HIV Vaccine Trials Network: The HIV Vaccine Trials Network (HVTN) is a non-profit organization which connects physicians and scientists with activists and community educators for the purpose of conducting clinical trials seeking a safe and effective HIV vaccine. Collaboratively, research professionals and laypeople review potential vaccines for safety, immune response, and efficacy.Reverse vaccinology: Reverse vaccinology is an improvement on vaccinology that employs bioinformatics, pioneered by Rino Rappuoli and first used against Serogroup B meningococcus.Pizza et al.Naked DNA: Naked DNA is histone-free DNA that is passed from cell to cell during a gene transfer process called transformation or transfection. In transformation, purified or naked DNA is taken up by the recipient cell which will give the recipient cell a new characteristic or phenotype.TwinrixImmunization during pregnancy: Immunization during pregnancy, that is the administration of a vaccine to a pregnant woman, is not a routine event as it is generally preferred to administer vaccines either prior to conception or in the postpartum period. When widespread vaccination is used, the risk for an unvaccinated pregnant patient to be exposed to a related infection is low, allowing for postponement, in general, of routine vaccinations to the postpartum period.Natural transfer: The natural transfer (hypothesis or theory), in reference to the HIV/AIDS pandemic, states that humans first received HIV by contact with primates, presumably from a fight with a Chimpanzee during hunting or consumption of primate meat, and became contaminated with simian immunodeficiency virus (SIV). According to the 'Hunter Theory', the virus was transmitted from a chimpanzee to a human when a bushmeat hunter was bitten or cut while hunting or butchering an animal.VaccinationPeptide vaccine: A peptide vaccine is any peptide which serves to immunize an organism against a pathogen. Peptide vaccine are often synthetic and mimic naturally occurring proteins from pathogens.Conjugate vaccine: A conjugate vaccine is created by covalently attaching a poor (polysaccharide) antigen to a carrier protein (preferably from the same microorganism), thereby conferring the immunological attributes of the carrier to the attached antigen.Vpx: Vpx is a virion-associated protein encoded by human immunodeficiency virus type 2 HIV-2 and most simian immunodeficiency virus (SIV) strains, but that is absent from HIV-1. It is similar in structure to the protein Vpr that is carried by SIV and HIV-2 as well as HIV-1.Adult-onset immunodeficiency syndrome: Adult-onset immunodeficiency syndrome is a provisional name for a newly diagnosed immunodeficiency illness. The name is proposed in the first public study to identify the syndrome.Plaque reduction neutralization test: The Plaque reduction neutralization test is used to quantify the titre of neutralising antibody for a virus.CervarixMeningococcal vaccineEnvelope glycoprotein GP120: Envelope glycoprotein GP120 (or gp120) is a glycoprotein exposed on the surface of the HIV envelope. The 120 in its name comes from its molecular weight of 120 kDa.Management of HIV/AIDS: The management of HIV/AIDS normally includes the use of multiple antiretroviral drugs in an attempt to control HIV infection. There are several classes of antiretroviral agents that act on different stages of the HIV life-cycle.AS04: AS04 (Aka. "Adjuvant System 04") is a trade name for combination of adjuvants used in various vaccine product by GlaxoSmithKline (GSK), in particular the Fendrix Hepatitis B vaccine.Pertussis vaccineImmunizationDenise Faustman: Denise L. Faustman, (born 1958) is a U.Cholera vaccineTyphoid vaccineSmallpox demon: or smallpox devil is a demon which was believed to be responsible for causing smallpox in medieval Japan. In those days, people tried to appease the smallpox demon by assuaging his anger, or they tried to attack the demon since they had no other effective treatment for smallpox.MVA85A: MVA85A (modified vaccinia Ankara 85A) is a new-generation vaccine against tuberculosis developed by researchers at Oxford University. This vaccine produces higher levels of long-lasting cellular immunity when used together with the older TB vaccine BCG.Multiple cloning site: A multiple cloning site (MCS), also called a polylinker, is a short segment of DNA which contains many (up to ~20) restriction sites - a standard feature of engineered plasmids. Restriction sites within an MCS are typically unique, occurring only once within a given plasmid.Greyfriars, King's Lynn: Greyfriars, King's Lynn was a Franciscan friary in Norfolk, England. The tower, known as Greyfriars Tower () survives.Statnamic load test: The Statnamic load test is a type of test for assessing the load carrying capacity of deep foundations which