Local anesthetic: Local anesthetic (LA) is a medication that causes reversible absence of pain sensation, although other senses are often affected as well. Also, when it is used on specific nerve pathways (local anesthetic nerve block), paralysis (loss of muscle power) can be achieved as well.Inhalational anaesthetic: An inhalational anaesthetic is a chemical compound possessing general anaesthetic properties that can be delivered via inhalation. They are administered by anaesthetists (a term which includes anaesthesiologists, nurse anaesthetists, and anaesthesiologist assistants) through an anaesthesia mask, laryngeal mask airway or tracheal tube connected to an anaesthetic vaporiser and an anaesthetic delivery system.Theories of general anaesthetic action: A general anaesthetic (or anesthetic) is a drug that brings about a reversible loss of consciousness. These drugs are generally administered by an anaesthetist/anaesthesiologist in order to induce or maintain general anaesthesia to facilitate surgery.HalothaneEnfluraneLidocaine: lignocaineAnesthesia cart: Anesthesia carts are hospital devices used to store tools that are necessary for aid during procedures that require administration of anesthesia. Anesthesia refers to the use of drugs to subdue a patient's mind and prevent him or her from feeling any pain during a surgical operation.EPEBupivacainePropofol infusion syndrome: Propofol infusion syndrome (PRIS) is a rare syndrome which affects patients undergoing long-term treatment with high doses of the anaesthetic and sedative drug propofol. It can lead to cardiac failure, rhabdomyolysis, metabolic acidosis, and kidney failure, and is often fatal.General anaesthesia: General anaesthesia (or general anesthesia) is a medically induced coma and loss of protective reflexes resulting from the administration of one or more general anaesthetic agents. A variety of medications may be administered, with the overall aim of ensuring unconsciousness, amnesia, analgesia, relaxation of skeletal muscles, and loss of control of reflexes of the autonomic nervous system.Penthrox inhaler: The Penthrox inhaler is a hand-held inhaler used for self-administration of methoxyflurane for pain relief. It is manufactured and marketed by Medical Developments International (Melbourne, Victoria, Australia),International Federation of Dental Anesthesiology Societies: The International Federation of Dental Anesthesiology Societies (IFDAS) is a professional association established in 1976. IFDAS is devoted solely to promoting the safe and effective use of sedation and anesthesia by educationally qualified dentists for their patients.Lanicemine: Lanicemine (AZD6765) is a low-trapping NMDA receptor antagonist developed by AstraZeneca, which was being studied for the management of severe and treatment-resistant depression. It was originally developed as a neuroprotective agent, but was redeveloped as an antidepressant following the observation that the NMDA receptor antagonist ketamine has potent antidepressant effects, but also has hallucinogenic side effects which make it unsuitable for use as an antidepressant in most circumstances.Lidocaine/prilocaineNerve blockProcaineNitrous oxide and oxygen: A mix of nitrous oxide 50% and oxygen 50% is a medical analgesic gas, commonly known as Entonox (a registered trademark of BOC) or Nitronox, or colloquially as "gas and air", and is frequently used in pre-hospital care, childbirth and emergency medicine situations by medical professionals such as doctors, nurses, midwives and paramedics.Diethyl ether peroxideDibucaine number: Dibucaine, also known as cinchocaine, is an amino amide local anesthetic. When administered to humans intravenously, it is capable of inhibiting the plasma cholinesterase enzyme.National Dental Board of Anesthesiology: The National Dental Board of Anesthesiology (NDBA) is an American professional association established in 2001 by the American Dental Society of Anesthesiology. Based in Chicago, NDBA is the world's largest national dental board devoted to sedation and anesthesia.Combined spinal and epidural anaesthesia: Combined spinal and epidural anaesthesia (CSE) is a regional anaesthetic technique, which combines the benefits of both spinal anaesthesia and epidural anaesthesia and analgesia. The spinal component gives a rapid onset of a predictable block.Phenol–chloroform extraction: Phenol–chloroform extraction is a liquid-liquid extraction technique in biochemistry and molecular biology for purifying nucleic acids and eliminating proteins. In brief, aqueous samples are mixed with equal volumes of a phenol:chloroform mixture.RomifidineParacervical block: A paracervical block is an anesthetic procedure used in obstetrics and gynecology, in which a local anesthetic is injected into between two to six sites at a depth of 3–7 mm alongside the vaginal portion of the cervix in the vaginal fornices.paracervical block By Robert Nadelberg.Enol etherOhmefentanylConcentration effect: In the study of inhaled anesthetics, the concentration effect is the increase in the rate that the Fa(alveolar concentration)/Fi(inspired concentration) ratio rises as the alveolar concentration of that gas is increased. In simple terms, the higher the concentration of gas administered, the faster the alveolar concentration of that gas approaches the inspired concentration.Org 21465: Org 21465 is a synthetic neuroactive steroid, with sedative effects resulting from its action as a GABAA receptor positive allosteric modulator. It is similar to related drugs such as Org 20599, and was similarly developed as an improved alternative to other sedative steroids such as althesin and allopregnanolone, which despite its superior properties in some respects has not proved to offer enough advantages to be accepted into clinical use.Spinal anaesthesia: Spinal anaesthesia (or spinal