Anaplastic large-cell lymphoma
... (ALCL) refers to a group of non-Hodgkin lymphomas in which aberrant T cells proliferate ... "UpToDate". Information on Anaplastic Large Cell (Ki-1 / CD-30) Lymphomas from Lymphoma Information Network (Articles with short ... and Molecular Characteristics of Anaplastic Lymphoma Kinase-positive Primary Cutaneous Anaplastic Large Cell Lymphoma" (PDF). ... pcALCL is the second most common lymphoma in the category of Cutaneous T cell lymphoma cutaneous T cell lymphomas that includes ...
Anaplastic lymphoma kinase
... of anaplastic large-cell lymphomas (ALCLs), type ALK-positive anaplastic large cell lymphoma and very rare cases of ALCL type ... Anaplastic lymphoma kinase (ALK) was originally discovered in 1994 in anaplastic large-cell lymphoma (ALCL) cells. ALCL is ... November 2008). "The anaplastic lymphoma kinase controls cell shape and growth of anaplastic large cell lymphoma through Cdc42 ... February 2004). "Nucleophosmin-anaplastic lymphoma kinase of anaplastic large-cell lymphoma recruits, activates, and uses pp60c ...
Mature T-cell lymphoma
Anaplastic large cell lymphoma (ALCL) is a subtype of mature T-cell lymphoma involving T-cells or natural killer (NK) cells, ... Mature T-cell lymphoma is under the category of non-Hodgkin lymphoma. Mature T-cell lymphomas account for 10% to 15% of all ... The common subtypes are angioimmunoblastic T-cell lymphoma, anaplastic large cell lymphoma and peripheral T-cell lymphoma not ... Its common subtypes include angioimmunoblastic T-cell lymphoma, anaplastic large cell lymphoma and peripheral T-cell lymphoma ...
Plasmablastic lymphoma
... anaplastic lymphoma kinase-positive large B-cell lymphoma; and human herpesvirus 8-positive diffuse large B-cell lymphoma, not ... The plasmablastic cells in B-cell lymphomas, including diffuse B-cell lymphomas, chronic lymphocytic leukemia/small lymphocytic ... Unlike PBL, the plasmablastic cells in anaplastic lymphoma kinase-positive large B-cell lymphoma strongly express the product ... which they termed plasmablastic lymphoma, that had some features of a diffuse large B-cell lymphoma but unlike this lymphoma ...
Carlo Gambacorti-Passerini
"Crizotinib in Anaplastic Large Cell Lymphoma". N. Engl. J. Med. 364 (8): 775-776. doi:10.1056/nejmc1013224. PMID 21345110. ... The events which led to the discovery of crizotinib for the treatment of ALK+ lymphomas became part of a novel entitled "Tu ... 2014). "Crizotinib in advanced, chemoresistant anaplastic lymphoma kinase-positive lymphoma patients". J Natl Cancer Inst. 106 ... He is also the first researcher who (in June 2010) successfully treated a patient affected by ALK+ lymphoma with an ALK ...
Enteropathy-associated T-cell lymphoma
Hapgood G, Savage KJ (July 2015). "The biology and management of systemic anaplastic large cell lymphoma". Blood. 126 (1): 17- ... Chan JY, Lim ST (April 2018). "Novel findings from the Asian Lymphoma Study Group: focus on T and NK-cell lymphomas". ... Enteropathy-associated T-cell lymphoma (EATL), previously termed enteropathy-associated T-cell lymphoma, type I and at one time ... Lymphoma Working Party of the EBMT (2013). "Autologous stem cell transplantation for enteropathy-associated T-cell lymphoma: A ...
Monomorphic epitheliotropic intestinal T cell lymphoma
Xing X, Feldman AL (January 2015). "Anaplastic large cell lymphomas: ALK positive, ALK negative, and primary cutaneous". ... Anaplastic large cell lymphoma, ALK positive (ALCL,ALK+): ALCL,ALK+ is a subtype of anaplastic large cell lymphoma. It commonly ... Peripheral T-cell lymphoma not otherwise specified (PTCL-NOS): PTCL-NOS is a heterogenous group of T cell lymphomas that ... Monomorphic epitheliotropic intestinal T cell lymphoma (MEITL) (formerly termed enteropathy-associated T cell lymphoma, type II ...
