BAHD acyltransferase
Members of this enzyme family typically share two conserved amino acid motifs. The first motif, or string of consecutive amino ... The second conserved motif is DFGWG (Aspartic acid, Phenylalanine, Glycine, Tryptophan, Glycine) and it is typically found near ... Phylogenetic analysis using full-length amino acid sequences of functionally characterized BAHD enzymes by D'Auria (2006) and ... Aspartic acid) and it is typically found in the central region of the protein. The Histidine in this motif has also been shown ...
KKXX (amino acid sequence)
v t e (Amino acids, Amino acid motifs, All stub articles, Molecular biology stubs). ... any amino acid X- any amino acid ER retention KDEL (amino acid sequence) COPI Signal peptide Protein targeting Martin J. ... KKXX and for some proteins XKXX is a target peptide motif located in the C terminus in the amino acid structure of a protein ... The abbreviation KKXX is formed by the corresponding standard abbreviations for lysine (K) and any amino acid (X). This letter ...
Pentatricopeptide repeat
v t e (Protein pages needing a picture, Amino acid motifs, All stub articles, Molecular biology stubs). ... The pentatricopeptide repeat (PPR) is a 35-amino acid sequence motif. Pentatricopeptide-repeat-containing proteins are a family ... They are distinguished by the presence of tandem degenerate PPR motifs and by the relative lack of introns in the genes coding ...
Calmodulin 1
Calmodulin contains 149 amino acids and has 4 calcium-binding EF hand motifs. Its functions include roles in growth and the ... Li Z, Sacks DB (Feb 2003). "Elucidation of the interaction of calmodulin with the IQ motifs of IQGAP1". J. Biol. Chem. 278 (6 ...
Glycine receptor
... identification of amino acid sequence motifs governing subunit stoichiometry". Neuron. 11 (6): 1049-56. doi:10.1016/0896-6273( ... The receptor can be activated by a range of simple amino acids including glycine, β-alanine and taurine, and can be selectively ... The glycine receptor (abbreviated as GlyR or GLR) is the receptor of the amino acid neurotransmitter glycine. GlyR is an ...
KDEL (amino acid sequence)
Articles with short description, Short description matches Wikidata, Amino acids, Amino acid motifs, Peptide sequences). ... H-Histidine D-Aspartic acid E-Glutamic acid L-Leucine Three letter code is: His-Asp-Glu-Leu. ER retention KKXX (amino acid ... KDEL is a target peptide sequence in mammals and plants located on the C-terminal end of the amino acid structure of a protein ... The abbreviation KDEL is formed by the corresponding letters to each amino acid. This letter system was defined by the IUPAC ...
Gluten immunochemistry
McLachlan A, Cullis PG, Cornell HJ (October 2002). "The use of extended amino acid motifs for focussing on toxic peptides in ... The IRP lies within a 25 amino-acid long region that is resistant to pancreatic proteases. The 25mer is also resistant to Brush ... HLA-DQ proteins present polypeptide regions of proteins of about 9 amino acids and larger in size (10 to 14 residues in ... Α2-gliadin differs from the other α-gliadins, specifically because it contains an insert of 14 amino acids. This particular ...
Fig4
The Sac1 phosphatase domain encompasses approximately 400 amino acids and consists of seven conserved motifs. It harbors the ... In humans, the FIG4 gene localizes on chromosome 6 and encodes a Sac3 protein of 907 amino acids. Sac3 is characterized as a ...
Catenin beta-1
Peifer M, Berg S, Reynolds AB (March 1994). "A repeating amino acid motif shared by proteins with diverse cellular roles". Cell ... Liu J, Xing Y, Hinds TR, Zheng J, Xu W (June 2006). "The third 20 amino acid repeat is the tightest binding site of APC for ... First, they might reach or even surpass the length of 30 amino acids in length, and contact the ARM domain on an excessively ... There is one requirement, though: substrates of GSK3 need to be pre-phosphorylated four amino acids downstream (C-terminally) ...
Farnesyltransferase
The last three amino acids of the CaaX motif are removed later. There are four binding pockets in FTase, which accommodate the ... is an aliphatic amino acid, and 'X' is variable). The carboxyl-terminal amino acid (X) discriminates FTase's targets from those ... last four amino acids on the carboxyl-terminus of a protein. Only those with a suitable CaaX motif can bind ('C' is Cysteine, ' ... Farnesyltransferase (FTase) adds a 15-carbon isoprenoid called a farnesyl group to proteins bearing a CaaX motif: a four-amino ...