anesthesia), also called spinal analgesia, spinal block or subarachnoid block (SAB), is a form of regional anaesthesia involving injection of a local anaesthetic into the subarachnoid space, generally through a fine needle, usually 9 cm long (3.5 inches).Xenon arc lampNonbenzodiazepine: Nonbenzodiazepines (sometimes referred to colloquially as "Z-drugs") are a class of psychoactive drugs that are very benzodiazepine-like in nature. Nonbenzodiazepines pharmacodynamics are almost entirely the same as benzodiazepine drugs and therefore employ similar benefits, side-effects, and risks.IsobutyramideChlorofluorocarbon: A chlorofluorocarbon (CFC) is an organic compound that contains only carbon, chlorine, and fluorine, produced as a volatile derivative of methane, ethane, and propane. They are also commonly known by the DuPont brand name Freon.PinnacleHealth System: $1 billion (2013)Druglikeness: Druglikeness is a qualitative concept used in drug design for how "druglike" a substance is with respect to factors like bioavailability. It is estimated from the molecular structure before the substance is even synthesized and tested.Gas cylinder: A gas cylinder or tank is a pressure vessel used to store gases at above atmospheric pressure. High-pressure gas cylinders are also called bottles.Org 20599Inferior alveolar nerve anaesthesia: Inferior alveolar nerve block (abbreviated to IANB, and also termed inferior alveolar nerve anesthesia or inferior dental block) is a nerve block technique which induces anesthesia (numbness) in the areas of the mouth and face innervated by one of the inferior alveolar nerves which are paired on the left and right side. These areas are the skin and mucous membranes of the lower lip, the skin of the chin, the lower teeth and the labial gingiva of the anterior teeth, all unilaterally to the midline of the side on which the block is administered.Pain scale: A pain scale measures a patient's pain intensity or other features. Pain scales are based on self-report, observational (behavioral), or physiological data.Ammonia volatilization from urea: Urea (46-0-0) accounts for more than fifty percent of the world’s nitrogenous fertilizers.Schwab, G.ThiobutabarbitalDimethoxyethaneMidazolamTemporal analysis of products: Temporal Analysis of Products (TAP), (TAP-2), (TAP-3) is an experimental technique for studyingLevomethadoneBarbiturate dependenceLocal government areas of Scotland: Local government areas covering the whole of Scotland were first defined by the Local Government (Scotland) Act 1889. As currently defined, they are a result, for the most part, of the Local Government etc (Scotland) Act 1994.Chemical restraint: A chemical restraint is a form of medical restraint in which a drug is used to restrict the freedom or movement of a patient or in some cases to sedate a patient. These are used in emergency, acute, and psychiatric settings to control unruly patients who are interfering with their care or who are otherwise harmful to themselves or others in their vicinity.Octanol: Octanols are 8-carbon alcohols. A simple and important member is 1-octanol, with an unbranched chain of carbons.RipazepamProcedural sedation and analgesia: Procedural sedation and analgesia, previously referred to as conscious sedation, is defined as "a technique of administering sedatives or dissociative agents with or without analgesics to induce a state that allows the patient to tolerate unpleasant procedures while maintaining cardiorespiratory function."Quantitative electroencephalography: Quantitative electroencephalography (QEEG) is a field concerned with the numerical analysis of electroencephalography data and associated behavioral correlates.Klumpke paralysisPreventive analgesia: Preventive analgesia is a practice aimed at reducing short- and long-term post-surgery pain. Activity in the body's pain signalling system during surgery produces "sensitization"; that is, it increases the intensity of post-operative pain.Drug interaction: A drug interaction is a situation in which a substance (usually another drug) affects the activity of a drug when both are administered together. This action can be synergistic (when the drug's effect is increased) or antagonistic (when the drug's effect is decreased) or a new effect can be produced that neither produces on its own.History of tracheal intubation: Tracheal intubation (usually simply referred to as intubation), an invasive medical procedure, is the placement of a flexible plastic catheter into the trachea. For millennia, tracheotomy was considered the most reliable (and most risky) method of tracheal intubation.Sciatic nerve: The sciatic nerve (; also called ischiadic nerve, ischiatic nerve) is a large nerve in humans and other animals. It begins in the lower back and runs through the buttock and down the lower limb.AlfadoloneSodium channel: Sodium channels are integral membrane proteins that form ion channels, conducting sodium ions (Na+) through a cell's plasma membrane. They are classified according to the trigger that opens the channel for such ions, i.Malignant hyperthermiaPlacebo-controlled study: Placebo-controlled studies are a way of testing a medical therapy in which, in addition to a group of subjects that receives the treatment to be evaluated, a separate control group receives a sham "placebo" treatment which is specifically designed to have no real effect. Placebos are most commonly used in blinded trials, where subjects do not know whether they are receiving real or placebo treatment.Mayo HospitalElectric pulp test: In dentistry, an electric pulp test ascertains the vitality of a tooth.Kennel clubSufentanilOpioid: Opioids are substances that act on the nervous system in a similar way to opiates such as morphine and codeine. In a medical context the term usually indicates medications that are artificially made rather than extracted from opium.