CD30
... is associated with anaplastic large cell lymphoma. It is expressed in embryonal carcinoma but not in seminoma and is thus ... of CD30-positive B cell lymphomas Various types of CD30-positive T cell lymphomas CD30-positive cases of the NK cell lymphoma, ... "FDA approves Brentuximab vedotin for the treatment of adult patients with primary cutaneous anaplastic large cell lymphoma". ... after failure of at least 1 multiagent chemotherapy regimen Primary cutaneous anaplastic large cell lymphoma (pcALCL) or CD30- ...
ALK+ large B-cell lymphoma
... aggressive large B-cell process that shows ALK expression.: 378 It is distinct from anaplastic large cell lymphoma, a T-cell ... 2010). "Chapter 20". Non-Hodgkin Lymphomas (2nd ed.). Lippincott Williams & Wilkins. ISBN 9780781791168. Laurent C, Do C, ... "Anaplastic lymphoma kinase-positive large B-cell lymphoma: an underrecognized aggressive lymphoma". Adv Hematol. 2012: 529572. ... 2009). "Anaplastic lymphoma kinase-positive diffuse large B-cell lymphoma: a rare clinicopathologic entity with poor prognosis ...
Non-Hodgkin lymphoma
... associated with anaplastic large cell lymphoma. Familial lymphoid cancer is rare. The familial risk of lymphoma is elevated for ... also known as non-Hodgkin's lymphoma, is a group of blood cancers that includes all types of lymphomas except Hodgkin lymphomas ... extranodal NK-T-cell lymphoma and diffuse large B-cell lymphoma. Human T-cell leukemia virus: associated with adult T-cell ... Hepatitis C virus: associated with splenic marginal zone lymphoma, lymphoplasmacytic lymphoma and diffuse large B-cell lymphoma ...
Peripheral T-cell lymphoma not otherwise specified
June 2000). "Autologous stem cell transplantation for anaplastic large-cell lymphomas: results of a prospective trial". Br. J. ... Peripheral T-cell lymphoma not otherwise specified (PTCL-NOS), is a subtype of peripheral T-cell lymphoma. Peripheral T-cell ... PTCL is a type of non-Hodgkin's lymphoma (NHL). PTCL specifically affects T-cells rather than B-cells, and results when T-cells ... "Cytologic findings of peripheral T-cell lymphoma (PTCL) with high epitheloid cell content (Lennert's lymphoma) in imprint smear ...
Subcutaneous T-cell lymphoma
June 2000). "Autologous stem cell transplantation for anaplastic large-cell lymphomas: results of a prospective trial". Br. J. ... Subcutaneous panniculitis-like T-cell lymphoma, is a subtype of Peripheral T-cell lymphoma. Peripheral T-cell lymphoma (PTCL) ... Subcutaneous Panniculitis-like T-cell Lymphoma, as with other types of T-cell lymphoma, was treated similarly to B-cell ... Subcutaneous T-cell lymphoma (also known as a "panniculitis-like T-cell lymphoma") is a cutaneous condition that most commonly ...
Reed-Sternberg cell
... and very rarely in other types of non-Hodgkin lymphomas. Anaplastic large cell lymphoma may show RS-like cells as well. They ... Seen against a sea of B cells, they give the tissue a moth-eaten appearance. Reed-Sternberg cells are large (30-50 microns) and ... Despite having the genetic signature of a B cell, the Reed-Sternberg cells of classical Hodgkin lymphoma fail to express most B ... The presence of these cells is necessary in the diagnosis of Hodgkin lymphoma - the absence of Reed-Sternberg cells has very ...
Large-cell lymphoma
Anaplastic large-cell lymphoma is an example of a large-cell lymphoma that involves T cells. Of the large-cell T-cell lymphomas ... "large-cell lymphoma" under "Diffuse large B cell lymphoma". Many other B-cell lymphomas feature large cells:[citation needed] ... large-cell lymphoma Immunoblastic lymphoma Intravascular large-cell lymphoma Primary mediastinal B-cell lymphoma T-cell-rich B- ... Other groups of lymphomas in this system are the small-cell lymphomas and mixed-cell lymphomas. Diffuse large B-cell lymphoma ...
Cutaneous T-cell lymphoma
... lymphoma Subcutaneous T-cell lymphoma Angiocentric lymphoma Blastic NK-cell lymphoma Primary cutaneous anaplastic large-cell ... Unlike most non-Hodgkin lymphomas (which are generally B-cell-related), CTCL is caused by a mutation of T cells. The cancerous ... and Molecular Characteristics of Anaplastic Lymphoma Kinase-positive Primary Cutaneous Anaplastic Large Cell Lymphoma". The ... cutaneous large T-cell lymphoma Pleomorphic T-cell lymphoma Lennert ...