Cordon-bleu protein
The WH2 domain is an ~18-21 amino acids actin-binding motif. This domain was first recognized as an essential element for the ... The human COBL gene encodes a 1261-amino acid protein with a mass of about 136 kDa. The mouse protein is 1337 amino acids long ... Cobl Homology domains contain three motifs following the consensus KrRAPpPP (first described as "KRAP" motif of unknown ... The WH2 motif in WASp recruits ATP-G-actin that binds to either Arp2 or Arp3 to complete the formation of a trimeric actin ...
RAB2B
It has a motif domain between the amino acids 35 and 43. Due to the alternative splicing, two isoforms of this same protein ... Isoform 2 consists just of 151 amino acids, having a mass of 16,667 Da. Small GTPases of the RAB superfamily are recognized as ... Even though these RAB family proteins are highly homologous to each other (RAB2A and RAB2B have 85.8% amino acid identity), the ...
Armadillo repeat
Peifer M, Berg S, Reynolds AB (1994). "A repeating amino acid motif shared by proteins with diverse cellular roles". Cell. 76 ( ... Eukaryotic Linear Motif resource motif class TRG_NLS_Bipartite_1 Eukaryotic Linear Motif resource motif class TRG_NLS_MonoCore_ ... 2 Eukaryotic Linear Motif resource motif class TRG_NLS_MonoExtC_3 Eukaryotic Linear Motif resource motif class TRG_NLS_MonoExtN ... An armadillo repeat is a characteristic, repetitive amino acid sequence of about 42 residues in length that is found in many ...
Ornithine transcarbamylase
SMG stands for the conserved amino acid motif of Ser-Met-Gly. Upon closure, these residues interact with L-ornithine. The ... Orotic acid is a product of this pathway. Increased levels of orotic acid in urine can be an indicator that a patient is ... Postranscriptional modification leaves the mature peptide with 322 amino acids and a weight of 36.1 kD. The protein is located ... Anabolic OTC facilitates the sixth step in the biosynthesis of the amino acid arginine in prokaryotes. In contrast, mammalian ...
Cytokine receptor
... whose members have certain conserved motifs in their extracellular amino-acid domain. The IL-2 receptor belongs to this chain, ...
TGF alpha
The EGF receptor is characterized by having an extracellular domain that has numerous amino acid motifs. EGFR is essential for ... TGF-α is synthesized internally as part of a 160 (human) or 159 (rat) amino acid transmembrane precursor. The precursor is ... 50 amino acids of TGF-α, and a 35-residue-long cytoplasmic domain. In its smallest form, TGF-α has six cysteines linked ... TGF-α has been shown to inhibit gastric acid secretion. TGF-α can be produced in macrophages, brain cells, and keratinocytes. ...
RNA-dependent RNA polymerase
The catalytic center is formed by several motifs containing a number of conserved amino acid residues.[citation needed] ... Motif A (D-x(4,5)-D) and motif C (GDD) are spatially juxtaposed; the aspartic acid residues of these motifs are implied in the ... Birnaviral RNA replicase is unique in that it lacks motif C (GDD) in the palm. Mononegaviral RdRp (PDB 5A22) has been ... This RNA-directed RNA polymerase possesses a number of short regions and motifs homologous to other RNA-directed RNA ...
Nucleoprotein
For example, RNP in snRNPs have an RNA-binding motif in its RNA-binding protein. Aromatic amino acid residues in this motif ... they provide a rough model of the structure which allows for predictions of the identity of significant amino acids and ... This nucleic acid binding is strengthened by electrostatic attraction between the positive lysine side chains and the negative ... Lysine residues in the helical portion of RNA-binding proteins help to stabilize interactions with nucleic acids. ...
UBA protein domain
UBA domains have a common sequence motif of approximately 45 amino acid residues. They fold into three-helix bundle structures ... Hofmann K, Bucher P (May 1996). "The UBA domain: a sequence motif present in multiple enzyme classes of the ubiquitination ...
