... (INN, also known as mithramycin; trade name Mithracin) is an antineoplastic antibiotic produced by Streptomyces ... Majee S, Chakrabarti A (May 1999). "Membrane interaction of an antitumor antibiotic, mithramycin, with anionic phospholipid ...
An analogue of the anthracycline antineoplastic antibiotic doxorubicin. Pirarubicin intercalates into DNA and interacts with ...
"The Toxicologic Evaluation of Marcellomycin-An Antineoplastic Anthracycline Antibiotic". Drug and Chemical Toxicology. 6 (1): ... Most of those components are antitumor agents and anthracycline antibiotics active against Gram-positive bacteria. Bohemic acid ... Chromatographical separation, in addition to the antibiotics pyrromycin and cinerubin A and B, reveals several individual ... The suffix -mycin is conventionally added to indicate antibiotics derived from actinobacteria or fungi. The individual ...
It is an antineoplastic antibiotic and an intercalating agent. Becatecarin (BMS-181176) is a synthetic analog of rebeccamycin. ... The Journal of Antibiotics. 40 (5): 668-78. doi:10.7164/antibiotics.40.668. PMID 3112080. Anizon F, Belin L, Moreau P, Sancelme ... "Isolation and structure of rebeccamycin-a new antitumor antibiotic from Nocardia aerocoligenes". Tetrahedron Letters. 26 (34): ...
... also has antibiotic, antiamoebic, and antimalarial activity. Phase I and II clinical trials were conducted for the ... Bucreantin has attracted interest as a potential antitumor drug because of its antineoplastic activity. It inhibits the ...
... (INN) is a benzoylhydrazone derivative of the anthracycline antineoplastic antibiotic daunorubicin. Zorubicin ...
Bleomycin is an antineoplastic antibiotic drug isolated in 1966 from the actinomycete Streptomyces verticillus. Bleomycin forms ...
... the antibiotic rifampicin has been found to induce MDR1 expression. Experiments in different drug resistant cell lines and ... to ensure their survival against antineoplastic drugs. Antineoplastic resistance, synonymous with chemotherapy resistance, is ... Antineoplastic drugs kill susceptible sub-populations and the tumour mass may shrink as an initial response to the drug, ... Epigenetic modifications in antineoplastic drug resistance play a major role in cancer development and drug resistance as they ...
The antineoplastic Apaziquone. Benzoquinone compounds are a metabolite of paracetamol. Many natural and artificial coloring ... which produces a quinone antibiotic. Another quinone-containing drug is Mecarbinate (dimecarbine), made by the reaction of ...
The evolution of antibiotic resistance in bacteria is iatrogenic as well. Bacterial strains resistant to antibiotics have ... Alkylating antineoplastic agents, for example, cause DNA damage, which is more harmful to cancer cells than regular cells. ... Antiseptics, anesthesia, antibiotics, better surgical techniques, evidence-based protocols and best practices continue to be ... Adverse effects of prescription drugs or vaccines Overuse of drugs (causing, for example, antibiotic resistance in bacteria) ...
Broad categories of medications associated with toxic effects on nerves include: antineoplastic agents, antibiotics, ... While antibiotics are effective at eradicating the bacterium, neurological sequelae of infection must be treated with ... While commonly self-limiting, treatment with antibiotics may hasten resolution of symptoms. Diphtheria, a once common childhood ...
Antibiotics are widely produced and consumed to treat bacterial and fungal diseases. Since antibiotics are only partially ... Antineoplastic drugs are employed during chemotherapy all over the world. They pollute water courses and have 'mutagenic, ... antibiotics from the environment because they could cause generation of antibiotics resistant bacteria and antibiotics ... Residual antibiotics are not easily biodegraded so, they can survive in environments for long periods of time. There are calls ...
A recent study has shown that the anthraquinone component of lac dye also possess antineoplastic or anticancer effects. It is ... including antibiotic, antiviral, antifeedant effect. ... 2016). "Lac dye as a potential anti-neoplastic agent". Journal ...
A noteworthy counterexample, however, includes the antineoplastic antibiotic chloramphenicol, which successfully inhibits ... Due to the differences in their structures, the bacterial 70S ribosomes are vulnerable to these antibiotics while the ... The differences in structure allow some antibiotics to kill bacteria by inhibiting their ribosomes, while leaving human ... Even though mitochondria possess ribosomes similar to the bacterial ones, mitochondria are not affected by these antibiotics ...
... resulting in antibiotic resistance. Furthermore, there is mounting concern over the abuse of antibiotics in the farming of ... Drug resistance is the reduction in effectiveness of a medication such as an antimicrobial or an antineoplastic in treating a ... Bacteria are capable of not only altering the enzyme targeted by antibiotics, but also by the use of enzymes to modify the ... For antibiotic resistance, which represents a widespread problem nowadays, drugs designed to block the mechanisms of bacterial ...
Prophylactic antibiotics are considered to prevent urinary tract infections as those with NBS often have congenital kidney ... In the treatment of malignancies, radiation therapy, alkylating antineoplastic agents, and epipodophyllotoxins are not used, ...
... is an N-methyl derivative of the antineoplastic antibiotic, mitomycin C, which is isolated from various ... Antibiotics, Aziridines, Antineoplastic drugs, Heterocyclic compounds with 4 rings, Indolequinones, Quinones, Indoles, ... As an antineoplastic agent, it is under investigation for the treatment of cancer, particularly head and neck cancer. ...