Breast implant
"Breast Implant Associated Anaplastic Large Cell Lymphoma (BIA-ALCL) Archived 2017-03-26 at the Wayback Machine" (2017). Clemens ... "Breast Implants: Reports of Squamous Cell Carcinoma and Various Lymphomas in Capsule Around Implants: FDA Safety Communication ... The FDA has identified that breast implants may be associated with a rare form of cancer called anaplastic large-cell lymphoma ... Cordeiro, Peter (20 Jan 2020). "Risk of breast implant associated anaplastic large cell lymphoma (BIA-ALCL) in a cohort of 3546 ...
RNASET2
... rearrangement.RNASET2 has been reported as a tumour associated antigen in anaplastic large cell lymphoma and other lymphomas. ... An autoantigen in anaplastic large cell lymphoma identified by protein array analysis". J Proteomics. 75 (17): 5279-5292. doi: ... An autoantigen in anaplastic large cell lymphoma identified by protein array analysis". J Proteomics. 75 (17): 5279-5292. doi: ...
IL2RA
November 2004). "Elevated serum-soluble interleukin-2 receptor levels in patients with anaplastic large cell lymphoma". Blood. ... IL2RA protein can be expressed in many types of neoplastic cells, such as in most B-cell neoplasms, T-cell lymphomas, some ... It can also be found on activated B cells, NK (natural killer) cells, thymocytes, and some myeloid lineage cells (e.g. ... FoxP3+ regulatory T cells in mice, and it has been found that a large proportion of resting memory T cells constitutively ...
Interleukin 9
The analysis of IL-9 expression in different types of tumours such as Large cell anaplastic lymphoma (LCAL) and Hodgkin's ... "Interleukin-9 expression in human malignant lymphomas: unique association with Hodgkin's disease and large cell anaplastic ... IL-9 is produced by variety of cells like mast cells, NKT cells, Th2, Th17, Treg, ILC2, and Th9 cells in different amounts. ... unique association with Hodgkin's disease and large cell anaplastic lymphoma". Blood. 78 (5): 1311-7. doi:10.1182/blood.V78.5. ...
Günter Burg
Pyogenic lymphoma of the skin: a peculiar variant of primary cutaneous neutrophil-rich CD30+ anaplastic large-cell lymphoma. Br ... EORTC Cutaneous Lymphoma Group (1975) International Society for Cutaneous Lymphomas (ISCL) (1991) Schweizer Gesellschaft für ... and Hodgkin cell specific antigen on atypical cells in lymphomatoid papulosis. 2nd Internat. Conference on Malignant Lymphoma. ... A.; Wiede, J. (1991). A Subcutaneous Delta-Positive T-Cell Lymphoma That Produces Interferon Gamma. N. Engl J Med 325:1078-1081 ...
T-cell lymphoma
Angioimmunoblastic T-cell lymphoma (AITL): Aggressive form of T-cell lymphoma.[citation needed] Anaplastic large cell lymphoma ... Primary intestinal T-cell lymphomas Enteropathy-associated T-cell lymphoma (EATL) Monomorphic epitheliotropic intestinal T cell ... The diagnosis of T-cell lymphoma varies largely between the subtypes. Some subtypes like anaplastic large-cell lymphoma have an ... ALK-positive anaplastic large cell lymphoma: an aggressive, systemic ALCL that strongly expresses anaplastic lymphoma kinase, i ...
TFG (gene)
... is a new partner of ALK in anaplastic large cell lymphoma producing two structurally different TFG-ALK translocations". Blood. ... "Diversity of genomic breakpoints in TFG-ALK translocations in anaplastic large cell lymphomas: identification of a new TFG-ALK( ... "A requirement for caveolin-1 and associated kinase Fyn in integrin signaling and anchorage-dependent cell growth". Cell. 94 (5 ... HepG2 cells". The Journal of Biological Chemistry. 275 (27): 20880-6. doi:10.1074/jbc.M905410199. PMID 10764799. Slack BE (Jun ...
Diffuse large B-cell lymphoma
... features that may mimic the Reed-Sternberg cells of Hodgkin disease or the neoplastic cells of anaplastic large cell lymphoma ... "EBV-positive large B-cell lymphomas in young patients: a nodal lymphoma with evidence for a tolerogenic immune environment". ... HHV8-positive diffuse large B-cell lymphoma, NOS (HHV8+ DLBCL, NOS; also termed HHV8-positive diffuse large B-cell lymphoma [ ... Primary mediastinal large B-cell lymphoma (PMBL), also termed primary mediastinal (thymic) large B-cell lymphoma, is a DLBCL in ...