C19orf44
There is also a predicted sumoylation motif from amino acid 212 to 221. C19orf44 is predicted to be localized in the nucleus or ... The amino acid sequence for C19orf44 was found to be serine rich using tools on EMBL-EBI. Additionally, there is a domain of ... It contains 10 exons that code for a 657 amino acid protein. There are 7 splice variants that exist for C19orf44. C19orf44 is ... located from amino acid 474 to 641. C19orf44 has experimentally determined phosphorylation sites at the S114 and S213 positions ...
Cyclic di-GMP
These proteins have either an EAL or an HD-GYP amino acid motif. Processes that are known to be regulated by cyclic di-GMP, at ... These proteins typically have a characteristic GGDEF motif, which refers to a conserved sequence of five amino acids. ... 1987). "Regulation of cellulose synthesis in Acetobacter xylinum by cyclic diguanylic acid". Nature. 325 (6101): 279-281. doi: ...
C6orf163
... contains a predicted leucine zipper motif from amino acids 247 to 269. This motif is typically involved in DNA binding ... The human C6orf163 protein is 329 amino acids long and has a molecular weight of 38 kDa. Its predicted isoelectric point is ... C6orf163 has a nuclear localization signal from amino acids 310 to 316. Antibody staining has shown C6orf163 to be localized to ... a tool for the prediction of sumoylation sites and SUMO-interaction motifs". Nucleic Acids Research. 42 (W1): W325-W330. doi: ...
RGS18
This protein contains a conserved 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of ...
List of protein subcellular localization prediction tools
... sequence motifs and amino acid composition". Bioinformatics. 22 (10): 1158-65. doi:10.1093/bioinformatics/btl002. PMID 16428265 ... predicting subcellular localization of proteins based on a new representation of sequences using amino acid indices". Amino ... Du P, Cao S, Li Y (November 2009). "SubChlo: predicting protein subchloroplast locations with pseudo-amino acid composition and ... Tusnády, Gábor E.; Simon, István (Oct 1998). "Principles governing amino acid composition of integral membrane proteins: ...
LRRN3
They are common in protein-protein interaction motifs and are typically 20-29 amino acids in length. All major classes of LRRs ... The LRRN3 protein is 708 amino acids in length. The molecular weight of this protein is 79,424 Daltons, with an isoelectric ... Leucine-rich repeats are unusually rich in the hydrophobic amino acid leucine. ...
C4orf36
It contains a divalent cation tolerance protein CutA motif from amino acids 57-88. No transmembrane domains or N-terminal ... Chemically significant amino acid changes in conserved regions of the c4orf36 protein were found with NCBI SNPGeneView. GRCh38 ... C4orf36 encodes a 117 amino acid protein with a molecular weight of 13.28 kDa and an isoelectric point of 9.54. ... "GenomeNet MOTIF Search". GenomeNet. Archived from the original on 2011-08-17. "PSORTII Prediction". PSORTII. Archived from the ...
Ptc1
This recruitment takes place via a 4 amino acid motif in the Ste5 phosphosites. Ptc1 is also involved in regulating the osmotic ...
Plasmodium gallinaceum
This 15-amino acid motif is one found by the original Dame et al., 1984 discovery of CSP which contains the 5-length CSP Region ... however the antibody's binding is inhibited by a particular CSP motif, suggesting antibody efficacy is due to its anti-CSP ...
C16orf46
A coronavirus cleavage site is predicted at the 235 amino acid position. There are also tyrosine motif locations between amino ... The full C16orf46 protein is 417 amino acids long. It has no isoforms, and its most distant ortholog, Rhincodon typus (whale ... acids 42-45 and 251-252. mRNA folding on the 5' UTR predicts a stem loop twice in the area between base pairs 47-90. C16orf46 ...
Immunoreceptor tyrosine-based inhibitory motif
S is the amino acide Serine, I is the amino acid Isoleucine, and V is the amino acid Valine. ITIMs recruit SH2 domain- ... ITIM motifs are defined as six amino acid signature with the consensus sequence S/I/V/LxYxxL/V, where x stands for any amino ... Muta T, Kurosaki T, Misulovin Z, Sanchez M, Nussenzweig MC, Ravetch JV (March 1994). "A 13-amino-acid motif in the cytoplasmic ... An immunoreceptor tyrosine-based inhibitory motif (ITIM), is a conserved sequence of amino acids that is found intracellularly ...