently functions as a secretory gland and storage organ.Immunoperoxidase: Immunoperoxidase is a type of immunostain used in molecular biology, medical research, and clinical diagnostics. In particular, immunoperoxidase reactions refer to a sub-class of immunohistochemical or immunocytochemical procedures in which the antibodies are visualized via a peroxidase-catalyzed reaction.Ascaris: Ascaris is a genus of parasitic nematode worms known as the "small intestinal roundworms", which is a type of helminth. One species, Ascaris lumbricoides, affects humans and causes the disease ascariasis.Taenia crassiceps: Taenia crassiceps is a parasitic organism, and is a member of the Taenia genus. It is a tapeworm.Hyperimmune globulin: Hyperimmune globulin is similar to intravenous immunoglobulin (IVIG) except that it is prepared from the plasma of donors with high titers of antibody against a specific organism or antigen. Some agents against which hyperimmune globulins are available include hepatitis B, rabies, tetanus toxin, varicella-zoster, etc.Polyclonal B cell response: Polyclonal B cell response is a natural mode of immune response exhibited by the adaptive immune system of mammals. It ensures that a single antigen is recognized and attacked through its overlapping parts, called epitopes, by multiple clones of B cell.
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