ALK inhibitor
NPM-ALK is a different variation/fusion of ALK that drives anaplastic large-cell lymphomas (ALCLs) and is the target of other ... Anaplastic Lymphoma Kinase (ALK)-Positive, Non-Small Cell Lung Cancer" at ClinicalTrials.gov Clinical trial number NCT03779191 ... Of Care In Patients With Advanced Non-Small Cell Lung Cancer With A Specific Gene Profile Involving The Anaplastic Lymphoma ... ALK inhibitors are anti-cancer drugs that act on tumours with variations of anaplastic lymphoma kinase (ALK) such as an EML4- ...
Diffuse large B-cell lymphoma associated with chronic inflammation
EBV+ Burkitt lymphoma, EBV+ Hodgkin lymphoma, and the EBV+ diffuse large B-cell lymphomas which include as a subtype, DLBCL-CI ... anaplastic (i.e. poorly differentiated), cells that are arranged in a diffuse pattern. Most of these large cells should be B- ... "Diffuse Large B-Cell Lymphoma Arising within Ileal Neobladder: An Expanding Spectrum of Diffuse Large B-Cell Lymphoma ... Diffuse large B-cell lymphoma associated with chronic inflammation (DLBCL-CI) is a subtype of the Diffuse large B-cell ...
Primary testicular diffuse large B-cell lymphoma
... extranodal NK/T-cell lymphoma, nasal type, peripheral T-cell lymphoma, activin receptor-like kinase-1-negative anaplastic large ... is a variant of the diffuse large B-cell lymphomas (DLBCL). DLBCL are a large and diverse group of B-cell malignancies with the ... Primary testicular diffuse large B-cell lymphoma (PT-DLBCL), also termed testicular diffuse large B-cell lymphoma and diffuse ... Other forms of PTL include testicular mantle cell lymphoma, extranodal marginal zone B cell lymphoma, ...
Peripheral T-cell lymphoma
... type T-cell lymphoma Subcutaneous panniculitis-like T-cell lymphoma Anaplastic large cell lymphoma Peripheral T-cell lymphoma- ... Examples include: Cutaneous T-cell lymphomas Angioimmunoblastic T-cell lymphoma Extranodal natural killer/T-cell lymphoma, ... cutaneous T-cell lymphomas are classified separately. "Peripheral T-Cell Lymphoma". Lymphoma Research Foundation. Retrieved ... Peripheral T-cell lymphoma refers to a group of T-cell lymphomas that develop away from the thymus[citation needed] or bone ...
T cell
Extranodal T cell lymphoma Cutaneous T cell lymphomas: Sézary syndrome and Mycosis fungoides Anaplastic large cell lymphoma ... Cytotoxic T cells (TC cells, CTLs, T-killer cells, killer T cells) destroy virus-infected cells and tumor cells, and are also ... Overall, there are three large populations of unconventional T cells: NKT cells, MAIT cells, and gammadelta T cells. Now, their ... T helper cells (TH cells) assist other lymphocytes, including the maturation of B cells into plasma cells and memory B cells, ...
Lymphoma
... anaplastic large cell lymphoma Lymphomatoid papulosis Peripheral T-cell lymphoma not otherwise specified Most common T cell ... Lymphoma classification update: T-cell lymphomas, Hodgkin lymphoma, and histiocytic/dendritic cell neoplasms. Expert Rev ... large B-cell lymphoma ALK+ large B-cell lymphoma Plasmablastic lymphoma Primary effusion lymphoma Large B-cell lymphoma arising ... Burkitt lymphoma; large B cell lymphoma, not otherwise specified; diffuse large B cell lymphoma associated with chronic ...
WHO classification of tumours of the central nervous system
9.1.2.1 MALT lymphoma of the dura 9.1.2.2 Other low-grade B-cell lymphomas of the CNS 9.1.2.3 Anaplastic large cell lymphoma ( ... 1 Meningeal melanocytoma and meningeal melanoma 9.1 Lymphomas 9.1.1 CNS lymphomas 9.1.1.1 Primary diffuse large B-cell lymphoma ... CNS lymphoma 9.1.1.3 Lymphomatoid granulomatosis 9.1.1.4 Intravascular large B-cell lymphoma 9.1.2 Miscellaneous rare lymphomas ... 9.1.2.4 T-cell and NK/T-cell lymphomas 9.2 Histiocytic tumors 9.2.1 Erdheim-Chester disease 9.2.2 Rosai-Dorfman disease 9.2.3 ...