... an alkylating antineoplastic agent; Hydroxydaunorubicin, also known as doxorubicin: an anthracycline antibiotic that is able to ... This regimen requires the use of prophylactic antibiotics to prevent infectious complications, as well as the use of colony- ...
They are also used to monitor smog and fly ash, and identify effective antibiotics to counter bacterial infections. "Get into a ... and monitoring for possible toxicity of AZT and antineoplastic drugs in patients. Nobel prize winner Robert H. Grubbs uses them ...
Antibiotics, antineoplastic agents, and a variety of CNS-active drugs, especially neuropeptides, are a few examples of ...
Alkylating antineoplastic agents, Alkaloids, Antineoplastic drugs, Biotechnology, Chemotherapeutic adjuvants, Antibiotics). ... a new antitumor antibiotic from Streptomyces". The Journal of Antibiotics. 41 (12): 1915-7. doi:10.7164/antibiotics.41.1915. ... Bizelesin is antineoplastic antibiotic which binds to the minor groove of DNA and induces interstrand cross-linking of DNA, ... They are notable for their extreme cytotoxicity and thus represent a class of exceptionally potent antitumour antibiotics. As ...
The classes of medications that are known to cause diarrhea are laxatives, antacids, heartburn medications, antibiotics, anti- ... Antibiotics can also cause diarrhea, and antibiotic-associated diarrhea is the most common adverse effect of treatment with ... In resource-poor countries, treatment with antibiotics may be beneficial. However, some bacteria are developing antibiotic ... Antibiotics, while rarely used, may be recommended in a few cases such as those who have bloody diarrhea and a high fever, ...
... are anticancer antibiotics of the angucycline class. Mohamed S. Abdelfattah; Madan Kumar Kharel; John Andrew Hitron ... Antineoplastic and immunomodulating drug stubs, Antiinfective agent stubs). ... v t e v t e (Orphaned articles from July 2016, All orphaned articles, Antibiotics, Angucyclines, All stub articles, ... Isolation and Structure Elucidation of C-Glycosylangucycline-Type Antibiotics from Streptomyces sp. KY002". J. Nat. Prod. 71 (9 ...
Plicamycin, an antineoplastic antibiotic produced by Streptomyces plicatus, and Withaferin A, a steroidal lactone from Withania ...
Are the levels of antibiotics in the aquatic environment sufficient to promote antibiotic resistance? What is the effect of ... antineoplastics, and diagnostic contrast media.[2] Personal care products have four classes: fragrances, preservatives, ... Moreover, antibiotic resistant bacteria may also remain in sewage sludge and enter the food chain if the sludge is not ... In the last decade, most research in this area has focused on steroid hormones and antibiotics. There is concern that steroid ...
Bush, Karen (December 2010). "The coming of age of antibiotics: discovery and therapeutic value: Origins of antibiotic drug ... Chemistry, pharmacology, pharmacokinetics, adverse effects and use as an antineoplastic agent". Pharmacotherapy. 4 (2): 61-73. ... cause streptomyces to produce antibiotics. Quinolones are amongst the most commonly used antibiotics for bacterial infections ... These antibiotics are further divided into two group: actinomycin A and actinomycin B. It was shown that both actinomycin A and ...
... is a naturally occurring serine derivative diazo compound with antineoplastic and antibiotic properties deriving from ...
The unifying mechanism of bioactivity in all enediyne antibiotics is the Bergman cyclization, wherein the enediyne portion ... Antineoplastic drugs, Epoxides, Cancer research, Enediynes, Naphthalenes, Experimental drugs, Lactones, Isopropyl compounds, ... Kedarcidin is a chromoprotein antitumor antibiotic first isolated from an Actinomycete in 1992, comprising an ansa-bridged ... Kedarcidin, a new chromoprotein antitumor antibiotic. II. Isolation, purification and physico-chemical properties (Articles ...
... antineoplastic agents MeSH D27.505.954.248.025 - angiogenesis inhibitors MeSH D27.505.954.248.106 - antibiotics, antineoplastic ... antineoplastic agents, alkylating MeSH D27.505.954.248.169 - antineoplastic agents, hormonal MeSH D27.505.954.248.179 - ... MeSH D27.505.519.124 - alkylating agents MeSH D27.505.519.124.035 - antineoplastic agents, alkylating MeSH D27.505.519.155 - ... antibiotics, antifungal MeSH D27.505.954.122.187 - anti-infective agents, local MeSH D27.505.954.122.237 - anti-infective ...
Antibiotics, Allylamines, Diazo compounds, Tripeptides, All stub articles, Antineoplastic and immunomodulating drug stubs). ... The Journal of Antibiotics. 26 (3): 181-183. doi:10.7164/antibiotics.26.181. ISSN 0021-8820. PMID 4205875. De Voe, S. E.; ... The Journal of Antibiotics. 26 (3): 181-183. doi:10.7164/antibiotics.26.181. ISSN 0021-8820. PMID 4205875. Patterson EL, ... Alazopeptin is an antibiotic, with moderate anti-trypanosomal and antitumor activity. It was originally isolated from ...
Antibiotics, Antineoplastic drugs, Pyrrolobenzodiazepines). ... Anthramycin is an active anti-tumor agent and antibiotic. It ... Acute tissue necrosis has also been noted at the injection site of the antibiotic, and side effect of its high cytotoxicity. ... Anthramycin is a pyrrolobenzodiazepine antibiotic with antitumor activity. First derived from the thermophilic actinomycete ... Sartorelli, Alan C.; Johns, David G. (27 November 2013). Antineoplastic and Immunosuppressive Agents. Springer Science & ...