is faster and less expensive than the static load test. The Statnamic test was conceived in 1985, with the first prototype tests carried out in 1988 through collaboration between Berminghammer Foundation Equipment of Canada and TNO Building Research of the Netherlands (Middendorp et al.Generalized vaccinia: Generalized vaccinia is a cutaneous condition that occurs 6-9 days after vaccination, characterized by a generalized eruption of skin lesions, and caused by the vaccinia virus.DPT vaccineImmunologic adjuvant: In immunology, an adjuvant is a component that potentiates the immune responses to an antigen and/or modulates it towards the desired immune responses. The word “adjuvant” comes from the Latin word adiuvare, meaning to help or aid.Coles PhillipsAnthrax Vaccine Immunization Program: The Anthrax Vaccine Immunization Program (AVIP), is the name of the policy set forth by the U.S.CTL-mediated cytotoxicityCell-mediated immunity: Cell mediated immunity is an immune response that does not involve antibodies, but rather involves the activation of phagocytes, antigen-specific cytotoxic T-lymphocytes, and the release of various cytokines in response to an antigen. Historically, the immune system was separated into two branches: humoral immunity, for which the protective function of immunization could be found in the humor (cell-free bodily fluid or serum) and cellular immunity, for which the protective function of immunization was associated with cells.Malcolm BrabantPlague vaccineCommunity-based clinical trial: Community-based clinical trials are clinical trials conducted directly through doctors and clinics rather than academic research facilities. They are designed to be administered through primary care physicians, community health centers and local outpatient facilities.Protein primary structure: The primary structure of a peptide or protein is the linear sequence of its amino acid structural units, and partly comprises its overall biomolecular structure. By convention, the primary structure of a protein is reported starting from the amino-terminal (N) end to the carboxyl-terminal (C) end.Rubella vaccineCocooning (immunization): Cocooning, also known as the Cocoon Strategy, is a vaccination strategy that has been recommended by the Centers for Disease Control and Prevention (CDC) in the United States since 2006. It aims to protect newborn infants from becoming infected with pertussis by administering DTaP/Tdap (tetanus, diphtheria and acellular pertussis) booster vaccine to mothers, family members and any individuals who would come into regular contact with the newborn infant.PMHC cellular microarray: PMHC cellular microarrays are a type of cellular microarray that has been spotted with pMHC complexes peptide-MHC class I or peptide-MHC class II.Virus-like particle: Virus-like particles resemble viruses, but are non-infectious because they do not contain any viral genetic material. The expression of viral structural proteins, such as Envelope or Capsid, can result in the self-assembly of virus like particles (VLPs).Influenza A virus subtype H1N1: Influenza A (H1N1) virus is the subtype of influenza A virus that was the most common cause of human influenza (flu) in 2009, and is associated with the 1918 outbreak known as the Spanish Flu.Nef (protein): coordinates.Global Vaccines: Global Vaccines, Inc is a mission-driven non-profit company applying state-of-the-art science and innovative business strategies to design and develop affordable vaccines for people in poor countries.Gross pathology: Gross pathology refers to macroscopic manifestations of disease in organs, tissues, and body cavities. The term is commonly used by anatomical pathologists to refer to diagnostically useful findings made during the gross examination portion of surgical specimen processing or an autopsy.International Network of Prison Ministries: The International Network of Prison Ministries (INPM) is a Dallas, Texas based crime prevention and rehabilitation trans-national organization. INPM functions through a website that serves as a clearinghouse for information about various Christian prison ministries.Cytomegalovirus vaccine: A Cytomegalovirus vaccine is a vaccine to prevent cytomegalovirus (CMV) infection or to prevent it re-activation in those who are already infected. As of 2014 no such a vaccine exists, although a number of vaccine candidates are under investigation.Universal Immunization Programme: Universal Immunization Programme is a vaccination program launched by the Government of India in 1985. It became a part of Child Survival and Safe Motherhood Programme in 1992 and is currently one of the key areasCD4 immunoadhesin: CD4 immunoadhesin is a recombinant fusion protein consisting of a combination of CD4 and the fragment crystallizable region.Nasal administration